Recent Publications

2023

Trained immunity induced by high-salt diet impedes stroke recovery.Lin TY, Jiang D, Chen WR, Lin JS, Zhang XY, Chen CH, Hsu CL, Lai LC, Chen PH, Yang KC, Sansing LH, Chang CF. EMBO Rep. 2023 Dec 6; 2023 Nov 15. PMID: 37965920.
Heterogeneous murine peribiliary glands orchestrate compartmentalized epithelial renewal.Singh S, Lian Q, Budiman T, Taketo MM, Simons BD, Gupta V. Dev Cell. 2023 Dec 4; 2023 Oct 30. PMID: 37909044.
The H2Bub1-deposition complex is required for human and mouse cardiogenesis.Barish S, Berg K, Drozd J, Berglund-Brown I, Khizir L, Wasson LK, Seidman CE, Seidman JG, Chen S, Brueckner M. Development. 2023 Dec 1; 2023 Dec 1. PMID: 38038666.
Onconephrology: Core Curriculum 2023.Yarandi N, Shirali AC. Am J Kidney Dis. 2023 Dec; 2023 Oct 17. PMID: 37855786.
Bleeding in Critically Ill Children With Malignancy or Hematopoietic Cell Transplant: A Single-Center Prospective Cohort Study.Levasseur J, Fikse L, Mauguen A, Killinger JS, Karam O, Nellis ME. Pediatr Crit Care Med. 2023 Dec 1; 2023 Sep 7. PMID: 37678406.
Therapeutic efficacy of intravenous infusion of mesenchymal stem cells in rat perinatal brain injury.Terada K, Sasaki M, Nagahama H, Kataoka-Sasaki Y, Oka S, Ukai R, Yokoyama T, Iizuka Y, Sakai T, Fukumura S, Tsugawa T, Kocsis JD, Honmou O. Pediatr Res. 2023 Dec; 2023 Jul 8. PMID: 37422495.
Identification of constrained sequence elements across 239 primate genomes.Kuderna LFK, Ulirsch JC, Rashid S, Ameen M, Sundaram L, Hickey G, Cox AJ, Gao H, Kumar A, Aguet F, Christmas MJ, Clawson H, Haeussler M, Janiak MC, Kuhlwilm M, Orkin JD, Bataillon T, Manu S, Valenzuela A, Bergman J, Rouselle M, Silva FE, Agueda L, Blanc J, Gut M, de Vries D, Goodhead I, Harris RA, Raveendran M, Jensen A, Chuma IS, Horvath JE, Hvilsom C, Juan D, Frandsen P, Schraiber JG, de Melo FR, Bertuol F, Byrne H, Sampaio I, Farias I, Valsecchi J, Messias M, da Silva MNF, Trivedi M, Rossi R, Hrbek T, Andriaholinirina N, Rabarivola CJ, Zaramody A, Jolly CJ, Phillips-Conroy J, Wilkerson G, Abee C, Simmons JH, Fernandez-Duque E, Kanthaswamy S, Shiferaw F, Wu D, Zhou L, Shao Y, Zhang G, Keyyu JD, Knauf S, Le MD, Lizano E, Merker S, Navarro A, Nadler T, Khor CC, Lee J, Tan P, Lim WK, Kitchener AC, Zinner D, Gut I, Melin AD, Guschanski K, Schierup MH, Beck RMD, Karakikes I, Wang KC, Umapathy G, Roos C, Boubli JP, Siepel A, Kundaje A, Paten B, Lindblad-Toh K, Rogers J, Marques Bonet T, Farh KK. Nature. 2023 Nov 29; 2023 Nov 29. PMID: 38030727.
Allogeneic hematopoietic cell transplantation for blastic plasmacytoid dendritic cell neoplasm: a CIBMTR analysis.Murthy HS, Zhang MJ, Chen K, Ahmed S, Deotare U, Ganguly S, Kansagra A, Michelis FV, Nishihori T, Patnaik M, Abid MB, Aljurf M, Arai Y, Bacher U, Badar T, Badawy SM, Ballen K, Battiwalla M, Beitinjaneh A, Bejanyan N, Bhatt VR, Brown VI, Martino R, Cahn JY, Castillo P, Cerny J, Chhabra S, Copelan E, Daly A, Dholaria B, Diaz Perez MA, Freytes CO, Grunwald MR, Hashmi S, Hildebrandt GC, Jamy O, Joseph J, Kanakry CG, Khera N, Krem MM, Kuwatsuka Y, Lazarus HM, Lekakis LJ, Liu H, Modi D, Munshi PN, Mussetti A, Palmisiano N, Patel SS, Rizzieri DA, Seo S, Shah MV, Sharma A, Sohl M, Solomon SR, Ulrickson M, Ustun C, van der Poel M, Verdonck LF, Wagner JL, Wang T, Wirk B, Zeidan A, Litzow M, Kebriaei P, Hourigan CS, Weisdorf DJ, Saber W, Kharfan-Dabaja MA. Blood Adv. 2023 Nov 28. PMID: 37792849.
Elevated CDKN1A (P21) mediates β-thalassemia erythroid apoptosis, but its loss does not improve β-thalassemic erythropoiesis.Liang R, Lin M, Menon V, Qiu J, Menon A, Breda L, Arif T, Rivella S, Ghaffari S. Blood Adv. 2023 Nov 28. PMID: 37672319.
Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53.Lee JD, Menasche BL, Mavrikaki M, Uyemura MM, Hong SM, Kozlova N, Wei J, Alfajaro MM, Filler RB, Müller A, Saxena T, Posey RR, Cheung P, Muranen T, Heng YJ, Paulo JA, Wilen CB, Slack FJ. Cell Rep. 2023 Nov 21; 2023 Nov 21. PMID: 37991919.
Mitochondrial leak metabolism induces the Spemann-Mangold Organizer via Hif-1α in Xenopus.MacColl Garfinkel A, Mnatsakanyan N, Patel JH, Wills AE, Shteyman A, Smith PJS, Alavian KN, Jonas EA, Khokha MK. Dev Cell. 2023 Nov 20; 2023 Sep 5. PMID: 37673063.
Longitudinal single-cell transcriptional dynamics throughout neurodegeneration in SCA1.Tejwani L, Ravindra NG, Lee C, Cheng Y, Nguyen B, Luttik K, Ni L, Zhang S, Morrison LM, Gionco J, Xiang Y, Yoon J, Ro H, Haidery F, Grijalva RM, Bae E, Kim K, Martuscello RT, Orr HT, Zoghbi HY, McLoughlin HS, Ranum LPW, Shakkottai VG, Faust PL, Wang S, van Dijk D, Lim J. Neuron. 2023 Nov 16; 2023 Nov 16. PMID: 38016472.
High-grade B-cell lymphoma, not otherwise specified: a multi-institutional retrospective study.Zayac AS, Landsburg DJ, Hughes ME, Bock AM, Nowakowski GS, Ayers EC, Girton M, Hu M, Beckman AK, Li S, Medeiros LJ, Chang JE, Stepanovic A, Kurt H, Sandoval-Sus J, Ansari-Lari MA, Kothari SK, Kress A, Xu ML, Torka P, Sundaram S, Smith SD, Naresh KN, Karimi YH, Epperla N, Bond DA, Farooq U, Saad M, Evens AM, Pandya K, Naik SG, Kamdar M, Haverkos B, Karmali R, Oh TS, Vose JM, Nutsch H, Rubinstein PG, Chaudhry A, Olszewski AJ. Blood Adv. 2023 Nov 14. PMID: 37171397.
Phenotypic and proteomic characterization of the human erythroid progenitor continuum reveal dynamic changes in cell cycle and in metabolic pathways.Papoin J, Yan H, Leduc M, Le Gall M, Narla A, Palis J, Steiner LA, Gallagher PG, Hillyer CD, Gautier EF, Mohandas N, Blanc L. Am J Hematol. 2023 Nov 6; 2023 Nov 6. PMID: 37929634.
Immunological and clinicopathological features predict HER2-positive breast cancer prognosis in the neoadjuvant NeoALTTO and CALGB 40601 randomized trials.Rediti M, Fernandez-Martinez A, Venet D, Rothé F, Hoadley KA, Parker JS, Singh B, Campbell JD, Ballman KV, Hillman DW, Winer EP, El-Abed S, Piccart M, Di Cosimo S, Symmans WF, Krop IE, Salgado R, Loi S, Pusztai L, Perou CM, Carey LA, Sotiriou C. Nat Commun. 2023 Nov 3; 2023 Nov 3. PMID: 37923752.
Distinct clinical phenotypes in paediatric cancer patients with sepsis are associated with different outcomes-an international multicentre retrospective study.Wösten-van Asperen RM, la Roi-Teeuw HM, van Amstel RB, Bos LD, Tissing WJ, Jordan I, Dohna-Schwake C, Bottari G, Pappachan J, Crazzolara R, Comoretto RI, Mizia-Malarz A, Moscatelli A, Sánchez-Martín M, Willems J, Rogerson CM, Bennett TD, Luo Y, Atreya MR, Faustino EVS, Geva A, Weiss SL, Schlapbach LJ, Sanchez-Pinto LN. EClinicalMedicine. 2023 Nov; 2023 Oct 5. PMID: 37842550.
Remission of severe myasthenia gravis after autologous stem cell transplantation.Schlatter MI, Yandamuri SS, O'Connor KC, Nowak RJ, Pham MC, Obaid AH, Redman C, Provost M, McSweeney PA, Pearlman ML, Tees MT, Bowen JD, Nash RA, Georges GE. Ann Clin Transl Neurol. 2023 Nov; 2023 Sep 19. PMID: 37726935.
Classification, risk stratification and response assessment in myelodysplastic syndromes/neoplasms (MDS): A state-of-the-art report on behalf of the International Consortium for MDS (icMDS).Stahl M, Bewersdorf JP, Xie Z, Porta MGD, Komrokji R, Xu ML, Abdel-Wahab O, Taylor J, Steensma DP, Starczynowski DT, Sekeres MA, Sanz G, Sallman DA, Roboz GJ, Platzbecker U, Patnaik MM, Padron E, Odenike O, Nimer SD, Nazha A, Majeti R, Loghavi S, Little RF, List AF, Kim TK, Hourigan CS, Hasserjian RP, Halene S, Griffiths EA, Gore SD, Greenberg P, Figueroa ME, Fenaux P, Efficace F, DeZern AE, Daver NG, Churpek JE, Carraway HE, Buckstein R, Brunner AM, Boultwood J, Borate U, Bejar R, Bennett JM, Wei AH, Santini V, Savona MR, Zeidan AM. Blood Rev. 2023 Nov; 2023 Aug 19. PMID: 37704469.
Nutrient regulation of bone marrow adipose tissue: skeletal implications of weight loss.Rosen CJ, Horowitz MC. Nat Rev Endocrinol. 2023 Nov; 2023 Aug 16. PMID: 37587198.
