GENE 655 Stem Cells: Biology and Application

Course Description

The YSCC has established the first graduate level course in stem cell biology at Yale University. The course entitled, "GENE655: Stem Cells: Biology and Application" is designed for first-year and second-year graduate students to learn the fundamentals of stem cell biology and to gain familiarity with current research in the field. The first class is a general introduction provided by Dr. Haifan Lin, Director of the YSCC. For all other classes, there is first a 45-minute didactic lecture on the subject, followed by a 45-minute "case study" of an original paper presented by an assigned student with class discussion. Topics include: stem cell concepts, methodologies for stem cell research, embryonic stem cells, adult stem cells, cloning and stem cell reprogramming and clinical applications of stem cell research. Details of the Instructors and the lectures they presented in the fall of 2012, the first year the course was held, are listed below.


Undergraduate level cell biology, molecular biology, and genetics.

Class Schedule

Lecture Instructor
General introduction to stem cells H. Lin
Embryonic stem cells N. Ivanova
Germline stem cells H. Lin
Stem cell epigenetics A. Xiao
Somatic cell reprogramming I. Park
Hematopoietic stem cells D. Krause
Mesenchymal stem cells M. Rodeheffer
Cardiac stem cells Y. Qyang
Epidermal stem cells/Niche V. Greco
Neural stem cells Vaccarino
Stem cells and cancer J. Lu
Tissue engineering using stem cells L. Niklason
Clinical use of stem cells D. Krause


For additional information, please contact the Course Director: Dr. In-Hyun Park
Dr. Haifan Lin
Dr. Haifan Lin, Yale Stem Cell Center Director, gives a lecture in the course.