Recent Publications

2023

Generation of two CRISPR/Cas edited human induced pluripotent stem cell lines (DHMi005-A-3 and DHMi005-A-4) carrying a FLAG-tag after exon 9 of the TBX5 gene.Lahm H, Stieglbauer S, Neb I, Doppler SA, Schneider S, Dzilic E, Lange R, Krane M, Dreßen M. Stem Cell Res. 2023 Feb; 2022 Dec 28. PMID: 36610218.
An update on the diagnosis and treatment of adrenoleukodystrophy.Gujral J, Sethuram S. Curr Opin Endocrinol Diabetes Obes. 2023 Feb 1; 2022 Nov 14. PMID: 36373727.
Machine learning identifies T cell receptor repertoire signatures associated with COVID-19 severity.Park JJ, Lee KAV, Lam SZ, Moon KS, Fang Z, Chen S. Commun Biol. 2023 Jan 20; 2023 Jan 20. PMID: 36670287.
BTG1 mutation yields supercompetitive B cells primed for malignant transformation.Mlynarczyk C, Teater M, Pae J, Chin CR, Wang L, Arulraj T, Barisic D, Papin A, Hoehn KB, Kots E, Ersching J, Bandyopadhyay A, Barin E, Poh HX, Evans CM, Chadburn A, Chen Z, Shen H, Isles HM, Pelzer B, Tsialta I, Doane AS, Geng H, Rehman MH, Melnick J, Morgan W, Nguyen DTT, Elemento O, Kharas MG, Jaffrey SR, Scott DW, Khelashvili G, Meyer-Hermann M, Victora GD, Melnick A. Science. 2023 Jan 20; 2023 Jan 20. PMID: 36656933.
DNA methylation of the promoter region at the CREB1 binding site is a mechanism for the epigenetic regulation of brain specific PKMζ.Pramio DT, Vieceli FM, Varella-Branco E, Goes CP, Kobayashi GS, da Silva Pelegrina DV, de Moraes BC, El Allam A, De Kumar B, Jara G, Farfel JM, Bennett DA, Kundu S, Viapiano MS, Reis EMR, de Oliveira PSL, Dos Santos E Passos-Bueno MR, Rothlin CV, Ghosh S, Schechtman D. Biochim Biophys Acta Gene Regul Mech. 2023 Jan 19; 2023 Jan 19. PMID: 36682583.
RAMIHM generates fully human monoclonal antibodies by rapid mRNA immunization of humanized mice and BCR-seq.Ren P, Peng L, Yang L, Suzuki K, Fang Z, Renauer PA, Lin Q, Bai M, Li T, Clark P, Klein D, Chen S. Cell Chem Biol. 2023 Jan 19; 2023 Jan 13. PMID: 36640761.
STRA6 is essential for induction of vascular smooth muscle lineages in human embryonic cardiac outflow tract development.Zhou C, Häneke T, Rohner E, Sohlmér J, Kameneva P, Artemov A, Adameyko I, Sahara M. Cardiovasc Res. 2023 Jan 13; 2023 Jan 13. PMID: 36635482.
Dome1-JAK-STAT signaling between parasite and host integrates vector immunity and development.Rana VS, Kitsou C, Dutta S, Ronzetti MH, Zhang M, Bernard Q, Smith AA, Tomás-Cortázar J, Yang X, Wu MJ, Kepple O, Li W, Dwyer JE, Matias J, Baljinnyam B, Oliver JD, Rajeevan N, Pedra JHF, Narasimhan S, Wang Y, Munderloh U, Fikrig E, Simeonov A, Anguita J, Pal U. Science. 2023 Jan 13; 2023 Jan 13. PMID: 36634189.
Advances in myelodysplastic syndromes: promising novel agents and combination strategies.Madanat YF, Xie Z, Zeidan AM. Expert Rev Hematol. 2023 Jan 12; 2023 Jan 12. PMID: 36620919.
Tissue resident iNKT17 cells facilitate cancer cell extravasation in liver metastasis via interleukin-22.Giannou AD, Kempski J, Shiri AM, Lücke J, Zhang T, Zhao L, Zazara DE, Cortesi F, Riecken K, Amezcua Vesely MC, Low JS, Xu H, Kaffe E, Garcia-Perez L, Agalioti T, Yamada Y, Jungraithmayr W, Zigmond E, Karstens KF, Steglich B, Wagner J, Konczalla L, Carambia A, Schulze K, von Felden J, May P, Briukhovetska D, Bedke T, Brockmann L, Starzonek S, Lange T, Koch C, Riethdorf S, Pelczar P, Böttcher M, Sabihi M, Huber FJ, Reeh M, Grass JK, Wahib R, Seese H, Stüben BO, Fard-Aghaie M, Duprée A, Scognamiglio P, Plitzko G, Meiners J, Soukou S, Wittek A, Manthey C, Maroulis IC, Arck PC, Perez D, Gao B, Zarogiannis SG, Strowig T, Pasqualini R, Arap W, Gosálvez JS, Kobold S, Prinz I, Guse AH, Tachezy M, Ghadban T, Heumann A, Li J, Melling N, Mann O, Izbicki JR, Pantel K, Schumacher U, Lohse AW, Flavell RA, Gagliani N, Huber S. Immunity. 2023 Jan 10. PMID: 36630911.