Racial and Socioeconomic Disparities in Long-Term Outcomes in ≥1 Year Allogeneic Hematopoietic Cell Transplantation Survivors: A CIBMTR Analysis.Blue BJ, Brazauskas R, Chen K, Patel J, Zeidan AM, Steinberg A, Ballen K, Kwok J, Rotz SJ, Perez MAD, Kelkar AH, Ganguly S, Wingard JR, Lad D, Sharma A, Badawy SM, Lazarus HM, Hashem H, Szwajcer D, Knight JM, Bhatt NS, Page K, Beattie S, Arai Y, Liu H, Arnold SD, Freytes CO, Abid MB, Beitinjaneh A, Farhadfar N, Wirk B, Winestone LE, Agrawal V, Preussler JM, Seo S, Hashmi S, Lehmann L, Wood WA, Rangarajan HG, Saber W, Majhail NS. Transplant Cell Ther. 2023 Nov; 2023 Jul 22. PMID: 37482244.
Applications of CRISPR technology in cellular immunotherapy.Zhou X, Renauer PA, Zhou L, Fang SY, Chen S. Immunol Rev. 2023 Nov; 2023 Jul 14. PMID: 37449673.
Interrater reproducibility of the Myoton and durometer devices to quantify sclerotic chronic graft-versus-host disease.Ghosh S, Baker L, Chen F, Khera Z, Vain A, Zhang K, Hood A, Smith H, Chen H, Jagasia M, Tkaczyk E. Arch Dermatol Res. 2023 Nov; 2023 May 25. PMID: 37227518.
Innovations in Stem Cell Therapy for Diabetic Wound Healing.Ho J, Yue D, Cheema U, Hsia HC, Dardik A. Adv Wound Care (New Rochelle). 2023 Nov; 2022 Apr 19. PMID: 35176896.
Post-transplantation cyclophosphamide is associated with increased bacterial infections.Ustun C, Chen M, Kim S, Auletta JJ, Batista MV, Battiwalla M, Cerny J, Gowda L, Hill JA, Liu H, Munshi PN, Nathan S, Seftel MD, Wingard JR, Chemaly RF, Dandoy CE, Perales MA, Riches M, Papanicolaou GA. Bone Marrow Transplant. 2023 Oct 31; 2023 Oct 31. PMID: 37903992.
Negative feedback regulation of MAPK signaling is an important driver of chronic lymphocytic leukemia progression.Ecker V, Brandmeier L, Stumpf M, Giansanti P, Moreira AV, Pfeuffer L, Fens MHAM, Lu J, Kuster B, Engleitner T, Heidegger S, Rad R, Ringshausen I, Zenz T, Wendtner CM, Müschen M, Jellusova J, Ruland J, Buchner M. Cell Rep. 2023 Oct 31; 2023 Oct 4. PMID: 37792532.
ALKBH5 modulates hematopoietic stem and progenitor cell energy metabolism through m(6)A modification-mediated RNA stability control.Gao Y, Zimmer JT, Vasic R, Liu C, Gbyli R, Zheng SJ, Patel A, Liu W, Qi Z, Li Y, Nelakanti R, Song Y, Biancon G, Xiao AZ, Slavoff S, Kibbey RG, Flavell RA, Simon MD, Tebaldi T, Li HB, Halene S. Cell Rep. 2023 Oct 31; 2023 Sep 23. PMID: 37742191.
Precise Therapeutic Targeting of Distinct NRXN1(+/-) Mutations.Fernando MB, Fan Y, Zhang Y, Kammourh S, Murphy AN, Ghorbani S, Onatzevitch R, Pero A, Padilla C, Cao L, Williams S, Fang G, Slesinger PA, Brennand KJ. bioRxiv. 2023 Oct 28; 2023 Oct 28. PMID: 37961635.
IDR-induced CAR condensation improves the cytotoxicity of CAR-Ts against low-antigen cancers.Zhang X, Xiao Q, Zeng L, Hashmi F, Su X. bioRxiv. 2023 Oct 28; 2023 Oct 28. PMID: 37873222.
Mediport use as an acceptable standard for CAR T cell infusion.Eylon M, Prabhu S, John S, King MJM, Bhatt D, Curran KJ, Erickson C, Karras NA, Phillips CL, Satwani P, Hermiston M, Southworth E, Baumeister SHC, Talano JA, MacMillan ML, Rossoff J, Bonifant CL, Myers GD, Rouce RH, Toner K, Driscoll TA, Katsanis E, Salzberg DB, Schiff D, De Oliveira SN, Capitini CM, Pacenta HL, Pfeiffer T, Shah NC, Huynh V, Skiles JL, Fraint E, McNerney KO, Quigg TC, Krueger J, Ligon JA, Fabrizio VA, Baggott C, Laetsch TW, Schultz LM. Front Immunol. 2023; 2023 Oct 27. PMID: 37965315.
Resistance to 2-Hydroxy-Flutamide in Prostate Cancer Cells Is Associated with the Downregulation of Phosphatidylcholine Biosynthesis and Epigenetic Modifications.Mora-Rodríguez JM, Sánchez BG, Sebastián-Martín A, Díaz-Yuste A, Sánchez-Chapado M, Palacín AM, Sánchez-Rodríguez C, Bort A, Díaz-Laviada I. Int J Mol Sci. 2023 Oct 26; 2023 Oct 26. PMID: 37958610.
