Mariya Rozenblit, MD
Assistant Professor of Medicine (Medical Oncology)Cards
About
Titles
Assistant Professor of Medicine (Medical Oncology)
Biography
Dr. Mariya Rozenblit is an Assistant Professor of Medicine in the section of Medical Oncology and cares for patients with a clinical focus on breast cancer. She completed her Fellowship in Medical Oncology-Hematology at Yale, Residency in Internal Medicine at NYU, and received her medical degree from Icahn School of Medicine. She is involved in educating medical students, residents, and fellows at Yale. Outside of the clinic, her focus is translational research with an interest in biomarker driven trial development in breast cancer.
In 2020, she was the recipient of the ASCO Conquer Cancer Foundation Young Investigator Award for her project, “Using single nucleotide variants of high functional importance to predict the risk of developing breast cancer in young women with high risk family history.” This award is for promising investigators to encourage and promote quality research in clinical oncology. In 2022, she was the recipient of the Susan G. Komen Career Catalyst Research Grant for her project, "Curing de novo oligometastatic HER2+ breast cancer". This grant is to foster promising breast cancer researchers by providing support for up to three years.
Appointments
Medical Oncology and Hematology
Assistant ProfessorPrimary
Other Departments & Organizations
- Center for Breast Cancer
- Genomics, Genetics, and Epigenetics
- Internal Medicine
- Janeway Society
- Medical Oncology and Hematology
- Palade House Affiliates
- Yale Cancer Center
- Yale Medicine
- Yale New Haven Health System
Education & Training
- Internal Medicine Resident
- NYU Langone Medical Center (2018)
- MD
- Icahn School of Medicine at Mount Sinai (2015)
- BA
- Columbia University, Biology (2009)
Research
Publications
2026
Ultra-high tumor mutation burden breast cancer: genomic profiling and real-world immunotherapy results
Fanucci K, Rozenblit M, Quintanilha J, Graf R, Fischbach N, Pelletier M, Sivapiragasam A, Kumar P, Kallem M, Sokol E, Sivakumar S, Pavlick D, Ross J, Lustberg M, Pusztai L. Ultra-high tumor mutation burden breast cancer: genomic profiling and real-world immunotherapy results. Npj Breast Cancer 2026 PMID: 42162005, DOI: 10.1038/s41523-026-00965-6.Peer-Reviewed Original ResearchInvest where impact begins: recommendations from Breast Cancer Research Foundation Early Career Investigator Working Group (Part 1 of 2)
Abdou Y, Rozenblit M, Trapani D, Zerdes I, Boudreau E, Zhou Y, Adam V, Barrios C, Bousrih C, Branch V, Carey L, Cameron D, Chen S, Chua B, Davidson N, Domchek S, El-Abed S, El-Ashry D, Flowers M, Foldi J, Garber J, Goulioti T, Hodgdon C, Hung J, Klar N, Norton L, Parajuli R, Piccart M, Pollastro T, Santa-Maria C, Schumacher-Wulf E, Stecklein S, Thulin A, Tovey H, Winer E, Wolff A, Lin N, O’Reilly S. Invest where impact begins: recommendations from Breast Cancer Research Foundation Early Career Investigator Working Group (Part 1 of 2). Npj Breast Cancer 2026, 12: 69. PMID: 42115634, PMCID: PMC13161217, DOI: 10.1038/s41523-026-00940-1.Commentaries, Editorials and LettersCurrent Management Practices of De Novo Oligometastatic Breast Cancer: Real-World Data From a Physician Survey.
