Recent Publications

Visualizing nuclear pore complex plasticity with pan-expansion microscopy.Morgan KJ, Carley E, Coyne AN, Rothstein JD, Lusk CP, King MC. J Cell Biol. 2025 Sep 1; 2025 Jun 12. PMID: 40504117.
Novel heterozygous SPI1c.538C>T p.(Leu180Phe) variant causes PU.1 haploinsufficiency leading to agammaglobulinemia.Daddali R, Kettunen K, Turunen T, Knox AVC, Laine P, Chowdhury I, Vänttinen M, Mamia N, Stiegler AL, Boggon TJ, Kere J, Romberg N, Seppänen MRJ, Varjosalo M, Martelius T, Grönholm J. Clin Immunol. 2025 Aug; 2025 Apr 26. PMID: 40294836.
Impact of Conditioning Intensity on Clinical Outcomes of Second Allogeneic Hematopoietic Cell Transplantation for Relapse After First Transplantation.Yoshimura K, Nakasone H, Tamaki M, Hosoi H, Kameda K, Uchida N, Doki N, Fukuda T, Yoshihara S, Mori Y, Nakamae H, Tanaka M, Katayama Y, Eto T, Hasegawa Y, Ota S, Takahashi S, Yoshimitsu M, Ishimaru F, Kanda J, Atsuta Y, Yakushijin K. Am J Hematol. 2025 Jul; 2025 May 23. PMID: 40407015.
Cardiac macrophage: Insights from murine models to translational potential for human studies.Liu Y, Wang TT, Lu Y, Riaz M, Qyang Y. J Mol Cell Cardiol. 2025 Jul; 2025 May 10. PMID: 40354877.
Characterization and Clinical Implications of p53 Dysfunction in Patients With Myelodysplastic Syndromes.Zampini M, Riva E, Lanino L, Sauta E, Antunes Dos Reis R, Ejarque RMA, Maggioni G, Termanini A, Merlotti A, Campagna A, Dall'Olio L, Kulasekararaj A, Calvi M, Di Vito C, Bonometti A, Rahal D, Croci G, Boveri E, Gianelli U, Ponzoni M, Caselli R, Albertazzi S, Todisco G, Ubezio M, Crisafulli L, Frigo A, Lugli E, Mosca E, Acha P, Ghisletti S, Nicassio F, Santoro A, Diez-Campelo M, Solé F, Ades L, Platzbecker U, Santini V, Fenaux P, Haferlach T, Sallman D, Garcia-Manero G, Mavilio D, Remondini D, Castellani G, D'Amico S, Zeidan AM, Komrokji R, Kordasti S, Ficara F, Della Porta MG. J Clin Oncol. 2025 Jun 20; 2025 May 2. PMID: 40315418.
Impact of Abatacept Inclusive Graft Versus Host Disease Prophylaxis in Pediatric Stem Cell Transplantation for Hemoglobinopathy.Shah NC, Ngwube A, Suresh T, Sowa A, Abraham A, Anderson E, Andreansky M, Bhatia M, Chaudhury S, Cuvelier GDE, Dalal J, Grimley M, Jacobsohn D, Kamani N, Krajewski J, Krishnamurti L, Saini S, Skiles J, Shenoy S. Transplant Cell Ther. 2025 Jun 19; 2025 Jun 19. PMID: 40543708.
Exosomes in Dermatology: A Comprehensive Review of Current Applications, Clinical Evidence, and Future Directions.Nahm WJ, Nikas C, Goldust M, Horneck N, Cervantes JA, Burshtein J, Tsoukas M. Int J Dermatol. 2025 Jun 18; 2025 Jun 18. PMID: 40533901.
Biocompatibility Assessment of an Injectable Carbon Nanotube-Functionalized Reverse Thermal Gel for Cardiac Tissue Engineering Applications.Peña B, Bosi S, Knight WE, Cavasin M, Ferrari I, Musani SA, Cobb TM, Kumar M, Montelongo E, Abdel-Hafiz M, Zanetti M, Farahzad N, Alegret N, McKinsey TA, Graw SL, Sbaizero O, Chi C, Vagnozzi RJ, Song K, Taylor MRG, Prato M, Park D, Mestroni L. ACS Appl Bio Mater. 2025 Jun 16; 2025 May 9. PMID: 40343469.
Characterization and lineage tracing of a mouse adipose depot reveal properties conserved with human supraclavicular brown adipose tissue.Li L, Feldman BJ. Stem Cell Reports. 2025 Jun 10; 2025 May 22. PMID: 40409261.
An evaluation of denileukin diftitox for the treatment of relapsed or refractory cutaneous T-cell lymphoma.Goyal A, Foss FM. Expert Opin Biol Ther. 2025 Jun 9; 2025 Jun 9. PMID: 40489974.
A multi-step immune-competent genetic mouse model reveals phenotypic plasticity in uveal melanoma.Xu X, Liu X, Dollar JJ, Liu X, Jasani N, Posorske B, Sriramareddy SN, Jarajapu V, Kuznetsoff JN, Sinard J, Bennett RL, Licht JD, Smalley KSM, Harbour JW, Yu X, Karreth FA. bioRxiv. 2025 Jun 7; 2025 Jun 7. PMID: 40502063.
From genes to geometry: Controlling embryo models by programming genomic activation.McNamara HM, Sozen B. Cell Stem Cell. 2025 Jun 5. PMID: 40480203.
Specification of human brain regions with orthogonal gradients of WNT and SHH in organoids reveals patterning variations across cell lines.Scuderi S, Kang TY, Jourdon A, Nelson A, Yang L, Wu F, Anderson GM, Mariani J, Tomasini L, Sarangi V, Abyzov A, Levchenko A, Vaccarino FM. Cell Stem Cell. 2025 Jun 5; 2025 May 1. PMID: 40315847.
Single-cell panleukemia signatures of HSPC-like blasts predict drug response and clinical outcome.Chen C, Xu J, Sussman JH, Vincent T, Tumulty JS, Yoshimura S, Alikarami F, Yu W, Ding YY, Chen CH, Li EY, Yang A, Qin X, Bandyopadhyay S, Peng J, Pölönen P, Newman H, Wood BL, Hu J, Shraim R, Hughes AD, Diorio C, Uppuluri L, Shi G, Ryan T, Fuller T, Loh ML, Raetz EA, Hunger SP, Pounds SB, Mullighan CG, Frank D, Yang JJ, Bernt KM, Teachey DT, Tan K. Blood. 2025 Jun 5. PMID: 40089994.
