Rita Milewski, MD, PhD
Associate Professor of Surgery (Cardiac)DownloadHi-Res Photo
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Cardiac Surgery
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Associate Professor of Surgery (Cardiac)
Appointments
Cardiac Surgery
Associate Professor on TermPrimary
Other Departments & Organizations
- All Institutions
- Cardiac Surgery
- Surgery
- Yale Medicine
- Yale New Haven Health System
Education & Training
- Fellowship
- University of Pennsylvania (2017)
- Fellowship
- Children's Hospital of Pennsylvania (1994)
- Residency
- State University of New York - Buffalo (1993)
- Residency
- University of Minnesota Medical Center (1986)
- MD
- Northwestern University (1984)
Board Certifications
Thoracic & Cardiac Surgery
- Certification Organization
- AB of Thoracic Surgery
- Original Certification Date
- 1996
General Surgery
- Certification Organization
- AB of Surgery
- Original Certification Date
- 1994
Research
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Rita Milewski's published research.
Publications Timeline
A big-picture view of Rita Milewski's research output by year.
Prashanth Vallabhajosyula, MD, MS
Roland Assi, MD, MMS, FACS, MMSc
Andrea Amabile, MD
Irbaz Hameed, MD, PhD
Matthew Williams, MD
14Publications
169Citations
Publications
2025
Prosthesis–Patient Mismatch Following Aortic Valve Replacement—A Comprehensive Review
Talapaneni S, Ahmad D, Khandelwal M, Mesiha M, Jalali P, Celik N, Tabraiz S, Dankwa S, Hameed I, Milewski R, Vallabhajosyula P. Prosthesis–Patient Mismatch Following Aortic Valve Replacement—A Comprehensive Review. Journal Of Clinical Medicine 2025, 14: 8868. PMID: 41464770, PMCID: PMC12733721, DOI: 10.3390/jcm14248868.Peer-Reviewed Original ResearchCitationsConceptsProsthesis-patient mismatchAortic valve replacementPatient's body surface areaBioprosthetic valve fractureValve replacementTransvalvular gradientSurgical valvesLeft ventricular mass regressionAccurate preoperative imagingRates of heart failureCoronary flow abnormalitiesLong-term outcomesBody surface areaValve-in-valveEffective orifice areaIndividual patient anatomyNarrative reviewAnnular enlargementPreoperative imagingLate mortalityPatient survivalClinical outcomesCardiac remodelingMass regressionCoronary access
2024
Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis
Ram C, Yousef S, Ma W, Vallabhajosyula I, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Williams M, Geirsson A, Vallabhajosyula P. Living in disadvantaged neighborhoods linked to less intervention for severe aortic stenosis. Scientific Reports 2024, 14: 4952. PMID: 38418864, PMCID: PMC10902341, DOI: 10.1038/s41598-024-52660-w.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAortic valve replacementSevere aortic stenosisAfrican American raceArea Deprivation IndexAortic stenosisSevere ASArea deprivation index rankAortic valve replacement ratesAmerican raceAortic valve interventionPresentation of sepsisDiagnosis of ASADI groupValve replacementValve interventionDeprived neighbourhoodsAV interventionDisadvantaged neighborhoodsPatientsFemale genderDeprivation indexHigh-ADI groupLow-ADI groupStenosisRaceBicuspid Aortic Valve: Current Therapeutic Strategies
Usman Bin Mahmood S, Vallabhajosyula P, Milewski R. Bicuspid Aortic Valve: Current Therapeutic Strategies. Cardiology And Cardiovascular Medicine 2024, 1 DOI: 10.5772/intechopen.113315.Peer-Reviewed Original ResearchAltmetricConceptsBicuspid aortic valveAortic valveTherapeutic strategiesValve-sparing root reimplantationBicuspid aortic valve patientsBAV syndromeSurgical therapeutic strategiesAortic valve replacementAortic valve patientsAortic valve stenosisAortic valve repairLong-term outcomesCurrent therapeutic strategiesBAV populationAorta replacementBentall procedureValve patientsValve replacementValve stenosisRoot reimplantationValve repairValvular pathologySurgical proceduresGeneral populationIndividualized approach
2023
Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study
Mangino J, Firstenberg M, Milewski R, Rhys-Williams W, Lees J, Dane A, Love W, Moreno J. Exeporfinium chloride (XF-73) nasal gel dosed over 24 hours prior to surgery significantly reduced Staphylococcus aureus nasal carriage in cardiac surgery patients: Safety and efficacy results from a randomized placebo-controlled phase 2 study. Infection Control And Hospital Epidemiology 2023, 44: 1171-1173. PMID: 36951472, PMCID: PMC10369221, DOI: 10.1017/ice.2023.17.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and Concepts
2022
Direct relationship between transvalvular velocity and cardiac dysfunction, morbidity, and mortality in patients with aortic stenosis
