Shuangshuang Du
she/her/hers
About
Research
Publications
2026
Fibroblast depletion reveals mammalian epithelial resilience across neonatal and adult stages
Gaeta I, Du S, Villeneuve C, Gonzalez D, Matte-Martone C, Ganesan S, Simpson D, Tibebu H, Moore J, Kam C, Gallini S, Wei H, Bertillot F, Zeuschner D, Gonzalez L, Rana U, Sumigray K, Wickström S, Greco V. Fibroblast depletion reveals mammalian epithelial resilience across neonatal and adult stages. Journal Of Cell Biology 2026, 225: e202507165. PMID: 42283726, PMCID: PMC13267860, DOI: 10.1083/jcb.202507165.Peer-Reviewed Original ResearchConceptsepidermal stem cell proliferationstem cell proliferationfibroblasts depletedepidermal stem cell compartmentproliferation of epidermal stem cellsstem cell compartmentniche-stem cell interactionscell proliferationcollagen I densitydifferentiation in vivoepidermal stem cellsstage in vivoprotective barrier functionregenerative programstem cellsbarrier functionstem cell behaviorcell interactionsfunctional capacityregenerative organcell compartmentskin fibroblastscellular turnovercompensatory mechanismsfibroblast density
2024
Correction: Cell cycle controls long-range calcium signaling in the regenerating epidermis
Moore J, Bhaskar D, Gao F, Matte-Martone C, Du S, Lathrop E, Ganesan S, Shao L, Norris R, Sanz N, Annusver K, Kasper M, Cox A, Hendry C, Rieck B, Krishnaswamy S, Greco V. Correction: Cell cycle controls long-range calcium signaling in the regenerating epidermis. Journal Of Cell Biology 2024, 223: e20230209503052024c. PMID: 38477880, PMCID: PMC10938063, DOI: 10.1083/jcb.20230209503052024c.Commentaries, Editorials and Letters
2023
Organ function is preserved despite reorganization of niche architecture in the hair follicle
Wei H, Du S, Parksong J, Pasolli H, Matte-Martone C, Regot S, Gonzalez L, Xin T, Greco V. Organ function is preserved despite reorganization of niche architecture in the hair follicle. Cell Stem Cell 2023, 30: 962-972.e6. PMID: 37419106, PMCID: PMC10362479, DOI: 10.1016/j.stem.2023.06.003.Peer-Reviewed Original ResearchConceptsniche architecturedermal papilla fibroblastsdifferentiated lineageshair follicle growthstereotypic architecturemultipotent progenitorsepithelial progenitorsfunctional importancenichestem cellsfibroblast nicheprogenitorspowerful modelintravital imagingdermal papillafibroblastshair folliclesfollicle growthorgan functionlineagesdifferentiationcrosstalkhairproliferationcellsCell cycle controls long-range calcium signaling in the regenerating epidermis
Moore J, Bhaskar D, Gao F, Matte-Martone C, Du S, Lathrop E, Ganesan S, Shao L, Norris R, Sanz N, Annusver K, Kasper M, Cox A, Hendry C, Rieck B, Krishnaswamy S, Greco V. Cell cycle controls long-range calcium signaling in the regenerating epidermis. Journal Of Cell Biology 2023, 222: e202302095. PMID: 37102999, PMCID: PMC10140546, DOI: 10.1083/jcb.202302095.Peer-Reviewed Original Research
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Nathan Smith Building
315 Cedar Street
New Haven, CT 06510