Genetic Analysis of the X Chromosome Associates Loci with Progression of Parkinson's Disease.Liao Y, Wu H, Wang J, Corvol JC, Maple-Grødem J, Campbell MC, Elbaz A, Brice A, Schwarzschild MA, Taba P, Kõks S, Beach TG, Alves G, Tysnes OB, Perlmutter JS, Maiti B, van Hilten JJ, Barker RA, Williams-Gray CH, Scherzer CR, Liu G. Mov Disord. 2025 Jun 3; 2025 Jun 3. PMID: 40459076.
Efficacy of Total-Body Irradiation-based Intensified Myeloablative Regimens for Acute Leukemia-An International Collaborative Study.Arai Y, Brazauskas R, He N, Al-Homsi AS, Chhabra S, Battiwalla M, Yanada M, Steinberg A, Diaz Perez MA, Hong S, Kanda J, Bashey A, Frangoul HA, Badawy SM, Verdonck LF, Lazarus HM, Yared JA, Hashem H, Sharma A, Aljurf M, Dias AL, Abid MB, Wirk B, Freytes CO, Zeidan AM, Gergis U, Beitinjaneh A, Askar M, Pu JJ, Lehmann LE, Rangarajan HG, Wood WA, Hashmi S, Yano S, Kako S, Ozawa Y, Doki N, Kanda Y, Fukuda T, Katayama Y, Ichinohe T, Tanaka J, Teshima T, Okamoto S, Atsuta Y, Saber W. EJHaem. 2025 Jun; 2025 May 28. PMID: 40438703.
Evidence of secondary Notch signaling within the rat small intestine.Zagoren E, Dias N, Santos AK, Smith ZD, Ameen NA, Sumigray K. Development. 2025 Jun 1; 2025 Jun 3. PMID: 40371707.
Teduglutide for treatment-refractory severe intestinal acute graft-versus-host disease - a multicenter survey.Brehm N, Biavasco F, Clausen J, Jung J, Maas-Bauer K, Wäsch R, Verbeek M, Nuernbergk C, Ihorst G, Seropian S, Finke J, Gowda L, Sidlik Muskatel R, Peffault de Latour R, Socie G, Wehr C, Michonneau D, Zeiser R. Bone Marrow Transplant. 2025 Jun; 2025 Apr 14. PMID: 40229535.
Phenotypic complexities of rare heterozygous neurexin-1 deletions.Fernando MB, Fan Y, Zhang Y, Tokolyi A, Murphy AN, Kammourh S, Deans PJM, Ghorbani S, Onatzevitch R, Pero A, Padilla C, Williams SE, Flaherty EK, Prytkova IA, Cao L, Knowles DA, Fang G, Slesinger PA, Brennand KJ. Nature. 2025 Jun; 2025 Apr 9. PMID: 40205044.
Olfactory bulb interneurons - The developmental timeline and targeting defined by embryonic neurogenesis.Spence NJ, Martin-Lopez E, Han K, Lefèvre M, Lange NW, Brennan B, Greer CA. Mol Cell Neurosci. 2025 Jun; 2025 Mar 22. PMID: 40122272.
Genetic Analysis of Epidermal Inclusion Cysts Reveals NEK9 Variants as a Common Driver of Comedogenesis and Cyst Formation.Ellis KT, Myung P, Cohen J, Choate KA. J Invest Dermatol. 2025 Jun; 2024 Dec 18. PMID: 39706256.
X-chromosome-wide association study for Alzheimer's disease.Le Borgne J, Gomez L, Heikkinen S, Amin N, Ahmad S, Choi SH, Bis J, Grenier-Boley B, Rodriguez OG, Kleineidam L, Young J, Tripathi KP, Wang L, Varma A, Campos-Martin R, van der Lee S, Damotte V, de Rojas I, Palmal S, Lipton R, Reiman E, McKee A, De Jager P, Bush W, Small S, Levey A, Saykin A, Foroud T, Albert M, Hyman B, Petersen R, Younkin S, Sano M, Wisniewski T, Vassar R, Schneider J, Henderson V, Roberson E, DeCarli C, LaFerla F, Brewer J, Swerdlow R, Van Eldik L, Hamilton-Nelson K, Paulson H, Naj A, Lopez O, Chui H, Crane P, Grabowski T, Kukull W, Asthana S, Craft S, Strittmatter S, Cruchaga C, Leverenz J, Goate A, Kamboh MI, George-Hyslop PS, Valladares O, Kuzma A, Cantwell L, Riemenschneider M, Morris J, Slifer S, Dalmasso C, Castillo A, Küçükali F, Peters O, Schneider A, Dichgans M, Rujescu D, Scherbaum N, Deckert J, Riedel-Heller S, Hausner L, Molina-Porcel L, Düzel E, Grimmer T, Wiltfang J, Heilmann-Heimbach S, Moebus S, Tegos T, Scarmeas N, Dols-Icardo O, Moreno F, Pérez-Tur J, Bullido MJ, Pastor P, Sánchez-Valle R, Álvarez V, Boada M, García-González P, Puerta R, Mir P, Real LM, Piñol-Ripoll G, García-Alberca JM, Royo JL, Rodriguez-Rodriguez E, Soininen H, de Mendonça A, Mehrabian S, Traykov L, Hort J, Vyhnalek M, Thomassen JQ, Pijnenburg YAL, Holstege H, van Swieten J, Ramakers I, Verhey F, Scheltens P, Graff C, Papenberg G, Giedraitis V, Boland A, Deleuze JF, Nicolas G, Dufouil C, Pasquier F, Hanon O, Debette S, Grünblatt E, Popp J, Ghidoni R, Galimberti D, Arosio B, Mecocci P, Solfrizzi V, Parnetti L, Squassina A, Tremolizzo L, Borroni B, Nacmias B, Spallazzi M, Seripa D, Rainero I, Daniele A, Bossù P, Masullo C, Rossi G, Jessen F, Fernandez V, Kehoe PG, Frikke-Schmidt R, Tsolaki M, Sánchez-Juan P, Sleegers K, Ingelsson M, Haines J, Farrer L, Mayeux R, Wang LS, Sims R, DeStefano A, Schellenberg GD, Seshadri S, Amouyel P, Williams J, van der Flier W, Ramirez A, Pericak-Vance M, Andreassen OA, Van Duijn C, Hiltunen M, Ruiz A, Dupuis J, Martin E, Lambert JC, Kunkle B, Bellenguez C. Mol Psychiatry. 2025 Jun; 2024 Dec 4. PMID: 39633006.