A rapid RIG-I signaling relay mediates efficient antiviral response.Thoresen DT, Galls D, Götte B, Wang W, Pyle AM. Mol Cell. 2023 Jan 5; 2022 Dec 14. PMID: 36521492.
Stem cell-derived sensory neurons modelling inherited erythromelalgia: normalization of excitability.Alsaloum M, Labau JIR, Liu S, Effraim PR, Waxman SG. Brain. 2023 Jan 5. PMID: 35088838.
Mutations in the transcriptional regulator MeCP2 severely impact key cellular and molecular signatures of human astrocytes during maturation.Sun J, Osenberg S, Irwin A, Ma LH, Lee N, Xiang Y, Li F, Wan YW, Park IH, Maletic-Savatic M, Ballas N. Cell Rep. 2023 Jan 4; 2023 Jan 4. PMID: 36640327.
Current advances in primate genomics: novel approaches for understanding evolution and disease.Juan D, Santpere G, Kelley JL, Cornejo OE, Marques-Bonet T. Nat Rev Genet. 2023 Jan 4; 2023 Jan 4. PMID: 36599936.
Stem Cell Therapy for Alzheimer's Disease: A Scoping Review for 2017-2022.Duan Y, Lyu L, Zhan S. Biomedicines. 2023 Jan 3; 2023 Jan 3. PMID: 36672626.
Epigenetically suppressed tumor cell intrinsic STING promotes tumor immune escape.Zheng H, Wu L, Xiao Q, Meng X, Hafiz A, Yan Q, Lu R, Cao J. Biomed Pharmacother. 2023 Jan; 2022 Nov 24. PMID: 36436495.
Humoral and Cellular Response of Transplant Recipients to a Third Dose of mRNA SARS-CoV-2 Vaccine: A Systematic Review and Meta-analysis.Bailey AJM, Maganti HB, Cheng W, Shorr R, Arianne Buchan C, Allan DS. Transplantation. 2023 Jan 1; 2022 Nov 4. PMID: 36398334.
Signaling network model of cardiomyocyte morphological changes in familial cardiomyopathy.Khalilimeybodi A, Riaz M, Campbell SG, Omens JH, McCulloch AD, Qyang Y, Saucerman JJ. J Mol Cell Cardiol. 2023 Jan; 2022 Nov 10. PMID: 36370475.
Long-Term Organ Function After HCT for SCD: A Report From the Sickle Cell Transplant Advocacy and Research Alliance.Stenger E, Xiang Y, Wetzel M, Gillespie S, Chellapandian D, Shah R, Arnold SD, Bhatia M, Chaudhury S, Eckrich MJ, Kanter J, Kasow KA, Krajewski J, Nickel RS, Ngwube AI, Olson TS, Rangarajan HG, Wobma H, Guilcher GMT, Horan JT, Krishnamurti L, Shenoy S, Abraham A. Transplant Cell Ther. 2023 Jan; 2022 Oct 20. PMID: 36273784.
The Use of Extracorporeal Membrane Oxygenation as a Bridge to Bone Marrow Transplantation in a Patient With High-risk Acute Myeloid Leukemia.Nader M, Bonde P, Massaro S, Giuliano JS Jr, Shah N. J Pediatr Hematol Oncol. 2023 Jan 1; 2022 Oct 10. PMID: 36219701.

2022

How I Manage Transplant Ineligible Patients with Myelodysplastic Neoplasms.Gurnari C, Xie Z, Zeidan AM. Clin Hematol Int. 2022 Dec 27; 2022 Dec 27. PMID: 36574201.
Deciphering the role of RNA structure in translation efficiency.Lin J, Chen Y, Zhang Y, Lin H, Ouyang Z. BMC Bioinformatics. 2022 Dec 23; 2022 Dec 23. PMID: 36564729.
Disparities in receiving disease-directed therapy, allogeneic stem cell transplantation in non-Hispanic Black patients with TP53-mutated acute myeloid leukemia.Badar T, Litzow MR, Shallis RM, Patel A, Saliba AN, Burkart M, Bewersdorf JP, Stahl M, De Camargo Correia GS, Guru Murthy GS, Abaza Y, Duvall A, Bradshaw D, Kota V, Dinner S, Goldberg AD, Palmisiano N, Al Kali A, Atallah E. Cancer. 2022 Dec 21; 2022 Dec 21. PMID: 36545710.
