2024
Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University
Würstle S, Lee A, Kortright K, Winzig F, An W, Stanley G, Rajagopalan G, Harris Z, Sun Y, Hu B, Blazanin M, Hajfathalian M, Bollyky P, Turner P, Koff J, Chan B. Optimized preparation pipeline for emergency phage therapy against Pseudomonas aeruginosa at Yale University. Scientific Reports 2024, 14: 2657. PMID: 38302552, PMCID: PMC10834462, DOI: 10.1038/s41598-024-52192-3.Peer-Reviewed Original ResearchConceptsEvolutionary selection pressurePhage characterizationPhage therapyPersistent bacterial infectionsBacteriophage therapyPhageSelection pressurePseudomonas aeruginosaInvestigational new drug applicationBacterial infectionsNew Drug ApplicationTherapyDrug applicationClinical applicationAutographiviridaeBacteriaPotential strategy
2021
Community context matters for bacteria-phage ecology and evolution
Blazanin M, Turner P. Community context matters for bacteria-phage ecology and evolution. The ISME Journal: Multidisciplinary Journal Of Microbial Ecology 2021, 15: 3119-3128. PMID: 34127803, PMCID: PMC8528888, DOI: 10.1038/s41396-021-01012-x.Peer-Reviewed Original ResearchConceptsBacteria-phage systemsEvolutionary effectsBacteria-phage coevolutionValuable biological modelUnderstanding of bacteriaAdditional bacterial speciesMechanisms of adaptationEcological interactionsPleiotropic consequencesComplex communitiesCoevolutionary dynamicsBacterial speciesEcologyPhagesBacteriaBiological modelsSymbiosesCoevolutionCommunity contextSpeciesEvolutionMultispeciesCommunityAdaptationCommunity presence
2009
Bacteriophage Ecology
Abedon S, Duffy S, Turner P. Bacteriophage Ecology. 2009, 42-57. DOI: 10.1016/b978-012373944-5.00022-5.Peer-Reviewed Original ResearchPhage ecologyEcosystem ecologyNutrient cyclingCommunity ecologyAbiotic componentsTerrestrial environmentsPopulation ecologyEcologyBacteriophage ecologyBiological populationsEnvironmental microbiologyPhage interactionsEnergy flowHost bacteriaPhagesBacteriaHabitatsEcologistsCyclingEukaryotesCommunityBacteriophagesImpactInteractionEnvironment