Joshua Bilsborrow, MD, MHS
Assistant Professor of Medicine (Rheumatology, Allergy & Immunology)DownloadHi-Res Photo
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Appointments
Rheumatology
Primary
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Contact Info
Appointments
Rheumatology
Primary
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Contact Info
Appointments
Rheumatology
Primary
Additional Titles
Affiliated Faculty, Yale Institute for Global Health
Contact Info
About
Titles
Assistant Professor of Medicine (Rheumatology, Allergy & Immunology)
Affiliated Faculty, Yale Institute for Global Health
Biography
Dr. Bilsborrow completed his MD at Vanderbilt University School of Medicine. He completed his residency in internal medicine at Yale-New Haven Hospital in 2016. Dr. Bilsborrow then joined the section of Yale Rheumatology, Allergy and Immunology for his fellowship training in 2016 and is currently doing research with Dr. Richard Bucala. His current research involves the isolation and characterization of the memory T cell subsets involved in rheumatoid arthritis and osteoarthritis. He is also interested in global health and rheumatology education and expansion in developing countries in particular.
Appointments
Rheumatology
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- MHS
- Yale University School of Medicine (2020)
- Resident
- Yale-New Haven Hospital (2016)
- MD
- Vanderbilt University School of Medicine, Medicine (2013)
- BS
- Michigan State University, Microbiology (2009)
- BA
- Michigan State University, English (2006)
Research
Overview
Public Health Interests
Global Health
ORCID
0000-0002-1432-0596
Research at a Glance
Yale Co-Authors
Frequent collaborators of Joshua Bilsborrow's published research.
Hong-Jai Park
Insoo Kang, MD
Ruth R Montgomery, PhD
Albert C Shaw, MD, PhD
Min Shin, PhD
Subhasis Mohanty, PhD
Publications
2019
Chronic Chikungunya Arthritis and Rheumatoid Arthritis: What They Have in Common
Amaral JK, Bilsborrow JB, Schoen RT. Chronic Chikungunya Arthritis and Rheumatoid Arthritis: What They Have in Common. The American Journal Of Medicine 2019, 133: e91-e97. PMID: 31705850, PMCID: PMC7385732, DOI: 10.1016/j.amjmed.2019.10.005.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsChronic chikungunya arthritisChikungunya arthritisRheumatoid arthritisChikungunya virusAcute febrile illnessAcute illnessFebrile illnessHigh feverInflammatory arthritisMaculopapular rashAcute infectionInfectious causesClinical manifestationsInflammatory processChikungunya feverArthritisFamily TogaviridaeGenus AlphavirusPatientsFeverBetter diagnosisIllnessSignificant proportionRNA virusesVirusMacrophage migration inhibitory factor (MIF) as a therapeutic target for rheumatoid arthritis and systemic lupus erythematosus
Bilsborrow JB, Doherty E, Tilstam PV, Bucala R. Macrophage migration inhibitory factor (MIF) as a therapeutic target for rheumatoid arthritis and systemic lupus erythematosus. Expert Opinion On Therapeutic Targets 2019, 23: 733-744. PMID: 31414920, PMCID: PMC6800059, DOI: 10.1080/14728222.2019.1656718.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsMacrophage migration inhibitory factorSystemic lupus erythematosusRheumatoid arthritisMigration inhibitory factorLupus erythematosusMIF inhibitorsMIF inhibitionAutoimmune diseasesRole of MIFInhibitory factorPathogenesis of RARefractory autoimmune diseasesHigh expressionPleiotropic inflammatory cytokineClinical trial dataPrecision medicine approachGlucocorticoid dependenceInflammatory cytokinesAdaptive immunityTherapeutic targetClinical developmentSmall molecule inhibitorsTrial dataTherapeutic potentialErythematosusTranscriptomic analysis of human IL‐7 receptor alpha low and high effector memory CD8+ T cells reveals an age‐associated signature linked to influenza vaccine response in older adults