Yousef S, Amabile A, Ram C, Singh S, Agarwal R, Milewski R, Assi R, Patel P, Krane M, Geirsson A, Vallabhajosyula P. Direct relationship between transvalvular velocity and cardiac dysfunction, morbidity, and mortality in patients with aortic stenosis. Journal Of Cardiac Surgery 2022, 37: 5052-5062. PMID: 36378856, DOI: 10.1111/jocs.17199.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsDegree of ASCardiac structural changesAortic stenosisSevere symptomatic aortic stenosisEnd-organ morbiditiesStructural cardiac changesSymptomatic aortic stenosisEnd-organ diseaseKaplan-Meier curvesRisk of mortalityTransvalvular flow velocityCochran-Armitage testCause mortalityPatient characteristicsCardiac changesCardiac dysfunctionPatient morbidityTransvalvular velocityCurrent guidelinesGroup BGroup ACaucasian raceHigh riskCox modelEarly intervention
2021
CARDIAC STRUCTURAL CHANGES, END-ORGAN MORBIDITIES AND MORTALITY RELATE TO AORTIC STENOSIS IN A DEGREE-REPONSE RELATIONSHIP
Yousef S, Ram C, Singh S, Agarwal R, Milewski R, Assi R, Geirsson A, Vallabhajosyula P. CARDIAC STRUCTURAL CHANGES, END-ORGAN MORBIDITIES AND MORTALITY RELATE TO AORTIC STENOSIS IN A DEGREE-REPONSE RELATIONSHIP. Journal Of The American College Of Cardiology 2021, 77: 1750. DOI: 10.1016/s0735-1097(21)03106-5.Peer-Reviewed Original Research
2018
Hypoxia and Complications of Oxygenation in Extracorporeal Membrane Oxygenation
Alexis-Ruiz A, Ghadimi K, Raiten J, Mackay E, Laudanski K, Cannon J, Ramakrishna H, Evans A, Augoustides J, Vallabhajosyula P, Milewski R, McDonald M, Patel P, Vernick W, Gutsche J. Hypoxia and Complications of Oxygenation in Extracorporeal Membrane Oxygenation. Journal Of Cardiothoracic And Vascular Anesthesia 2018, 33: 1375-1381. PMID: 30082128, DOI: 10.1053/j.jvca.2018.05.028.Peer-Reviewed Educational MaterialsCitationsAltmetric
2017
Peripheral Blood Gene Expression Changes Associated With Primary Graft Dysfunction After Lung Transplantation
Diamond J, Cantu E, Porteous M, Suzuki Y, Meyer K, Lederer D, Milewski R, Arcasoy S, D’Ovidio F, Bacchetta M, Sonett J, Singh G, Costa J, Tobias J, Rodriguez H, Van Deerlin V, Olthoff K, Shaked A, Chang B, Christie J, Investigators F. Peripheral Blood Gene Expression Changes Associated With Primary Graft Dysfunction After Lung Transplantation. American Journal Of Transplantation 2017, 17: 1770-1777. PMID: 28117940, PMCID: PMC5489369, DOI: 10.1111/ajt.14209.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPrimary graft dysfunctionGraft dysfunctionLung transplantationPeripheral blood gene expressionFirst transplant yearImmune regulation genesInflammasome-related proteinsDays of transplantBlood of patientsAdaptive immunity genesBlood gene expressionAllograft reperfusionTransplant yearClinical trialsPGD developmentGrade 3T cellsTransplantGene expressionHypothesis-driven genesRNA expressionGene expression changesReperfusionAllograftsPatients
2016
The Perioperative Lung Transplant Virome: Torque Teno Viruses Are Elevated in Donor Lungs and Show Divergent Dynamics in Primary Graft Dysfunction
Abbas A, Diamond J, Chehoud C, Chang B, Kotzin J, Young J, Imai I, Haas A, Cantu E, Lederer D, Meyer K, Milewski R, Olthoff K, Shaked A, Christie J, Bushman F, Collman R. The Perioperative Lung Transplant Virome: Torque Teno Viruses Are Elevated in Donor Lungs and Show Divergent Dynamics in Primary Graft Dysfunction. American Journal Of Transplantation 2016, 17: 1313-1324. PMID: 27731934, PMCID: PMC5389935, DOI: 10.1111/ajt.14076.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsMeSH KeywordsAdultAgedCase-Control StudiesDNA, ViralFemaleFollow-Up StudiesGenome, ViralGraft RejectionGraft SurvivalHumansLung TransplantationMaleMetagenomicsMiddle AgedPerioperative CarePrimary Graft DysfunctionPrognosisProspective StudiesRespiratory SystemRisk FactorsTissue DonorsTorque teno virusConceptsPrimary graft dysfunctionTorque teno virusGraft dysfunctionDonor lungsTTV levelsGreater immune activationTTV DNA levelsStandard clinical assaysRespiratory tract bacteriaPGD casesQuantitative polymerase chain reactionEarly morbidityLung allograftsLung transplantationPGD statusTTV replicationBronchoalveolar lavageControl recipientsImmune activationPolymerase chain reactionHealthy controlsBrain deathRecipient pairsTissue injuryDonor organs
2014
004DISTAL AORTIC REINTERVENTION AFTER SURGERY FOR ACUTE TYPE A AORTIC DISSECTION: OPEN VERSUS ENDOVASCULAR REPAIR
Rylski B, Beyersdorf F, Desai N, Siepe M, Kari F, Vallabhajosyula P, Milewski R, Bavaria J. 004DISTAL AORTIC REINTERVENTION AFTER SURGERY FOR ACUTE TYPE A AORTIC DISSECTION: OPEN VERSUS ENDOVASCULAR REPAIR. Interdisciplinary CardioVascular And Thoracic Surgery 2014, 19: s2-s2. DOI: 10.1093/icvts/ivu276.4.Peer-Reviewed Original ResearchConceptsDistal aortic pathologyDistal reinterventionDissection repairEndovascular groupHospital mortalityAcute typeAortic pathologyAortic dissection type AOpen Versus Endovascular RepairOpen repair patientsAortic reinterventionEndovascular patientsLate reinterventionSpinal ischaemiaEndovascular reinterventionEndovascular repairRepair patientsAortic dissectionConsecutive patientsEndovascular approachSurgical repairTertiary centerMedian timeProximal repairEndovascular intervention
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Cardiac Surgery
P.O. Box 208039
New Haven, CT 06520
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