2024
Beyond the serotonin deficit hypothesis: communicating a neuroplasticity framework of major depressive disorder
Page C, Epperson C, Novick A, Duffy K, Thompson S. Beyond the serotonin deficit hypothesis: communicating a neuroplasticity framework of major depressive disorder. Molecular Psychiatry 2024, 29: 3802-3813. PMID: 38816586, PMCID: PMC11692567, DOI: 10.1038/s41380-024-02625-2.Peer-Reviewed Original ResearchDepressive disorderTreatment of MDDEmotional brain circuitsMental health crisisMonoaminergic antidepressantsSerotonergic antidepressantsEmotional processingDeficit hypothesisBrain circuitsMDDBehavioral functionsHypothesis explanationAntidepressantsInsufficient supportive evidenceSerotoninNeuromodulation techniquesPreclinical researchNegative biasDisordersPersistent negative biasSupportive evidenceCliniciansPsychotherapyEffective treatmentPsychedelicsClinical neurophysiology in the treatment of movement disorders: IFCN handbook chapter
Lefaucheur J, Moro E, Shirota Y, Ugawa Y, Grippe T, Chen R, Benninger D, Jabbari B, Attaripour S, Hallett M, Paulus W. Clinical neurophysiology in the treatment of movement disorders: IFCN handbook chapter. Clinical Neurophysiology 2024, 164: 57-99. PMID: 38852434, PMCID: PMC11418354, DOI: 10.1016/j.clinph.2024.05.007.Peer-Reviewed Original ResearchTranscranial alternating current stimulationTranscranial direct current stimulationLow-intensity transcranial electrical stimulationRepetitive transcranial magnetic stimulationSpinal cord stimulationCurrent stimulationMovement disordersTreated with botulinum toxin injectionsPulse generatorTranscranial electrical stimulationBotulinum toxin injectionIdentification of musclesShort-term clinical impactDirect current stimulationDeep brain stimulationAt-home useTherapeutic neuromodulationChronic diseasesTranscranial applicationTranscranial magnetic stimulationSurgical implantation of electrodesTreatment of movement disordersFUS stimulationAxial signsNeuromodulation techniquesStriatum- and Cerebellum-Modulated Epileptic Networks Varying Across States with and without Interictal Epileptic Discharges
Jiang S, Pei H, Chen J, Li H, Liu Z, Wang Y, Gong J, Wang S, Li Q, Duan M, Calhoun V, Yao D, Luo C. Striatum- and Cerebellum-Modulated Epileptic Networks Varying Across States with and without Interictal Epileptic Discharges. International Journal Of Neural Systems 2024, 34: 2450017. PMID: 38372049, DOI: 10.1142/s0129065724500175.Peer-Reviewed Original ResearchConceptsSalience networkSensorimotor cortexFunctional magnetic resonance imaging dataModerating effectInterictal epileptic dischargesIdiopathic generalized epilepsyMagnetic resonance imaging dataInteraction of regionsDecreased connectivityStriatumDMNThalamocortical circuitsCortical interactionsSimultaneous electroencephalogramCortical targetsEpileptic dischargesCerebellumThalamusHierarchical connectionEpileptic networkNeuromodulation techniquesIndirect moderating effectStateCryptogenic etiology
2021
Imaging of Neuromodulation and Surgical Interventions for Epilepsy
Adin ME, Spencer DD, Damisah E, Herlopian A, Gerrard JL, Bronen RA. Imaging of Neuromodulation and Surgical Interventions for Epilepsy. American Journal Of Neuroradiology 2021, 42: 1742-1750. PMID: 34353787, PMCID: PMC8562735, DOI: 10.3174/ajnr.a7222.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsSurgical interventionPostoperative imaging findingsMultiple subpial transectionsComprehensive Epilepsy CenterGroup of patientsVagus nerve stimulationDeep brain stimulationInvasive treatment decisionsNew surgical interventionLobar resectionSubpial transectionMedical therapyEpilepsy centersImaging findingsNerve stimulationTreatment algorithmTherapeutic optionsTreatment modalitiesEpilepsy interventionsPotential complicationsEpilepsy casesTreatment decisionsBrain stimulationResponsive neurostimulationNeuromodulation techniques
2020
Precision non-implantable neuromodulation therapies: a perspective for the depressed brain
Borrione L, Bellini H, Razza L, Avila A, Baeken C, Brem A, Busatto G, Carvalho A, Chekroud A, Daskalakis Z, Deng Z, Downar J, Gattaz W, Loo C, Lotufo P, da Graça M. Martin M, McClintock S, O’Shea J, Padberg F, Passos I, Salum G, Vanderhasselt M, Fraguas R, Benseñor I, Valiengo L, Brunoni A. Precision non-implantable neuromodulation therapies: a perspective for the depressed brain. Brazilian Journal Of Psychiatry 2020, 42: 403-419. PMID: 32187319, PMCID: PMC7430385, DOI: 10.1590/1516-4446-2019-0741.Peer-Reviewed Original ResearchConceptsMajor depressive disorderSide effectsCurrent first-line treatmentMultiple medication trialsMagnetic seizure therapyFirst-line treatmentCognitive side effectsTranscranial direct current stimulationTranscranial magnetic stimulationDirect current stimulationCognitive behavioral therapyCost-effectiveness analysisClinical respondersSeizure therapyElectroconvulsive therapyMedication trialsPathophysiological mechanismsClinical trialsDepressed patientsDepressive disorderDepressed brainMagnetic stimulationNeuromodulation techniquesCurrent stimulationTherapy
