Charla Nich
Manager PsychiatryCards
About
Research
Publications
Featured Publications
Racial and ethnic differences in alcohol, cannabis, and illicit substance use treatment: a systematic review and narrative synthesis of studies done in the USA
Jordan A, Quainoo S, Nich C, Babuscio TA, Funaro MC, Carroll KM. Racial and ethnic differences in alcohol, cannabis, and illicit substance use treatment: a systematic review and narrative synthesis of studies done in the USA. The Lancet Psychiatry 2022, 9: 660-675. PMID: 35752192, DOI: 10.1016/s2215-0366(22)00160-2.Peer-Reviewed Original ResearchConceptsSubstance use outcomesTreatment initiationJoanna Briggs Institute appraisal toolsSystematic reviewSubstance use disordersSignificant differencesSubstance use treatmentDissemination of treatmentUncontrolled trialsClinical trialsBaseline differencesStudy qualityInclusion criteriaUse disordersRCTsNarrative synthesisSocial determinantsUse treatmentAppraisal toolLatinx adultsEthnic differencesEthnic populationsOutcomesTrialsLatinx populations
2024
Promoting Race and Ethnic Diversity in a Hospital-Based Randomized Clinical Trial to Address Untreated Alcohol Use Disorder: Initial Lessons Learned.
Edelman E, Frankforter T, Rojas-Perez O, Ablondi K, Castro C, Corvino J, Garcia I, Gordon D, Jaramillo Y, Johnson N, Jordan A, Nich C, Paris M, Pagano D, Weimer M, Williams E, Kiluk B. Promoting Race and Ethnic Diversity in a Hospital-Based Randomized Clinical Trial to Address Untreated Alcohol Use Disorder: Initial Lessons Learned. Journal Of Addiction Medicine 2024 PMID: 39514895, DOI: 10.1097/adm.0000000000001400.Peer-Reviewed Original ResearchAlcohol use disorderBrief Negotiation InterviewUntreated alcohol use disorderUse disorderSocial determinants of healthCognitive behavioral therapyElectronic medical record dataDeterminants of healthEthnically diverse sampleMedical record dataMonths of recruitmentBehavioral therapyModifications-EnhancedReporting AdaptationsTreatment engagementEffectiveness of strategiesSocial determinantsInitiation of medicationRecruitment approachesDiverse samplePost-hospitalizationAlcohol useResearch staffParent trialRecord dataImprovement in coping skills from culturally-adapted digital CBT for Spanish-speaking Hispanics with substance use disorder: Secondary analysis of a randomized clinical trial
Benitez B, Loya J, Jaramillo Y, Muro-Rodriguez N, Rojas Perez O, Nich C, Frankforter T, Paris M, Kiluk B. Improvement in coping skills from culturally-adapted digital CBT for Spanish-speaking Hispanics with substance use disorder: Secondary analysis of a randomized clinical trial. Journal Of Substance Use And Addiction Treatment 2024, 168: 209536. PMID: 39374899, DOI: 10.1016/j.josat.2024.209536.Peer-Reviewed Original ResearchMechanisms of cognitive behavioral therapyQuality of coping skillsCognitive behavioral therapySubstance use disordersPrimary substance useCoping skillsSubstance useCBT programOutpatient treatmentWeeks of outpatient treatmentDigital cognitive behavioral therapyMechanisms of behavior changeWithin-person increasesDaily substance useAdaptive coping skillsSecondary analysis of clinical trial dataTreatment mechanismsRandomized to 8Associated with reductionsBehavioral therapyAnalysis of clinical trial dataUse disorderGeneralizability of researchSecondary analysisSpanish-speaking Hispanic adultsA Digital Cognitive Behavioral Therapy Program for Adults With Alcohol Use Disorder
Kiluk B, Benitez B, DeVito E, Frankforter T, LaPaglia D, O’Malley S, Nich C. A Digital Cognitive Behavioral Therapy Program for Adults With Alcohol Use Disorder. JAMA Network Open 2024, 7: e2435205. PMID: 39325452, PMCID: PMC11428014, DOI: 10.1001/jamanetworkopen.2024.35205.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyDigital cognitive behavioral therapyAlcohol use disorderAlcohol useCBT programUse disorderCognitive behavioral therapy programCurrent alcohol use disorderTreatment-seeking adultsBehavioral therapy programEvidence-based treatmentsBaseline to 6-month follow-upRates of alcohol useReducing alcohol useTreatment periodRandomized clinical trialsBehavioral therapyOutpatient substancePercentage of daysOutpatient treatmentIntention-to-treat analysisIndividual counselingStudy periodFollow-upIntention-to-treatMeasurement invariance of the Perceived Stress Scale across race, sex, and time, and differential impacts on cocaine use treatment outcomes
Schick M, Kiluk B, Nich C, LaPaglia D, Haeny A. Measurement invariance of the Perceived Stress Scale across race, sex, and time, and differential impacts on cocaine use treatment outcomes. Journal Of Substance Use And Addiction Treatment 2024, 166: 209493. PMID: 39151798, PMCID: PMC11392621, DOI: 10.1016/j.josat.2024.209493.Peer-Reviewed Original ResearchCocaine use disorderPerceived Stress ScaleTreatment retentionMeasurement invarianceTreatment outcomesSubstance use treatment outcomesStress ScalePredicting treatment retentionSelf-efficacyCoping self-efficacyTwo-factor modelInfluence treatment outcomeCocaine abuse/dependenceDSM-IVUse disorderCocaine useBetween-group differencesMetric invarianceScalar invarianceTwo-factorCocainePharmacological treatmentFactor analysisDifferential impactAbuse/dependenceT166 Treatment Outcomes From Computerized CBT for Substance Use Disorders Among People With Criminal Justice Involvement
