2025
US of the Neck beyond the Thyroid Gland: Parathyroid Glands.
Khot R, Dixe de Oliveira Santo I, Shen L, Itani M, Sailer A, Kirsch J, Revzin M. US of the Neck beyond the Thyroid Gland: Parathyroid Glands. RadioGraphics 2025, 45: e240182. PMID: 40440190, DOI: 10.1148/rg.240182.Peer-Reviewed Original ResearchConceptsParathyroid lesionsThyroid nodulesMinimally invasive parathyroidectomyFour-dimensional CTImaging modalitiesAbnormal parathyroid tissueSolitary parathyroid adenomaDetection of thyroid nodulesAlternative imaging modalityHyperparathyroidism managementNeck USEctopic glandsParathyroid adenomaParathyroid hyperplasiaParathyroid imagingLymph nodesParathyroid tissueParathyroid glandsMultiple adenomasThyroid glandImaging evaluationAdenomasPathological conditionsGlandThyroid
2023
Prediagnostic serum concentrations of per‐ and polyfluoroalkyl substances and risk of papillary thyroid cancer in the Finnish Maternity Cohort
Madrigal J, Troisi R, Surcel H, Öhman H, Kivelä J, Kiviranta H, Rantakokko P, Koponen J, Medgyesi D, Kitahara C, McGlynn K, Sampson J, Albert P, Ward M, Jones R. Prediagnostic serum concentrations of per‐ and polyfluoroalkyl substances and risk of papillary thyroid cancer in the Finnish Maternity Cohort. International Journal Of Cancer 2023, 154: 979-991. PMID: 37902275, PMCID: PMC11286200, DOI: 10.1002/ijc.34776.Peer-Reviewed Original ResearchFinnish Maternity CohortPapillary thyroid cancerThyroid cancerOdds ratioPrediagnostic serum concentrationsPrediagnostic serum levelsConfidence intervalsCase-control studyConditional logistic regressionThyroid cancer riskPapillary thyroid cancer riskPerfluorononanoic acidPerfluorodecanoic acidPerfluorohexane sulfonic acidHigh exposure levelsMedian ageSerum levelsSerum concentrationsCalendar periodCancer riskBirth cohortThyroid glandLogistic regressionCancerClear associationMultimodality pictorial review of IgG4-related disease in the abdomen and pelvis
Czerniak S, Rao A, Mathur M. Multimodality pictorial review of IgG4-related disease in the abdomen and pelvis. Abdominal Radiology 2023, 48: 3147-3161. PMID: 37407744, DOI: 10.1007/s00261-023-03996-w.Peer-Reviewed Original ResearchConceptsIgG4-RDPictorial reviewMultiple organsVariable imaging manifestationsImmune-mediated diseasesLymph nodesGlucocorticoid treatmentImaging manifestationsPathologic dataBile ductDefinite diagnosisRadiographic characteristicsImaging appearancesConclusionThe presenceTimely diagnosisClinical considerationsThyroid glandDiseaseSalivary glandsAbdomenPelvisSoft tissueDiagnosisGlandOrgansAutoimmune thyroid diseases as a cost of physiological autoimmune surveillance
Milo T, Korem Kohanim Y, Toledano Y, Alon U. Autoimmune thyroid diseases as a cost of physiological autoimmune surveillance. Trends In Immunology 2023, 44: 365-371. PMID: 37061365, DOI: 10.1016/j.it.2023.03.007.Peer-Reviewed Original ResearchConceptsGraves' diseaseHashimoto's thyroiditisT cellsAutoimmune surveillanceAutoreactive T cellsAutoimmune thyroid diseaseToxic nodulesThyroid antigensThyroid diseaseClinical manifestationsProduction of antibodiesAutoimmune diseasesClinical phenotypeThyroid glandHumoral responseMutant cellsRisk factorsThyroidSusceptible individualsDiseasePhysiological processes
2022
Primary Mesenchymal Tumors of the Thyroid Gland: A Modern Retrospective Cohort Including the First Case of TFE3-Translocated Malignant Perivascular Epithelioid Cell Tumor (PEComa)
Zhang L, Lubin D, Sinard JH, Dickson BC, Antonescu CR, Wu H, Panni RZ, Dogan S, Untch BR, Ghossein RA, Xu B. Primary Mesenchymal Tumors of the Thyroid Gland: A Modern Retrospective Cohort Including the First Case of TFE3-Translocated Malignant Perivascular Epithelioid Cell Tumor (PEComa). Head And Neck Pathology 2022, 16: 716-727. PMID: 35218514, PMCID: PMC9424363, DOI: 10.1007/s12105-022-01428-7.Peer-Reviewed Original ResearchConceptsMalignant perivascular epithelioid cell tumorPerivascular epithelioid cell tumorEpithelioid cell tumorPrimary mesenchymal tumorsMesenchymal tumorsThyroid glandCell tumorsPeripheral nerve sheath tumorsNerve sheath tumorsSmall case seriesBiphasic synovial sarcomaOnly case reportsSolitary fibrous tumorAnaplastic thyroid carcinomaMulti-centric cohortFirst caseRetrospective cohortEpithelioid hemangioendotheliomaSheath tumorsTertiary centerCase seriesClinicopathologic featuresFemale patientsSynovial sarcomaCase reportChapter 11 Hormonal control of growth