Odzer N, Wei W, Lustberg M, Pusztai L, Rozenblit M. Current Management Practices of De Novo Oligometastatic Breast Cancer: Real-World Data From a Physician Survey. JCO Oncology Practice 2026, op2500413. PMID: 41616223, DOI: 10.1200/op-25-00413.Peer-Reviewed Original ResearchMutational landscape of normal breast tissues adjacent to invasive breast cancer
Suwalska A, Rozenblit M, Harigopal M, Dai J, Liu M, Townsend J, Marczyk M, Pusztai L. Mutational landscape of normal breast tissues adjacent to invasive breast cancer. Cell Reports Medicine 2026, 7: 102543. PMID: 41512875, PMCID: PMC12866091, DOI: 10.1016/j.xcrm.2025.102543.Peer-Reviewed Original Research
2025
HER2‐Targeted Antibody‐Drug Conjugate Toxicities in Breast Cancer
Lee S, Kahn A, Rozenblit M, George M, Ortiz C, Lustberg M. HER2‐Targeted Antibody‐Drug Conjugate Toxicities in Breast Cancer. Cancer Medicine 2025, 14: e71415. PMID: 41361931, PMCID: PMC12685761, DOI: 10.1002/cam4.71415.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPrognostic Value of Circulating Tumor DNA in HR+/HER2− Stage I–III Breast Cancer: A Systematic Review
Ajjawi I, Rozenblit M, Rios-Hoyo A, Lustberg M. Prognostic Value of Circulating Tumor DNA in HR+/HER2− Stage I–III Breast Cancer: A Systematic Review. Cancers 2025, 17: 2831. PMID: 40940926, PMCID: PMC12427406, DOI: 10.3390/cancers17172831.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsSurgeon Attitudes on the Management of de novo Oligometastatic Breast Cancer
Brennan M, Plichta J, Rozenblit M, Flanagan M. Surgeon Attitudes on the Management of de novo Oligometastatic Breast Cancer. Annals Of Surgical Oncology 2025, 32: 9478-9479. PMID: 40767935, DOI: 10.1245/s10434-025-17912-7.Commentaries, Editorials and LettersErratum: De Novo Oligometastatic Breast Cancer
Pusztai L, Rozenblit M, Dubsky P, Bachelot T, Kirby A, Linderholm B, White J, Chmura S, Carey L, Chua B, Miller K. Erratum: De Novo Oligometastatic Breast Cancer. Journal Of Clinical Oncology 2025, 43: 2758-2758. PMID: 40690726, PMCID: PMC12521985, DOI: 10.1200/jco-25-01626.Commentaries, Editorials and LettersGenomic landscape and homologous recombination repair deficiency signature in stage I-III and de novo stage IV primary breast cancers
Jeon J, Chen K, Madison R, Schrock A, Sokol E, Levy M, Rozenblit M, Huang R, Pusztai L. Genomic landscape and homologous recombination repair deficiency signature in stage I-III and de novo stage IV primary breast cancers. The Oncologist 2025, 30: oyaf089. PMID: 40421962, PMCID: PMC12107548, DOI: 10.1093/oncolo/oyaf089.Peer-Reviewed Original ResearchAccelerated Aging in Cancer and Cancer Treatment: Current Status of Biomarkers
Abraham S, Parekh J, Lee S, Afrin H, Rozenblit M, Blenman K, Perry R, Ferrucci L, Liu J, Irwin M, Lustberg M. Accelerated Aging in Cancer and Cancer Treatment: Current Status of Biomarkers. Cancer Medicine 2025, 14: e70929. PMID: 40322791, PMCID: PMC12051034, DOI: 10.1002/cam4.70929.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
Clinical Trials
Current Trials
A pilot study to evaluate biomarkers and safety of dapagliflozin concomitant with neoadjuvant therapy for patient with HER2-negative early-stage breast cancer and hyperinsulinemia
IRB ID2000033529RoleSub InvestigatorPrimary Completion Date12/31/2025Recruiting Participants
Academic Achievements & Community Involvement
Clinical Care
Overview
Mariya Rozenblit, MD, is a medical oncologist who specializes in treating patients with different types of breast cancer, from ductal carcinoma in situ (DCIS), the most common type of breast cancer, to metastatic breast cancer, or stage IV breast cancer.
Dr. Rozenblit research focuses on biomarker-driven trial development in breast cancer. These types of clinical trials allow researchers to investigate how patients (including those with different cancer mutations) respond to available medications. For example, Dr. Rozenblit co-authored a study that found patients younger than 40 with advanced breast cancer often suffer a worse prognosis and more severe symptoms than older patients.
She has received the American Society of Clinical Oncology’s Conquer Cancer Foundation’s Young Investigator Award and the Susan G. Komen Cancer Catalyst Research Grant. Dr. Rozenblit is an assistant professor of medicine (medical oncology) at Yale School of Medicine.
Clinical Specialties
Fact Sheets
Breast Cancer
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Yale Medicine News
News & Links
Media
Smilow Shares: Breast Cancer Awareness Month: Early-Stage Breast Cancer
October 9, 2025
Moderated by: Rachel Greenup, MD, MPH
Presentations by:
Elizabeth Berger, MD, MS, FACS
Mariya Rozenblit, MD
Siba Haykal, MD, PhD, FRCS, FACS
News
- December 13, 2025
Yale research advances presented at San Antonio Breast Cancer Symposium annual meeting
- October 27, 2025
YCC Publications 2025
- May 22, 2025
2025 ASCO Conquer Cancer Grants & Awards Announced
- April 08, 2025
Comprehensive Breast Cancer Care at Smilow Cancer Hospital at Greenwich and Stamford
Get In Touch
Contacts
Administrative Support
Locations
Patient Care Locations
Are You a Patient? View this doctor's clinical profile on the Yale Medicine website for information about the services we offer and making an appointment.
Events
Everyone Maryam Lustberg, MD, MPH - Craig Cassanelli - Adriana Kahn, MD - Mariya Rozenblit, MD - Sarah Elizabeth Schellhorn, MD - Mitchell Elliott, MD, FRCPC