2025
Ultrasound Guidance for Botulinum Toxin Injection of Muscles Innervated by the Facial Nerve: A Systematic Review of Anatomical Precision, Safety, and Outcomes
Chowdhury R, Schiff B, Lee Y, Mohan S. Ultrasound Guidance for Botulinum Toxin Injection of Muscles Innervated by the Facial Nerve: A Systematic Review of Anatomical Precision, Safety, and Outcomes. Aesthetic Surgery Journal 2025, sjaf175. PMID: 40971765, DOI: 10.1093/asj/sjaf175.Peer-Reviewed Original ResearchUltrasound guidanceBotulinum toxin injectionSystematic reviewLandmark-based techniqueAdverse eventsPatient satisfactionPatient-reported measuresHigh-resolution ultrasoundOff-target deliveryBotulinum toxin type AInjection of muscleRisk of biasCadaveric trialsRandomized Controlled TrialsToxin type ARhytid reductionFacial nerveFacial synkinesisClinical efficacyClinical outcomesProspective cohortClinical studiesBoNT-AFacial symmetryInjection accuracyBehavioral Eructation Retraining Protocol (BERP): A Novel Adjunct Behavioral Therapy for R‐CPD
Keltz A, Simmons K, Lerner M. Behavioral Eructation Retraining Protocol (BERP): A Novel Adjunct Behavioral Therapy for R‐CPD. The Laryngoscope 2025 PMID: 40662408, DOI: 10.1002/lary.32427.Peer-Reviewed Original ResearchR-CPDRetraining protocolsBotulinum toxinBTX injectionRetrograde cricopharyngeus dysfunctionSpeech-language pathology interventionSymptom resolutionBotulinum toxin injectionTraining patientsPatient reportsIncomplete symptom resolutionBehavioral interventionsBotulinum injectionBehavioral therapyIntervention optionsAdjunctive behavioral therapyPathology interventionRetrospective case seriesHead turnBody positionStandard of treatmentIncomplete symptom reliefInterventionSymptom recurrenceSymptom reliefEfficacy of anal botulinum toxin injection in children with functional constipation
Patel D, Saikumar P, Jayaraman M, Desai C, Rosen J, Rodriguez L. Efficacy of anal botulinum toxin injection in children with functional constipation. Journal Of Pediatric Gastroenterology And Nutrition 2025, 80: 956-962. PMID: 40123476, DOI: 10.1002/jpn3.70040.Peer-Reviewed Original ResearchConceptsResponse to therapyBotulinum toxin injectionFunctional constipationMedical therapyBotulinum toxinGroup 2Group 1No factorsGroup 3Side effectsRefractory to medical therapyResults of anorectal manometryDevelopmental delayDevelopment of side effectsPediatric age groupFrequency of BMPresence of developmental delayDose of botulinum toxinMedian doseMedian followAnorectal manometryMedian ageMulticenter studyBM frequencyLaxative regimens
2024
Botulinum Toxin Treatment of Psoriasis—A Comprehensive Review
Ghaseminejad-Bandpey A, Etemadmoghadam S, Jabbari B. Botulinum Toxin Treatment of Psoriasis—A Comprehensive Review. Toxins 2024, 16: 449. PMID: 39453225, PMCID: PMC11510791, DOI: 10.3390/toxins16100449.Peer-Reviewed Original ResearchConceptsOpen-label studyClinical trialsAnimal studiesPlacebo-controlled studyInjection of botulinum toxinPsoriatic skin lesionsLevels of interleukinsBotulinum toxin injectionOpen-labelDouble-blindBotulinum toxin treatmentCase reportInflammatory cellsPsoriatic plaquesSkin lesionsSmall dosesToxin injectionToxin treatmentLiterature searchBotulinum toxinRelevant articlesPsoriasisInterleukinHuman dataDoseClinical neurophysiology in the treatment of movement disorders: IFCN handbook chapter