Holt E, Lupsa B, Lee G, Bassyouni H, Peery H. Chapter 11 Hormonal control of growth. 2022, 335-379. DOI: 10.1016/b978-0-12-815844-9.00011-7.ChaptersChapter 3 Thyroid gland
Holt E, Lupsa B, Lee G, Bassyouni H, Peery H. Chapter 3 Thyroid gland. 2022, 75-99. DOI: 10.1016/b978-0-12-815844-9.00003-8.ChaptersChapter 10 Hormonal regulation of calcium balance
Holt E, Lupsa B, Lee G, Bassyouni H, Peery H. Chapter 10 Hormonal regulation of calcium balance. 2022, 303-333. DOI: 10.1016/b978-0-12-815844-9.00010-5.Chapters
2020
Thyroid tissue outside the thyroid gland: Differential diagnosis and associated diagnostic challenges
Barbieri A, Prasad ML, Gilani SM. Thyroid tissue outside the thyroid gland: Differential diagnosis and associated diagnostic challenges. Annals Of Diagnostic Pathology 2020, 48: 151584. PMID: 32871503, DOI: 10.1016/j.anndiagpath.2020.151584.Peer-Reviewed Original ResearchConceptsDifferential diagnostic considerationsThyroid tissueThyroid glandLymph nodesDiagnostic challengeDifferential diagnosisDiagnostic considerationsLateral neck lymph nodesNeck lymph nodesRoutine daily practiceThyroglossal duct cystLocation of lesionsMalignant differential diagnosisDuct cystDefinitive diagnosisLingual thyroidAnatomic locationClinical settingThyroid folliclesDaily practiceDiagnosisParasitic nodulesGlandTissueHistologicPearls and Pitfalls in Pediatric Thyroid Imaging
Silva CT, Navarro OM. Pearls and Pitfalls in Pediatric Thyroid Imaging. Seminars In Ultrasound CT And MRI 2020, 41: 421-432. PMID: 32980089, DOI: 10.1053/j.sult.2020.05.007.Peer-Reviewed Original ResearchConceptsDiffuse thyroid enlargementThyroid enlargementCongenital hypothyroidismThyroid nodulesThyroid imagingPediatric age groupRole of imagingRisk of malignancyPermanent congenital hypothyroidismGraves' diseasePediatric populationHashimoto's diseaseNodular hyperplasiaPapillary carcinomaThyroid glandAccurate diagnosisAge groupsThyroid dysgenesisHypothyroidismDiseaseChildrenTeenage girlsImagingManagement recommendationsEnlargement
2019
SUN-613 Papillary Thyroid Carcinoma in a Pediatric Patient with Beta Thalassemia
Choleva L, Rapaport R, Romero C, Yau M, Sethuram S, Gujral J, Wallach E, Wilkes M. SUN-613 Papillary Thyroid Carcinoma in a Pediatric Patient with Beta Thalassemia. Journal Of The Endocrine Society 2019, 3: sun-613. PMCID: PMC6553241, DOI: 10.1210/js.2019-sun-613.Peer-Reviewed Original ResearchPapillary thyroid carcinomaThyroid carcinomaBeta thalassemiaPediatric patientsRight lobeThyroid cancerChronic red blood cell transfusionsThyroid glandRed blood cell transfusionEnlarged right lobePalpable lymph nodesBlood cell transfusionFrequent blood transfusionsPapillary thyroid cancerMonth old femaleFine-needle aspirationCervical chainCell transfusionTotal thyroidectomyPostoperative courseBlood transfusionLymph nodesFerritin levelsHypoechoic massSecondary amenorrheaSYSTEMIC AMYLOIDOSIS IN A POPULATION OF PRONGHORN ANTELOPE (ANTILOCAPRA AMERICANA)
Martinez ME, Zimmerman D, Seeley KE, Zhang L, Bapodra P, Cianciolo RE. SYSTEMIC AMYLOIDOSIS IN A POPULATION OF PRONGHORN ANTELOPE (ANTILOCAPRA AMERICANA). Journal Of Zoo And Wildlife Medicine 2019, 50: 147-158. PMID: 31120673, DOI: 10.1638/2018-0055.Peer-Reviewed Original ResearchConceptsChronic inflammationClinical historySystemic amyloidosisSerum amyloid ACases of amyloidosisPresence of amyloidosisΓ-globulin levelsNegative energy balanceHistologic evidenceAdrenal glandGlomerular depositsAmyloid ARenal specimensGlobulin levelsAmyloid presentHistologic examinationPostmortem findingsRenal tissueGastrointestinal tractNormal rangeRetrospective investigationThyroid glandSignificant associationAmyloidosisUnderlying cause
