Justin "Jay" Bader, MD
Hospital ResidentDownloadHi-Res Photo
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T32 Clinical Oncology Research Fellow, Department of Surgery
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Hospital Resident
T32 Clinical Oncology Research Fellow, Department of Surgery
Biography
Hometown: Minnetonka, Minnesota
Undergraduate: MIT
Medical School: Dartmouth
Clinical Interests: Surgical Oncology and Thoracic Surgery
Research Interests: Cancer Immunology, Peritoneal Surface Malignancies, Mesothelioma, Immunotherapy, Clinical Trial Design and Implementation, Robotic Surgery, AI-application/analysis, and Computational/Prediction Modeling
Hobbies: Ice hockey, golf, rock climbing, billiards, coding, pickle-ball, hiking, gardening, and camping
Last Updated on February 11, 2026.
Departments & Organizations
Education & Training
- MD
- Dartmouth (2022)
- BS
- MIT, Chemistry and Biology (2017)
Research
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Research at a Glance
Yale Co-Authors
Frequent collaborators of Justin "Jay" Bader's published research.
Publications Timeline
A big-picture view of Justin "Jay" Bader's research output by year.
Cassius Iyad Ochoa Chaar, MD, MPH, MS, RPVI
Kiran Turaga, MD, MPH
Michael Cecchini, MD
Raghav Sundar, MD, PhD
Elizabeth Godfrey, MD
Judy Li
13Publications
153Citations
Publications
2026
PIK3CA Mutations in Early-Onset Appendiceal Adenocarcinoma
Gupta P, Gujarathi R, Qiao L, Godfrey E, Schultz K, Butensky S, Bader J, Sundar R, Cecchini M, Shergill A, Sheltzer J, Turaga K. PIK3CA Mutations in Early-Onset Appendiceal Adenocarcinoma. JCO Precision Oncology 2026, 10: e2500741. PMID: 41712872, DOI: 10.1200/po-25-00741.Peer-Reviewed Original ResearchAltmetricMeSH Keywords and ConceptsConceptsAssociated with worse OSAppendiceal cancerAppendiceal adenocarcinomaOverall survivalMutation profilesMultivariate Cox proportional hazards modelKaplan-Meier survival analysisTime of surgeryAssociated with survivalCox proportional hazards modelsProportional hazards modelLate-onset diseaseMetastatic diseaseMucinous tumorsPIK3CA mutationsMutation statusPrognostic assessmentRetrospective analysisMultivariate analysisAdenocarcinomaTherapeutic strategiesPatientsSurvival analysisHazards modelDemographic featuresConsensus Molecular Subtypes Inform HIPEC Agent Selection in Colorectal Cancer Peritoneal Metastases
Gupta P, Godfrey E, Schultz K, Qiao L, Aguirre N, Bader J, Foote M, Shen J, Shergill A, Cecchini M, Sundar R, Sheltzer J, Turaga K. Consensus Molecular Subtypes Inform HIPEC Agent Selection in Colorectal Cancer Peritoneal Metastases. Annals Of Surgical Oncology 2026, 1-6. PMID: 41634518, DOI: 10.1245/s10434-025-19057-z.Peer-Reviewed Original ResearchThis study investigates drug sensitivity in colorectal cancer peritoneal metastases, showing CMS4 tumors respond better to mitomycin-C and irinotecan, informing personalized chemotherapy strategies.Deep learning approach for critical exposure during division of the inferior mesenteric artery in colorectal surgery
Bader JM, Sun X, Rosenfelt T, Ramirez-Hardy A, Vitchutripop T, Srinivasan A, Pantel H, Khanna A, Rakita D. Deep learning approach for critical exposure during division of the inferior mesenteric artery in colorectal surgery. J Robotic Surg 2026, 20: 155. DOI: 10.1007/s11701-025-03121-7.Peer-Reviewed Original Research
2025
Robotic Approach to Multivisceral Resection for Gastrointestinal Stromal Tumor With En Bloc Resection of the Stomach, Distal Pancreas, and Spleen: A Case Report
Bader J, Liu S, Billingsley K. Robotic Approach to Multivisceral Resection for Gastrointestinal Stromal Tumor With En Bloc Resection of the Stomach, Distal Pancreas, and Spleen: A Case Report. Cureus 2025, 17: e96479. PMID: 41384208, PMCID: PMC12691104, DOI: 10.7759/cureus.96479.Peer-Reviewed Original ResearchConceptsGastrointestinal stromal tumorsStromal tumorsInvasion of adjacent organsBloc distal pancreatectomyHigh-risk featuresUncomplicated postoperative recoveryInterdisciplinary tumor boardEn-bloc resectionAdjuvant imatinibMultivisceral resectionSurgical resectionDistal pancreatectomyExtraluminal growthIntraoperative findingsBloc resectionMesenchymal neoplasmsAdjacent organsDistal pancreasCase reportIntraoperative challengesTumor boardPostoperative recoveryPartial gastrectomyResectionRobotic approachFrailty and functional decline after elective endovascular abdominal aortic aneurysm repair in octogenarians
