Featured Publications
Characterization of a morphogenetic furrow specific Gal4 driver in the developing Drosophila eye
Sarkar A, Gogia N, Farley K, Payton L, Singh A. Characterization of a morphogenetic furrow specific Gal4 driver in the developing Drosophila eye. PLOS ONE 2018, 13: e0196365. PMID: 29702674, PMCID: PMC5922546, DOI: 10.1371/journal.pone.0196365.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, Genetically ModifiedBody PatterningCell DifferentiationDrosophila melanogasterDrosophila ProteinsGene Expression ProfilingGene Expression Regulation, DevelopmentalGreen Fluorescent ProteinsImmunohistochemistryIntracellular Signaling Peptides and ProteinsNuclear ProteinsPhenotypeProtein Serine-Threonine KinasesRetinaRetinal NeuronsTrans-ActivatorsTranscription FactorsTransforming Growth Factor betaWnt1 ProteinYAP-Signaling Proteins
2024
Genetic mechanism regulating diversity in the placement of eyes on the head of animals
Puli O, Gogia N, Chimata A, Yorimitsu T, Nakagoshi H, Kango-Singh M, Singh A. Genetic mechanism regulating diversity in the placement of eyes on the head of animals. Proceedings Of The National Academy Of Sciences Of The United States Of America 2024, 121: e2316244121. PMID: 38588419, PMCID: PMC11032433, DOI: 10.1073/pnas.2316244121.Peer-Reviewed Original ResearchConceptsMorphogen gradientsCell fateRegulate Wg signalingEye developmentGradients of signaling moleculesHomeodomain transcription factorRetinal determination genesWg signalingWnt/Wg signalingGain-of-functionWg expressionEye fateDefective proventriculusDetermination genesEye genesGenetic machineryTranscription factorsRetinal cell fateDevelopmental defectsPatterning cuesMorphogenGenesHead vertexFacial anomaliesFate