2019
Transcranial direct current stimulation for Obsessive-Compulsive Disorder: patient selection and perspectives
da Silva R, Brunoni A, Miguel E, Shavitt R. Transcranial direct current stimulation for Obsessive-Compulsive Disorder: patient selection and perspectives. Neuropsychiatric Disease And Treatment 2019, 15: 2663-2669. PMID: 31571882, PMCID: PMC6754675, DOI: 10.2147/ndt.s184839.Peer-Reviewed Original ResearchTranscranial direct current stimulationDirect current stimulationSevere obsessive-compulsive disorderObsessive-compulsive disorderCurrent stimulationPrevious conventional treatmentSafe tolerability profileFirst treatment optionImprovement of OCDModalities of treatmentNon-invasive neuromodulation techniqueAlternative treatment modalityPubMed/MEDLINETime of assessmentTolerability profileClinical characteristicsClinical presentationPatient selectionPsychiatric comorbidityPharmacological treatmentTreatment optionsTreatment modalitiesClinical severityNeuromodulation techniquesConventional treatment
2016
Transcranial direct current stimulation for treatment-resistant obsessive-compulsive disorder: report on two cases and proposal for a randomized, sham-controlled trial
da Silva R, Brunoni A, Miguel E, Shavitt R. Transcranial direct current stimulation for treatment-resistant obsessive-compulsive disorder: report on two cases and proposal for a randomized, sham-controlled trial. Sao Paulo Medical Journal 2016, 134: 446-450. PMID: 27901245, PMCID: PMC10871858, DOI: 10.1590/1516-3180.2016.0155010716.Peer-Reviewed Original ResearchConceptsTreatment-resistant obsessive-compulsive disorderTranscranial direct current stimulationObsessive-compulsive disorderDirect current stimulationClinical trialsCurrent stimulationSham-controlled trialSerotonin reuptake inhibitorsSupplementary motor cortexPrimary obsessive-compulsive disorderCognitive behavioral therapySecondary outcomesPrimary outcomeReuptake inhibitorsSham interventionFirst patientCortical excitabilityMotor cortexUniversity HospitalWeek 4YBOCS scoresNeuromodulation techniquesNon-invasive techniqueBrain circuitsPatients
2015
Transcranial direct current stimulation in obsessive–compulsive disorder: emerging clinical evidence and considerations for optimal montage of electrodes
Senço N, Huang Y, D’Urso G, Parra L, Bikson M, Mantovani A, Shavitt R, Hoexter M, Miguel E, Brunoni A. Transcranial direct current stimulation in obsessive–compulsive disorder: emerging clinical evidence and considerations for optimal montage of electrodes. Expert Review Of Medical Devices 2015, 12: 381-391. PMID: 25982412, PMCID: PMC5777161, DOI: 10.1586/17434440.2015.1037832.Peer-Reviewed Original ResearchConceptsTranscranial direct current stimulationDirect current stimulationSystematic reviewCurrent stimulationPotential new treatmentPre-supplementary motor areaPubMed/MEDLINEObsessive-compulsive disorder (OCD) treatmentDeep brain stimulation trialsClinical evidenceObsessive-compulsive disorderStimulation trialsDBS trialsMotor areaRTMS targetsMagnetic stimulationEligibility criteriaNeuromodulation techniquesStimulation targetsDisorder treatmentNew treatmentsBrain circuitsDifferent electrode montagesTDCS montageTrials
2000
A proposed ethical framework for interventional cognitive neuroscience: A consideration of deep brain stimulation impaired consciousness
Fins J. A proposed ethical framework for interventional cognitive neuroscience: A consideration of deep brain stimulation impaired consciousness. Neurological Research 2000, 22: 273-278. PMID: 10769820, DOI: 10.1080/01616412.2000.11740670.Peer-Reviewed Original ResearchConceptsCognitive neuroscienceEthical frameworkEvaluation of study designHuman subjects researchTraumatic brain injuryVulnerable study populationEthical obligationParadigm caseDeep brain stimulationScientific inquirySubjects researchSocietal consensusBrain injuryBrain stimulationNeuromodulation techniquesNeuroscienceClinical researchResearch strategyTherapeutic interventionsAttendant developmentObligations
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