Park H, Shin MS, Kim M, Bilsborrow JB, Mohanty S, Montgomery RR, Shaw AC, You S, Kang I. Transcriptomic analysis of human IL‐7 receptor alpha low and high effector memory CD8+ T cells reveals an age‐associated signature linked to influenza vaccine response in older adults. Aging Cell 2019, 18: e12960. PMID: 31044512, PMCID: PMC6612637, DOI: 10.1111/acel.12960.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPeripheral blood cellsPeripheral blood mononuclear cellsEffector memory CD8Influenza vaccine responsesEM CD8T cellsIL-7RαMemory CD8Vaccine responsesBlood cellsOlder adultsIL-7 receptor alphaSignature genesBlood mononuclear cellsHuman peripheral whole bloodAge-associated expansionPeripheral whole bloodGene expression profilesAge-associated changesMeta-analysis studyGlobal transcriptomic profilesMononuclear cellsCD8Receptor alphaExpression profilesTranscriptomic analysis of human IL-7 receptor alphalow and higheffector memory CD8+ T cells reveals an age-associated signature linked to influenza vaccine response in older adults
Park H, Shin M, Kim M, Bilsborrow J, Mohanty S, Montgomery R, Shaw A, Yoo S, Kang I. Transcriptomic analysis of human IL-7 receptor alphalow and higheffector memory CD8+ T cells reveals an age-associated signature linked to influenza vaccine response in older adults. The Journal Of Immunology 2019, 202: 181.22-181.22. DOI: 10.4049/jimmunol.202.supp.181.22.Peer-Reviewed Original ResearchConceptsPeripheral blood cellsPeripheral blood mononuclear cellsInfluenza vaccine responsesT cellsEM CD8Memory CD8Vaccine responsesOlder adultsBlood cellsSignature genesEffector memory CD8Blood mononuclear cellsHuman peripheral whole bloodAge-associated expansionPeripheral whole bloodGene expression profilesAge-associated changesMeta-analysis studyGlobal transcriptomic profilesMononuclear cellsCD8Expression profilesSignificant associationTranscription factorsWhole bloodBrief report: the disability of chronic chikungunya arthritis
Amaral JK, Bilsborrow JB, Schoen RT. Brief report: the disability of chronic chikungunya arthritis. Clinical Rheumatology 2019, 38: 2011-2014. PMID: 30963336, PMCID: PMC7400963, DOI: 10.1007/s10067-019-04529-x.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsChikungunya feverHealth Assessment Questionnaire Disability IndexPain visual analog scaleChronic chikungunya arthritisHAQ-DI scoresVisual analog scaleSpectrum of painChikungunya arthritisDisability IndexRheumatology clinicRheumatic diseasesAnalog scaleArthritic painDisability levelCCA patientsModerate disabilityPatientsPainEntire groupArthritisMean scoreDisabilityScoresUrgent needMorbidity
2018
An Acute Exacerbation of Chronic Obstructive Pulmonary Disease Presenting with Neurological Abnormalities
Do A, Bilsborrow J, and Lin S. An Acute Exacerbation of Chronic Obstructive Pulmonary Disease Presenting with Neurological Abnormalities. Conn Med. 2018; (82)7: 427-29.Peer-Reviewed Original Research
2009
Enhanced Conversion of Racemic α-Arylalanines to (R)-β-Arylalanines by Coupled Racemase/Aminomutase Catalysis
Cox B, Bilsborrow J, Walker K. Enhanced Conversion of Racemic α-Arylalanines to (R)-β-Arylalanines by Coupled Racemase/Aminomutase Catalysis. The Journal Of Organic Chemistry 2009, 74: 6953-6959. PMID: 19711925, DOI: 10.1021/jo9009563.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPhenylalanine aminomutaseRacemic starting materialsOverall reaction yieldBiocatalytic racemizationRacemic substratesReaction mixtureProduction of enantiopureAminomutase reactionBuilding blocksAlanine racemaseCatalysisPseudomonas putidaReactionReaction fluxesEnhanced conversionAminomutaseEnantiopureRacemizationSubstrateDegrees CKT2440
Academic Achievements & Community Involvement
activity Advancing Rheumatology Education and Practice in Rwanda (AREP-R)
ResearchDetails01/01/2022 - PresentKigali, Kigali City, RwandaAbstract/SynopsisThis program will seek to establish a short-term continuing medical education program for rheumatology and musculoskeletal medicine at the University of Rwanda College of Medicine and Health Sciences and its main teaching hospital, Centre Hospitalier Universitaire de Kigali (C.H.U.K.). The goals will be to improve rheumatology knowledge among generals and to stimulate interest in further training opportunities among Rwandan physicians and healthcare trainees.
News
News
- June 25, 2024
Yale Rheumatology Program in Global and Community Health Promotes Collaboration and Addresses Disparities
- May 02, 2023
Yale Team Creates Rheumatology Curriculum in Rwanda
- March 08, 2023
Faculty Network Spotlight: NGN
- February 16, 2022
Discoveries & Impact (February 2022)
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