Jacob Musser
Assistant Professor in Molecular, Cellular and Developmental BiologyCards
About
Research
Publications
2026
Reference-free discovery with barcoded single-cell sequencing
Dehghannasiri R, Kokot M, Starr A, Maziarz J, Gordon T, Tan S, Wang P, Voskoboynik A, Musser J, Deorowicz S, Salzman J. Reference-free discovery with barcoded single-cell sequencing. Nature Biotechnology 2026, 1-6. PMID: 42020848, DOI: 10.1038/s41587-026-03084-6.Peer-Reviewed Original Research
2025
The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution
Sebé-Pedrós A, Tanay A, Lawniczak M, Arendt D, Aerts S, Archibald J, Arnone M, Blaxter M, Cleves P, Coelho S, Dias M, Dunn C, Elek A, Frazer J, Gabaldón T, Gillis J, Grau-Bové X, Guigó R, Hobert O, Huerta-Cepas J, Irimia M, Klein A, Lewin H, Lowe C, Marlow H, Musser J, Nagy L, Najle S, Pachter L, Paez S, Papatheodorou I, Passalacqua M, Rajewsky N, Rhee S, Richards T, Sauka-Spengler T, Saunders L, Seuntjens E, Solana J, Song Y, Technau U, Wang B. The Biodiversity Cell Atlas: mapping the tree of life at cellular resolution. Nature 2025, 645: 877-885. PMID: 40993253, DOI: 10.1038/s41586-025-09312-4.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsComparative Analysis of Convergent Jellyfish Eyes Reveals Extensive Differences in Expression of Vision‐Related Genes
Picciani N, Berger C, Nielsen S, Musser J, Oel A, Stoilova M, Arendt D, Garm A, Oakley T. Comparative Analysis of Convergent Jellyfish Eyes Reveals Extensive Differences in Expression of Vision‐Related Genes. Ecology And Evolution 2025, 15: e71784. PMID: 40661905, PMCID: PMC12259307, DOI: 10.1002/ece3.71784.Peer-Reviewed Original Research
2024
Tripartite origin of the chordate brain
Musser J. Tripartite origin of the chordate brain. Nature Ecology & Evolution 2024, 8: 1782-1783. PMID: 39164590, DOI: 10.1038/s41559-024-02528-z.Peer-Reviewed Original ResearchAuthor Correction: Cross-phyla protein annotation by structural prediction and alignment
Ruperti F, Papadopoulos N, Musser J, Mirdita M, Steinegger M, Arendt D. Author Correction: Cross-phyla protein annotation by structural prediction and alignment. Genome Biology 2024, 25: 50. PMID: 38374049, PMCID: PMC10875831, DOI: 10.1186/s13059-024-03196-9.Commentaries, Editorials and LettersMolecular profiling of sponge deflation reveals an ancient relaxant-inflammatory response
Ruperti F, Becher I, Stokkermans A, Wang L, Marschlich N, Potel C, Maus E, Stein F, Drotleff B, Schippers K, Nickel M, Prevedel R, Musser J, Savitski M, Arendt D. Molecular profiling of sponge deflation reveals an ancient relaxant-inflammatory response. Current Biology 2024, 34: 361-375.e9. PMID: 38181793, DOI: 10.1016/j.cub.2023.12.021.Peer-Reviewed Original Research
2023
Single-cell atlases of two lophotrochozoan larvae highlight their complex evolutionary histories
Piovani L, Leite D, Yañez Guerra L, Simpson F, Musser J, Salvador-Martínez I, Marlétaz F, Jékely G, Telford M. Single-cell atlases of two lophotrochozoan larvae highlight their complex evolutionary histories. Science Advances 2023, 9: eadg6034. PMID: 37531419, PMCID: PMC10396302, DOI: 10.1126/sciadv.adg6034.Peer-Reviewed Original ResearchCross-phyla protein annotation by structural prediction and alignment
Ruperti F, Papadopoulos N, Musser J, Mirdita M, Steinegger M, Arendt D. Cross-phyla protein annotation by structural prediction and alignment. Genome Biology 2023, 24: 113. PMID: 37173746, PMCID: PMC10176882, DOI: 10.1186/s13059-023-02942-9.Peer-Reviewed Original Research
2022
Crustacean leg regeneration restores complex microanatomy and cell diversity
Almazán A, Çevrim Ç, Musser J, Averof M, Paris M. Crustacean leg regeneration restores complex microanatomy and cell diversity. Science Advances 2022, 8: eabn9823. PMID: 36001670, PMCID: PMC9401613, DOI: 10.1126/sciadv.abn9823.Peer-Reviewed Original Research
2021
Single cell RNA sequencing of the Strongylocentrotus purpuratus larva reveals the blueprint of major cell types and nervous system of a non-chordate deuterostome
Paganos P, Voronov D, Musser J, Arendt D, Arnone M. Single cell RNA sequencing of the Strongylocentrotus purpuratus larva reveals the blueprint of major cell types and nervous system of a non-chordate deuterostome. ELife 2021, 10: e70416. PMID: 34821556, PMCID: PMC8683087, DOI: 10.7554/elife.70416.Peer-Reviewed Original Research