Pathogenesis of chronic chikungunya arthritis: Resemblances and links with rheumatoid arthritis.Amaral JK, Bingham CO 3rd, Taylor PC, Vilá LM, Weinblatt ME, Schoen RT. Travel Med Infect Dis. 2022 Dec 20; 2022 Dec 20. PMID: 36549417.
Deconvolution of in vivo protein-RNA contacts using fractionated eCLIP-seq.Biancon G, Busarello E, Joshi P, Lesch BJ, Halene S, Tebaldi T. STAR Protoc. 2022 Dec 16; 2022 Nov 16. PMID: 36595959.
Human Umbilical Cord-Based Therapeutics: Stem Cells and Blood Derivatives for Female Reproductive Medicine.Rodríguez-Eguren A, Gómez-Álvarez M, Francés-Herrero E, Romeu M, Ferrero H, Seli E, Cervelló I. Int J Mol Sci. 2022 Dec 14; 2022 Dec 14. PMID: 36555583.
Outcomes in Patients with FLT3-Mutated Relapsed/ Refractory Acute Myelogenous Leukemia Who Underwent Transplantation in the Phase 3 ADMIRAL Trial of Gilteritinib versus Salvage Chemotherapy.Perl AE, Larson RA, Podoltsev NA, Strickland S, Wang ES, Atallah E, Schiller GJ, Martinelli G, Neubauer A, Sierra J, Montesinos P, Recher C, Yoon SS, Maeda Y, Hosono N, Onozawa M, Kato T, Kim HJ, Hasabou N, Nuthethi R, Tiu R, Levis MJ. Transplant Cell Ther. 2022 Dec 13; 2022 Dec 13. PMID: 36526260.
Recruited monocytes/macrophages drive pulmonary neutrophilic inflammation and irreversible lung tissue remodeling in cystic fibrosis.Öz HH, Cheng EC, Di Pietro C, Tebaldi T, Biancon G, Zeiss C, Zhang PX, Huang PH, Esquibies SS, Britto CJ, Schupp JC, Murray TS, Halene S, Krause DS, Egan ME, Bruscia EM. Cell Rep. 2022 Dec 13. PMID: 36516754.
Susan L. Solomon (1951-2022): Advocate, Innovator, Catalyst.Fossati V, Greco V, Arlotta P, Aiyar RS. Stem Cell Reports. 2022 Dec 13. PMID: 36516737.
Regulation of bone homeostasis by MERTK and TYRO3.Engelmann J, Zarrer J, Gensch V, Riecken K, Berenbrok N, Luu TV, Beitzen-Heineke A, Vargas-Delgado ME, Pantel K, Bokemeyer C, Bhamidipati S, Darwish IS, Masuda E, Burstyn-Cohen T, Alberto EJ, Ghosh S, Rothlin C, Hesse E, Taipaleenmäki H, Ben-Batalla I, Loges S. Nat Commun. 2022 Dec 12; 2022 Dec 12. PMID: 36509738.
Mitochondrial dysfunction induces ALK5-SMAD2-mediated hypovascularization and arteriovenous malformations in mouse retinas.Zhang H, Li B, Huang Q, López-Giráldez F, Tanaka Y, Lin Q, Mehta S, Wang G, Graham M, Liu X, Park IH, Eichmann A, Min W, Zhou JH. Nat Commun. 2022 Dec 10; 2022 Dec 10. PMID: 36496409.
Efficacy, Safety, and Challenges of CAR T-Cells in the Treatment of Solid Tumors.Chen Q, Lu L, Ma W. Cancers (Basel). 2022 Dec 3; 2022 Dec 3. PMID: 36497465.
Characterization of human basal ganglia organoids.Brady MV, Mariani J, Koca Y, Szekely A, King RA, Bloch MH, Landeros-Weisenberger A, Leckman JF, Vaccarino FM. Mol Psychiatry. 2022 Dec. PMID: 36536052.
Isotope tracing reveals distinct substrate preference in murine melanoma subtypes with differing anti-tumor immunity.Zhang X, Halberstam AA, Zhu W, Leitner BP, Thakral D, Bosenberg MW, Perry RJ. Cancer Metab. 2022 Dec 1; 2022 Dec 1. PMID: 36457136.
Double knockout CRISPR screen for cancer resistance to T cell cytotoxicity.Park JJ, Codina A, Ye L, Lam S, Guo J, Clark P, Zhou X, Peng L, Chen S. J Hematol Oncol. 2022 Dec 1; 2022 Dec 1. PMID: 36456981.
