2023
Dosimetric response of Gafchromic™ EBT‐XD film to therapeutic protons
Guan F, Wang X, Yang M, Draeger E, Han D, Iga K, Guo F, Perles L, Li Y, Sahoo N, Mohan R, Chen Z. Dosimetric response of Gafchromic™ EBT‐XD film to therapeutic protons. Precision Radiation Oncology 2023, 7: 15-26. PMID: 37868341, PMCID: PMC10586355, DOI: 10.1002/pro6.1187.Peer-Reviewed Original ResearchLinear energy transferEBT-XD filmsTherapeutic protonsFilm calibrationProton linear energy transferUltra-high Dose Rate FLASH RadiotherapyDynamic dose rangeMV photon beamDose-averaged LET valuesDose rate dependenceProton beamlineProton beamPhoton beamsFLASH beamSpot scanning proton beamsDosimetric responseLET dependenceFLASH radiotherapyHigh-dose applicationFilm responseLET valuesEnergy transferBeamProtonsGafchromic
2022
Roadmap: helium ion therapy
Mairani A, Mein S, Blakely E, Debus J, Durante M, Ferrari A, Fuchs H, Georg D, Grosshans DR, Guan F, Haberer T, Harrabi S, Horst F, Inaniwa T, Karger CP, Mohan R, Paganetti H, Parodi K, Sala P, Schuy C, Tessonnier T, Titt U, Weber U. Roadmap: helium ion therapy. Physics In Medicine And Biology 2022, 67: 15tr02. PMID: 35395649, DOI: 10.1088/1361-6560/ac65d3.Peer-Reviewed Original ResearchConceptsHelium ion beamHeavy ion therapyIon beam therapyHelium ionsIon beamIon therapyRelative biological effectivenessHeavy ion beamsLawrence Berkeley National LaboratoryCarbon ion beamsHelium ion therapyDifferent particle speciesBerkeley National LaboratoryClinical proton beamsCarbon ion therapyLinear energy transferHigh relative biological effectivenessSharp lateral penumbraHigh penetration depthLateral scatteringNeon ionsBeam therapyProton beamParticle speciesTerms of physics
2018
Physical parameter optimization scheme for radiobiological studies of charged particle therapy
Geng C, Gates D, Bronk L, Ma D, Guan F. Physical parameter optimization scheme for radiobiological studies of charged particle therapy. Physica Medica 2018, 51: 13-21. PMID: 30278981, PMCID: PMC6173200, DOI: 10.1016/j.ejmp.2018.06.001.Peer-Reviewed Original ResearchConceptsIon beamParticle therapyPhysical quantitiesDose-averaged linear energy transferC-ion beamsLinear energy transferBiological dose optimizationParticle beamsProton beamBragg curveBragg peakWhole target regionBeamCorresponding physical dataEnergy transferProtonsMonte Carlo simulationsAppropriate biophysical modelSpatial distributionSOBPRadiobiological studiesCarlo simulationsDose spreadIonsLET
2017
Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams
Patel D, Bronk L, Guan F, Peeler CR, Brons S, Dokic I, Abdollahi A, Rittmüller C, Jäkel O, Grosshans D, Mohan R, Titt U. Optimization of Monte Carlo particle transport parameters and validation of a novel high throughput experimental setup to measure the biological effects of particle beams. Medical Physics 2017, 44: 6061-6073. PMID: 28880368, DOI: 10.1002/mp.12568.Peer-Reviewed Original Research
2014
TH‐A‐19A‐05: Modeling Physics Properties and Biologic Effects Induced by Proton and Helium Ions
Taleei R, Titt U, Peeler C, Guan F, Mirkovic D, Grosshans D, Mohan R. TH‐A‐19A‐05: Modeling Physics Properties and Biologic Effects Induced by Proton and Helium Ions. Medical Physics 2014, 41: 534-534. DOI: 10.1118/1.4889538.Peer-Reviewed Original ResearchMonte Carlo codeFragmentation cross sectionsHelium ionsBragg peakCarlo codeCross sectionsGeneral purpose Monte Carlo codeLight ionsMicrodosimetric parametersProton beamEnergy spectrumCarbon ionsBragg curveDepth dosePhysics propertiesWater phantomPhysical propertiesRBE increasesProtonsMonte Carlo simulationsDose distributionFLUKABeamIonsCurve calculations
2013
SU‐E‐T‐48: Relative Proton Stopping Power Ratio Database for Common Dosimetry Phantom Materials
Kerr M, Dhanesar S, Guan F, Taylor M, Zhu X, Gillin M, Amos R, Sahoo N. SU‐E‐T‐48: Relative Proton Stopping Power Ratio Database for Common Dosimetry Phantom Materials. Medical Physics 2013, 40: 214-214. DOI: 10.1118/1.4814483.Peer-Reviewed Original Research