Systematic identification of minor histocompatibility antigens predicts outcomes of allogeneic hematopoietic cell transplantation.Cieri N, Hookeri N, Stromhaug K, Li L, Keating J, Díaz-Fernández P, Gómez-García de Soria V, Stevens J, Kfuri-Rubens R, Shao Y, Kooshesh KA, Powell K, Ji H, Hernandez GM, Abelin J, Klaeger S, Forman C, Clauser KR, Sarkizova S, Braun DA, Penter L, Kim HT, Lane WJ, Oliveira G, Kean LS, Li S, Livak KJ, Carr SA, Keskin DB, Muñoz-Calleja C, Ho VT, Ritz J, Soiffer RJ, Neuberg D, Stewart C, Getz G, Wu CJ. Nat Biotechnol. 2025 Jun; 2024 Aug 21. PMID: 39169264.
Impact of Y chromosome loss on the risk of Parkinson's disease and progression.Wang J, Chen X, Du W, Lin C, Liao Y, Corvol JC, Maple-Grødem J, Campbell MC, Elbaz A, Lesage S, Brice A, Schwarzschild MA, Taba P, Kõks S, Alves G, Tysnes OB, Perlmutter JS, Maiti B, van Hilten JJ, Barker RA, Williams-Gray CH, Scherzer CR, Liu G. EBioMedicine. 2025 May 29; 2025 May 29. PMID: 40446401.
Interpretable Differential Abundance Signature (iDAS).Yu L, Lin Y, Xu X, Yang P, Yang JYH. Small Methods. 2025 May 27; 2025 May 27. PMID: 40420636.
Characteristics and Clinical Outcomes of Multiple Myeloma in Adolescents and Young Adults.Olafimihan A, Nwachukwu C, Jackson I, Ogedegbe OJ, Ntukidem OL, Fawehinmi P, Shaka H, Mba B, Farooqui MW. Eur J Haematol. 2025 May 22; 2025 May 22. PMID: 40405541.
From Single Stem Cells to an In Vitro Model of the Post-implantation Human Embryo: A Step-by-Step Guide.Gassaloglu SI, Pedroza M, Sozen B. Methods Mol Biol. 2025 May 22; 2025 May 22. PMID: 40397281.
Recent Advances in HPV Detection: From Traditional Methods to Nanotechnology and the Application of Quantum Dots.He Z, Zheng X, Liu R, Zhao K, Mao D, Zhang L, Wan R, Zhang H, Wang X. Int J Nanomedicine. 2025; 2025 May 21. PMID: 40420910.
Dynamic heterogeneity towards drug resistance in AML cells is primarily driven by epigenomic mechanism unveiled by multi-omics analysis.Zhang Y, Lu Y, Mai L, Wen Z, Dai M, Xu S, Lin X, Luo Y, Qiu Y, Chen Y, Dong Z, Chen C, Meng W, Luo X, Lin G, Tam PKH, Pan X. J Adv Res. 2025 May 21; 2025 May 21. PMID: 40409464.
CD44 Marks Dormant Tumor Cells After HER2 Inhibition in Breast Cancer Cells.Vargas C, Aguirre-Ducler A, Cereceda K, Quijada S, Escobar-Gómez N, Castillo RL, Escobar-Aguirre M. Int J Mol Sci. 2025 May 20; 2025 May 20. PMID: 40430044.
An integrative systems-biology approach defines mechanisms of Alzheimer's disease neurodegeneration.Leventhal MJ, Zanella CA, Kang B, Peng J, Gritsch D, Liao Z, Bukhari H, Wang T, Pao PC, Danquah S, Benetatos J, Nehme R, Farhi S, Tsai LH, Dong X, Scherzer CR, Feany MB, Fraenkel E. Nat Commun. 2025 May 20; 2025 May 20. PMID: 40393985.
Epigenome-wide DNA methylation association study of CHIP provides insight into perturbed gene regulation.Kirmani S, Huan T, Van Amburg JC, Joehanes R, Uddin MM, Nguyen NQH, Yu B, Brody JA, Fornage M, Bressler J, Sotoodehnia N, Ong DA, Puddu F, Floyd JS, Ballantyne CM, Psaty BM, Raffield LM, Natarajan P, Conneely KN, Weinstock JS, Carson AP, Lange LA, Ferrier K, Heard-Costa NL, Murabito J, Bick AG, Levy D. Nat Commun. 2025 May 20; 2025 May 20. PMID: 40393957.
ETS emerges to heat up adipose.Rodeheffer MS. Genes Dev. 2025 May 19; 2025 May 19. PMID: 40389324.
METTL13 is essential for the survival of acute myeloid leukemia cells by regulating MYC.Zhao K, Zhang H, Wang S, Zhou Y, Zhang Z, Kang B, Lin H, Zhang Y, Gu J, Pantoja C, Liu L, He Y, Pan G, Shan Y, Long B. Cell Death Discov. 2025 May 17; 2025 May 17. PMID: 40382345.
Modeling bone marrow microenvironment and hematopoietic dysregulation in Gaucher disease through VavCre mediated Gba deletion.Belinsky G, Ruan J, Fattahi N, Mehta S, Boddupalli CS, Mistry PK, Nair S. Hum Mol Genet. 2025 May 17. PMID: 40197748.
Stem cells and female reproduction: endometrial physiology, disease and therapy.Cevik EC, Mamillapalli R, Taylor HS. Stem Cells. 2025 May 15. PMID: 40317260.
Spatial epigenomic niches underlie glioblastoma cell state plasticity.Kint S, Younes ST, Bao S, Long G, Wouters D, Stephenson E, Lou X, Zhong M, Zhang D, Su G, Enninful A, Yang M, Chen HM, Ellestad K, Anderson C, Moliterno J, Kelly J, Chan JA, Sifrim A, Zhou J, Nikolic A, Fan R, Gallo M. bioRxiv. 2025 May 14; 2025 May 14. PMID: 40463280.
