1989
Pharmacological characterization of the receptor mediating electrophysiological responses to dopamine in the rat medial prefrontal cortex: a microiontophoretic study.
Sesack S, Bunney B. Pharmacological characterization of the receptor mediating electrophysiological responses to dopamine in the rat medial prefrontal cortex: a microiontophoretic study. Journal Of Pharmacology And Experimental Therapeutics 1989, 248: 1323-33. PMID: 2564893.Peer-Reviewed Original ResearchConceptsRat medial prefrontal cortexMedial prefrontal cortexGamma-aminobutyric acidD2-selective agonistsSelective agonistPrefrontal cortexPFC neuronsInhibitory effectSelective antagonistExtracellular single-unit recordingsD1-selective agonistsSingle-unit recordingsD1-selective antagonistD2-selective antagonistWeak antagonist activityMicroiontophoretic studyMicroiontophoretic techniquesSuperficial laminaeIontophoretic applicationLY171555Pharmacological characterizationInhibitory responsesMajority of cellsPharmacological characteristicsPharmacological profile
1987
Electrophysiological studies on the specificity of the cholecystokinin antagonist proglumide
Chiodo L, Freeman A, Bunney B. Electrophysiological studies on the specificity of the cholecystokinin antagonist proglumide. Brain Research 1987, 410: 205-211. PMID: 3036308, DOI: 10.1016/0006-8993(87)90317-9.Peer-Reviewed Original ResearchConceptsExcitatory effectsInhibitory effectA9 DA neuronsCCK receptor blockadeSelective CCK antagonistsMidbrain dopamine cellsPrefrontal cortical neuronsInhibitory potencyDA neuronsReceptor blockadeChronic treatmentSensorimotor cortexCCK antagonistsC-terminal octapeptideDA cellsSubstance PAPO effectsCortical neuronsDopamine cellsIntravenous administrationSelective antagonistRat CNSProglumideElectrophysiological studiesCholecystokinin