2017
Balancing the benefits and harms of thyroid cancer surveillance in survivors of Childhood, adolescent and young adult cancer: Recommendations from the international Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium
Clement SC, Kremer LCM, Verburg FA, Simmons JH, Goldfarb M, Peeters RP, Alexander EK, Bardi E, Brignardello E, Constine LS, Dinauer CA, Drozd VM, Felicetti F, Frey E, Heinzel A, van den Heuvel-Eibrink MM, Huang SA, Links TP, Lorenz K, Mulder RL, Neggers SJ, van Dijkum E, Oeffinger KC, van Rijn RR, Rivkees SA, Ronckers CM, Schneider AB, Skinner R, Wasserman JD, Wynn T, Hudson MM, Nathan PC, van Santen HM. Balancing the benefits and harms of thyroid cancer surveillance in survivors of Childhood, adolescent and young adult cancer: Recommendations from the international Late Effects of Childhood Cancer Guideline Harmonization Group in collaboration with the PanCareSurFup Consortium. Cancer Treatment Reviews 2017, 63: 28-39. PMID: 29202445, DOI: 10.1016/j.ctrv.2017.11.005.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsDifferentiated thyroid cancerChildhood Cancer Guideline Harmonization GroupInternational Late EffectsThyroid cancer surveillanceYoung adult cancerPanCareSurFup ConsortiumCancer surveillanceLate effectsAdult cancersInternational multidisciplinary panelSurvivors of childhoodTreatment of childhoodRelevant medical specialtiesHealth care providersNeck palpationSurveillance recommendationsSurveillance modalitiesThyroid cancerMultidisciplinary panelScreening practicesConsensus recommendationsThyroid ultrasoundCare providersAppropriate managementThyroid glandMetastatic thyroid carcinoma without identifiable primary tumor within the thyroid gland: a retrospective study of a rare phenomenon
Xu B, Scognamiglio T, Cohen PR, Prasad ML, Hasanovic A, Tuttle RM, Katabi N, Ghossein RA. Metastatic thyroid carcinoma without identifiable primary tumor within the thyroid gland: a retrospective study of a rare phenomenon. Human Pathology 2017, 65: 133-139. PMID: 28552827, PMCID: PMC5571865, DOI: 10.1016/j.humpath.2017.05.013.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBiomarkers, TumorCarcinomaCarcinoma, PapillaryCell DifferentiationDNA Mutational AnalysisFemaleGenetic Predisposition to DiseaseHumansImmunohistochemistryLymphatic MetastasisMaleMiddle AgedMutationNeoplasm GradingNeoplasms, Unknown PrimaryPhenotypeProto-Oncogene Proteins B-rafRetrospective StudiesThyroid Cancer, PapillaryThyroid Carcinoma, AnaplasticThyroid NeoplasmsConceptsPapillary thyroid carcinomaIdentifiable primary tumorThyroid carcinomaAnaplastic thyroid carcinomaMetastatic diseasePrimary tumorThyroid glandMetastatic papillary thyroid carcinomaEvidence of recurrenceMetastatic nodal diseaseMetastatic thyroid carcinomaTall cell variantBRAF V600E immunohistochemistryThyroid primaryNodal diseaseNeck compartmentDistant metastasisPathologic featuresRetrospective studyAnaplastic carcinomaUnknown causeMost tumorsCarcinomaPatientsThyroid tumors
2016
Mammary analog secretory carcinoma of the thyroid gland: A primary thyroid adenocarcinoma harboring ETV6–NTRK3 fusion
Dogan S, Wang L, Ptashkin R, Dawson R, Shah J, Sherman E, Tuttle R, Fagin J, Klimstra D, Katabi N, Ghossein R. Mammary analog secretory carcinoma of the thyroid gland: A primary thyroid adenocarcinoma harboring ETV6–NTRK3 fusion. Modern Pathology 2016, 29: 985-995. PMID: 27282352, PMCID: PMC5019170, DOI: 10.1038/modpathol.2016.115.Peer-Reviewed Original ResearchMeSH KeywordsAdenocarcinomaAgedBiomarkers, TumorDisease ProgressionDisease-Free SurvivalFemaleGene FusionGene RearrangementGenetic Predisposition to DiseaseHumansImmunohistochemistryIn Situ Hybridization, FluorescenceMaleMammary Analogue Secretory CarcinomaMiddle AgedNeoplasm GradingNeoplasm Recurrence, LocalNeoplasm StagingOncogene Proteins, FusionPhenotypeThyroid NeoplasmsTreatment OutcomeConceptsMammary analog