Navigating the dynamic landscape of lower-risk MDS: Advances and emerging insights.Mina A, Madanat Y, Abaza Y, Zeidan AM. Blood Rev. 2025 May 14; 2025 May 14. PMID: 40450506.
Defect in hematopoiesis and embryonic lethality at midgestation of Vps13a/Vps13c double knockout mice.Xu P, Mancuso RI, Leonzino M, Zeiss CJ, Krause DS, De Camilli P. bioRxiv. 2025 May 13; 2025 May 13. PMID: 40463036.
Randomized phase 2 study to assess the role of single-agent nivolumab to maintain remission in acute myeloid leukemia.Pyzer AR, Dillon LW, Sharon E, Karrison TG, Zha Y, Fulton N, Gui G, Andrew G, Streicher H, Sweet K, Yaghmour G, Liu JJ, Jonas BA, Schimmer AD, Grant S, Zeidan AM, Hildebrandt GC, Lowrey CH, Mattison RJ, Palmisiano N, Salhotra A, Tzachanis D, Baer MR, Lin TL, Patel P, Chen H, Stadler WM, Odenike O, Larson RA, Gajewski TF, Hourigan CS, Stock W, Liu H. Blood Adv. 2025 May 13. PMID: 39928953.
De novo variants disrupt an LDB1-regulated transcriptional network in congenital ventriculomegaly.Allington G, Mehta NH, Dennis E, Mekbib KY, Reeves B, Kiziltug E, Chen S, Zhao S, Duy PQ, Saleh M, Ang LC, Fan B, Nelson-Williams C, Moreno-de-Luca A, Haider S, Lifton RP, Alper SL, McGee S, Jin SC, Kahle KT. Brain. 2025 May 13. PMID: 39680505.
Clinical Evidence of Mesenchymal Stromal Cells for Cerebral Palsy: Scoping Review with Meta-Analysis of Efficacy in Gross Motor Outcomes.Paton MCB, Griffin AR, Blatch-Williams R, Webb A, Verter F, Couto PS, Bersenev A, Dale RC, Popat H, Novak I, Finch-Edmondson M. Cells. 2025 May 12; 2025 May 12. PMID: 40422203.
High-Deductible Health Plans and Out-of-Pocket Health Care Costs Among Younger Patients With Multiple Myeloma.Fiala MA, Ji M, Slade M, Huber JH, Shih YH, Wang M, Colditz GA, Wang SY, Vij R, Chang SH. JCO Oncol Pract. 2025 May 12; 2025 May 12. PMID: 40354593.
Inhibition of MIF with an Allosteric Inhibitor Triggers Cell Cycle Arrest in Acute Myeloid Leukemia.Pantouris G, Khurana L, Tilstam P, Benner A, Cho TY, Lelaidier M, Perrée M, Rosenbaum Z, Leng L, Foss F, Bhandari V, Verma A, Bucala R, Lolis EJ. ACS Omega. 2025 May 6; 2025 Apr 22. PMID: 40352549.
Molecular basis of cell fate plasticity - insights from the privileged cells.Scalf SM, Wu Q, Guo S. Curr Opin Genet Dev. 2025 May 5; 2025 May 5. PMID: 40327951.
Extracellular Vesicle (EV) Targeted Cells Release Secondary Effector EVs: Indication of How To Account for Histocompatibility and Disease Specificity of EV Treatments.Askenase PW. J Extracell Vesicles. 2025 May. PMID: 40415199.
Therapeutic Efficacy of Mesenchymal Stem Cells in Modulating Oxidative Stress in Puromycin-Induced Nephropathy.Iizuka Y, Sasaki M, Terada K, Sakai T, Nagaoka Y, Fukumura S, Kocsis JD, Tsugawa T, Honmou O. Pathophysiology. 2025 May 1; 2025 May 1. PMID: 40407599.
Nivolumab plus ifosfamide, carboplatin, and etoposide are a highly effective first salvage regimen in high-risk relapsed/refractory Hodgkin lymphoma.Mei M, Palmer J, Lee HJ, Isufi I, Chen R, Tsai NC, Armenian S, Godfrey J, Song JY, Baird JH, Thiruvengadam S, Samara Y, Flores J, Peters L, Rosen S, Kwak L, Forman SJ, Herrera AF. Hemasphere. 2025 May; 2025 Apr 30. PMID: 40313510.
The retrotransposon-derived capsid genes PNMA1 and PNMA4 maintain reproductive capacity.Wood TWP, Henriques WS, Cullen HB, Romero M, Blengini CS, Sarathy S, Sorkin J, Bekele H, Jin C, Kim S, Wang X, Laureau R, Chemiakine A, Khondker RC, Isola JVV, Stout MB, Gennarino VA, Mogessie B, Jain D, Schindler K, Suh Y, Wiedenheft B, Berchowitz LE. Nat Aging. 2025 May; 2025 Apr 22. PMID: 40263616.
