2020
Impact of Body Mass Index on Outcomes of Autogenous Fistulas for Hemodialysis Access
Arhuidese I, Holscher C, Elemuo C, Parkerson G, Johnson B, Malas M. Impact of Body Mass Index on Outcomes of Autogenous Fistulas for Hemodialysis Access. Annals Of Vascular Surgery 2020, 68: 192-200. PMID: 32339695, DOI: 10.1016/j.avsg.2020.04.009.Peer-Reviewed Original ResearchConceptsBody mass indexImpact of body mass indexEnd-stage renal diseaseObesity class IObesity classAutogenous fistulasMass indexSpectrum of body mass indexPopulation-based cohort of patientsUnited States Renal Database SystemClass ILog-rank testCohort of patientsCox regression analysisPrevalence of obesityKaplan-Meier estimatesPopulation-based cohortTreatment of end-stage renal diseaseChi-square testAccess maturationNo significant differenceNormal weightRetrospective studyHemodialysis accessRenal diseaseAge-related outcomes of arteriovenous grafts for hemodialysis access
Arhuidese I, Beaulieu R, Aridi H, Locham S, Baldwin E, Malas M. Age-related outcomes of arteriovenous grafts for hemodialysis access. Journal Of Vascular Surgery 2020, 72: 643-650. PMID: 32067881, DOI: 10.1016/j.jvs.2019.10.096.Peer-Reviewed Original ResearchMeSH KeywordsAge FactorsAgedAged, 80 and overArteriovenous Shunt, SurgicalBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationDatabases, FactualDevice RemovalFemaleGraft Occlusion, VascularHumansKidney Failure, ChronicMaleMiddle AgedProsthesis-Related InfectionsRenal DialysisReoperationRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeVascular PatencyConceptsPrimary assisted patencyPopulation-based cohortGraft infectionAssisted patencySecondary patencyPrimary patencyNo significant differenceArteriovenous graftsHemodialysis accessOutcomes of arteriovenous graftsAge-related outcomesOlder age categoriesCohort of hemodialysis patientsProsthetic graft infectionArteriovenous graft placementEnd-stage renal diseaseLog-rank testPrevalence of end-stage renal diseaseKaplan-Meier analysisSignificant differenceCox regression analysisRetrospective cohort studyOlder ageGraft excisionU.S. Renal Data System
2019
Survival after major lower extremity amputation in patients with end-stage renal disease
Arhuidese I, Nejim B, Aji E, Canner J, Malas M. Survival after major lower extremity amputation in patients with end-stage renal disease. Journal Of Vascular Surgery 2019, 70: 1291-1298. PMID: 31543169, DOI: 10.1016/j.jvs.2018.12.055.Peer-Reviewed Original ResearchConceptsKnee amputeesKnee amputationBurden of peripheral artery diseaseLower extremity amputationEstimates of life expectancyEnd-stage renal diseaseRisk-adjusted mortalityAmputation levelExtremity amputationRace-specific differencesRT recipientsHealthcare providersPeripheral arterial diseaseHD patientsLong-term mortalityUnited States Renal Data SystemMedian survivalBKAKneeHispanicsLife expectancyRenal transplantationMLEAAmputationCardiovascular diseaseOutcomes of Infrainguinal Lower Extremity Bypass Are Superior in Kidney Transplant Recipients Than Patients with Dialysis
Nejim B, Hicks C, Arhuidese I, Locham S, Dakour-Aridi H, Malas M. Outcomes of Infrainguinal Lower Extremity Bypass Are Superior in Kidney Transplant Recipients Than Patients with Dialysis. Annals Of Vascular Surgery 2019, 63: 209-217. PMID: 31349053, DOI: 10.1016/j.avsg.2019.04.026.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalBlood Vessel Prosthesis ImplantationDatabases, FactualFemaleHumansKidney Failure, ChronicKidney TransplantationLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseaseProgression-Free SurvivalRenal DialysisRetrospective StudiesRisk FactorsSaphenous VeinTime FactorsVascular PatencyConceptsLower extremity bypassEnd-stage renal diseaseKT recipientsPrimary patencyDialysis therapyAmputation-free survivalKidney transplantationVascular Quality Initiative databaseRisk-adjusted hazardsKidney transplant recipientsPositive effects of KTRisk of mortalityEffects of KTRisk of amputationLower-extremity bypassSurgical outcomesTransplant recipientsBaseline characteristicsBypass proceduresDialysis patientsRenal diseaseComparative efficacyKT groupDT groupPatients
