2019
Using the Proton Energy Spectrum and Microdosimetry to Model Proton Relative Biological Effectiveness
Newpower M, Patel D, Bronk L, Guan F, Chaudhary P, McMahon SJ, Prise KM, Schettino G, Grosshans DR, Mohan R. Using the Proton Energy Spectrum and Microdosimetry to Model Proton Relative Biological Effectiveness. International Journal Of Radiation Oncology • Biology • Physics 2019, 104: 316-324. PMID: 30731186, PMCID: PMC6499683, DOI: 10.1016/j.ijrobp.2019.01.094.Peer-Reviewed Original ResearchConceptsProton energy spectraMicrodosimetric kinetic modelDose-mean lineal energyRelative biological effectivenessProton irradiation experimentsEnergy spectrumLineal energyLineal energy yIrradiation experimentsLineal energy distributionsDose-averaged linear energy transferBiological effectivenessDifferent proton energiesLinear energy transferRBE modelsProton energyBragg curveEnergy distributionGeant4-DNAProton irradiationRBE data
2016
Monte Carlo simulations of 3He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness
Taleei R, Guan F, Peeler C, Bronk L, Patel D, Mirkovic D, Grosshans DR, Mohan R, Titt U. Monte Carlo simulations of 3He ion physical characteristics in a water phantom and evaluation of radiobiological effectiveness. Medical Physics 2016, 43: 761-776. PMID: 26843239, DOI: 10.1118/1.4939440.Peer-Reviewed Original ResearchConceptsMonte Carlo codeEnergy depositionCarlo codeLineal energyEnergy distributionRadiation beam qualitiesSecondary particle productionDifferent Monte Carlo codesDepth dose curvesPrimary beam parametersGaussian energy distributionMonte Carlo systemHelium ionsBeam qualityMicrodosimetric parametersMonte Carlo methodBeam parametersEnergy spectrumIncident beamBragg curveRadiobiological effectivenessBragg peakHalf maximumProton doseFull width