Charla Nich
Manager PsychiatryCards
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Research
Publications
Featured Publications
Racial and ethnic differences in alcohol, cannabis, and illicit substance use treatment: a systematic review and narrative synthesis of studies done in the USA
Jordan A, Quainoo S, Nich C, Babuscio TA, Funaro MC, Carroll KM. Racial and ethnic differences in alcohol, cannabis, and illicit substance use treatment: a systematic review and narrative synthesis of studies done in the USA. The Lancet Psychiatry 2022, 9: 660-675. PMID: 35752192, DOI: 10.1016/s2215-0366(22)00160-2.Peer-Reviewed Original ResearchConceptsSubstance use outcomesTreatment initiationJoanna Briggs Institute appraisal toolsSystematic reviewSubstance use disordersSignificant differencesSubstance use treatmentDissemination of treatmentUncontrolled trialsClinical trialsBaseline differencesStudy qualityInclusion criteriaUse disordersRCTsNarrative synthesisSocial determinantsUse treatmentAppraisal toolLatinx adultsEthnic differencesEthnic populationsOutcomesTrialsLatinx populations
2025
Comparing content within a culturally-adapted digital treatment for Hispanic patients with alcohol use disorder
Benitez B, Frankforter T, Nich C, Paris M, Kiluk B. Comparing content within a culturally-adapted digital treatment for Hispanic patients with alcohol use disorder. Npj Digital Medicine 2025, 9: 23. PMID: 41361015, PMCID: PMC12783792, DOI: 10.1038/s41746-025-02197-7.Peer-Reviewed Original ResearchAlcohol use disorderCognitive restructuringUse disorderCognitive behavioral therapy programBehavioral therapy programDigital therapeuticsNon-Hispanic White peopleTherapy programTreatment accessDigital treatmentAlcohol-related harmHispanic peopleDisordersAlcohol-related health outcomesClinical trialsParticipantsHealth outcomesAlcoholCravingHispanic patientsWhite peopleRandom orderPeopleDecision makingTreatmentCorrection: Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications and CBT4CBT: protocol for a randomized clinical trial in a diverse patient population
Edelman E, Rojas-Perez O, Nich C, Corvino J, Frankforter T, Gordon D, Jordan A, Paris, Jr M, Weimer M, Yates B, Williams E, Kiluk B. Correction: Promoting alcohol treatment engagement post-hospitalization with brief intervention, medications and CBT4CBT: protocol for a randomized clinical trial in a diverse patient population. Addiction Science & Clinical Practice 2025, 20: 29. PMID: 40128914, PMCID: PMC11931771, DOI: 10.1186/s13722-025-00558-x.Peer-Reviewed Original ResearchStructural Brain Changes Associated With Cognitive Behavioral Therapy in Cocaine Use Disorder Treatment
McCurdy L, DeVito E, Loya J, Nich C, Kiluk B, Potenza M. Structural Brain Changes Associated With Cognitive Behavioral Therapy in Cocaine Use Disorder Treatment. Drug And Alcohol Dependence 2025, 267: 112224. DOI: 10.1016/j.drugalcdep.2024.112224.Peer-Reviewed Original ResearchT124 Changes in Risk-Taking Among People Who Received Cognitive Behavioral Therapy Versus an Other Treatment for Substance Use
Loya J, Babuscio T, Nich C, Kiluk B. T124 Changes in Risk-Taking Among People Who Received Cognitive Behavioral Therapy Versus an Other Treatment for Substance Use. Drug And Alcohol Dependence 2025, 267: 111892. DOI: 10.1016/j.drugalcdep.2024.111892.Peer-Reviewed Original Research
2024
Promoting Race and Ethnic Diversity in a Hospital-Based Randomized Clinical Trial to Address Untreated Alcohol Use Disorder: Initial Lessons Learned
Edelman E, Frankforter T, Rojas-Perez O, Ablondi K, Castro C, Corvino J, Garcia I, Gordon D, Jaramillo Y, Johnson N, Jordan A, Nich C, Paris M, Pagano D, Weimer M, Williams E, Kiluk B. Promoting Race and Ethnic Diversity in a Hospital-Based Randomized Clinical Trial to Address Untreated Alcohol Use Disorder: Initial Lessons Learned. Journal Of Addiction Medicine 2024, 19: 334-337. PMID: 39514895, PMCID: PMC12178687, DOI: 10.1097/adm.0000000000001400.Peer-Reviewed Original ResearchAlcohol use disorderBrief Negotiation InterviewUntreated Alcohol Use DisorderUse disorderSocial determinants of healthCognitive behavioral therapyElectronic medical record dataDeterminants of healthEthnically diverse sampleMedical record dataMonths of recruitmentBehavioral therapyModifications-EnhancedReporting AdaptationsTreatment engagementEffectiveness of strategiesSocial determinantsInitiation of medicationRecruitment approachesDiverse samplePost-hospitalizationAlcohol useResearch staffParent trialRecord dataImprovement in coping skills from culturally-adapted digital CBT for Spanish-speaking Hispanics with substance use disorder: Secondary analysis of a randomized clinical trial