A fully automated FAIMS-DIA mass spectrometry-based proteomic pipeline.Reilly L, Lara E, Ramos D, Li Z, Pantazis CB, Stadler J, Santiana M, Roberts J, Faghri F, Hao Y, Nalls MA, Narayan P, Liu Y, Singleton AB, Cookson MR, Ward ME, Qi YA. Cell Rep Methods. 2023 Oct 23; 2023 Sep 19. PMID: 37729920.
Apoptotic cells may drive cell death in hair follicles during their regression cycle.Keister BD, Mesa KR, Blagoev KB. Oncotarget. 2023 Oct 19; 2023 Oct 19. PMID: 37861373.
Allogeneic stem cell transplant for treatment of mycosis fungoides and Sezary syndrome: a systematic review and meta-analysis.Goyal A, O'Leary D, Foss F. Bone Marrow Transplant. 2023 Oct 18; 2023 Oct 18. PMID: 37853164.
Modeling SHANK3-associated autism spectrum disorder in Beagle dogs via CRISPR/Cas9 gene editing.Tian R, Li Y, Zhao H, Lyu W, Zhao J, Wang X, Lu H, Xu H, Ren W, Tan QQ, Shi Q, Wang GD, Zhang YP, Lai L, Mi J, Jiang YH, Zhang YQ. Mol Psychiatry. 2023 Oct 17; 2023 Oct 17. PMID: 37848710.
Deficiency of the Heterogeneous Nuclear Ribonucleoprotein U locus leads to delayed hindbrain neurogenesis.Mastropasqua F, Oksanen M, Soldini C, Alatar S, Arora A, Ballarino R, Molinari M, Agostini F, Poulet A, Watts M, Rabkina I, Becker M, Li D, Anderlid BM, Isaksson J, Lundin Remnelius K, Moslem M, Jacob Y, Falk A, Crosetto N, Bienko M, Santini E, Borgkvist A, Bölte S, Tammimies K. Biol Open. 2023 Oct 15; 2023 Oct 10. PMID: 37815090.
Repeated intravenous infusion of mesenchymal stem cells enhances recovery of motor function in a rat model with chronic spinal cord injury.Kurihara K, Sasaki M, Nagahama H, Obara H, Fukushi R, Hirota R, Yoshimoto M, Teramoto A, Kocsis JD, Yamashita T, Honmou O. Brain Res. 2023 Oct 15; 2023 Jul 11. PMID: 37442249.
Molecular programs of regional specification and neural stem cell fate progression in macaque telencephalon.Micali N, Ma S, Li M, Kim SK, Mato-Blanco X, Sindhu SK, Arellano JI, Gao T, Shibata M, Gobeske KT, Duque A, Santpere G, Sestan N, Rakic P. Science. 2023 Oct 13; 2023 Oct 13. PMID: 37824652.
Serum Response Factor Reduces Gene Expression Noise and Confers Cell State Stability.Zhang J, Wu Q, Hu X, Wang Y, Lu J, Chakraborty R, Martin KA, Guo S. Stem Cells. 2023 Oct 8. PMID: 37386941.
Dysregulation of alternative splicing in spinocerebellar ataxia type 1.Olmos V, Thompson E, Gogia N, Luttik K, Veeranki V, Ni L, Sim S, Chen K, Krause DS, Lim J. Hum Mol Genet. 2023 Oct 6; 2023 Oct 6. PMID: 37802886.
Chromatin analysis of adult pluripotent stem cells reveals a unique stemness maintenance strategy.Poulet A, Kratkiewicz AJ, Li D, van Wolfswinkel JC. Sci Adv. 2023 Oct 6; 2023 Oct 6. PMID: 37801496.
Apollo-NADP(+) reveals in vivo adaptation of NADPH/NADP(+) metabolism in electrically activated pancreatic β cells.Bui CV, Boswell CW, Ciruna B, Rocheleau JV. Sci Adv. 2023 Oct 6; 2023 Oct 4. PMID: 37792934.
Fishing for "complements" with vascular organoid models of microvascular disease.Gu SX, Yarovinsky TO, Hwa J. Cell Stem Cell. 2023 Oct 5. PMID: 37802032.
8-oxoguanine riboswitches in bacteria detect and respond to oxidative DNA damage.Hamal Dhakal S, Kavita K, Panchapakesan SSS, Roth A, Breaker RR. Proc Natl Acad Sci U S A. 2023 Oct 3; 2023 Sep 25. PMID: 37748066.
Stem cell-specific ecdysone signaling regulates the development and function of a Drosophila sleep homeostat.Wani AR, Chowdhury B, Luong J, Chaya GM, Patel K, Isaacman-Beck J, Shafer O, Kayser MS, Syed MH. bioRxiv. 2023 Oct 2; 2023 Oct 2. PMID: 37873323.
Starch depletion in the xylem and phloem ray parenchyma of grapevine stems under drought.Prats KA, Fanton AC, Brodersen CR, Furze ME. AoB Plants. 2023 Oct; 2023 Aug 30. PMID: 37899975.
Apoptotic stress causes mtDNA release during senescence and drives the SASP.Victorelli S, Salmonowicz H, Chapman J, Martini H, Vizioli MG, Riley JS, Cloix C, Hall-Younger E, Machado Espindola-Netto J, Jurk D, Lagnado AB, Sales Gomez L, Farr JN, Saul D, Reed R, Kelly G, Eppard M, Greaves LC, Dou Z, Pirius N, Szczepanowska K, Porritt RA, Huang H, Huang TY, Mann DA, Masuda CA, Khosla S, Dai H, Kaufmann SH, Zacharioudakis E, Gavathiotis E, LeBrasseur NK, Lei X, Sainz AG, Korolchuk VI, Adams PD, Shadel GS, Tait SWG, Passos JF. Nature. 2023 Oct; 2023 Oct 11. PMID: 37821702.
