Michael Murrell
Associate Professor Tenure
Research & Publications
Biography
News
Coauthors
Selected Publications
- Confinement induces internal flows in adherent cell aggregatesYousafzai M, Amiri S, Sun Z, Pahlavan , Murrell M. Confinement induces internal flows in adherent cell aggregates. Journal Of The Royal Society Interface 2024, 21: 20240105. PMID: 38774959, DOI: 10.1098/rsif.2024.0105.
- Growth‐induced collective bending and kinetic trapping of cytoskeletal filamentsBanerjee D, Freedman S, Murrell M, Banerjee S. Growth‐induced collective bending and kinetic trapping of cytoskeletal filaments. Cytoskeleton 2024 PMID: 38775207, DOI: 10.1002/cm.21877.
- Elastocapillary effects determine early matrix deformation by glioblastoma cell spheroidsAng I, Yousafzai M, Yadav V, Mohler K, Rinehart J, Bouklas N, Murrell M. Elastocapillary effects determine early matrix deformation by glioblastoma cell spheroids. APL Bioengineering 2024, 8: 026109. PMID: 38706957, PMCID: PMC11069407, DOI: 10.1063/5.0191765.
- F-actin architecture determines the conversion of chemical energy into mechanical workSakamoto R, Murrell M. F-actin architecture determines the conversion of chemical energy into mechanical work. Nature Communications 2024, 15: 3444. PMID: 38658549, PMCID: PMC11043346, DOI: 10.1038/s41467-024-47593-x.
- Cofilin-mediated actin filament network flexibility facilitates 2D to 3D actomyosin shape changeSun Z, Yadav V, Amiri S, Cao W, De La Cruz E, Murrell M. Cofilin-mediated actin filament network flexibility facilitates 2D to 3D actomyosin shape change. European Journal Of Cell Biology 2023, 103: 151379. PMID: 38168598, DOI: 10.1016/j.ejcb.2023.151379.
- Actin and Microtubules Position Stress GranulesBöddeker T, Rusch A, Leeners K, Murrell M, Dufresne E. Actin and Microtubules Position Stress Granules. PRX Life 2023, 1: 023010. DOI: 10.1103/prxlife.1.023010.
- Author Correction: Membrane tension induces F-actin reorganization and flow in a biomimetic model cortexSakamoto R, Banerjee D, Yadav V, Chen S, Gardel M, Sykes C, Banerjee S, Murrell M. Author Correction: Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex. Communications Biology 2023, 6: 470. PMID: 37117264, PMCID: PMC10147711, DOI: 10.1038/s42003-023-04818-x.
- Membrane tension induces F-actin reorganization and flow in a biomimetic model cortexSakamoto R, Banerjee D, Yadav V, Chen S, Gardel M, Sykes C, Banerjee S, Murrell M. Membrane tension induces F-actin reorganization and flow in a biomimetic model cortex. Communications Biology 2023, 6: 325. PMID: 36973388, PMCID: PMC10043271, DOI: 10.1038/s42003-023-04684-7.
- Author Correction: Dysregulation of TSP2-Rac1-WAVE2 axis in diabetic cells leads to cytoskeletal disorganization, increased cell stiffness, and dysfunctionXing H, Huang Y, Kunkemoeller B, Dahl P, Muraleetharan O, Malvankar N, Murrell M, Kyriakides T. Author Correction: Dysregulation of TSP2-Rac1-WAVE2 axis in diabetic cells leads to cytoskeletal disorganization, increased cell stiffness, and dysfunction. Scientific Reports 2023, 13: 4253. PMID: 36918662, PMCID: PMC10015071, DOI: 10.1038/s41598-023-31191-w.
- F-actin architectures differentially constrain myosin thick filament motionMuresan C, Sun Z, Yadav V, Tabatabai A, Lanier L, Kim J, Kim T, Murrell M. F-actin architectures differentially constrain myosin thick filament motion. Biophysical Journal 2023, 122: 294a. DOI: 10.1016/j.bpj.2022.11.1662.