Structure-function analysis of the role of megakaryoblastic leukemia 1 in megakaryocyte polyploidization.Reed FE, Eskow NM, Min E, Carlino M, Mancuso R, Kwon N, Smith EC, Larsuel ST, Wang L, Scanlon V, Krause DS. Haematologica. 2022 Dec 1; 2022 Dec 1. PMID: 36453520.
Mispatterning and interneuron deficit in Tourette Syndrome basal ganglia organoids.Brady MV, Mariani J, Koca Y, Szekely A, King RA, Bloch MH, Landeros-Weisenberger A, Leckman JF, Vaccarino FM. Mol Psychiatry. 2022 Dec; 2022 Nov 29. PMID: 36447010.
Familial risk of psychosis in obsessive-compulsive disorder: Impact on clinical characteristics, comorbidity and treatment response.Balachander S, Thatikonda NS, Kannampuzha AJ, Bhattacharya M, Sheth S, Ramesh V, Chandy Alexander A, Muthukumaran M, Joseph MS, Selvaraj S, Ithal D, Sreeraj VS, John JP, Venkatasubramanian G, Viswanath B, Reddy YJ, Jain S. J Psychiatr Res. 2022 Dec; 2022 Oct 20. PMID: 36368245.
Gradual differentiation uncoupled from cell cycle exit generates heterogeneity in the epidermal stem cell layer.Cockburn K, Annusver K, Gonzalez DG, Ganesan S, May DP, Mesa KR, Kawaguchi K, Kasper M, Greco V. Nat Cell Biol. 2022 Dec; 2022 Nov 10. PMID: 36357619.
Transcription factor antagonism regulates heterogeneity in embryonic stem cell states.Hu S, Metcalf E, Mahat DB, Chan L, Sohal N, Chakraborty M, Hamilton M, Singh A, Singh A, Lees JA, Sharp PA, Garg S. Mol Cell. 2022 Dec 1; 2022 Nov 9. PMID: 36356583.
Rethinking the cilia hypothesis of hydrocephalus.Duy PQ, Greenberg ABW, Butler WE, Kahle KT. Neurobiol Dis. 2022 Dec; 2022 Oct 29. PMID: 36341771.
Vaccination as a therapeutic strategy for Nasopharyngeal carcinoma.Huang J, Harris E, Lorch J. Oral Oncol. 2022 Dec; 2022 Nov 1. PMID: 36332445.
Finding consistency in classifications of myeloid neoplasms: a perspective on behalf of the International Workshop for Myelodysplastic Syndromes.Zeidan AM, Bewersdorf JP, Buckstein R, Sekeres MA, Steensma DP, Platzbecker U, Loghavi S, Boultwood J, Bejar R, Bennett JM, Borate U, Brunner AM, Carraway H, Churpek JE, Daver NG, Della Porta M, DeZern AE, Efficace F, Fenaux P, Figueroa ME, Greenberg P, Griffiths EA, Halene S, Hasserjian RP, Hourigan CS, Kim N, Kim TK, Komrokji RS, Kutchroo V, List AF, Little RF, Majeti R, Nazha A, Nimer SD, Odenike O, Padron E, Patnaik MM, Roboz GJ, Sallman DA, Sanz G, Stahl M, Starczynowski DT, Taylor J, Xie Z, Xu M, Savona MR, Wei AH, Abdel-Wahab O, Santini V. Leukemia. 2022 Dec; 2022 Oct 20. PMID: 36266326.
Assessing the quality and readability of online content on shock wave therapy for erectile dysfunction.Reddy RV, Golan R, Loloi J, Diaz P, Saltzman RG, Watane A, Ramasamy R. Andrologia. 2022 Dec; 2022 Oct 14. PMID: 36240784.
Update of pathophysiology and treatment options of seborrheic keratosis.Gorai S, Ahmad S, Raza SSM, Khan HD, Raza MA, Etaee F, Cockerell CJ, Apalla Z, Goldust M. Dermatol Ther. 2022 Dec; 2022 Nov 1. PMID: 36226729.
Engineering multicellular living systems-a Keystone Symposia report.Cable J, Arlotta P, Parker KK, Hughes AJ, Goodwin K, Mummery CL, Kamm RD, Engle SJ, Tagle DA, Boj SF, Stanton AE, Morishita Y, Kemp ML, Norfleet DA, May EE, Lu A, Bashir R, Feinberg AW, Hull SM, Gonzalez AL, Blatchley MR, Montserrat Pulido N, Morizane R, McDevitt TC, Mishra D, Mulero-Russe A. Ann N Y Acad Sci. 2022 Dec; 2022 Sep 30. PMID: 36177947.
Proteomic profiling reveals an association between ALDH and oxidative phosphorylation and DNA damage repair pathways in human colon adenocarcinoma stem cells.Wang Y, Chen Y, Garcia-Milian R, Golla JP, Charkoftaki G, Lam TT, Thompson DC, Vasiliou V. Chem Biol Interact. 2022 Dec 1; 2022 Sep 23. PMID: 36162455.
