Chapter 8 Exploring the role of protein quality control in aging and age-associated neurodegenerative diseases
Gogia N, Olmos V, Haidery F, Luttik K, Tejwani L, Lim J. Chapter 8 Exploring the role of protein quality control in aging and age-associated neurodegenerative diseases. 2022, 139-171. DOI: 10.1016/b978-0-323-90235-9.00012-4.ChaptersPQC systemAge-associated neurodegenerative diseasesAge-related neurodegenerative diseasesProtein quality control systemCell deathNeurodegenerative diseasesProtein quality controlHallmark of agingAlters cellular functionCellular proteomeCellular functionsProtein misfoldingQuality control systemCellular agingBiological processesPostmitotic natureNeuronal cell deathProteinDisease symptomsEfficient clearanceTherapeutic targetCellsDisease conditionsNervous system tissueEffective therapeuticsExploring the efficacy of natural products in alleviating Alzheimer’s disease
Deshpande P, Gogia N, Singh A. Exploring the efficacy of natural products in alleviating Alzheimer’s disease. Neural Regeneration Research 2019, 14: 1321-1329. PMID: 30964049, PMCID: PMC6524497, DOI: 10.4103/1673-5374.253509.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPotential therapeutic targetAnimal model systemsTherapeutic targetAlzheimer's diseaseNeurodegenerative disordersOnset of ADProgressive neurodegenerative disorderCentral nervous systemClinical trialsTau tanglesDirect cureSide effectsNervous systemCognitive defectsDiseaseMitochondrial dysfunctionReactive oxygen speciesGenetic mutationsAberrant signalingSpecific diseasesPsychological problemsCell deathPlaquesDisordersOxygen species