Lefaucheur J, Moro E, Shirota Y, Ugawa Y, Grippe T, Chen R, Benninger D, Jabbari B, Attaripour S, Hallett M, Paulus W. Clinical neurophysiology in the treatment of movement disorders: IFCN handbook chapter. Clinical Neurophysiology 2024, 164: 57-99. PMID: 38852434, PMCID: PMC11418354, DOI: 10.1016/j.clinph.2024.05.007.Peer-Reviewed Original ResearchTranscranial alternating current stimulationTranscranial direct current stimulationLow-intensity transcranial electrical stimulationRepetitive transcranial magnetic stimulationSpinal cord stimulationCurrent stimulationMovement disordersTreated with botulinum toxin injectionsPulse generatorTranscranial electrical stimulationBotulinum toxin injectionIdentification of musclesShort-term clinical impactDirect current stimulationDeep brain stimulationAt-home useTherapeutic neuromodulationChronic diseasesTranscranial applicationTranscranial magnetic stimulationSurgical implantation of electrodesTreatment of movement disordersFUS stimulationAxial signsNeuromodulation techniques
2023
Diagnosing and managing dysphagia in inclusion body myositis: a systematic review
Ambrocio K, Garand K, Roy B, Bhutada A, Malandraki G. Diagnosing and managing dysphagia in inclusion body myositis: a systematic review. Rheumatology 2023, 62: 3227-3244. PMID: 37115631, DOI: 10.1093/rheumatology/kead194.Peer-Reviewed Original ResearchConceptsManagement of dysphagiaSystematic reviewImpact of dysphagiaPreferred Reporting ItemsLow-quality evidenceBotulinum toxin injectionReporting ItemsOutcome measuresInclusion criteriaDisease managementToxin injectionInterventionBehavioral therapyCP myotomyQuality assessmentSwallowing outcomesSwallowing abnormalitiesPersonsInclusion body myositisDysphagiaInclusionAssessmentReviewDebilitating clinical featuresAssessment procedures
2022
Essential components of care in a multidisciplinary headache center: Perspectives from headache neurology specialists
Goldman RE, Damush TM, Kuruvilla DE, Lindsey H, Baird S, Riley S, BS L, Grinberg AS, Seng EK, Fenton BT, Sico JJ. Essential components of care in a multidisciplinary headache center: Perspectives from headache neurology specialists. Headache The Journal Of Head And Face Pain 2022, 62: 306-318. PMID: 35293614, DOI: 10.1111/head.14277.Peer-Reviewed Original ResearchConceptsMultidisciplinary headache centerHeadache centerHeadache careNeurology specialistsChronic headacheIntegrative health modalitiesBotulinum toxin injectionImmersion/crystallization techniqueType of careSemi-structured telephone interviewsBehavioral health practitionersCognitive behavioral therapyToxin injectionMultidisciplinary careNerve blockPain managementUnsuccessful treatmentHeadache specialistsNew medicationsPhysical therapySuccessful careMultiple doctorsPatientsOccupational therapySleep medicine
2020
The Yale technique of Botulinum toxin injections for Parkinson's disease and essential tremor - Customised treatment for effective and safe therapy
Mittal S, Jabbari B. The Yale technique of Botulinum toxin injections for Parkinson's disease and essential tremor - Customised treatment for effective and safe therapy. Parkinsonism & Related Disorders 2020, 79: e57. DOI: 10.1016/j.parkreldis.2020.06.220.Peer-Reviewed Original ResearchBotulinum toxin injection
2017
Modified approach for pediatric external cricopharyngeal myotomy
Mohan S, Bowe S, Hirner L, Zar-Kessler C, Hartnick C. Modified approach for pediatric external cricopharyngeal myotomy. International Journal Of Pediatric Otorhinolaryngology 2017, 105: 111-114. PMID: 29447795, DOI: 10.1016/j.ijporl.2017.12.019.Peer-Reviewed Original ResearchConceptsOpen cricopharyngeal myotomyCricopharyngeal myotomyCricopharyngeal achalasiaUpper esophageal sphincter relaxationPediatric cricopharyngeal achalasiaBotulinum toxin injectionEsophageal sphincter relaxationRecurrent laryngeal nerveBalloon dilationEsophageal perforationSphincter relaxationToxin injectionLaryngeal nerveOropharyngeal dysphagiaPosterior midlineImportant causeRisky procedureYoung malesAchalasiaMyotomyDysphagiaCricopharyngeusNervePathophysiology
2016
Gender differences in onabotulinum toxin A dosing for adductor spasmodic dysphonia