Recent advances for using human induced-pluripotent stem cells as pain-in-a-dish models of neuropathic pain.Labau JIR, Andelic M, Faber CG, Waxman SG, Lauria G, Dib-Hajj SD. Exp Neurol. 2022 Dec; 2022 Sep 12. PMID: 36100046.
Role of quercetin and rutin in enhancing the therapeutic potential of mesenchymal stem cells for cold induced burn wound.Irfan F, Jameel F, Khan I, Aslam R, Faizi S, Salim A. Regen Ther. 2022 Dec; 2022 Aug 23. PMID: 36092499.
Response to Letter to the Editor: IRF8 is a Reliable Monoblast Marker for Acute Monocytic Leukemias but does not Discriminate Between Monoblasts and Plasmacytoid Dendritic Cells.Xu ML, Katz SG. Am J Surg Pathol. 2022 Dec 1; 2022 Aug 29. PMID: 36040049.
Enhanced Network in Corticospinal Tracts after Infused Mesenchymal Stem Cells in Spinal Cord Injury.Hirota R, Sasaki M, Kataoka-Sasaki Y, Oshigiri T, Kurihara K, Fukushi R, Oka S, Ukai R, Yoshimoto M, Kocsis JD, Yamashita T, Honmou O. J Neurotrauma. 2022 Dec; 2022 Jul 14. PMID: 35611987.
The crossroads of cancer epigenetics and immune checkpoint therapy.Micevic G, Bosenberg MW, Yan Q. Clin Cancer Res. 2022 Nov 30; 2022 Nov 30. PMID: 36449280.
Reduced LYNX1 expression in transcriptome of human iPSC-derived neural progenitors modeling fragile X syndrome.Talvio K, Minkeviciene R, Townsley KG, Achuta VS, Huckins LM, Corcoran P, Brennand KJ, Castrén ML. Front Cell Dev Biol. 2022; 2022 Nov 21. PMID: 36506088.
RIPK1 mutations causing infantile-onset IBD with inflammatory and fistulizing features.Sultan M, Adawi M, Kol N, McCourt B, Adawi I, Baram L, Tal N, Werner L, Lev A, Snapper SB, Barel O, Konnikova L, Somech R, Shouval DS. Front Immunol. 2022; 2022 Nov 18. PMID: 36466854.
Integrating Single-Cell Transcriptome and Network Analysis to Characterize the Therapeutic Response of Chronic Myeloid Leukemia.Ma J, Pettit N, Talburt J, Wang S, Weissman SM, Yang MQ. Int J Mol Sci. 2022 Nov 18; 2022 Nov 18. PMID: 36430822.
Simultaneous transfer of one good-quality and one poor-quality cleavage stage embryo does not improve pregnancy outcomes.Liu J, Kumar I, Li T, Ding Y, Tian Q, Tang X, Huang X, Hu W, Liu Y, Wang Z. Hum Fertil (Camb). 2022 Nov 15; 2022 Nov 15. PMID: 36380565.
Lung Tissue Engineering: Toward a More Deliberate Approach.Leiby KL, Niklason LE. ACS Biomater Sci Eng. 2022 Nov 14; 2022 Jan 24. PMID: 35073058.
Leukemia inhibitory factor protects against graft-versus-host disease while preserving graft-versus-leukemia activity.Wang J, Chang CY, Yang X, Zhou F, Liu J, Zhu S, Yu XZ, Liu C, O'Sullivan TE, Xie P, Feng Z, Hu W. Blood. 2022 Nov 10. PMID: 35981499.
Membrane potential drives the exit from pluripotency and cell fate commitment via calcium and mTOR.Sempou E, Kostiuk V, Zhu J, Cecilia Guerra M, Tyan L, Hwang W, Camacho-Aguilar E, Caplan MJ, Zenisek D, Warmflash A, Owens NDL, Khokha MK. Nat Commun. 2022 Nov 5; 2022 Nov 5. PMID: 36335122.
Glis1 and oxaloacetate in nucleus pulposus stromal cell somatic reprogramming and survival.Lufkin L, Samanta A, Baker D, Lufkin S, Schulze J, Ellis B, Rose J, Lufkin T, Kraus P. Front Mol Biosci. 2022; 2022 Nov 3. PMID: 36406265.
Immune niches orchestrated by intestinal mesenchymal stromal cells lining the crypt-villus.Sun H, Tan J, Chen H, Wu N, Su B. Front Immunol. 2022; 2022 Nov 3. PMID: 36405734.
The RIG-I receptor adopts two different conformations for distinguishing host from viral RNA ligands.Wang W, Pyle AM. Mol Cell. 2022 Nov 3; 2022 Oct 21. PMID: 36272408.
