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INFORMATION FOR

    Anthony Enzo Seddio, MD

    Hospital Resident
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    Hospital Resident

    Biography

    Dr. Anthony Enzo Seddio is an orthopaedic surgery resident at Yale New Haven Hospital. Originally from Southern California, he earned his bachelor's degree in Exercise Science with an emphasis in biomechanics, graduating summa cum laude. Prior to medical school, he owned a personal training company and gym in Los Angeles, integrating his academic background with a hands-on dedication to enhancing his clients' quality of life.

    While earning his MD from Loyola University Chicago, he built upon his longstanding interest in orthopaedics, leading research on novel strategies to improve surgical outcomes. Dr. Seddio was the first to publish on the encouraging reduction in postoperative complications associated with the GLP-1 agonist semaglutide (Ozempic®) for patients undergoing posterior lumbar fusion, rotator cuff repair, and total shoulder arthroplasty.

    His current academic interests center on innovation in spine surgery, with a focus on advancing minimally invasive treatment options for complex spinal pathology and standardizing care pathways to improve patient outcomes following traumatic spine injuries. He has authored more than 60 peer-reviewed original research articles, with publications in the field's most prominent journals including The Spine Journal, Spinal Cord, and Spine, alongside over 100 presentations at national and international conferences.

    At Yale New Haven Hospital, Dr. Seddio leads a prospective, multidisciplinary research initiative focused on optimizing the management of patients with cervical spine trauma. In collaboration with colleagues from Emergency Medicine, Trauma Surgery, Neurosurgery, and Neurology, the team led the development and implementation of the first Cervical Spine Management Care Signature Pathway, which now defines the standard of care across the Yale New Haven Health System.

    Last Updated on October 06, 2026.

    Departments & Organizations

    Education & Training

    Resident
    Yale-New Haven Hospital
    MD
    Loyola University Chicago (2025)

    Research

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Anthony Enzo Seddio's published research.

    Publications

    Featured Publications

    Academic Achievements & Community Involvement

    Activities

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      The Spine Journal | ISSN: 1529-9430

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      North American Spine Society Journal | ISSN: 2666-5484

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      Journal of the American Academy of Orthopaedic Surgeons | ISSN: 1940-5480

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      European Spine Journal | ISSN: 0940-6719

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      Spine Deformity | ISSN: 2212-1358

    Honors

    • honor

      Cerebral Palsy Center Best Paper, "Women With Cerebral Palsy Receive Significantly Less Gynecologic Preventative Care"

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