A cross-species proteomic map reveals neoteny of human synapse development.Wang L, Pang K, Zhou L, Cebrián-Silla A, González-Granero S, Wang S, Bi Q, White ML, Ho B, Li J, Li T, Perez Y, Huang EJ, Winkler EA, Paredes MF, Kovner R, Sestan N, Pollen AA, Liu P, Li J, Piao X, García-Verdugo JM, Alvarez-Buylla A, Liu Z, Kriegstein AR. Nature. 2023 Oct; 2023 Sep 13. PMID: 37704727.
Injectable hydrogel for sustained delivery of progranulin derivative Atsttrin in treating diabetic fracture healing.Moradi L, Witek L, Vivekanand Nayak V, Cabrera Pereira A, Kim E, Good J, Liu CJ. Biomaterials. 2023 Oct; 2023 Aug 25. PMID: 37639975.
Single-Nucleus Transcriptome Profiling of Dorsolateral Prefrontal Cortex: Mechanistic Roles for Neuronal Gene Expression, Including the 17q21.31 Locus, in PTSD Stress Response.Chatzinakos C, Pernia CD, Morrison FG, Iatrou A, McCullough KM, Schuler H, Snijders C, Bajaj T, DiPietro CP, Soliva Estruch M, Gassen NC, Anastasopoulos C, Bharadwaj RA, Bowlby BC, Hartmann J, Maihofer AX, Nievergelt CM, Ressler NM, Wolf EJ, Carlezon WA Jr, Krystal JH, Kleinman JE, Girgenti MJ, Huber BR, Kellis M, Logue MW, Miller MW, Ressler KJ, Daskalakis NP. Am J Psychiatry. 2023 Oct 1; 2023 Jul 26. PMID: 37491937.
Evaluation of Porcine Psoas Major as a Scaffold Material for Engineered Heart Tissues.Shen S, Shao S, Papadaki M, Kirk JA, Campbell SG. Tissue Eng Part C Methods. 2023 Oct; 2023 Aug 10. PMID: 37450340.
Self-patterning of human stem cells into post-implantation lineages.Pedroza M, Gassaloglu SI, Dias N, Zhong L, Hou TJ, Kretzmer H, Smith ZD, Sozen B. Nature. 2023 Oct; 2023 Jun 27. PMID: 37369348.
VCAM-1(+) hUC-MSCs Exert Considerable Neuroprotection Against Cerebral Infarction in Rats by Suppression of NLRP3-Induced Pyroptosis.Zhang X, Sang X, Chen Y, Yu H, Sun Y, Liang X, Zheng X, Wang X, Yang H, Bi J, Zhang L, Wang P. Neurochem Res. 2023 Oct; 2023 Jun 19. PMID: 37336824.
Microfluidic Immuno-Serolomic Assay Reveals Systems Level Association with COVID-19 Pathology and Vaccine Protection.Kim D, Biancon G, Bai Z, VanOudenhove J, Liu Y, Kothari S, Gowda L, Kwan JM, Buitrago-Pocasangre NC, Lele N, Asashima H, Racke MK, Wilson JE, Givens TS, Tomayko MM, Schulz WL, Longbrake EE, Hafler DA, Halene S, Fan R. Small Methods. 2023 Oct; 2023 Jun 13. PMID: 37312418.
The technological landscape and applications of single-cell multi-omics.Baysoy A, Bai Z, Satija R, Fan R. Nat Rev Mol Cell Biol. 2023 Oct; 2023 Jun 6. PMID: 37280296.
Radiation Therapy Use in Refractory and Relapsed Adolescent and Young Adult Hodgkin Lymphoma: A Report from the Children's Oncology Group.Mailhot Vega RB, Harker-Murray PD, Forlenza CJ, Cole P, Kelly KM, Milgrom SA, Parikh RR, Hodgson DC, Castellino SM, Kahn J, Roberts KB, Constine LS, Hoppe BS. Int J Radiat Oncol Biol Phys. 2023 Oct 1; 2023 Apr 26. PMID: 37116589.
High-plex protein and whole transcriptome co-mapping at cellular resolution with spatial CITE-seq.Liu Y, DiStasio M, Su G, Asashima H, Enninful A, Qin X, Deng Y, Nam J, Gao F, Bordignon P, Cassano M, Tomayko M, Xu M, Halene S, Craft JE, Hafler D, Fan R. Nat Biotechnol. 2023 Oct; 2023 Feb 23. PMID: 36823353.
Young EFIS: Three years of progress - Reflecting on achievements and embracing new horizons.Glymenaki M, Hahn AM, Hausmann A, Kempkes RWM, Kilic G, Kulsvehagen L, Mooslechner AA, Mossadegh-Keller N, Nabhan M, Bechara R. Eur J Immunol. 2023 Sep 26; 2023 Sep 26. PMID: 37751329.
Nuclear NPM-ALK Protects Myc from Proteasomal Degradation and Contributes to Its High Expression in Cancer Stem-Like Cells in ALK-Positive Anaplastic Large Cell Lymphoma.Shang C, Lai J, Haque M, Chen W, Wang P, Lai R. Int J Mol Sci. 2023 Sep 20; 2023 Sep 20. PMID: 37762644.
The physical landscape of CAR-T synapse.Xiong Y, Libby KA, Su X. Biophys J. 2023 Sep 15; 2023 Sep 15. PMID: 37715447.
