2023
Effectiveness of a group-based Diabetes Prevention Education Program (DiPEP) in a population with pre-diabetes: a cluster randomised controlled trial in Nepal
Shakya P, Shrestha A, Bajracharya M, Shrestha A, Kulseng B, Karmacharya B, Shrestha S, Das S, Shrestha I, Barun K, Shrestha N, Skovlund E, Sen A. Effectiveness of a group-based Diabetes Prevention Education Program (DiPEP) in a population with pre-diabetes: a cluster randomised controlled trial in Nepal. BMJ Nutrition Prevention & Health 2023, 6: 253-263. PMID: 38264365, PMCID: PMC10800278, DOI: 10.1136/bmjnph-2023-000702.Peer-Reviewed Original ResearchDiabetes prevention education programControl armIntervention armEducational sessionsMean differencePrevention education programPostintervention assessmentsLifestyle intervention programLifestyle intervention studyTRIAL REGISTRATION NUMBERTwo-arm clusterSecondary outcomesDiabetes preventionMiddle-income countriesPrimary outcomeTreat analysisWaist circumferenceMonths interventionPhysical activityRegistration numberGrain intakeIntervention studiesBaseline measuresSignificant weight reductionIntervention programs
2021
White matter changes in psychosis risk relate to development and are not impacted by the transition to psychosis
Di Biase MA, Cetin-Karayumak S, Lyall AE, Zalesky A, Cho KIK, Zhang F, Kubicki M, Rathi Y, Lyons MG, Bouix S, Billah T, Anticevic A, Schleifer C, Adkinson BD, Ji JL, Tamayo Z, Addington J, Bearden CE, Cornblatt BA, Keshavan MS, Mathalon DH, McGlashan TH, Perkins DO, Cadenhead KS, Tsuang MT, Woods SW, Stone WS, Shenton ME, Cannon TD, Pasternak O. White matter changes in psychosis risk relate to development and are not impacted by the transition to psychosis. Molecular Psychiatry 2021, 26: 6833-6844. PMID: 34024906, PMCID: PMC8611104, DOI: 10.1038/s41380-021-01128-8.Peer-Reviewed Original ResearchConceptsClinical high riskWhite matter changesWhite matter microstructureHigh riskMatter changesCHR individualsAge-related white matter changesNorth American Prodrome Longitudinal StudyEmergence of psychosisWhite matter abnormalitiesYears of ageImpact of ageIllness onsetExtracellular free waterHealthy controlsLongitudinal cohortCHR subjectsMagnetic resonance imaging dataProspective analysisRegional fatLinear mixed effects modelsHigh fatPsychosisFractional anisotropyBaseline measures
2019
Does Maternal Reflective Functioning Mediate Associations Between Representations of Caregiving With Maternal Sensitivity in a High-Risk Sample?
Alvarez-Monjarás M, McMahon TJ, Suchman NE. Does Maternal Reflective Functioning Mediate Associations Between Representations of Caregiving With Maternal Sensitivity in a High-Risk Sample? Psychoanalytic Psychology 2019, 36: 82-92. PMID: 30853749, PMCID: PMC6404967, DOI: 10.1037/pap0000166.Peer-Reviewed Original ResearchMaternal sensitivityReflective functioningMental representationsAttachment-based interventionsHigh-risk sampleSubstance-abusing mothersSubstance abuse disordersAttachment perspectivePositive parentingAdequate parentingDiverse sampleMediate associationsAbuse disordersBaseline measuresFunctioningParentingSecondary data analysisCaregivingSignificant relationshipAlternate explanationRepresentationMothersToddlersRelationshipChildren
2017
Trajectories of posttraumatic growth among US military veterans: a 4‐year nationally representative, prospective cohort study
Tsai J, Pietrzak RH. Trajectories of posttraumatic growth among US military veterans: a 4‐year nationally representative, prospective cohort study. Acta Psychiatrica Scandinavica 2017, 136: 483-492. PMID: 28846800, DOI: 10.1111/acps.12800.Peer-Reviewed Original ResearchConceptsProspective cohort studyPTG trajectoriesUS military veteransCertain psychosocial factorsPosttraumatic stress disorder (PTSD) symptomsCohort studyUS veteransPsychosocial factorsGreater severityPosttraumatic growthPsychosocial variablesPredominant trajectoriesBaseline measuresDisorder symptomsMilitary veteransModerate posttraumatic growthAvoidance symptomsSymptomsSocial supportLatent growth mixtureVeteransRepresentative surveyGrowth mixture
2015
HIV testing service awareness and service uptake among female heads of household in rural Mozambique: results from a province-wide survey
