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Rui Chang, PhD

Assistant Professor in Neuroscience and of Cellular and Molecular Physiology

Contact Information

Rui Chang, PhD



Rui Chang received his B.S. in Biological Sciences and Biotechnology from Tsinghua University, China in 2005. He then studied sensory transduction with Emily Liman and earned his Ph.D. in Neuroscience at the University of Southern California in 2011. He completed his postdoctoral training with Stephen Liberles at Harvard Medical School, where he investigated how body sensory cues are monitored by the brain through the vagus nerve, and how these internal signals regulate whole body physiology. He joined both the Department of Neuroscience and the Department of Cellular and Molecular Physiology at Yale University School of Medicine in January 2018.

The Chang lab uses state-of-the-art molecular, genetic, and imaging approaches including single-cell gene expression profiling, virus-based anatomical mapping, in vivo imaging, optogenetics, and chemogenetics to reveal the physiological functions of diverse organ-to-brain circuits. The goal is to better understand the important body-brain interface, and to develop novel neuronal-based therapeutic strategies for disease intervention.

Education & Training

  • Research Associate
    Harvard Medical School (2017)
  • Postdoctoral Fellow
    Harvard Medical School (2017)
  • PhD
    University of Southern California, Neuroscience (2011)
  • BS
    Tsinghua University, Biological Sciences and Biotechnology (2005)

Honors & Recognition

AwardAwarding OrganizationDate
McKnight Neurobiology of Brain Disorders AwardMcKnight Foundation2021
NIH Director’s New Innovator AwardNIH2019
Kavli Faculty Innovative Research AwardKavli Institute for Neuroscience, Yale University2019
K01 Mentored Research Scientist Development AwardNIH-NIDDK2017
Keystone Symposia Future of Science Fund ScholarshipKeystone Symposia2016
American Heart Association Postdoctoral FellowshipAmerican Heart Association2016
Outstanding Postdoctoral Fellow AwardHarvard Medical School2015
Harrison Kutz AwardUniversity of Southern California2011
Wu Shunde ScholarshipTsinghua University2003
Wu Zhande ScholarshipTsinghua University2002

Departments & Organizations