Advanced in vitro models: Microglia in action.Cakir B, Kiral FR, Park IH. Neuron. 2022 Nov 2. PMID: 36327894.
Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts.Adema V, Ma F, Kanagal-Shamanna R, Thongon N, Montalban-Bravo G, Yang H, Peslak SA, Wang F, Acha P, Sole F, Lockyer P, Cassari M, Maciejewski JP, Visconte V, Gañán-Gómez I, Song Y, Bueso-Ramos C, Pellegrini M, Tan TM, Bejar R, Carew JS, Halene S, Santini V, Al-Atrash G, Clise-Dwyer K, Garcia-Manero G, Blobel GA, Colla S. Blood Cancer Discov. 2022 Nov 2. PMID: 35926182.
Targeting hippocampal neurogenesis to protect astronauts' cognition and mood from decline due to space radiation effects.McNerlin C, Guan F, Bronk L, Lei K, Grosshans D, Young DW, Gaber MW, Maletic-Savatic M. Life Sci Space Res (Amst). 2022 Nov; 2022 Jul 29. PMID: 36336363.
Modeling gene × environment interactions in PTSD using human neurons reveals diagnosis-specific glucocorticoid-induced gene expression.Seah C, Breen MS, Rusielewicz T, Bader HN, Xu C, Hunter CJ, McCarthy B, Deans PJM, Chattopadhyay M, Goldberg J, Desarnaud F, Makotkine I, Flory JD, Bierer LM, Staniskyte M, Noggle SA, Huckins LM, Paull D, Brennand KJ, Yehuda R. Nat Neurosci. 2022 Nov; 2022 Oct 20. PMID: 36266471.
MCC is a centrosomal protein that relocalizes to non-centrosomal apical sites during intestinal cell differentiation.Tomaz LB, Liu BA, Meroshini M, Ong SLM, Tan EK, Tolwinski NS, Williams CS, Gingras AC, Leushacke M, Dunn NR. J Cell Sci. 2022 Nov 1; 2022 Oct 28. PMID: 36217793.
Treatment Options for Recurrent Primary CNS Lymphoma.Kaulen LD, Baehring JM. Curr Treat Options Oncol. 2022 Nov; 2022 Oct 7. PMID: 36205806.
The druggable transcription factor Fli-1 regulates T cell immunity and tolerance in graft-versus-host disease.Schutt SD, Wu Y, Kharel A, Bastian D, Choi HJ, Hanief Sofi M, Mealer C, McDaniel Mims B, Nguyen H, Liu C, Helke K, Cui W, Zhang X, Ben-David Y, Yu XZ. J Clin Invest. 2022 Nov 1; 2022 Nov 1. PMID: 36074578.
Disease Progression of WHIM Syndrome in an International Cohort of 66 Pediatric and Adult Patients.Geier CB, Ellison M, Cruz R, Pawar S, Leiss-Piller A, Zmajkovicova K, McNulty SM, Yilmaz M, Evans MO 2nd, Gordon S, Ujhazi B, Wiest I, Abolhassani H, Aghamohammadi A, Barmettler S, Bhar S, Bondarenko A, Bolyard AA, Buchbinder D, Cada M, Cavieres M, Connelly JA, Dale DC, Deordieva E, Dorsey MJ, Drysdale SB, Ehl S, Elfeky R, Fioredda F, Firkin F, Förster-Waldl E, Geng B, Goda V, Gonzalez-Granado L, Grunebaum E, Grzesk E, Henrickson SE, Hilfanova A, Hiwatari M, Imai C, Ip W, Jyonouchi S, Kanegane H, Kawahara Y, Khojah AM, Kim VH, Kojić M, Kołtan S, Krivan G, Langguth D, Lau YL, Leung D, Miano M, Mersyanova I, Mousallem T, Muskat M, Naoum FA, Noronha SA, Ouederni M, Ozono S, Richmond GW, Sakovich I, Salzer U, Schuetz C, Seeborg FO, Sharapova SO, Sockel K, Volokha A, von Bonin M, Warnatz K, Wegehaupt O, Weinberg GA, Wong KJ, Worth A, Yu H, Zharankova Y, Zhao X, Devlin L, Badarau A, Csomos K, Keszei M, Pereira J, Taveras AG, Beaussant-Cohen SL, Ong MS, Shcherbina A, Walter JE. J Clin Immunol. 2022 Nov; 2022 Aug 10. PMID: 35947323.
Neurospora crassa is a potential source of anti-cancer agents against breast cancer.Han R, Yang H, Ling C, Lu L. Breast Cancer. 2022 Nov; 2022 Jul 5. PMID: 35881300.
Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder.Kim IB, Lee T, Lee J, Kim J, Lee S, Koh IG, Kim JH, An JY, Lee H, Kim WK, Ju YS, Cho Y, Yu SJ, Kim SA, Oh M, Han DW, Kim E, Choi JK, Yoo HJ, Lee JH. Mol Psychiatry. 2022 Nov; 2022 Jul 15. PMID: 35840799.
Human iPSC-Vascular smooth muscle cell spheroids demonstrate size-dependent alterations in cellular viability and secretory function.Islam S, Parker J, Dash BC, Hsia HC. J Biomed Mater Res A. 2022 Nov; 2022 Jul 11. PMID: 35815599.
Toxic epidermal necrolysis-like acute graft-versus-host disease in pediatric bone marrow transplant patients: Case series and review of the literature.Sheu Song J, Huang JT, Fraile Alonso MDC, Antaya RJ, Price HN, Funk T, Francois RA, Shah SD. Pediatr Dermatol. 2022 Nov; 2022 Jun 21. PMID: 35730149.
Carnegie in 4D? Stem-cell-based models of human embryo development.Sozen B, Conkar D, Veenvliet JV. Semin Cell Dev Biol. 2022 Nov; 2022 Jun 11. PMID: 35701286.
Unlocking the Potential of Induced Pluripotent Stem Cells for Wound Healing: The Next Frontier of Regenerative Medicine.Dash BC, Korutla L, Vallabhajosyula P, Hsia HC. Adv Wound Care (New Rochelle). 2022 Nov; 2021 Jul 26. PMID: 34155919.
Impact of pre-transplant induction and consolidation cycles on AML allogeneic transplant outcomes: a CIBMTR analysis in 3113 AML patients.Boyiadzis M, Zhang MJ, Chen K, Abdel-Azim H, Abid MB, Aljurf M, Bacher U, Badar T, Badawy SM, Battiwalla M, Bejanyan N, Bhatt VR, Brown VI, Castillo P, Cerny J, Copelan EA, Craddock C, Dholaria B, Perez MAD, Ebens CL, Gale RP, Ganguly S, Gowda L, Grunwald MR, Hashmi S, Hildebrandt GC, Iqbal M, Jamy O, Kharfan-Dabaja MA, Khera N, Lazarus HM, Lin R, Modi D, Nathan S, Nishihori T, Patel SS, Pawarode A, Sharma A, Solh M, Wagner JL, Wang T, Williams KM, Winestone LE, Wirk B, Hourigan CS, Litzow M, Kebriaei P, de Lima M, Page K, Weisdorf DJ. Leukemia. 2022 Oct 30; 2022 Oct 30. PMID: 36310182.
Endometriosis-associated infertility: From pathophysiology to tailored treatment.Bonavina G, Taylor HS. Front Endocrinol (Lausanne). 2022; 2022 Oct 26. PMID: 36387918.
Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.Fulton SL, Wenderski W, Lepack AE, Eagle AL, Fanutza T, Bastle RM, Ramakrishnan A, Hays EC, Neal A, Bendl J, Farrelly LA, Al-Kachak A, Lyu Y, Cetin B, Chan JC, Tran TN, Neve RL, Roper RJ, Brennand KJ, Roussos P, Schimenti JC, Friedman AK, Shen L, Blitzer RD, Robison AJ, Crabtree GR, Maze I. Nat Commun. 2022 Oct 26; 2022 Oct 26. PMID: 36289231.
Combining stem cell rejuvenation and senescence targeting to synergistically extend lifespan.Kaur P, Otgonbaatar A, Ramamoorthy A, Chua EHZ, Harmston N, Gruber J, Tolwinski NS. Aging (Albany NY). 2022 Oct 25; 2022 Oct 25. PMID: 36287172.
Human neutrophil development and functionality are enabled in a humanized mouse model.Zheng Y, Sefik E, Astle J, Karatepe K, Öz HH, Solis AG, Jackson R, Luo HR, Bruscia EM, Halene S, Shan L, Flavell RA. Proc Natl Acad Sci U S A. 2022 Oct 25; 2022 Oct 21. PMID: 36269862.
Bile acid distributions, sex-specificity, and prognosis in colorectal cancer.Cai Y, Shen X, Lu L, Yan H, Huang H, Gaule P, Muca E, Theriot CM, Rattray Z, Rattray NJW, Lu J, Ahuja N, Zhang Y, Paty PB, Khan SA, Johnson CH. Biol Sex Differ. 2022 Oct 23; 2022 Oct 23. PMID: 36274154.
Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity.Minnie SA, Waltner OG, Ensbey KS, Nemychenkov NS, Schmidt CR, Bhise SS, Legg SRW, Campoy G, Samson LD, Kuns RD, Zhou T, Huck JD, Vuckovic S, Zamora D, Yeh A, Spencer A, Koyama M, Markey KA, Lane SW, Boeckh M, Ring AM, Furlan SN, Hill GR. Sci Immunol. 2022 Oct 21; 2022 Oct 14. PMID: 36240285.