Lerner MZ, Lerner BA, Patel AA, Blitzer A. Gender differences in onabotulinum toxin A dosing for adductor spasmodic dysphonia. The Laryngoscope 2016, 127: 1131-1134. PMID: 27633917, DOI: 10.1002/lary.26265.Peer-Reviewed Original ResearchConceptsAdductor spasmodic dysphoniaSpasmodic dysphoniaOnabotulinum toxinChart reviewFemale groupOnabotulinum Toxin A InjectionsRetrospective chart reviewBotulinum toxin injectionSenior author's databaseAbductor spasmodic dysphoniaIndependent sample twoA injectionAverage followSymptom controlOromandibular dystoniaToxin injectionFemale patientsRetrospective reviewAlternate diagnosisBotulinum toxinAntibody formationFemale genderPossible inverse relationshipInclusion criteriaThyroarytenoid muscle
2015
Testing the effects of pre-processing on voxel based morphometry analysis
Chaitanya C, Koirala N, Mideksa K, Anwar A, Schmidt G, Deuschl G, Groppa S, Muthuraman M. Testing the effects of pre-processing on voxel based morphometry analysis. Annual International Conference Of The IEEE Engineering In Medicine And Biology Society (EMBC) 2015, 2015: 4302-4305. PMID: 26737246, DOI: 10.1109/embc.2015.7319346.Peer-Reviewed Original ResearchConceptsGray matter volumeGray matter differencesDifferent time pointsTime pointsMagnetic resonance imagesBotulinum toxin injectionEvidence-based therapiesStructural grey matter differencesVoxel-wise comparisonBase therapyToxin injectionCross-sectional data analysisBotulinum toxinMatter volumeRespective musclesMorphometry analysisLongitudinal data analysisPatientsLongitudinal analysisResonance imagesInjectionBrainTreatmentSecond aimStatistical analysis
2007
Effect of Botulinum Toxin Type A on Tear Production After Treatment of Lateral Canthal Rhytids
Arat Y, Yen M. Effect of Botulinum Toxin Type A on Tear Production After Treatment of Lateral Canthal Rhytids. Ophthalmic Plastic And Reconstructive Surgery 2007, 23: 22-24. PMID: 17237684, DOI: 10.1097/iop.0b013e31802dfca7.Peer-Reviewed Original ResearchConceptsSchirmer test resultsLateral canthal rhytidsTear productionBotulinum toxin type ADry eyeToxin type ATreatment of lateral canthal rhytidsFollow-upSchirmer 1 testUnits of botulinum toxinDry-eye symptomsDecreased tear productionBotulinum toxinCrow's feet areasMonths follow-upBotulinum toxin type A injectionBotulinum toxin injectionEffect of botulinum toxin type ADry-eyeType ASchirmerPatientsToxin injectionCrow's-feetStatistical difference
2000
Pharmacologic Treatment of Tic Disorders
Scahill L, Chappell P, King R, Leckman J. Pharmacologic Treatment of Tic Disorders. Child And Adolescent Psychiatric Clinics Of North America 2000, 9: 99-117. PMID: 10674192, DOI: 10.1016/s1056-4993(18)30137-8.Peer-Reviewed Original ResearchConceptsTic disordersTreatment of ADHDAtypical neurolepticsLong-term side effectsNewer atypical neurolepticsFirst-line treatmentTreatment of ticsBotulinum toxin injectionMore studiesUse of stimulantsNonstimulant medicationsToxin injectionPharmacologic treatmentPsychiatric comorbidityStandard treatmentTraditional neurolepticsTarget symptomsSide effectsStimulant medicationMedicationsNeurolepticsAdverse effectsComorbid ADHDDisordersTreatment planning
1999
Treatment of Achalasia
Seelig M, DeVault K, Seelig S, Klingler P, Branton S, Floch N, Bammer T, Hinder R. Treatment of Achalasia. Journal Of Clinical Gastroenterology 1999, 28: 202-207. PMID: 10192604, DOI: 10.1097/00004836-199904000-00004.Peer-Reviewed Original ResearchConceptsPrimary treatment optionTreatment optionsLong-term relief of symptomsMinimally invasive surgical techniquesLong-term reliefRelief of symptomsInvasive surgical techniquesLower esophageal sphincterBotulinum toxin injectionShort-term reliefPneumatic dilationHeller myotomyLaparoscopic proceduresAntireflux procedureTherapeutic optionsMotility disordersSurgical techniqueEsophageal sphincterEffective treatmentToxin injectionAchalasiaDilatationPatientsOptionsMyotomy
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