Shanae Aerts
Research
Publications
2025
Heparins Enhance C1 Esterase Inhibitor Activity: A Promising Remedy for Acute Hereditary Angioedema
Chan E, Zhou Y, Hor L, Buckle A, Majluf-Cruz A, Dennis J, Woroch E, Hellbusch B, Archuleta E, Fornis L, Garcia C, Aerts S, Bai X, Bevers S, Schmidt E, Bates M, Fugit R, Nieto-Martinez S, Galvan M, Giclas P, Frazer-Abel A. Heparins Enhance C1 Esterase Inhibitor Activity: A Promising Remedy for Acute Hereditary Angioedema. American Journal Of Respiratory And Critical Care Medicine 2025, 211: a3798-a3798. DOI: 10.1164/ajrccm.2025.211.abstracts.a3798.Peer-Reviewed Original Research
2019
Comparing the Ability of Unfractionated Heparin, Enoxaparin, and Nadroparin to Augment C1 Esterase Inhibitor Activity in Sera of Patients with Hereditary Angioedema
Chan E, Dennis J, Woroch E, Hellbusch B, Shaun B, Schmidt E, Aerts S, Bates M, Fugit R, Nieto-Martinez S, Majluf-Cruz A, Giclas P, Frazer-Abel A, Zhou Y. Comparing the Ability of Unfractionated Heparin, Enoxaparin, and Nadroparin to Augment C1 Esterase Inhibitor Activity in Sera of Patients with Hereditary Angioedema. 2019, a2975-a2975. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2975.Peer-Reviewed Original ResearchThe Role of Cigarette Smoke-Exposed T Regulatory Cells in Macrophage Control of Mycobacterium Tuberculosis
Chan E, Aerts S, Musheyev A, Honda J, Bai X. The Role of Cigarette Smoke-Exposed T Regulatory Cells in Macrophage Control of Mycobacterium Tuberculosis. 2019, a4238-a4238. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4238.Peer-Reviewed Original ResearchRole of MAIT Cells in Mycobacterium Intracellulare Infection In Vivo
Chan E, Aerts S, Choi S, Kwon Y, Brigl M, Honda J, Matsuda J, Gapin L, Bai X. Role of MAIT Cells in Mycobacterium Intracellulare Infection In Vivo. 2019, a4239-a4239. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4239.Peer-Reviewed Original ResearchAlpha-1-Antitrypsin Binds to Glucocorticoid Receptor to Induce Angiopoietin-Like Protein 4 Expression
Chan E, Bai A, Feng Z, Kadiyala V, Aerts S, Honda J, Li L, Tomasicchio M, Harbeck R, Sandhaus R, Gerber A, Bai X. Alpha-1-Antitrypsin Binds to Glucocorticoid Receptor to Induce Angiopoietin-Like Protein 4 Expression. 2019, a4544-a4544. DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a4544.Peer-Reviewed Original Research
2018
Epidemiologic Evidence of and Potential Mechanisms by Which Second-Hand Smoke Causes Predisposition to Latent and Active Tuberculosis
Bai X, Aerts SL, Verma D, Ordway DJ, Chan ED. Epidemiologic Evidence of and Potential Mechanisms by Which Second-Hand Smoke Causes Predisposition to Latent and Active Tuberculosis. Immune Network 2018, 18: e22. PMID: 29984040, PMCID: PMC6026693, DOI: 10.4110/in.2018.18.e22.Peer-Reviewed Original ResearchSecond-hand smokeSmoke exposureEpidemiologic linkSecond-hand smoke exposureCigarette smoke exposureAdditional relevant publicationsActive diseaseTB infectionActive tuberculosisSHS exposureTuberculosis infectionEpidemiologic evidenceImmune cellsPubMed searchHost immunityHealth maladiesPotential mechanismsRelevant publicationsTuberculosisInfectionRelevant papersDiseaseTBExposureKey words
2016
Inpatient Palliative Care for Neurological Disorders: Lessons from a Large Retrospective Series
Liu Y, Kline D, Aerts S, Youngwerth JM, Kutner JS, Sillau S, Kluger BM. Inpatient Palliative Care for Neurological Disorders: Lessons from a Large Retrospective Series. Journal Of Palliative Medicine 2016, 20: 59-64. PMID: 27898260, DOI: 10.1089/jpm.2016.0240.Peer-Reviewed Original ResearchConceptsProportion of patientsGoals of careChronic diagnosesAdvance directivesPalliative careNeurological diagnosisNeurological patientsNeurological disordersHospital-based palliative careInpatient palliative care servicesInpatient palliative care consultationPalliative care consult serviceCommon patient populationInpatient palliative carePalliative care consultationPalliative care servicesRetrospective case seriesTime of consultationLarge retrospective seriesProportion of peopleHospital neurologistsIschemic strokeCase seriesCommon diagnosisRetrospective series
2014
Determinants of Objectively Measured Physical Functional Performance in Early to Mid‐stage Parkinson Disease
Kluger BM, Brown RP, Aerts S, Schenkman M. Determinants of Objectively Measured Physical Functional Performance in Early to Mid‐stage Parkinson Disease. PM&R 2014, 6: 992-998. PMID: 24880056, PMCID: PMC4247341, DOI: 10.1016/j.pmrj.2014.05.013.Peer-Reviewed Original ResearchConceptsMid-stage Parkinson's diseaseUnified Parkinson's Disease Rating ScalePhysical functional performanceDisease Rating ScaleParkinson's diseaseNonmotor symptomsFunctional limitationsContinuous Scale Physical Functional Performance TestTertiary academic medical centerCognitive functionParkinson's Disease Rating ScaleCross-sectional baseline dataFunctional performance outcomesMid-stage diseaseProfound functional limitationsRandomized clinical trialsModerate Parkinson's diseaseAcademic medical centerFunctional performance testsOverall cognitive statusFunctional performanceCS-PFPStepwise linear regression modelAdvanced diseaseRegression models
2011
Nonmotor manifestations of dystonia: A systematic review
Kuyper DJ, Parra V, Aerts S, Okun MS, Kluger BM. Nonmotor manifestations of dystonia: A systematic review. Movement Disorders 2011, 26: 1206-1217. PMID: 21484874, PMCID: PMC3652664, DOI: 10.1002/mds.23709.Peer-Reviewed Original Research