Paulin HN, Blevins M, Koethe JR, Hinton N, Vaz L, Vergara AE, Mukolo A, Ndatimana E, Moon TD, Vermund SH, Wester CW. HIV testing service awareness and service uptake among female heads of household in rural Mozambique: results from a province-wide survey. BMC Public Health 2015, 15: 132. PMID: 25881182, PMCID: PMC4339241, DOI: 10.1186/s12889-015-1388-z.Peer-Reviewed Original ResearchConceptsHealth service accessService uptakeVCT servicesRural Zambézia ProvinceHigh HIV prevalencePopulation-based surveyRemote rural settingsConclusionsMost womenRural MozambiqueHigh HIVVoluntary counselingTwo-stage cluster sampleHIV prevalenceProvince-wide surveyService accessHIV stigmaHealth facilitiesZambézia ProvinceStigma scoresTesting utilizationStigma reductionLogistic regressionBaseline measuresSurvey domainsVCT
2014
Can We Improve Cognitive–Behavioral Therapy for Chronic Back Pain Treatment Engagement and Adherence? A Controlled Trial of Tailored Versus Standard Therapy
Kerns RD, Burns JW, Shulman M, Jensen MP, Nielson WR, Czlapinski R, Dallas MI, Chatkoff D, Sellinger J, Heapy A, Rosenberger P. Can We Improve Cognitive–Behavioral Therapy for Chronic Back Pain Treatment Engagement and Adherence? A Controlled Trial of Tailored Versus Standard Therapy. Health Psychology 2014, 33: 938-947. PMID: 24295024, DOI: 10.1037/a0034406.Peer-Reviewed Original ResearchConceptsStandard CBTMotivational enhancement strategiesTreatment engagementSkills practiceCognitive behavioral therapyIndex of engagementBehavioral therapyBehavioral skillsGoal accomplishmentLow dropout ratePosttreatment improvementTreatment participationDaily ratingsOutcomes supportTherapeutic processBaseline measuresEnhancement strategiesMore sessionsParticipants' preferencesChronic back painTCBTParticipantsEngagementOutcome factorsTreatment conditionsReturn of individual genetic results in a high-risk sample: enthusiasm and positive behavioral change
Hartz SM, Olfson E, Culverhouse R, Cavazos-Rehg P, Chen LS, DuBois J, Fisher S, Kaphingst K, Kaufman D, Plunk A, Ramnarine S, Solomon S, Saccone NL, Bierut LJ. Return of individual genetic results in a high-risk sample: enthusiasm and positive behavioral change. Genetics In Medicine 2014, 17: 374-379. PMID: 25166427, PMCID: PMC4344933, DOI: 10.1038/gim.2014.110.Peer-Reviewed Original ResearchConceptsHigh riskPathway GenomicsBaseline measuresAdequate health literacyMultiple risk factorsSymptoms of depressionPercent of participantsHigh baseline measuresAdverse psychological reactionsIncreased riskRisk factorsHigh-risk sampleCessation attemptsGenetic resultsHealth literacyNicotine dependenceUnderserved populationsPositive behavioral changesGenetic riskHealth insuranceDepressionAfrican AmericansLower ratesRiskBehavioral changes
2012
Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies
Voos AC, Pelphrey KA, Tirrell J, Bolling DZ, Wyk B, Kaiser MD, McPartland JC, Volkmar FR, Ventola P. Neural Mechanisms of Improvements in Social Motivation After Pivotal Response Treatment: Two Case Studies. Journal Of Autism And Developmental Disorders 2012, 43: 1-10. PMID: 23104615, PMCID: PMC4999079, DOI: 10.1007/s10803-012-1683-9.Peer-Reviewed Original ResearchConceptsPivotal Response TreatmentAutism spectrum disorderSocial stimuliResponse treatmentFunctional magnetic resonance imagingYoung childrenNeural correlatesSocial motivationSocial skillsSocial perceptionNeural mechanismsNeural responsesBehavioral measuresSpectrum disorderSocial communicationBehavioral treatmentEye trackingNeural systemsAdaptive behaviorBrain regionsBaseline measuresStriking gainsStimuliChildrenPositive effectProspective Analysis of Early Lapse to Drinking and Smoking Among Individuals in Concurrent Alcohol and Tobacco Treatment
Holt LJ, Litt MD, Cooney NL. Prospective Analysis of Early Lapse to Drinking and Smoking Among Individuals in Concurrent Alcohol and Tobacco Treatment. Psychology Of Addictive Behaviors 2012, 26: 561-572. PMID: 22023022, PMCID: PMC3336035, DOI: 10.1037/a0026039.Peer-Reviewed Original ResearchConceptsConcurrent alcoholPositive moodSmoking treatmentSmoking lapseLower positive moodEcological momentary assessment methodsOutpatient substance abuse clinicsMomentary assessment methodsQuantity/frequencyNegative affectLow confidenceEMA measuresAffective statesEMA ratingsHigher urgeTobacco treatmentSmoking urgesEarly lapseInitial lapseSubstance abuse clinicsLapse riskNicotine withdrawalBaseline measuresInitial smokingCurrent studyDoes Housing Chronically Homeless Adults Lead to Social Integration?
