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Wedding Rigorous Scientific Methodology and Ancient Herbal Wisdom to Benefit Cancer Patients: The Development of PHY906
Our own studies of traditional Chinese medicine began in the early 2000s, when we sought to answer the question of whether there was a Chinese herbal medicine that could prevent and/or reduce the gastrointestinal toxicities associated with irinotecan-based chemotherapy. Around that time, the combination of irinotecan, fluorouracil (5-FU), and leucovorin (IFL) was being developed as a frontline treatment regimen, and it was associated with a 25% to 30% incidence of grade 3 or 4 gastrointestinal toxicity. With this in mind, Professor Yung-Chi Cheng, PhD, and his research team at Yale University reviewed the Chinese literature and identified Huang Qin Tang as a classic formula that has been widely used in China and other Asian countries to treat gastrointestinal disorders.
Source: Cancer Network