Li J, Slade M, Gill T, Bader J, Guzman R, Tonnessen B, Kuwayama D, Dardik A, Cardella J, Ochoa Chaar C. Frailty and functional decline after elective endovascular abdominal aortic aneurysm repair in octogenarians. Journal Of Vascular Surgery 2025, 83: 79-90.e2. PMID: 40835162, PMCID: PMC13005939, DOI: 10.1016/j.jvs.2025.08.011.Peer-Reviewed Original ResearchAltmetricConceptsElective endovascular abdominal aortic aneurysm repairEndovascular abdominal aortic aneurysm repairAbdominal aortic aneurysm repairAortic aneurysm repairModified Frailty IndexFollow-upRisk Analysis IndexRisk factorsAneurysm repairValidation cohortDevelopment cohortEastern Cooperative Oncology Group performance statusAsymptomatic infrarenal abdominal aortic aneurysmFunctional declineInfrarenal abdominal aortic aneurysmVascular Quality Initiative (VQI) databaseFrailty assessmentCongestive heart failureAbdominal aortic aneurysmLong-term mortality riskChronic obstructive pulmonary diseaseFrailty indexObstructive pulmonary diseasePreoperative factorsPreoperative comorbiditiesProlonged Survival in Mesothelioma Patients Without Surgical Resection: A National Cancer Database Analysis
Zhan P, Canavan M, Bader J, Boffa D, Resio B, Woodard G. Prolonged Survival in Mesothelioma Patients Without Surgical Resection: A National Cancer Database Analysis. The Annals Of Thoracic Surgery 2025, 121: 633-642. PMID: 40588180, DOI: 10.1016/j.athoracsur.2025.06.015.Peer-Reviewed Original ResearchCitationsAltmetricConceptsNational Cancer DatabaseLong-term survivalSurgical resectionOverall survivalPleural mesotheliomaClinical stage I diseaseCurative-intent surgical resectionNational Cancer Database dataNational Cancer Database AnalysisDiagnosis of malignant pleural mesotheliomaDeclined surgical resectionEpithelioid histological typeChemotherapy-treated patientsNonsurgically treated patientsStage I diseaseMalignant pleural mesotheliomaMultivariate logistic regression modelPropensity-matched cohortPropensity score matchingI diseaseSurvival benefitHistological typeSurgery 2Prolonged survivalCancer DatabasePrediction model for safe contrast volume thresholds to prevent postcontrast acute kidney injury after endovascular abdominal aortic aneurysm repair
Bader J, Li Y, Lee C, Li J, Said S, Slade M, Huang Y, Kuwayama D, Guzman R, Ochoa Chaar C. Prediction model for safe contrast volume thresholds to prevent postcontrast acute kidney injury after endovascular abdominal aortic aneurysm repair. Journal Of Vascular Surgery 2025, 82: 833-844.e3. PMID: 40490161, DOI: 10.1016/j.jvs.2025.05.041.Peer-Reviewed Original ResearchCitationsAltmetricConceptsElective endovascular abdominal aortic aneurysm repairEndovascular abdominal aortic aneurysm repairRisk of PC-AKIAbdominal aortic aneurysm repairMultivariate logistic regression analysisAortic aneurysm repairPC-AKIAcute kidney injuryLogistic regression analysisPerioperative mortalityAneurysm repairKidney injuryComplication of endovascular abdominal aortic aneurysm repairPatient characteristicsIncidence of preoperative comorbiditiesPost-contrast acute kidney injuryPostcontrast acute kidney injuryAssociated with development of chronic kidney diseaseAssociated with perioperative mortalityDevelopment of chronic kidney diseaseVascular Quality Initiative databasePreoperative patient characteristicsKaplan-Meier analysisProlonged hospital stayRenal artery stentingA Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for Appendiceal and Colorectal Adenocarcinoma with Peritoneal Metastasis
Bader J, Ospina A, Liu S, Reddy B, Gupta P, Tomlin R, Cecchini M, Sundar R, Turaga K. A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for Appendiceal and Colorectal Adenocarcinoma with Peritoneal Metastasis. Annals Of Surgical Oncology 2025, 32: 5784-5794. PMID: 40445508, DOI: 10.1245/s10434-025-17517-0.Peer-Reviewed Original ResearchCitationsAltmetricConceptsHyperthermic intraperitoneal chemotherapyPeritoneal surface malignanciesStandard of careHIPEC regimensColorectal cancerAppendiceal cancerCytoreductive surgeryIntraperitoneal chemotherapyPeritoneal metastasisTumor susceptibilityClinical trialsStandard of care regimenOpen-label clinical trialColorectal peritoneal metastasesHigh-grade appendicealRegimens to patientsPatient standard of careChemotherapy combinationsDiagnostic laparoscopySurface malignanciesSingle-centerChemotherapy sensitivityBiopsy tissueBackgroundCurrent treatmentsColorectal adenocarcinomaAdherence to SVS Abdominal Aortic Aneurysm Guidelines Among Patients Detected by AI-Based Algorithm