Benitez B, Loya J, Jaramillo Y, Muro-Rodriguez N, Rojas Perez O, Nich C, Frankforter T, Paris M, Kiluk B. Improvement in coping skills from culturally-adapted digital CBT for Spanish-speaking Hispanics with substance use disorder: Secondary analysis of a randomized clinical trial. Journal Of Substance Use And Addiction Treatment 2024, 168: 209536. PMID: 39374899, PMCID: PMC11624081, DOI: 10.1016/j.josat.2024.209536.Peer-Reviewed Original ResearchMechanisms of cognitive behavioral therapyQuality of coping skillsCognitive behavioral therapySubstance use disordersPrimary substance useCoping skillsSubstance useCBT programOutpatient treatmentWeeks of outpatient treatmentDigital cognitive behavioral therapyMechanisms of behavior changeWithin-person increasesDaily substance useAdaptive coping skillsSecondary analysis of clinical trial dataTreatment mechanismsRandomized to 8Associated with reductionsBehavioral therapyAnalysis of clinical trial dataUse disorderGeneralizability of researchSecondary analysisSpanish-speaking Hispanic adultsA Digital Cognitive Behavioral Therapy Program for Adults With Alcohol Use Disorder
Kiluk B, Benitez B, DeVito E, Frankforter T, LaPaglia D, O’Malley S, Nich C. A Digital Cognitive Behavioral Therapy Program for Adults With Alcohol Use Disorder. JAMA Network Open 2024, 7: e2435205. PMID: 39325452, PMCID: PMC11428014, DOI: 10.1001/jamanetworkopen.2024.35205.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyDigital cognitive behavioral therapyAlcohol use disorderAlcohol useCBT programUse disorderCognitive behavioral therapy programCurrent alcohol use disorderTreatment-seeking adultsBehavioral therapy programEvidence-based treatmentsBaseline to 6-month follow-upRates of alcohol useReducing alcohol useTreatment periodRandomized clinical trialsBehavioral therapyOutpatient substancePercentage of daysOutpatient treatmentIntention-to-treat analysisIndividual counselingStudy periodFollow-upIntention-to-treatMeasurement invariance of the Perceived Stress Scale across race, sex, and time, and differential impacts on cocaine use treatment outcomes
Schick M, Kiluk B, Nich C, LaPaglia D, Haeny A. Measurement invariance of the Perceived Stress Scale across race, sex, and time, and differential impacts on cocaine use treatment outcomes. Journal Of Substance Use And Addiction Treatment 2024, 166: 209493. PMID: 39151798, PMCID: PMC11392621, DOI: 10.1016/j.josat.2024.209493.Peer-Reviewed Original ResearchCocaine use disorderPerceived Stress ScaleTreatment retentionMeasurement invarianceTreatment outcomesSubstance Use Treatment OutcomesStress ScalePredicting treatment retentionSelf-EfficacyCoping self-efficacyTwo-factor modelInfluence treatment outcomeCocaine abuse/dependenceDSM-IVUse disorderCocaine useBetween-group differencesMetric invarianceScalar invarianceTwo-factorCocainePharmacological treatmentFactor analysisDifferential impactAbuse/dependenceT166 Treatment Outcomes From Computerized CBT for Substance Use Disorders Among People With Criminal Justice Involvement
Loya J, Babuscio T, Nich C, Kiluk B. T166 Treatment Outcomes From Computerized CBT for Substance Use Disorders Among People With Criminal Justice Involvement. Drug And Alcohol Dependence 2024, 260: 110615. DOI: 10.1016/j.drugalcdep.2023.110615.Peer-Reviewed Original Research
Academic Achievements & Community Involvement
News
News
- July 14, 2025
Department of Psychiatry Honors Residents, Fellows, Faculty, Staff at 2025 Annual Commencement Ceremonies
- September 26, 2024
Yale Study: Digital Cognitive Behavioral Therapy Program Found More Effective Than Clinician-Delivered Therapy at Reducing Alcohol Use in a Clinical Trial
- May 30, 2023
Kathy Carroll Honored with New Playground in Newhallville
- May 23, 2023Source: Journal of Substance Use and Addiction Treatment
Breaking Through Social Determinants of Health: Imani Breakthrough
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