secretory carcinomaFree of diseaseETV6-NTRK3 fusionPapillary thyroid carcinomaS-100 proteinFluorescence in situ hybridizationSecretory carcinomaETV6 rearrangementThyroid carcinomaGCDFP-15TTF-1Minority of papillary thyroid carcinomasWell-differentiated papillary thyroid carcinomaThyroid glandS-100Papillary thyroid carcinoma componentAssociated with long-term survivalETV6-NTRK3 gene fusionSalivary glandsThyroid carcinoma componentFollicular cell originLow-grade tumorsHigher T stageLocally aggressive tumorSalivary gland counterpartsRecurrent Thyrotoxicosis due to Both Graves’ Disease and Hashimoto’s Thyroiditis in the Same Three Patients
Schaffer A, Puthenpura V, Marshall I. Recurrent Thyrotoxicosis due to Both Graves’ Disease and Hashimoto’s Thyroiditis in the Same Three Patients. Case Reports In Endocrinology 2016, 2016: 6210493. PMID: 27340576, PMCID: PMC4906178, DOI: 10.1155/2016/6210493.Peer-Reviewed Original ResearchGraves' diseaseHashimoto's thyroiditisDisease processRecurrence of thyrotoxicosisAutoimmune disease processSeparate disease processesAntithyroid medicationRadioablation therapyRecurrent thyrotoxicosisThree patientsInitial presentationCase reportThyrotoxicosisThyroiditisThyroid glandDiseaseUnique genetic differencesMonozygotic twinsPatientsTemporary resolutionHashitoxicosisMedicationsRecurrenceTherapy
2013
Parathyroid Localization and Implications for Clinical Management
Kunstman JW, Kirsch JD, Mahajan A, Udelsman R. Parathyroid Localization and Implications for Clinical Management. The Journal Of Clinical Endocrinology & Metabolism 2013, 98: 902-912. PMID: 23345096, DOI: 10.1210/jc.2012-3168.Peer-Reviewed Original ResearchConceptsParathyroid localizationPrimary hyperparathyroidismRadiation exposurePrevalence of hyperparathyroidismInvasive surgical approachExtensive clinical experienceNoninvasive imaging techniquesSignificant radiation exposureParathyroid arteriographySurgical candidatesFocused parathyroidectomyRefractory diseaseParathyroid surgeryParathyroid pathologyPreoperative localizationSurgical approachClinical managementClinical trialsExquisite anatomical detailComputed tomographyClinical experienceNuclear scintigraphyThyroid glandHyperparathyroidismMultidisciplinary collaboration
2012
GSTO2*N142D gene polymorphism associated with hypothyroidism in Italian patients
Piacentini S, Monaci PM, Polimanti R, Manfellotto D, Fuciarelli M. GSTO2*N142D gene polymorphism associated with hypothyroidism in Italian patients. Molecular Biology Reports 2012, 40: 1967-1971. PMID: 23079717, DOI: 10.1007/s11033-012-2253-0.Peer-Reviewed Original ResearchConceptsGST gene polymorphismsGene polymorphismsOxidative stressItalian patientsGST null polymorphismsBiomarkers of inflammationAnti-inflammatory responseLevel of inflammationLogistic regression analysisThyroid hormone productionPhase II enzymesCase-control populationRisk factorsHypothyroid individualsEndocrinal diseasesInflammation disordersPCR-RFLP methodHypothyroidismNull polymorphismThyroid glandGenotype distributionHormone productionGlutathione S-transferaseInflammationPatientsEmbryology and Surgical Anatomy of the Thyroid and Parathyroid Glands
Stewart W, Rizzolo L. Embryology and Surgical Anatomy of the Thyroid and Parathyroid Glands. 2012, 15-23. DOI: 10.1007/978-3-642-23459-0_2.Chapters
2009
Tumors of Thyroid Gland: Non-C cell Tumors
Khan A, Prasad M. Tumors of Thyroid Gland: Non-C cell Tumors. Current Clinical Pathology 2009, 41-81. DOI: 10.1007/978-1-60327-396-1_5.ChaptersCell tumorsFollicular patterned tumorsSurgical pathology practiceLining epithelial cellsThyroid cancer progressionCommon malignancyDifferentiated carcinomaPathological correlationAnaplastic carcinomaCommon tumorsDiagnostic challengeAncillary studiesCytomorphologic featuresPapillary carcinomaThyroid tumorsThyroid glandAccurate diagnosisThyroid hormonesTumorsThyroid lesionsPathology practiceEndocrine systemCarcinomaCancer progressionEpithelial cells
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