Loya J, Babuscio T, Nich C, Kiluk B. T166 Treatment Outcomes From Computerized CBT for Substance Use Disorders Among People With Criminal Justice Involvement. Drug And Alcohol Dependence 2024, 260: 110615. DOI: 10.1016/j.drugalcdep.2023.110615.Peer-Reviewed Original ResearchStructural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment
McCurdy L, DeVito E, Loya J, Nich C, Zhai Z, Kiluk B, Potenza M. Structural brain changes associated with cocaine use and digital cognitive behavioral therapy in cocaine use disorder treatment. Drug And Alcohol Dependence Reports 2024, 11: 100246. PMID: 38966567, PMCID: PMC11222934, DOI: 10.1016/j.dadr.2024.100246.Peer-Reviewed Original ResearchCocaine use disorderCognitive behavioral therapyCocaine useBehavioral therapyBrain changesBrain structuresWhole-brain voxel-based morphometry analysisCocaine use disorder treatmentLevel of cocaine useWeeks of outpatient treatmentVoxel-based morphometry analysisDigital cognitive behavioral therapyT1-weighted magnetic resonance imaging scansRight caudate bodyAssociated with cocaine useMethadone-maintained individualsGray matter volumeStructural brain changesFunction of engagementCaudate bodyRight caudateCUD treatmentMatter volumeUse disorderBilateral cerebellumCognitive processing therapy (CPT) versus individual drug counseling (IDC) for PTSD for veterans with opioid use disorder maintained on buprenorphine
Petrakis I, Meshberg‐Cohen S, Nich C, Kelly M, Claudio T, Jane J, Pisani E, Ralevski E. Cognitive processing therapy (CPT) versus individual drug counseling (IDC) for PTSD for veterans with opioid use disorder maintained on buprenorphine. American Journal On Addictions 2024, 33: 525-533. PMID: 38624259, DOI: 10.1111/ajad.13557.Peer-Reviewed Original ResearchCognitive processing therapyIndividual drug counselingPosttraumatic stress disorderOpioid use disorderSubstance use disordersDrug counselingProcessing therapyPTSD symptomsUse disorderCognitive processing therapy groupEvidence-based trauma-focused psychotherapiesSelf-reported PTSD symptomsPosttraumatic stress disorder symptomsPosttraumatic stress disorder treatmentRemission of PTSD symptomsPosttraumatic Stress Disorder ChecklistComorbid opioid use disorderTrauma-focused psychotherapyTrauma-focused treatmentRates of comorbidityTreatment group differencesPCL-5Stress disorderGroup differencesRandomized clinical trialsEfficacy of Integrating the Management of Pain and Addiction via Collaborative Treatment (IMPACT) in Individuals With Chronic Pain and Opioid Use Disorder: Protocol for a Randomized Clinical Trial of a Digital Cognitive Behavioral Treatment
MacLean R, Ankawi B, Driscoll M, Gordon M, Frankforter T, Nich C, Szollosy S, Loya J, Brito L, Ribeiro M, Edmond S, Becker W, Martino S, Sofuoglu M, Heapy A. Efficacy of Integrating the Management of Pain and Addiction via Collaborative Treatment (IMPACT) in Individuals With Chronic Pain and Opioid Use Disorder: Protocol for a Randomized Clinical Trial of a Digital Cognitive Behavioral Treatment. JMIR Research Protocols 2024, 13: e54342. PMID: 38506917, PMCID: PMC10993119, DOI: 10.2196/54342.Peer-Reviewed Original Research
2023
The connection still matters: Therapeutic alliance with digital treatment for alcohol use disorder
Benitez B, Frankforter T, Nich C, Kiluk B. The connection still matters: Therapeutic alliance with digital treatment for alcohol use disorder. Alcohol Clinical And Experimental Research 2023, 47: 2197-2207. PMID: 38226756, PMCID: PMC10792249, DOI: 10.1111/acer.15199.Peer-Reviewed Original ResearchWorking Alliance InventoryAlliance ratingsAlcohol useMinimal clinical monitoringOutpatient AUD treatmentPatient-reported measuresAlcohol use disorderDisorder treatment outcomesDaily alcohol useCognitive behavioral therapy programBehavioral therapy programAlcohol use disorder treatment outcomesClinical trialsTreatment outcomesFuture drinkingUse disordersTreatment efficacyTreatment sessionsAUD treatmentClinical monitoringComputerized cognitive behavioural therapy programmeTherapy programFuture alcohol useTherapeutic allianceAlliance Inventory
News
News
- September 26, 2024
Yale Study: Digital Cognitive Behavioral Therapy Program Found More Effective Than Clinician-Delivered Therapy at Reducing Alcohol Use in a Clinical Trial
- May 30, 2023
Kathy Carroll Honored with New Playground in Newhallville
- May 23, 2023Source: Journal of Substance Use and Addiction Treatment
Breaking Through Social Determinants of Health: Imani Breakthrough
- December 06, 2022
Giving to Others a Holiday Tradition at Yale Psychotherapy Development Center