Tsai J, Mares AS, Rosenheck RA. Does Housing Chronically Homeless Adults Lead to Social Integration? Psychiatric Services 2012, 63: 427-434. PMID: 22549528, DOI: 10.1176/appi.ps.201100047.Peer-Reviewed Original Research
2011
Religiosity Among Adults Who Are Chronically Homeless: Association With Clinical and Psychosocial Outcomes
Tsai J, Rosenheck RA. Religiosity Among Adults Who Are Chronically Homeless: Association With Clinical and Psychosocial Outcomes. Psychiatric Services 2011, 62: 1222-1224. PMID: 21969651, DOI: 10.1176/ps.62.10.pss6210_1222.Peer-Reviewed Original ResearchThe antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [1H]-MRS
Valentine GW, Mason GF, Gomez R, Fasula M, Watzl J, Pittman B, Krystal JH, Sanacora G. The antidepressant effect of ketamine is not associated with changes in occipital amino acid neurotransmitter content as measured by [1H]-MRS. Psychiatry Research 2011, 191: 122-127. PMID: 21232924, PMCID: PMC3061550, DOI: 10.1016/j.pscychresns.2010.10.009.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAntidepressive AgentsBlood PressureDepressive Disorder, MajorDissociative DisordersFemalegamma-Aminobutyric AcidGlutamic AcidHeart RateHumansKetamineMagnetic Resonance SpectroscopyMaleMiddle AgedOccipital LobeProtonsPsychiatric Status Rating ScalesPsychometricsRetrospective StudiesSingle-Blind MethodStatistics as TopicTime FactorsYoung AdultConceptsMajor depressive disorderAntidepressant effectsAntidepressant actionNeurotransmitter contentNMDA receptor antagonist ketamineProton magnetic resonance spectroscopy methodConventional antidepressant treatmentKetamine's antidepressant actionSingle intravenous doseSingle-blind conditionsAntidepressant treatmentChronic treatmentKetamine infusionIntravenous dosePharmacodynamic basisDepressive disorderAcute actionsMRS scansOccipital cortexDepressive symptomsDepression scoresRating ScaleBaseline measuresInfusionKetamine
2010
Sleep Disturbances and Adverse Driving Events in a Predominantly Male Cohort of Active Older Drivers
Fragoso C, Araujo KL, Van Ness PH, Marottoli RA. Sleep Disturbances and Adverse Driving Events in a Predominantly Male Cohort of Active Older Drivers. Journal Of The American Geriatrics Society 2010, 58: 1878-1884. PMID: 20929465, PMCID: PMC2954505, DOI: 10.1111/j.1532-5415.2010.03083.x.Peer-Reviewed Original ResearchConceptsHigh sleep apnea riskAdverse driving eventsSleep apnea riskSleep disturbancesApnea riskDaytime drowsinessMale cohortOlder personsAdjusted multivariable modelGreater New HavenActive older driversPrimary outcomeOlder DriversSleep QuestionnaireMultivariable modelMedian scoreBaseline measuresCommunity sitesInsomniaCohortDrowsinessFuture studiesRiskNew HavenDays
2008
The feasibility of online genetic testing for lung cancer susceptibility: uptake of a web-based protocol and decision outcomes
O'Neill S, White D, Sanderson SC, Lipkus IM, Bepler G, Bastian LA, McBride CM. The feasibility of online genetic testing for lung cancer susceptibility: uptake of a web-based protocol and decision outcomes. Genetics In Medicine 2008, 10: 121-130. PMID: 18281920, DOI: 10.1097/gim.0b013e31815f8e06.Peer-Reviewed Original ResearchConceptsGenetic susceptibility testingLung cancerStudy websiteGenetic testingSusceptibility testingLung cancer susceptibilityCancer genetic testingEligible relativesBaseline interviewQuit motivationBaseline measuresBlood relativesWeb-based protocolCancer susceptibilityTelephone surveyOutcomesInformed decisionsCancer
2004
Test–retest stability of neuropsychological testing and individual differences in variability in schizophrenia outpatients