Wilson E, Yao K, Kostiuk V, Bader J, Loh S, Mojibian H, Fischer U, Ochoa Chaar C, Aboian E. Adherence to SVS Abdominal Aortic Aneurysm Guidelines Among Patients Detected by AI-Based Algorithm. Annals Of Vascular Surgery 2025, 120: 108-114. PMID: 40349830, DOI: 10.1016/j.avsg.2025.05.007.Peer-Reviewed Original ResearchCitationsAltmetricConceptsAbdominal aortic aneurysmAdherent patientsSurgical interventionAbdominal aortic aneurysm patientsNon-adherent patientsTertiary care centerFollow-up adherenceFollow-up algorithmSVS guidelinesImaging surveillanceSurgical criteriaAneurysm sizeAortic aneurysmIdentified patientsPati entsSurveillance adherenceVascular providersImaging scansDeceased patientsPatientsPhysician evaluationCare centerPatient outcomesStatistical significanceNo significant age differences
2021
Resident and circulating memory T cells persist for years in melanoma patients with durable responses to immunotherapy
Han J, Zhao Y, Shirai K, Molodtsov A, Kolling FW, Fisher JL, Zhang P, Yan S, Searles TG, Bader JM, Gui J, Cheng C, Ernstoff MS, Turk MJ, Angeles CV. Resident and circulating memory T cells persist for years in melanoma patients with durable responses to immunotherapy. Nature Cancer 2021, 2: 300-311. PMID: 34179824, PMCID: PMC8223731, DOI: 10.1038/s43018-021-00180-1.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsT cell responsesMemory T cellsT cellsEffector memory T cellsResident memory T cellsMetastatic melanoma survivorsT cells persistStrong prognostic valueT cell receptorDurable responsesMemory CD8Melanoma patientsCancer survivorsPrognostic valueCancer immunotherapyMelanoma survivorsCells persistClonal repertoireSingle-cell RNA sequencingImmunotherapyTumorsExceptional responsePatient's skinClonotypesBlood
Clinical Trials
Current Trials
A Feasibility Study of Mass-Based Response Drug Screening to Guide Personalized Hyperthermic Intraperitoneal Chemotherapy for High-Grade Appendiceal and Colorectal Adenocarcinoma With Peritoneal Metastasis
IRB ID2000038133RoleSub InvestigatorPrimary Completion Date02/15/2027Recruiting Participants
Academic Achievements & Community Involvement
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Activities
activity Radiographic Tumor Regression as a Predictor for Pathologic Response after Neoadjuvant Therapy for Non-Small Cell Lung Cancer
05/04/2026 - PresentOral PresentationAmerican Association for Thoracic Surgery (AATS)DetailsChicago, IL, United StatesCollaboratorsactivity Optimizing Safety in Robotic-Assisted Right Hepatectomy: Technique for Complete Vascular Control of the Left and Middle Hepatic Veins Prior to Liver Transection
03/07/2026 - PresentOral PresentationSociety of Surgical Oncology (SSO)DetailsPhoenix, AZ, United StatesCollaboratorsactivity Comprehensive molecular profiling predicts survival among North American patients with mesothelioma
03/06/2026 - PresentOral PresentationSociety of Surgical Oncology (SSO)DetailsPhoenix, AZ, United StatesCollaboratorsactivity Comprehensive molecular profiling predicts survival among North American patients with mesothelioma
02/15/2026 - PresentOral PresentationAdvanced Cancer Therapies (ACT)DetailsFort Lauderdale, FL, United StatesCollaboratorsactivity Tumor Profiling And Immune Cell Infiltration Of Semi-solid Lung Nodules - Translating Pathology To Optimize Surgical Decision-making
10/06/2025 - PresentOral PresentationAmerican College of Surgeons (ACS)DetailsChicago, IL, United StatesCollaborators
Honors
honor T32 Clinical Oncology Research Grant 2025-2026
06/15/2025Yale School of Medicine AwardYale Medical Oncology Departmenthonor Jack L. Cronenwett Scholarship
03/18/2025National AwardVascular Quality Initiativehonor Surgery Mastery Grant
01/02/2025Yale School of Medicine AwardYale Department of Surgeryhonor T32 Clinical Oncology Research Grant 2024-2025
06/15/2024Yale School of Medicine AwardYale Medical Oncology Departmenthonor Academic Development Grant
02/05/2024Yale School of Medicine AwardYale Department of Surgery
News
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News
- April 27, 2026
Personalized Chemotherapy for Abdominal Cancer: A Q&A with Kiran Turaga
- March 09, 2026
Yale Cancer Center Experts Present Advances in Cancer Research at Major Surgical Meeting
- October 14, 2025
Showcasing the Beauty of Basic Science
- February 05, 2024
Surgical Education Solutions: Grant Recipients Announced
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May 202619Tuesday
Organization Only Justin "Jay" Bader, MD - Shahyan Ur Rehman, MDZoom details sent via Outlook