Translational genomics of osteoarthritis in 1,962,069 individuals.Hatzikotoulas K, Southam L, Stefansdottir L, Boer CG, McDonald ML, Pett JP, Park YC, Tuerlings M, Mulders R, Barysenka A, Arruda AL, Tragante V, Rocco A, Bittner N, Chen S, Horn S, Srinivasasainagendra V, To K, Katsoula G, Kreitmaier P, Tenghe AMM, Gilly A, Arbeeva L, Chen LG, de Pins AM, Dochtermann D, Henkel C, Höijer J, Ito S, Lind PA, Lukusa-Sawalena B, Minn AKK, Mola-Caminal M, Narita A, Nguyen C, Reimann E, Silberstein MD, Skogholt AH, Tiwari HK, Yau MS, Yue M, Zhao W, Zhou JJ, Alexiadis G, Banasik K, Brunak S, Campbell A, Cheung JTS, Dowsett J, Faquih T, Faul JD, Fei L, Fenstad AM, Funayama T, Gabrielsen ME, Gocho C, Gromov K, Hansen T, Hudjashov G, Ingvarsson T, Johnson JS, Jonsson H, Kakehi S, Karjalainen J, Kasbohm E, Lemmelä S, Lin K, Liu X, Loef M, Mangino M, McCartney D, Millwood IY, Richman J, Roberts MB, Ryan KA, Samartzis D, Shivakumar M, Skou ST, Sugimoto S, Suzuki K, Takuwa H, Teder-Laving M, Thomas L, Tomizuka K, Turman C, Weiss S, Wu TT, Zengini E, Zhang Y, Ferreira MAR, Babis G, Baras A, Barker T, Carey DJ, Cheah KSE, Chen Z, Cheung JP, Daly M, de Mutsert R, Eaton CB, Erikstrup C, Furnes ON, Golightly YM, Gudbjartsson DF, Hailer NP, Hayward C, Hochberg MC, Homuth G, Huckins LM, Hveem K, Ikegawa S, Ishijima M, Isomura M, Jones M, Kang JH, Kardia SLR, Kloppenburg M, Kraft P, Kumahashi N, Kuwata S, Lee MTM, Lee PH, Lerner R, Li L, Lietman SA, Lotta L, Lupton MK, Mägi R, Martin NG, McAlindon TE, Medland SE, Michaëlsson K, Mitchell BD, Mook-Kanamori DO, Morris AP, Nabika T, Nagami F, Nelson AE, Ostrowski SR, Palotie A, Pedersen OB, Rosendaal FR, Sakurai-Yageta M, Schmidt CO, Sham PC, Singh JA, Smelser DT, Smith JA, Song YQ, Sørensen E, Tamiya G, Tamura Y, Terao C, Thorleifsson G, Troelsen A, Tsezou A, Uchio Y, Uitterlinden AG, Ullum H, Valdes AM, van Heel DA, Walters RG, Weir DR, Wilkinson JM, Winsvold BS, Yamamoto M, Zwart JA, Stefansson K, Meulenbelt I, Teichmann SA, van Meurs JBJ, Styrkarsdottir U, Zeggini E. Nature. 2025 May; 2025 Apr 9. PMID: 40205036.
A Blueprint for Translational Precision Medicine in Autism Spectrum Disorder and Related Neurogenetic Syndromes.Thom RP, Warren TL, Khan S, Muhle RA, Wang PP, Brennand K, Zürcher NR, Veenstra-VanderWeele J, Hoffman EJ. J Child Adolesc Psychopharmacol. 2025 May; 2025 Mar 26. PMID: 40138183.
Contemporary understanding of myeloid-derived suppressor cells in the acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) tumor microenvironment.Alhajahjeh A, Stahl M, Kim TK, Kewan T, Stempel JM, Zeidan AM, Bewersdorf JP. Expert Rev Anticancer Ther. 2025 May; 2025 Mar 27. PMID: 40122075.
Engaging Parents of Children With Sickle Cell Disease in Shared Decision-Making for Hydroxyurea: The ENGAGE-HU Study.Hildenbrand AK, Mara CA, Murphy B, Hood AM, Johnson Y, Shook LM, Real FJ, Nwankwo C, Hackworth R, Badawy SM, Thompson AA, Raphael JL, Smith-Whitley K, King AA, Calhoun C, Creary SE, Reader SK, Bhasin N, Sobota AE, Houston P, Gipson C, DeBaun MR, Saving KL, Treadwell M, Quinn CT, Crosby LE. Pediatr Blood Cancer. 2025 May; 2025 Mar 6. PMID: 40051208.
Clinical-genomic profiling of MDS to inform allo-HCT: recommendations from an international panel on behalf of the EBMT.Gurnari C, Robin M, Adès L, Aljurf M, Almeida A, Duarte FB, Bernard E, Cutler C, Della Porta MG, De Witte T, DeZern A, Drozd-Sokolowska J, Duncavage E, Fenaux P, Gagelmann N, Garcia-Manero G, Haferlach C, Haferlach T, Hasserjian R, Hellström-Lindberg E, Jacoby M, Kulasekararaj A, Lindsley RC, Maciejewski JP, Makishima H, Malcovati L, Mittelman M, Myhre AE, Ogawa S, Onida F, Papaemmanuil E, Passweg J, Platzbecker U, Pleyer L, Raj K, Santini V, Sureda A, Tobiasson M, Voso MT, Yakoub-Agha I, Zeidan A, Walter M, Kröger N, McLornan DP, Cazzola M. Blood. 2025 May 1. PMID: 39970324.
US Geriatric Assessment Practices for Older Adults Undergoing Hematopoietic Cell Transplantation or Chimeric Antigen Receptor T Cell Therapy: An American Society for Transplantation and Cellular Therapy Physician Survey from the Aging Special Interest Group and Committee on Practice Guidelines.Munshi PN, Olin RL, Wall S, McCurdy SR, Al-Juhaishi T, Baker J, Bhatt VR, Chokr N, Dahi P, DeFilipp Z, Espinoza-Gutarra M, Farhan S, Gowda L, Hamilton BK, Inamoto Y, Jayani R, Kharfan-Dabaja MA, Lin R, Meyers G, Mishra A, Murthy HS, Nawas M, Rosko AE, Ruiz M, Sorror ML, Sung AD, Carpenter PA, Hamadani M, Artz AS. Transplant Cell Ther. 2025 May; 2025 Feb 15. PMID: 39961473.
CDK16(+) Luminal Progenitor Cell-Like Tumor Cells Interacted with POSTN(+) Cancer-Associated Fibroblasts Associate with Chemo-Resistance In Breast Cancer.Ding X, Wu Q, Du Y, Ji MM, Yang H, Hu Q, Ye Y. Small Methods. 2025 May; 2025 Feb 10. PMID: 39930931.
Reply.Zhao JJ, Sundar R. Gastroenterology. 2025 May; 2025 Jan 15. PMID: 39824393.
In vivo AAV-SB-CRISPR screens of tumor-infiltrating primary NK cells identify genetic checkpoints of CAR-NK therapy.Peng L, Renauer PA, Sferruzza G, Yang L, Zou Y, Fang Z, Park JJ, Chow RD, Zhang Y, Lin Q, Bai M, Sanchez A, Zhang Y, Lam SZ, Ye L, Chen S. Nat Biotechnol. 2025 May; 2024 Jun 25. PMID: 38918616.
How Delayed Cord Clamping Saves Newborn Lives.Mercer J, Saether E, King T, Maul H, Kennedy HP, Erickson-Owens D, Andersson O, Rabe H. Children (Basel). 2025 Apr 30; 2025 Apr 30. PMID: 40426764.