- Dysregulation of TSP2-Rac1-WAVE2 axis in diabetic cells leads to cytoskeletal disorganization, increased cell stiffness, and dysfunctionXing H, Huang Y, Kunkemoeller B, Dahl P, Muraleetharan O, Malvankar N, Murrell M, Kyriakides T. Dysregulation of TSP2-Rac1-WAVE2 axis in diabetic cells leads to cytoskeletal disorganization, increased cell stiffness, and dysfunction. Scientific Reports 2022, 12: 22474. PMID: 36577792, PMCID: PMC9797577, DOI: 10.1038/s41598-022-26337-1.
- F-actin architecture determines constraints on myosin thick filament motionMuresan C, Sun Z, Yadav V, Tabatabai A, Lanier L, Kim J, Kim T, Murrell M. F-actin architecture determines constraints on myosin thick filament motion. Nature Communications 2022, 13: 7008. PMID: 36385016, PMCID: PMC9669029, DOI: 10.1038/s41467-022-34715-6.
- Interplay between substrate rigidity and tissue fluidity regulates cell monolayer spreadingStaddon M, Murrell M, Banerjee S. Interplay between substrate rigidity and tissue fluidity regulates cell monolayer spreading. Soft Matter 2022, 18: 7877-7886. PMID: 36205535, PMCID: PMC9700261, DOI: 10.1039/d2sm00757f.
- In Vitro Reconstitution of the Actin Cytoskeleton Inside Giant Unilamellar Vesicles.Chen S, Sun Z, Murrell M. In Vitro Reconstitution of the Actin Cytoskeleton Inside Giant Unilamellar Vesicles. Journal Of Visualized Experiments 2022 PMID: 36094272, DOI: 10.3791/64026.
- Cell-Matrix Elastocapillary Interactions Drive Pressure-Based Wetting of Cell AggregatesYousafzai M, Yadav V, Amiri S, Staddon M, Errami Y, Jaspard G, Banerjee S, Murrell M. Cell-Matrix Elastocapillary Interactions Drive Pressure-Based Wetting of Cell Aggregates. Physical Review X 2022, 12: 031027. PMID: 38009085, PMCID: PMC10673637, DOI: 10.1103/physrevx.12.031027.
- A molecular clock controls periodically driven cell migration in confined spacesLee SH, Hou JC, Hamidzadeh A, Yousafzai MS, Ajeti V, Chang H, Odde DJ, Murrell M, Levchenko A. A molecular clock controls periodically driven cell migration in confined spaces. Cell Systems 2022, 13: 514-529.e10. PMID: 35679858, DOI: 10.1016/j.cels.2022.05.005.
- Correction: The structural, vibrational, and mechanical properties of jammed packings of deformable particles in three dimensionsWang D, Treado JD, Boromand A, Norwick B, Murrell MP, Shattuck MD, O'Hern CS. Correction: The structural, vibrational, and mechanical properties of jammed packings of deformable particles in three dimensions. Soft Matter 2022, 18: 3815-3815. PMID: 35506750, PMCID: PMC9116153, DOI: 10.1039/d2sm90054h.
- Erratum: Bridging particle deformability and collective response in soft solids [Phys. Rev. Materials 5, 055605 (2021)]Treado J, Wang D, Boromand A, Murrell M, Shattuck M, O'Hern C. Erratum: Bridging particle deformability and collective response in soft solids [Phys. Rev. Materials 5, 055605 (2021)]. Physical Review Materials 2022, 6: 059901. DOI: 10.1103/physrevmaterials.6.059901.
- Gradients in solid surface tension drive Marangoni-like motions in cell aggregatesYadav V, Yousafzai S, Amiri S, Style R, Dufresne E, Murrell M. Gradients in solid surface tension drive Marangoni-like motions in cell aggregates. Physical Review Fluids 2022, 7: l031101. DOI: 10.1103/physrevfluids.7.l031101.