2018
Infrainguinal bypass surgery outcomes are worse in hemodialysis patients compared with patients with renal transplants
Arhuidese I, Nejim B, Locham S, Malas M. Infrainguinal bypass surgery outcomes are worse in hemodialysis patients compared with patients with renal transplants. Journal Of Vascular Surgery 2018, 69: 850-856. PMID: 30583904, DOI: 10.1016/j.jvs.2018.05.252.Peer-Reviewed Original ResearchMeSH KeywordsAgedBlood Vessel Prosthesis ImplantationDatabases, FactualFemaleHumansKidney Failure, ChronicKidney TransplantationLimb SalvageLower ExtremityMaleMiddle AgedPeripheral Arterial DiseasePostoperative ComplicationsRenal DialysisRetrospective StudiesRisk AssessmentRisk FactorsTime FactorsTreatment OutcomeUnited StatesVascular PatencyConceptsInfrainguinal bypass surgeryRenal transplantationRT patientsPatient survivalOutcome of infrainguinal bypass surgeryHD patientsBenefits of renal transplantationLimb salvageEnd-stage renal diseaseCox regression analysisLong-term outcomesEvaluate 30-dayRisk-adjusted analysisPopulation-based cohortCritical limb ischemiaU.S. Renal Data SystemRetrospective reviewBypass surgeryKaplan-MeierSurgery outcomesPatient-level riskRenal diseaseHemodialysis patientsLimb ischemiaPatientsA prospective randomized study of bovine carotid artery biologic graft and expanded polytetrafluoroethylene for permanent hemodialysis access
Dakour Aridi H, Arhuidese I, Scudder M, Reifsnyder T, Malas M. A prospective randomized study of bovine carotid artery biologic graft and expanded polytetrafluoroethylene for permanent hemodialysis access. Journal Of Vascular Surgery 2018, 67: 1606-1612.e4. PMID: 29567027, DOI: 10.1016/j.jvs.2017.12.058.Peer-Reviewed Original ResearchMeSH KeywordsAcademic Medical CentersAnimalsArteriovenous Shunt, SurgicalBaltimoreBlood Vessel ProsthesisCarotid ArteriesCattleClinical ProtocolsHeterograftsHumansKaplan-Meier EstimatePolytetrafluoroethyleneProportional Hazards ModelsProspective StudiesProsthesis DesignRenal DialysisResearch DesignTime FactorsTreatment OutcomeConceptsPermanent hemodialysis accessArteriovenous fistulaNative arteriovenous fistulaArteriovenous graftsBovine carotid arteryHemodialysis accessBiological graftsMultivariate Cox proportional regression analysisNational Kidney Foundation Kidney Disease Outcomes Quality Initiative guidelinesKidney Disease Outcomes Quality Initiative guidelinesKidney Foundation Kidney Disease Outcomes Quality Initiative guidelinesCox proportional regression analysisArteriovenous graft creationAVG placementEnd-stage renal diseasePrimary end pointTreatment of patientsVascular access patientsSynthetic arteriovenous graftsHistory of intoleranceYears of ageRandomized controlled trialsAcademic hospital centerReintervention rateFunctional patencyAggressive infrainguinal revascularization in renal transplant patients is justifiable
Craig-Schapiro R, Nejim B, Arhuidese I, Malas M. Aggressive infrainguinal revascularization in renal transplant patients is justifiable. American Journal Of Transplantation 2018, 18: 1718-1725. PMID: 29288558, DOI: 10.1111/ajt.14636.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmputation, SurgicalFemaleFollow-Up StudiesHumansKidney Failure, ChronicKidney TransplantationLimb SalvageLower ExtremityMaleMiddle AgedPatient SelectionPostoperative ComplicationsPrognosisReoperationRetrospective StudiesRisk AssessmentRisk FactorsSurvival RateTime FactorsVascular GraftingVascular PatencyConceptsCritical limb ischemiaRenal transplant patientsTransplant patientsNontransplant patientsLimb ischemiaPrimary patencyInfrainguinal revascularizationRisk factorsMultivariate Cox regression analysisVascular Quality Initiative databaseEnd-stage renal diseaseDistal bypassCox regression analysisOutcomes of lower extremity revascularizationPrimary patency lossLower extremity revascularizationAmputation-free survivalLimb salvage outcomesAssociated with limb lossOverall survivalProsthetic conduitVein conduitPatency lossRenal diseaseInfrainguinal bypass
2015