Circular RNAs increase during vascular cell differentiation and are biomarkers for vascular disease.Northoff BH, Herbst A, Wenk C, Weindl L, Gäbel G, Brezski A, Zarnack K, Küpper A, Dimmeler S, Moretti A, Laugwitz KL, Engelhardt S, Maegdefessel L, Boon RA, Doppler S, Dreßen M, Lahm H, Lange R, Krane M, Krohn K, Kohlmaier A, Holdt LM, Teupser D. Cardiovasc Res. 2025 Apr 29. PMID: 39901821.
The impact of orthopoxvirus vaccination and Mpox infection on cross-protective immunity: a multicohort observational study.Crandell J, Monteiro VS, Pischel L, Fang Z, Conde L, Zhong Y, Lawres L, de Asis GM, Maciel G, Zaleski A, Lira GS, Higa LM, Breban MI, Vogels CBF, Caria J, Pinto AR, Almeida V, Maltez F, Cordeiro R, Póvoas D, Grubaugh ND, Aoun-Barakat L, Grifoni A, Sette A, Castineiras TM, Chen S, Yildirim I, Vale AM, Omer SB, Lucas C. Lancet Microbe. 2025 Apr 28; 2025 Apr 28. PMID: 40311645.
Impact of memory T cells on SARS-CoV-2 vaccine response in hematopoietic stem cell transplant.VanOudenhove J, Liu Y, Nelakanti R, Kim D, Busarello E, Ovalle NT, Qi Z, Mamillapalli P, Siddon A, Bai Z, Axtmayer A, Corso C, Kothari S, Foss F, Isufi I, Tebaldi T, Gowda L, Fan R, Seropian S, Halene S. PLoS One. 2025; 2025 Apr 28. PMID: 40294012.
Renal bleeding: imaging and interventions in patients with tumors.Singer ED, Karbasian N, Katz DS, Wong VK, Abdelsalam ME, Stanietzky N, Nguyen TT, Shenoy-Bhangle AS, Badawy M, Revzin MV, Shehata MA, Eltaher M, Elsayes KM, Korivi BR. Diagn Interv Radiol. 2025 Apr 28; 2024 Jun 14. PMID: 38874163.
Cardiomyocyte-specific NHE1 overexpression confers protection against myocardial infarction during hyperglycemia.Jiang K, Su F, Deng R, Xu Y, Qin A, Yuan X, Xing D, Chen Y, Wang D, Shen L, Hwa J, Hou L, Xiang Y. Cardiovasc Diabetol. 2025 Apr 26; 2025 Apr 26. PMID: 40287728.
Correction of sodium channel mutations in sensory neurons reverses aberrant properties.Shim J, Tanaka B, Taub DG, Mis MA, Schulman BR, Snavely A, Cheng YC, Laedermann C, Buttermore ED, Ren A, Hermawan C, Dou D, Kawaguchi R, Geschwind DH, Dib-Hajj S, Waxman SG, Woolf CJ. Brain. 2025 Apr 25; 2025 Apr 25. PMID: 40279376.
Massive Bleeding in Children With Cancer or Hematopoietic Cell Transplant: International, Multicenter Retrospective Study, 2017-2021.Nellis ME, Steiner ME, Bhar S, McArthur J, McMichael A, Rahrig AL, Leeper C, Perdichizzi S, Chiusolo F, Shamash J, Bruns N, Schreiber H, Sharron MP, Butragueño-Laiseca L, Killinger JS, Pringle CP, Koenig SM, Josephson C, Crawford D, Scott BL, Remy KE, Puthawala C, Spinella PC. Pediatr Crit Care Med. 2025 Apr 25; 2025 Apr 25. PMID: 40277427.
Mechanisms of Ellagic Acid (EA)-Mediated Osteogenic Differentiation of Human Dental Pulp-Derived Stem Cells.Naidu P, Das M, Hansda S, Prateeksha P, Howlader MSI, Siraj MA, Das H. ACS Omega. 2025 Apr 22; 2025 Apr 13. PMID: 40290905.
Temporal and spatial omics technologies for 4D profiling.Reynolds DE, Roh YH, Oh D, Vallapureddy P, Fan R, Ko J. Nat Methods. 2025 Apr 22; 2025 Apr 22. PMID: 40263585.
Dietary oleic acid drives obesogenic adipogenesis via modulation of LXRα signaling.Wing A, Jeffery E, Church CD, Goodell J, Saavedra-Peña RDM, Saha M, Holtrup B, Voisin M, Alavi NS, Floody M, Wang Z, Zapadka TE, Garabedian MJ, Varshney R, Rudolph MC, Rodeheffer MS. Cell Rep. 2025 Apr 22; 2025 Apr 11. PMID: 40208790.
Lithium fine tunes lipid membranes through phospholipid binding.Bunel L, Adrien V, Coleman J, Heo P, Pincet F. Sci Rep. 2025 Apr 17; 2025 Apr 17. PMID: 40246965.
Intravenous infusion of mesenchymal stem cells increased axonal signal intensity in the rubrospinal tract in spinal cord injury.Hirota R, Sasaki M, Teramoto A, Yamashita T, Kocsis JD, Honmou O. Mol Brain. 2025 Apr 16; 2025 Apr 16. PMID: 40241097.
Crossing the Valley of Death in Spinal Cord Injury: Learning from Successful Translators.Failli V, Strittmatter SM, Schwab ME, Anderson AJ, Ruban A, Al-Ali H, Curt A, Cohen A, Hsieh JTC. Neurotrauma Rep. 2025; 2025 Apr 14. PMID: 40309162.
H3.1K27M-induced misregulation of the TONSOKU-H3.1 pathway causes genomic instability.Yuan W, Huang YC, LeBlanc C, Poulet A, De Luna Vitorino FN, Valsakumar D, Dean R, Garcia BA, van Wolfswinkel JC, Voigt P, Jacob Y. Nat Commun. 2025 Apr 14; 2025 Apr 14. PMID: 40229276.
TSC-mTORC1 Pathway in Postnatal V-SVZ Neurodevelopment.Feliciano DM, Bordey A. Biomolecules. 2025 Apr 12; 2025 Apr 12. PMID: 40305300.