- Active Regulation of Pressure and Volume Defines an Energetic Constraint on the Size of Cell AggregatesYousafzai M, Yadav V, Amiri S, Errami Y, Amiri S, Murrell M. Active Regulation of Pressure and Volume Defines an Energetic Constraint on the Size of Cell Aggregates. Physical Review Letters 2022, 128: 048103. PMID: 35148133, DOI: 10.1103/physrevlett.128.048103.
- Bridging particle deformability and collective response in soft solidsTreado J, Wang D, Boromand A, Murrell M, Shattuck M, O'Hern C. Bridging particle deformability and collective response in soft solids. Physical Review Materials 2021, 5: 055605. DOI: 10.1103/physrevmaterials.5.055605.
- Filament Nucleation Tunes Mechanical Memory in Active Polymer NetworksYadav V, Banerjee D, Tabatabai A, Kovar D, Kim T, Banerjee S, Murrell M. Filament Nucleation Tunes Mechanical Memory in Active Polymer Networks. Advanced Functional Materials 2019, 29 PMID: 32523502, PMCID: PMC7286550, DOI: 10.1002/adfm.201905243.
- A Dynamic Time Step Method in Cytoskeletal SimulationsTibbs J, Tabatabai A, Seara D, Tabei A, Murrell M. A Dynamic Time Step Method in Cytoskeletal Simulations. Biophysical Journal 2019, 116: 251a. DOI: 10.1016/j.bpj.2018.11.1370.
- Work and Dissipation in the Cell CytoskeletonMurrell M, Banerjee S, Ajeti V, Tabatabai P, Fleszar A, Staddon M, Seara D, Suarez C, Muhammad S, Bi D, Kovar D. Work and Dissipation in the Cell Cytoskeleton. Biophysical Journal 2019, 116: 3a. DOI: 10.1016/j.bpj.2018.11.040.
- F‑Actin Fragmentation Induces Distinct Mechanisms of Stress Relaxation in the Actin CytoskeletonJung W, Murrell M, Kim T. F‑Actin Fragmentation Induces Distinct Mechanisms of Stress Relaxation in the Actin Cytoskeleton. ACS Macro Letters 2016, 5: 641-645. PMID: 35614663, DOI: 10.1021/acsmacrolett.6b00232.
- F-Actin Fragmentation Induces Distinct Mechanisms of Stress Relaxation in the Actin CytoskeletonJung W, Murrell M, Kim T. F-Actin Fragmentation Induces Distinct Mechanisms of Stress Relaxation in the Actin Cytoskeleton. Biophysical Journal 2016, 110: 354a. DOI: 10.1016/j.bpj.2015.11.1911.
- High‐content imaging with micropatterned multiwell plates reveals influence of cell geometry and cytoskeleton on chromatin dynamicsHarkness T, McNulty J, Prestil R, Seymour S, Klann T, Murrell M, Ashton R, Saha K. High‐content imaging with micropatterned multiwell plates reveals influence of cell geometry and cytoskeleton on chromatin dynamics. Biotechnology Journal 2015, 10: 1555-1567. PMID: 26097126, PMCID: PMC6948850, DOI: 10.1002/biot.201400756.
- F-actin cross-linking enhances the stability of force generation in disordered actomyosin networksJung W, Murrell M, Kim T. F-actin cross-linking enhances the stability of force generation in disordered actomyosin networks. Computational Particle Mechanics 2015, 2: 317-327. DOI: 10.1007/s40571-015-0052-9.
- Liposome Adhesion Generates Contractile Traction StressesMurrell M, Voituriez R, Joanny J, Nassoy P, Sykes C, Gardel M. Liposome Adhesion Generates Contractile Traction Stresses. Biophysical Journal 2015, 108: 181a-182a. DOI: 10.1016/j.bpj.2014.11.1003.