IL-6 trans-signaling in a humanized mouse model of scleroderma.Odell ID, Agrawal K, Sefik E, Odell AV, Caves E, Kirkiles-Smith NC, Horsley V, Hinchcliff M, Pober JS, Kluger Y, Flavell RA. Proc Natl Acad Sci U S A. 2023 Sep 12; 2023 Sep 5. PMID: 37669366.
Placental growth factor exerts a dual function for cardiomyogenesis and vasculogenesis during heart development.Witman N, Zhou C, Häneke T, Xiao Y, Huang X, Rohner E, Sohlmér J, Grote Beverborg N, Chien KR, Sahara M. Nat Commun. 2023 Sep 5; 2023 Sep 5. PMID: 37669989.
Hemizygous CDKN2A deletion confers worse survival outcomes in IDHmut-noncodel gliomas.Kocakavuk E, Johnson KC, Sabedot TS, Reinhardt HC, Noushmehr H, Verhaak RGW. Neuro Oncol. 2023 Sep 5. PMID: 37329568.
Safety of ovarian cryopreservation and transplantation in patients with acute leukemia: a case series.Sönmezer M, Şükür YE, Saçıntı KG, Özkavukçu S, Kankaya D, Atabekoğlu CS, Cengiz Seval G, Oktay KH. Am J Obstet Gynecol. 2023 Sep 2; 2023 Sep 2. PMID: 37666382.
Life's Essential 8: Optimizing Health in Older Adults.Kumar M, Orkaby A, Tighe C, Villareal DT, Billingsley H, Nanna MG, Kwak MJ, Rohant N, Patel S, Goyal P, Hummel S, Al-Malouf C, Kolimas A, Krishnaswami A, Rich MW, Kirkpatrick J, Damluji AA, Kuchel GA, Forman DE, Alexander KP. JACC Adv. 2023 Sep; 2023 Aug 23. PMID: 37664644.
Scalable production of tissue-like vascularized liver organoids from human PSCs.Harrison SP, Siller R, Tanaka Y, Chollet ME, de la Morena-Barrio ME, Xiang Y, Patterson B, Andersen E, Bravo-Pérez C, Kempf H, Åsrud KS, Lunov O, Dejneka A, Mowinckel MC, Stavik B, Sandset PM, Melum E, Baumgarten S, Bonanini F, Kurek D, Mathapati S, Almaas R, Sharma K, Wilson SR, Skottvoll FS, Boger IC, Bogen IL, Nyman TA, Wu JJ, Bezrouk A, Cizkova D, Corral J, Mokry J, Zweigerdt R, Park IH, Sullivan GJ. Exp Mol Med. 2023 Sep; 2023 Sep 1. PMID: 37653039.
Endothelial FIS1 DeSUMOylation Protects Against Hypoxic Pulmonary Hypertension.Zhou X, Jiang Y, Wang Y, Fan L, Zhu Y, Chen Y, Wang Y, Zhu Y, Wang H, Pan Z, Li Z, Zhu X, Ren R, Ge Z, Lai D, Lai EY, Chen T, Wang K, Liang P, Qin L, Liu C, Qiu C, Simons M, Yu L. Circ Res. 2023 Sep; 2023 Aug 17. PMID: 37589160.
CTLA-4 tail fusion enhances CAR-T antitumor immunity.Zhou X, Cao H, Fang SY, Chow RD, Tang K, Majety M, Bai M, Dong MB, Renauer PA, Shang X, Suzuki K, Levchenko A, Chen S. Nat Immunol. 2023 Sep; 2023 Jul 27. PMID: 37500885.
CD4 T cells and toxicity from immune checkpoint blockade.Earland N, Zhang W, Usmani A, Nene A, Bacchiocchi A, Chen DY, Sznol M, Halaban R, Chaudhuri AA, Newman AM. Immunol Rev. 2023 Sep; 2023 Jul 25. PMID: 37491734.
Single-Cell Transcriptomics of Bone Marrow Stromal Cells in Diversity Outbred Mice: A Model for Population-Level scRNA-Seq Studies.Dillard LJ, Rosenow WT, Calabrese GM, Mesner LD, Al-Barghouthi BM, Abood A, Farber EA, Onengut-Gumuscu S, Tommasini SM, Horowitz MA, Rosen CJ, Yao L, Qin L, Farber CR. J Bone Miner Res. 2023 Sep; 2023 Jul 27. PMID: 37436066.
Advances in glioma models using in vivo electroporation to highjack neurodevelopmental processes.Zhang L, Bordey A. Biochim Biophys Acta Rev Cancer. 2023 Sep; 2023 Jul 9. PMID: 37433417.
Molecular functions of Mrhl lncRNA in mouse spermatogenesis.Kayyar B, Kataruka S, Suresh Akhade V, Rao MRS. Reproduction. 2023 Sep 1; 2023 Jul 31. PMID: 37345883.
Massively parallel knock-in engineering of human T cells.Dai X, Park JJ, Du Y, Na Z, Lam SZ, Chow RD, Renauer PA, Gu J, Xin S, Chu Z, Liao C, Clark P, Zhao H, Slavoff S, Chen S. Nat Biotechnol. 2023 Sep; 2023 Jan 26. PMID: 36702900.
Unravelling human hematopoietic progenitor cell diversity through association with intrinsic regulatory factors.Favaro P, Glass DR, Borges L, Baskar R, Reynolds W, Ho D, Bruce T, Tebaykin D, Scanlon VM, Shestopalov I, Bendall SC. bioRxiv. 2023 Aug 30; 2023 Aug 30. PMID: 37693547.