Early outcomes after elective colorectal surgery in end stage renal disease (ESRD) vs non-ESRD Patients
Arhuidese I, Malas M, Obeid T, Qazi U, Ahuja N, Efron J. Early outcomes after elective colorectal surgery in end stage renal disease (ESRD) vs non-ESRD Patients. Journal Of The American College Of Surgeons 2015, 221: e59. DOI: 10.1016/j.jamcollsurg.2015.08.052.Peer-Reviewed Original ResearchQuality Improvement Targets for Regional Variation in Surgical End-Stage Renal Disease Care
Zarkowsky DS, Hicks CW, Arhuidese I, Canner JK, Obeid T, Qazi U, Schneider E, Abularrage CJ, Black JH, Freischlag JA, Malas MB. Quality Improvement Targets for Regional Variation in Surgical End-Stage Renal Disease Care. JAMA Surgery 2015, 150: 764-770. PMID: 26107005, DOI: 10.1001/jamasurg.2015.1126.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseUS Renal Data SystemFirst hemodialysisNephrology careAVF accessMortality hazardEnd-stage renal disease careLogistic regressionCongestive heart failureRenal replacement therapyMultivariable logistic regressionArteriovenous fistula accessQuality improvement targetsPatient comorbiditiesHeart failurePatient characteristicsRenal diseaseDisease careESRD mortalityReplacement therapyFistula accessUnivariate analysisRetrospective analysisBest practice guidelinesMAIN OUTCOMEVascular access modifies the protective effect of obesity on survival in hemodialysis patients
Arhuidese I, Obeid T, Hicks C, Qazi U, Botchey I, Zarkowsky D, Reifsnyder T, Malas M. Vascular access modifies the protective effect of obesity on survival in hemodialysis patients. Surgery 2015, 158: 1628-1634. PMID: 26126794, DOI: 10.1016/j.surg.2015.04.036.Peer-Reviewed Original ResearchConceptsBody mass indexEnd-stage renal diseaseNormal body mass indexProtective effect of obesityHigher body mass indexEffect of obesityObesity paradoxProtective effect of increasing BMIEffect of increased BMIBody mass index statusMass indexHD accessProtective effectAssociated with lower mortalityPropensity score matching analysisSurvival of patientsScore matching analysisSurvival benefitImproved survivalRetrospective studyHemodialysis accessInitiate hemodialysisPatient backgroundRenal diseaseCox regressionRacial/Ethnic Disparities Associated With Initial Hemodialysis Access
Zarkowsky DS, Arhuidese IJ, Hicks CW, Canner JK, Qazi U, Obeid T, Schneider E, Abularrage CJ, Freischlag JA, Malas MB. Racial/Ethnic Disparities Associated With Initial Hemodialysis Access. JAMA Surgery 2015, 150: 529-536. PMID: 25923973, DOI: 10.1001/jamasurg.2015.0287.Peer-Reviewed Original ResearchConceptsMedical insurance statusEnd-stage renal diseaseUS Renal Data SystemInitial hemodialysis accessWhite patientsArteriovenous fistulaBlack patientsHispanic patientsRace/ethnicityNephrology careInsurance statusRenal diseaseHemodialysis accessChronic obstructive pulmonary diseaseLogistic regressionMore white patientsInfluence of comorbiditiesObstructive pulmonary diseaseRacial/Ethnic DisparitiesCoronary artery diseaseCategory of patientsMultivariable logistic regressionPatterns of utilizationDifferent races/ethnicitiesFistula utilizationTrends in Incident Hemodialysis Access and Mortality
Malas MB, Canner JK, Hicks CW, Arhuidese IJ, Zarkowsky DS, Qazi U, Schneider EB, Black JH, Segev DL, Freischlag JA. Trends in Incident Hemodialysis Access and Mortality. JAMA Surgery 2015, 150: 441-448. PMID: 25738981, DOI: 10.1001/jamasurg.2014.3484.Peer-Reviewed Original ResearchConceptsEnd-stage renal diseaseHemodialysis cathetersArteriovenous fistulaArteriovenous graftsLower mortalityRenal diseaseVascular accessHD outcomesNational Kidney Foundation Kidney Disease Outcomes Quality InitiativeKidney Foundation Kidney Disease Outcomes Quality InitiativeMultivariable Cox proportional hazards modelsPrior renal replacement therapyUS Renal Data SystemCox proportional hazards modelArteriovenous fistula useIncident HD patientsInitiation of hemodialysisRetrospective cohort studyRenal replacement therapyProportional hazards modelFistula useCohort studySurvival benefitHD patientsPropensity score-matching technique