Greig T, Nicholls SS, Wexler BE, Bell MD. Test–retest stability of neuropsychological testing and individual differences in variability in schizophrenia outpatients. Psychiatry Research 2004, 129: 241-247. PMID: 15661317, DOI: 10.1016/j.psychres.2004.09.006.Peer-Reviewed Original ResearchConceptsNeurocognitive functionImpact of treatmentTest-retest variabilityClinical trialsNeuropsychological testingStable outpatientsSchizoaffective disorderMeasures of psychopathologyTest-retest changesMost subjectsSchizophrenia outpatientsBaseline measuresNeuropsychological testsSchizophrenia researchTest-retest stabilityOutpatientsReliable instrumentSignificant changesTreatmentSubject variancePractice effectsSubjectsPatientsNeuropathology
2002
Longitudinal Benefit of Positive Self-Perceptions of Aging on Functional Health
Levy BR, Slade MD, Kasl SV. Longitudinal Benefit of Positive Self-Perceptions of Aging on Functional Health. The Journals Of Gerontology Series B 2002, 57: p409-p417. PMID: 12198099, DOI: 10.1093/geronb/57.5.p409.Peer-Reviewed Original Research
2000
Disulfiram versus placebo for cocaine dependence in buprenorphine-maintained subjects: a preliminary trial
George T, Chawarski M, Pakes J, Carroll K, Kosten T, Schottenfeld R. Disulfiram versus placebo for cocaine dependence in buprenorphine-maintained subjects: a preliminary trial. Biological Psychiatry 2000, 47: 1080-1086. PMID: 10862808, DOI: 10.1016/s0006-3223(99)00310-8.Peer-Reviewed Original ResearchConceptsBuprenorphine-maintained subjectsCocaine dependenceUrine testsBuprenorphine-maintained patientsEffect of disulfiramContinuous cocaine abstinenceCocaine-dependent subjectsDrug use severityBuprenorphine maintenancePlacebo treatmentDisulfiram groupPlaceboCocaine abstinencePotential efficacyDependent subjectsBaseline measuresDisulfiramNumber of daysWeeksHigh rateSubjectsTrialsPreliminary trialTreatmentPreliminary study
1996
Noradrenergic mechanisms in stress and anxiety: II. Clinical studies
Bremner J, Krystal J, Southwick S, Charney D. Noradrenergic mechanisms in stress and anxiety: II. Clinical studies. Synapse 1996, 23: 39-51. PMID: 8723134, DOI: 10.1002/(sici)1098-2396(199605)23:1<39::aid-syn5>3.0.co;2-i.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderBlood pressureNoradrenergic functionHeart rateNoradrenergic systemClinical studiesAdrenergic receptorsPanic disorderAnxiety disordersGrowth hormone responseMeasurement of norepinephrineNorepinephrine responseNoradrenergic mechanismsBaseline norepinephrineNoradrenergic responsivenessPharmacological challengeCatecholaminergic functionHormone responseTraumatic remindersPatientsAcute stressorStress disorderNorepinephrineBaseline measuresConsistent finding
1990
Treatment of an adolescent with obsessive-compulsive disorder by alternating response prevention and cognitive therapy: An empirical analysis
Kearney C, Silverman W. Treatment of an adolescent with obsessive-compulsive disorder by alternating response prevention and cognitive therapy: An empirical analysis. Journal Of Behavior Therapy And Experimental Psychiatry 1990, 21: 39-47. PMID: 2373767, DOI: 10.1016/0005-7916(90)90047-o.Peer-Reviewed Original ResearchConceptsCognitive therapyObsessive-compulsive disorderResponse preventionCompulsive behaviorsSelf-reported anxietyObsessive-compulsive behaviorSevere obsessive-compulsive disorderParental ratingsClient ratingsAnxietyBaseline measuresPersonal discomfortRatingsDepressionDisordersAdolescentsBehaviorParentsSessionsBoysFrequency levelsMeasuresSignificant influence
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