Insights in piRNA targeting rules.van Wolfswinkel JC. Wiley Interdiscip Rev RNA. 2023 Aug 26; 2023 Aug 26. PMID: 37632327.
Prior cycles of anti-CD20 antibodies affect antibody responses after repeated SARS-CoV-2 mRNA vaccination.Asashima H, Kim D, Wang K, Lele N, Buitrago-Pocasangre NC, Lutz R, Cruz I, Raddassi K, Ruff WE, Racke MK, Wilson JE, Givens TS, Grifoni A, Weiskopf D, Sette A, Kleinstein SH, Montgomery RR, Shaw AC, Li F, Fan R, Hafler DA, Tomayko MM, Longbrake EE. JCI Insight. 2023 Aug 22; 2023 Aug 22. PMID: 37606046.
Insights and strategies for improving equity in graduate school admissions.Cadena MA, Amaya C, Duan D, Rico CA, García-Bayona L, Blanco AT, Agreda YS, Villegas Rodríguez GJ, Ceja A, Martinez VG, Goldman OV, Fernandez RW. Cell. 2023 Aug 17. PMID: 37595563.
Variable CD18 expression in a 22-year-old female with leukocyte adhesion deficiency I: Clinical case and literature review.Bondarenko AV, Boyarchuk OR, Sakovich IS, Polyakova EA, Migas AA, Kupchinskaya AN, Opalinska A, Reich A, Volianska L, Hilfanova AM, Lapiy FI, Chernyshova LI, Volokha AP, Zabara DV, Belevtsev MV, Shman TV, Kukharenko LV, Goltsev MV, Dubouskaya TG, Hancharou AY, Ji W, Lakhani S, Lucas CL, Aleinikova OV, Sharapova SO. Clin Case Rep. 2023 Aug; 2023 Aug 16. PMID: 37601427.
Reduction of nemo-like kinase increases lysosome biogenesis and ameliorates TDP-43-related neurodegeneration.Tejwani L, Jung Y, Kokubu H, Sowmithra S, Ni L, Lee C, Sanders B, Lee PJ, Xiang Y, Luttik K, Soriano A, Yoon J, Park J, Ro HH, Ju H, Liao C, Tieze SM, Rigo F, Jafar-Nejad P, Lim J. J Clin Invest. 2023 Aug 15; 2023 Aug 15. PMID: 37384409.
Long-term Outcomes in Primary CNS Lymphoma After R-MVP and High-Dose Chemotherapy With Autologous Hematopoietic Stem Cell Transplant.Therkelsen KE, Schaff LR, Nandakumar S, Omuro AMP, DeAngelis LM, Grommes C. Neurology. 2023 Aug 15; 2023 Jun 21. PMID: 37344228.
Characterization of enhancer activity in early human neurodevelopment using Massively parallel reporter assay (MPRA) and forebrain organoids.Capauto D, Wang Y, Wu F, Norton S, Mariani J, Inoue F, Crawford GE, Ahituv N, Abyzov A, Vaccarino FM. bioRxiv. 2023 Aug 14; 2023 Aug 14. PMID: 37645832.
Mammalian SWI/SNF chromatin remodeling complexes promote tyrosine kinase inhibitor resistance in EGFR-mutant lung cancer.de Miguel FJ, Gentile C, Feng WW, Silva SJ, Sankar A, Exposito F, Cai WL, Melnick MA, Robles-Oteiza C, Hinkley MM, Tsai JA, Hartley AV, Wei J, Wurtz A, Li F, Toki MI, Rimm DL, Homer R, Wilen CB, Xiao AZ, Qi J, Yan Q, Nguyen DX, Jänne PA, Kadoch C, Politi KA. Cancer Cell. 2023 Aug 14; 2023 Aug 3. PMID: 37541244.
Secretory MPP3 reinforce myeloid differentiation trajectory and amplify myeloid cell production.Kang YA, Paik H, Zhang SY, Chen JJ, Olson OC, Mitchell CA, Collins A, Swann JW, Warr MR, Fan R, Passegué E. J Exp Med. 2023 Aug 7; 2023 Apr 26. PMID: 37115584.
Female naïve human pluripotent stem cells carry X chromosomes with Xa-like and Xi-like folding conformations.Patterson B, Yang B, Tanaka Y, Kim KY, Cakir B, Xiang Y, Kim J, Wang S, Park IH. Sci Adv. 2023 Aug 4; 2023 Aug 4. PMID: 37540754.
Design of a mucin-selective protease for targeted degradation of cancer-associated mucins.Pedram K, Shon DJ, Tender GS, Mantuano NR, Northey JJ, Metcalf KJ, Wisnovsky SP, Riley NM, Forcina GC, Malaker SA, Kuo A, George BM, Miller CL, Casey KM, Vilches-Moure JG, Ferracane MJ, Weaver VM, Läubli H, Bertozzi CR. Nat Biotechnol. 2023 Aug 3; 2023 Aug 3. PMID: 37537499.
DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres.Malla AB, Yu H, Farris D, Kadimi S, Lam TT, Cox AL, Smith ZD, Lesch BJ. EMBO Rep. 2023 Aug 3; 2023 Jun 15. PMID: 37317657.
Immunogenetic Metabolomics Reveals Key Enzymes That Modulate CAR T-cell Metabolism and Function.Renauer P, Park JJ, Bai M, Acosta A, Lee WH, Lin GH, Zhang Y, Dai X, Wang G, Errami Y, Wu T, Clark P, Ye L, Yang Q, Chen S. Cancer Immunol Res. 2023 Aug 3. PMID: 37253111.
