2021
Uncertainty in tissue equivalent proportional counter assessments of microdosimetry and RBE estimates in carbon radiotherapy
Hartzell S, Guan F, Taylor P, Peterson C, Taddei P, Kry S. Uncertainty in tissue equivalent proportional counter assessments of microdosimetry and RBE estimates in carbon radiotherapy. Physics In Medicine And Biology 2021, 66: 155018. PMID: 34252894, DOI: 10.1088/1361-6560/ac1366.Peer-Reviewed Original ResearchConceptsTissue equivalent proportional counterCommon mathematical modelPerturbed valuesMicrodosimetric kinetic modelLow-energy cutMonte Carlo toolkitMathematical modelCounting statisticsCentral beam axisEnergy deposition distributionsStatistic uncertaintyInput parametersTherapeutic carbon beamsLineal energy valuesCarbon beamBeam axisTEPC measurementsSources of uncertaintyWall effectsModel input parametersMicrodosimetric spectraInherent uncertaintyRelative biological effectivenessUncertaintyCarbon radiotherapy
2017
Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams
Patel D, Bronk L, Guan F, Peeler CR, Brons S, Dokic I, Abdollahi A, Rittmüller C, Jäkel O, Grosshans D, Mohan R, Titt U. Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams. Medical Physics 2017, 44: 6061-6073. PMID: 28880368, DOI: 10.1002/mp.12568.Peer-Reviewed Original ResearchMeSH KeywordsCell Line, TumorHumansMonte Carlo MethodRadiometryRelative Biological EffectivenessUncertainty