Taylor Takasugi
he/him/his
Hospital ResidentAbout
Research
Publications
2025
Low vacuum (3 mL) rapid serum tubes offer better protection from hemolysis than plasma separator tubes collected in the emergency department
Shang E, Takasugi T, Prellwitz P, Figueroa Villalba C, Sangal R, Venkatesh A, Maciejak L, Oberle E, El-Khoury J. Low vacuum (3 mL) rapid serum tubes offer better protection from hemolysis than plasma separator tubes collected in the emergency department. Clinical Biochemistry 2025, 139: 110984. PMID: 40721040, DOI: 10.1016/j.clinbiochem.2025.110984.Peer-Reviewed Original Research
2023
Pot1b −/− tumors activate G-quadruplex-induced DNA damage to promote telomere hyper-elongation
Takasugi T, Gu P, Liang F, Staco I, Chang S. Pot1b −/− tumors activate G-quadruplex-induced DNA damage to promote telomere hyper-elongation. Nucleic Acids Research 2023, 51: 9227-9247. PMID: 37560909, PMCID: PMC10516629, DOI: 10.1093/nar/gkad648.Peer-Reviewed Original Research
2021
Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres
Gu P, Jia S, Takasugi T, Tesmer VM, Nandakumar J, Chen Y, Chang S. Distinct functions of POT1 proteins contribute to the regulation of telomerase recruitment to telomeres. Nature Communications 2021, 12: 5514. PMID: 34535663, PMCID: PMC8448735, DOI: 10.1038/s41467-021-25799-7.Peer-Reviewed Original Research
2019
Absence of XRCC4 and its paralogs in human cells reveal differences in outcomes for DNA repair and V(D)J recombination
Ruis B, Molan A, Takasugi T, Hendrickson E. Absence of XRCC4 and its paralogs in human cells reveal differences in outcomes for DNA repair and V(D)J recombination. DNA Repair 2019, 85: 102738. PMID: 31731258, PMCID: PMC6952554, DOI: 10.1016/j.dnarep.2019.102738.Peer-Reviewed Original Research
2018
CTC1‐STN1 coordinates G‐ and C‐strand synthesis to regulate telomere length
Gu P, Jia S, Takasugi T, Smith E, Nandakumar J, Hendrickson E, Chang S. CTC1‐STN1 coordinates G‐ and C‐strand synthesis to regulate telomere length. Aging Cell 2018, 17: e12783. PMID: 29774655, PMCID: PMC6052479, DOI: 10.1111/acel.12783.Peer-Reviewed Original Research
2017
Mechanisms of precise genome editing using oligonucleotide donors
Kan Y, Ruis B, Takasugi T, Hendrickson E. Mechanisms of precise genome editing using oligonucleotide donors. Genome Research 2017, 27: 1099-1111. PMID: 28356322, PMCID: PMC5495063, DOI: 10.1101/gr.214775.116.Peer-Reviewed Original Research
2016
Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4
Liddiard K, Ruis B, Takasugi T, Harvey A, Ashelford K, Hendrickson E, Baird D. Sister chromatid telomere fusions, but not NHEJ-mediated inter-chromosomal telomere fusions, occur independently of DNA ligases 3 and 4. Genome Research 2016, 26: 588-600. PMID: 26941250, PMCID: PMC4864465, DOI: 10.1101/gr.200840.115.Peer-Reviewed Original Research