Haematopoietic stem and progenitor cell heterogeneity is inherited from the embryonic endothelium.Ghersi JJ, Baldissera G, Hintzen J, Luff SA, Cheng S, Xia IF, Sturgeon CM, Nicoli S. Nat Cell Biol. 2023 Aug; 2023 Jul 17. PMID: 37460694.
Shifting early embryology paradigms: Applications of stem cell-based embryo models in bioengineering.Abel A, Sozen B. Curr Opin Genet Dev. 2023 Aug; 2023 Jun 29. PMID: 37392541.
Ambient particulate matter (PM(2.5)) exposure contributes to neurodegeneration through the microbiome-gut-brain axis: Therapeutic role of melatonin.Panda SR, Chaudhari VB, Ahmed S, Kwatra M, Jala A, Ponneganti S, Pawar SD, Borkar RM, Sharma P, Naidu VGM. Environ Toxicol Pharmacol. 2023 Aug; 2023 Jun 13. PMID: 37321333.
Improving care pathways for people living with rare bone diseases (RBDs): outcomes from the first RBD Summit.Chandran M, Alves I, Carpenter T, Davis M, Hsiao EC, Petryk A, Semler JO, Sleiman M. Osteoporos Int. 2023 Aug; 2023 Jun 9. PMID: 37294334.
Assay optimization for the objective quantification of human multilineage colony-forming units.Thompson EN, Carlino MJ, Scanlon VM, Grimes HL, Krause DS. Exp Hematol. 2023 Aug; 2023 Jun 2. PMID: 37271449.
Correction of a deleterious TBX5 mutation in an induced pluripotent stem cell line (DHMi004-A-1) using a completely plasmid-free CRISPR/Cas 9 approach.Lahm H, Dzilic E, Neb I, Doppler SA, Schneider S, Lange R, Krane M, Dreßen M. Stem Cell Res. 2023 Aug; 2023 May 19. PMID: 37253295.
Female Reproductive Health Outcomes after Hematopoietic Cell Transplantation for Sickle Cell Disease: Is Reduced Intensity Better Than Myeloablative Conditioning?Meacham LR, George S, Veludhandi A, Pruett MC, Haight AE, Arnold SD, Elchuri S, Stenger E, Krishnamurti L. Transplant Cell Ther. 2023 Aug; 2023 May 9. PMID: 37169288.
Strategic use of organoids and organs-on-chip as biomimetic tools.Santos AK, Scalzo S, de Souza RTV, Santana PHG, Marques BL, Oliveira LF, Filho DM, Kihara AH, da Costa Santiago H, Parreira RC, Birbrair A, Ulrich H, Resende RR. Semin Cell Dev Biol. 2023 Jul 30; 2022 Sep 30. PMID: 36192310.
Efficacy and safety of luspatercept versus epoetin alfa in erythropoiesis-stimulating agent-naive, transfusion-dependent, lower-risk myelodysplastic syndromes (COMMANDS): interim analysis of a phase 3, open-label, randomised controlled trial.Platzbecker U, Della Porta MG, Santini V, Zeidan AM, Komrokji RS, Shortt J, Valcarcel D, Jonasova A, Dimicoli-Salazar S, Tiong IS, Lin CC, Li J, Zhang J, Giuseppi AC, Kreitz S, Pozharskaya V, Keeperman KL, Rose S, Shetty JK, Hayati S, Vodala S, Prebet T, Degulys A, Paolini S, Cluzeau T, Fenaux P, Garcia-Manero G. Lancet. 2023 Jul 29; 2023 Jun 10. PMID: 37311468.
Donor Mesenchymal Stem Cells Program Bone Marrow, Altering Macrophages, and Suppressing Endometriosis in Mice.Habata S, Mamillapalli R, Ucar A, Taylor HS. Stem Cells Int. 2023; 2023 Jul 28. PMID: 37545483.
IL-7R licenses a population of epigenetically poised memory CD8(+) T cells with superior antitumor efficacy that are critical for melanoma memory.Micevic G, Daniels A, Flem-Karlsen K, Park K, Talty R, McGeary M, Mirza H, Blackburn HN, Sefik E, Cheung JF, Hornick NI, Aizenbud L, Joshi NS, Kluger H, Iwasaki A, Bosenberg MW, Flavell RA. Proc Natl Acad Sci U S A. 2023 Jul 25; 2023 Jul 17. PMID: 37459511.
Modelling Human Post-Implantation Development via Extra-Embryonic Niche Engineering.Hislop J, Alavi A, Song Q, Schoenberger R, Kamyar KF, LeGraw R, Velazquez J, Mokhtari T, Taheri MN, Rytel M, de Sousa Lopes SMC, Watkins S, Stolz D, Kiani S, Sozen B, Bar-Joseph Z, Ebrahimkhani MR. bioRxiv. 2023 Jul 24; 2023 Jul 24. PMID: 37398391.
MicroRNA-223 limits murine hemogenic endothelial cell specification and myelopoiesis.Wu Y, Paila U, Genet G, Hirschi KK. Dev Cell. 2023 Jul 24; 2023 Jun 8. PMID: 37295435.
More than bad luck: Cancer and aging are linked to replication-driven changes to the epigenome.Minteer CJ, Thrush K, Gonzalez J, Niimi P, Rozenblit M, Rozowsky J, Liu J, Frank M, McCabe T, Higgins-Chen AT, Hofstatter E, Pusztai L, Beckman K, Gerstein M, Levine ME. Sci Adv. 2023 Jul 21; 2023 Jul 19. PMID: 37467337.