- How cells flow in the spreading of cellular aggregatesBeaune G, Stirbat T, Khalifat N, Cochet-Escartin O, Garcia S, Gurchenkov V, Murrell M, Dufour S, Cuvelier D, Brochard-Wyart F. How cells flow in the spreading of cellular aggregates. Proceedings Of The National Academy Of Sciences Of The United States Of America 2014, 111: 8055-8060. PMID: 24835175, PMCID: PMC4050549, DOI: 10.1073/pnas.1323788111.
- Actomyosin sliding is attenuated in contractile biomimetic corticesMurrell M, Gardel M. Actomyosin sliding is attenuated in contractile biomimetic cortices. Molecular Biology Of The Cell 2014, 25: 1845-1853. PMID: 24760970, PMCID: PMC4055264, DOI: 10.1091/mbc.e13-08-0450.
- Liposome adhesion generates traction stressMurrell M, Voituriez R, Joanny J, Nassoy P, Sykes C, Gardel M. Liposome adhesion generates traction stress. Nature Physics 2014, 10: 163-169. DOI: 10.1038/nphys2855.
- Chapter Fifteen Reconstitution of Contractile Actomyosin ArraysMurrell M, Thoresen T, Gardel M. Chapter Fifteen Reconstitution of Contractile Actomyosin Arrays. 2014, 540: 265-282. PMID: 24630112, PMCID: PMC4459579, DOI: 10.1016/b978-0-12-397924-7.00015-7.
- Distribution of directional change as a signature of complex dynamicsBurov S, Tabei S, Huynh T, Murrell M, Philipson L, Rice S, Gardel M, Scherer N, Dinner A. Distribution of directional change as a signature of complex dynamics. Proceedings Of The National Academy Of Sciences Of The United States Of America 2013, 110: 19689-19694. PMID: 24248363, PMCID: PMC3856831, DOI: 10.1073/pnas.1319473110.
- F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortexMurrell M, Gardel M. F-actin buckling coordinates contractility and severing in a biomimetic actomyosin cortex. Proceedings Of The National Academy Of Sciences Of The United States Of America 2012, 109: 20820-20825. PMID: 23213249, PMCID: PMC3529094, DOI: 10.1073/pnas.1214753109.
- Force Transmission in a Reconstituted Actomyosin CortexMurrell M, Sykes C, Gardel M. Force Transmission in a Reconstituted Actomyosin Cortex. Biophysical Journal 2012, 102: 238a-239a. DOI: 10.1016/j.bpj.2011.11.1313.
- Spreading Dynamics of Biomimetic Actin CorticesMurrell M, Pontani L, Guevorkian K, Cuvelier D, Nassoy P, Sykes C. Spreading Dynamics of Biomimetic Actin Cortices. Biophysical Journal 2011, 100: 1400-1409. PMID: 21402021, PMCID: PMC3059579, DOI: 10.1016/j.bpj.2011.01.038.
- Negative Autoregulation by FAS Mediates Robust Fetal ErythropoiesisSocolovsky M, Murrell M, Liu Y, Pop R, Porpiglia E, Levchenko A. Negative Autoregulation by FAS Mediates Robust Fetal Erythropoiesis. PLOS Biology 2007, 5: e252. PMID: 17896863, PMCID: PMC1988857, DOI: 10.1371/journal.pbio.0050252.
- Computational Modeling in GlycosylationMurrell M, Yarema K, Levchenko A. Computational Modeling in Glycosylation. 2005, 247-288. DOI: 10.1201/9781420027631.ch8.
- The Systems Biology of GlycosylationMurrell M, Yarema K, Levchenko A. The Systems Biology of Glycosylation. ChemInform 2004, 35: no-no. DOI: 10.1002/chin.200449270.
- The Systems Biology of GlycosylationMurrell M, Yarema K, Levchenko A. The Systems Biology of Glycosylation. ChemBioChem 2004, 5: 1334-1347. PMID: 15457533, DOI: 10.1002/cbic.200400143.