Natural killer cells' functional impairment drives the immune escape of pre-malignant clones in early-stage myelodysplastic syndromes.Rodriguez-Sevilla JJ, Ganan-Gomez I, Kumar B, Thongon N, Ma F, Chien KS, Kim YJ, Yang H, Loghavi S, Tan R, Adema V, Li Z, Tanaka T, Uryu H, Kanagal-Shamanna R, Al-Atrash G, Bejar R, Banerjee PP, Lynn Cha S, Montalban-Bravo G, Dougherty M, Fernandez Laurita MC, Wheeler N, Jia B, Papapetrou EP, Izzo F, Dueñas DE, McAllen S, Gu Y, Todisco G, Ficara F, Della Porta MG, Jain A, Takahashi K, Clise-Dwyer K, Halene S, Bertilaccio MTS, Garcia-Manero G, Daher M, Colla S. Nat Commun. 2025 Apr 11; 2025 Apr 11. PMID: 40216768.
Non-syndromic craniosynostosis.Alperovich M, Tonello C, Mayes LC, Kahle KT. Nat Rev Dis Primers. 2025 Apr 10; 2025 Apr 10. PMID: 40210850.
Functional Validation of Alcohol Dependence-Associated FYN Variants Using Gene Editing and Stem Cell Study Approaches.Cakir B, Tanaka Y, Choe MS, Chu PY, Xiang Y, Kim KY, Zhong M, Gelernter J, Zhang H, Krystal J, Park IH. Int J Stem Cells. 2025 Apr 10; 2025 Apr 10. PMID: 40205763.
Symposia Report of The Annual Biological Sciences Section Meeting of the Gerontological Society of America 2023, Tampa, Florida.Rogina B, Anderson R, LeBrasseur NK, Curran SP, Yousefzadeh MJ, Ghosh B, Duque G, Howlett S, Austad S, Demuth I, Gerstorf D, Korfhage J, Lombard DB, Abadir P, Christensen K, Carey JR, Alberts SC, Campos F, Palavicini JP, Palmer A, Bell J, Basisty N, de Cabo R, Gomes A, Dixit VD, Sen P, Baur JA, Imai SI, Li X, Valdez G, Orr ME, Pletcher S, Andersen J, Jones L, Castillo-Azofeida D, Bonaguidi M, Suh Y, Duncan FE, Murray A, Wang MC, Burkewitz K, Henne M, Zhou K, Bouhrara M, Benjamini D, Kolind S, Walker KA, Reiter DA, Dean DC 3rd, Gorbunova V, Gladyshev VN, Palovics R, Niedernhofer LJ, Fan R, Bueckle AD, Hurley J, Esser KA, Kapahi P, Sato S, Jiang N, Ashiqueali SA, Diaz J, Mishra SP, Raimundo N, Banarjee R, Allsopp R, Reynolds LM, Zhang B, Sebastiani P, Monti S, Schork N, Rappaport N. J Gerontol A Biol Sci Med Sci. 2025 Apr 7. PMID: 39932386.
ASTCT and USCLC clinical practice recommendations for allogeneic stem cell transplant in mycosis fungoides and Sézary syndrome.Goyal A, O'Leary D, Dabaja B, Weng WK, Zain J, Cutler C, Guitart J, Kim YH, Geskin LJ, Hoppe RT, Wilson LD, Beaven AW, Horwitz S, Allen PB, Barta SK, Bohjanen K, Brammer JE, Carter JB, Comfere N, DeSimone JA, Dusenbery K, Duvic M, Huen A, Jagadeesh D, Kelsey CR, Khodadoust MS, Lechowicz MJ, Mehta-Shah N, Moskowitz AJ, Olsen EA, Poh C, Pro B, Querfeld C, Sauter C, Sokol L, Sokumbi O, Wilcox RA, Zic JA, Gru A, Hamadani M, Foss F. J Am Acad Dermatol. 2025 Apr 6; 2025 Apr 6. PMID: 40199382.
HIF regulates multiple translated endogenous retroviruses: Implications for cancer immunotherapy.Jiang Q, Braun DA, Clauser KR, Ramesh V, Shirole NH, Duke-Cohan JE, Nabilsi N, Kramer NJ, Forman C, Lippincott IE, Klaeger S, Phulphagar KM, Chea V, Kim N, Vanasse AP, Saad E, Parsons T, Carr-Reynolds M, Carulli I, Pinjusic K, Jiang Y, Li R, Syamala S, Rachimi S, Verzani EK, Stevens JD, Lane WJ, Camp SY, Meli K, Pappalardi MB, Herbert ZT, Qiu X, Cejas P, Long HW, Shukla SA, Van Allen EM, Choueiri TK, Churchman LS, Abelin JG, Gurer C, MacBeath G, Childs RW, Carr SA, Keskin DB, Wu CJ, Kaelin WG Jr. Cell. 2025 Apr 3; 2025 Feb 28. PMID: 40023154.
Nonselective β-Adrenergic Receptor Inhibitors Impair Hematopoietic Regeneration in Mice and Humans after Hematopoietic Cell Transplants.Nishino J, Hu W, Kishtagari A, Shen B, Gao X, Blackman CM, Kassim A, Marneni N, Cherukuri AV, Vittrup R, Kalkan FN, Shah R, Ahn C, Gao A, Ahmedrabie A, Collins RH, Zeidan AM, Bidikian A, Gowda L, Shaffer BC, Madanat YF, Zhao Z, Chung SS, Morrison SJ. Cancer Discov. 2025 Apr 2. PMID: 39786370.
Integrating Pulmonary and Systemic Transcriptomic Profiles to Characterize Lung Injury after Pediatric Hematopoietic Stem Cell Transplant.Pearce EM, Evans E, Mayday MY, Reyes G, Simon MR, Blum J, Kim H, Mu J, Shaw PJ, Rowan CM, Auletta JJ, Martin PL, Hurley C, Kreml EM, Qayed M, Abdel-Azim H, Keating AK, Cuvelier GDE, Hume JR, Killinger JS, Godder K, Hanna R, Duncan CN, Quigg TC, Castillo P, Lalefar NR, Fitzgerald JC, Mahadeo KM, Satwani P, Moore TB, Hanisch B, Abdel-Mageed A, Davis DB, Hudspeth MP, Yanik GA, Pulsipher MA, Dvorak CCJL, Zinter MS. medRxiv. 2025 Apr 1; 2025 Apr 1. PMID: 40236411.
The interplay between Salmonella and host: Mechanisms and strategies for bacterial survival.Zhao H, Zhang X, Zhang N, Zhu L, Lian H. Cell Insight. 2025 Apr; 2025 Feb 13. PMID: 40177681.
Pluripotent cell states and fates in human embryo models.Sozen B, Tam PPL, Pera MF. Development. 2025 Apr 1; 2025 Apr 2. PMID: 40171916.
Invigorating discovery and clinical translation of aging biomarkers.Jacques E, Herzog C, Ying K, Tomusiak A, Kasamoto J, Sehgal R, Paulson S, Reinhard J, Träuble J, Hastings WJ, Tyshkovskiy A, Hägg S, Earls JC, Behrens CE, Lasky-Su J, Zhou G, Morgen E, Tsang JS, Marioni RE, Ma XJ, Stolzing A, Glorioso C, Gootenberg JS, Abudayyeh OO, Argentieri MA, Mak RH, Cox LS, Brack AS, Lauc G, Furman D, Buenrostro JD, Schumacher B, Justice JN, Woods T, Gobel D, Perez VI, Sinclair DA, Maier AB, Barzilai N, Snyder MP, Wyss-Coray T, Horvath S, Ferrucci L, Poganik JR, Moqri M, Gladyshev VN. Nat Aging. 2025 Apr. PMID: 40164770.
MFGE-8, a Corona Protein on Extracellular Vesicles, Mediates Self-Renewal and Survival of Human Pluripotent Stem Cells.Lee Y, Kim H, Yoon H, Cho S, Kim J, Lee J, Choi SH, Cho H, Woo DH, Park JH, Han C, Kim JH. J Extracell Vesicles. 2025 Apr. PMID: 40130745.
Quantitative characterization of cell niches in spatially resolved omics data.Birk S, Bonafonte-Pardàs I, Feriz AM, Boxall A, Agirre E, Memi F, Maguza A, Yadav A, Armingol E, Fan R, Castelo-Branco G, Theis FJ, Bayraktar OA, Talavera-López C, Lotfollahi M. Nat Genet. 2025 Apr; 2025 Mar 18. PMID: 40102688.
Initial management of patients with acquired aplastic anemia in the United States: results from a large national claims database.Stempel JM, Wang R, Lee AI, Zeidan AM, Ma X, Podoltsev NA. Ann Hematol. 2025 Apr; 2025 Mar 19. PMID: 40102305.
Microstructural patterns in substantia nigra subregions are associated with depression and olfactory impairments in Parkinson's disease.Mozafar M, Manshadi ZD, Molaei Z, Babaei H, Mansouri M, Shahbazi S, Shakeri S, Mirhosseini H, Gulisashvili D, Mayeli M. Clin Neurol Neurosurg. 2025 Apr; 2025 Mar 8. PMID: 40080943.
Engineering Mice to Study Human Immunity.Sefik E, Xiao T, Chiorazzi M, Odell I, Zhang F, Agrawal K, Micevic G, Flavell RA. Annu Rev Immunol. 2025 Apr; 2025 Feb 28. PMID: 40020225.
Modeling forebrain regional development and connectivity by human brain organoids.Choe MS, Lo C, Park IH. Curr Opin Genet Dev. 2025 Apr; 2025 Feb 20. PMID: 39983347.
Chimerism testing in myeloid malignancies: techniques, considerations, and connections to post-transplant outcomes.Puzo CJ, Siddon AJ. Pathology. 2025 Apr; 2025 Jan 17. PMID: 39934013.
Alemtuzumab and thrombotic thrombocytopenic purpura: Analysis of an international surveillance database and systematic literature review.Jacobs JW, Binns TC, Schlafer D, Woo JS, Booth GS, Adkins BD. Transfus Apher Sci. 2025 Apr; 2025 Jan 27. PMID: 39883995.
The maternal-to-zygotic transition: reprogramming of the cytoplasm and nucleus.Kojima ML, Hoppe C, Giraldez AJ. Nat Rev Genet. 2025 Apr; 2024 Nov 25. PMID: 39587307.
Durable mixed chimerism may permit subsequent immunosuppression-free intestinal transplantation-A proof-of-principle study.Patwardhan S, Gunes ME, Manell E, Hong J, Jordache P, Chauhan I, Almesallmy A, Mulder H, Ekanayake-Alper D, Hajosi D, Ko HM, Shanmugarajah K, Cetrulo CL, Nowak G, Sachs DH, Sykes M, Weiner J. Am J Transplant. 2025 Apr; 2024 Oct 22. PMID: 39442670.
Rethinking AMPK: A Reversible Switch Fortifying Cancer Cell Stress-Resilience.Mohanty SS, Warrier S, Rangarajan A. Yale J Biol Med. 2025 Mar; 2025 Mar 31. PMID: 40165808.
An in vivo screen identifies NAT10 as a master regulator of brain metastasis.Chen JF, Xu P, Cai WL, Chen H, Wingrove E, Shi X, Li W, Biancon G, Zhang M, Balabaki A, Krop ED, Asare E, Zhang Y, Yin M, Tebaldi T, Meier JL, Westbrook TF, Halene S, Liu Y, Shen H, Nguyen DX, Yan Q. Sci Adv. 2025 Mar 28; 2025 Mar 26. PMID: 40138393.
Generation of Orthogonal Gradients of the Matrix Stiffness and Chemotactic Cues in a Suspended Array of Hydrogel to Study hMSCs Migration.Xu Z, Ponek A, Thomas J, Qyang Y. ACS Sens. 2025 Mar 28; 2025 Feb 28. PMID: 40021359.
Resiliency in Child-Caregiver Dyads and the Impact on Health Outcomes in Sickle Cell Disease.Zavadil JA, Azul M, Carpenter BD, Calhoun C. Children (Basel). 2025 Mar 21; 2025 Mar 21. PMID: 40310076.
Spatially resolved genome-wide joint profiling of epigenome and transcriptome with spatial-ATAC-RNA-seq and spatial-CUT&Tag-RNA-seq.Li H, Bao S, Farzad N, Qin X, Fung AA, Zhang D, Bai Z, Tao B, Fan R. Nat Protoc. 2025 Mar 21; 2025 Mar 21. PMID: 40119005.