Metabolic fingerprinting of chemotherapy-resistant prostate cancer stem cells. An untargeted metabolomic approach by liquid chromatography-mass spectrometry.Bort A, G Sánchez B, León C, Nozal L, Mora-Rodríguez JM, Castro F, Crego AL, Díaz-Laviada I. Front Cell Dev Biol. 2022; 2022 Oct 17. PMID: 36325358.
Neutrophils as drivers of vascular injury in sickle cell disease.Torres LS, Hidalgo A. Immunol Rev. 2022 Oct 17; 2022 Oct 17. PMID: 36251624.
Uterine administration of C-X-C motif chemokine ligand 12 increases the pregnancy rates in mice with induced endometriosis.Rosa-E-Silva ACJS, Mamillapalli R, Rosa-E-Silva JC, Ucar A, Schwartz J, Taylor HS. F S Sci. 2022 Oct 15; 2022 Oct 15. PMID: 36252793.
Spatial maps of T cell receptors and transcriptomes reveal distinct immune niches and interactions in the adaptive immune response.Liu S, Iorgulescu JB, Li S, Borji M, Barrera-Lopez IA, Shanmugam V, Lyu H, Morriss JW, Garcia ZN, Murray E, Reardon DA, Yoon CH, Braun DA, Livak KJ, Wu CJ, Chen F. Immunity. 2022 Oct 11. PMID: 36223726.
Bivalent mRNA vaccine booster induces robust antibody immunity against Omicron lineages BA.2, BA.2.12.1, BA.2.75 and BA.5.Fang Z, Monteiro VS, Hahn AM, Grubaugh ND, Lucas C, Chen S. Cell Discov. 2022 Oct 11; 2022 Oct 11. PMID: 36220819.
Innate type 2 immunity controls hair follicle commensalism by Demodex mites.Ricardo-Gonzalez RR, Kotas ME, O'Leary CE, Singh K, Damsky W, Liao C, Arouge E, Tenvooren I, Marquez DM, Schroeder AW, Cohen JN, Fassett MS, Lee J, Daniel SG, Bittinger K, Díaz RE, Fraser JS, Ali N, Ansel KM, Spitzer MH, Liang HE, Locksley RM. Immunity. 2022 Oct 11; 2022 Aug 30. PMID: 36044899.
Stem Cell Models for Context-Specific Modeling in Psychiatric Disorders.Seah C, Huckins LM, Brennand KJ. Biol Psychiatry. 2022 Oct 8; 2022 Oct 8. PMID: 36658083.
A pathogenic variant of TULP3 causes renal and hepatic fibrocystic disease.Jafari Khamirani H, Palicharla VR, Dastgheib SA, Dianatpour M, Imanieh MH, Tabei SS, Besse W, Mukhopadhyay S, Liem KF Jr. Front Genet. 2022; 2022 Oct 7. PMID: 36276950.
The three-dimensional landscape of cortical chromatin accessibility in Alzheimer's disease.Bendl J, Hauberg ME, Girdhar K, Im E, Vicari JM, Rahman S, Fernando MB, Townsley KG, Dong P, Misir R, Kleopoulos SP, Reach SM, Apontes P, Zeng B, Zhang W, Voloudakis G, Brennand KJ, Nixon RA, Haroutunian V, Hoffman GE, Fullard JF, Roussos P. Nat Neurosci. 2022 Oct; 2022 Sep 28. PMID: 36171428.
Developmental dynamics of RNA translation in the human brain.Duffy EE, Finander B, Choi G, Carter AC, Pritisanac I, Alam A, Luria V, Karger A, Phu W, Sherman MA, Assad EG, Pajarillo N, Khitun A, Crouch EE, Ganesh S, Chen J, Berger B, Sestan N, O'Donnell-Luria A, Huang EJ, Griffith EC, Forman-Kay JD, Moses AM, Kalish BT, Greenberg ME. Nat Neurosci. 2022 Oct; 2022 Sep 28. PMID: 36171426.
Population-level variation in enhancer expression identifies disease mechanisms in the human brain.Dong P, Hoffman GE, Apontes P, Bendl J, Rahman S, Fernando MB, Zeng B, Vicari JM, Zhang W, Girdhar K, Townsley KG, Misir R, Brennand KJ, Haroutunian V, Voloudakis G, Fullard JF, Roussos P. Nat Genet. 2022 Oct; 2022 Sep 26. PMID: 36163279.
Publisher Correction: Brain charts for the human lifespan.Bethlehem RAI, Seidlitz J, White SR, Vogel JW, Anderson KM, Adamson C, Adler S, Alexopoulos GS, Anagnostou E, Areces-Gonzalez A, Astle DE, Auyeung B, Ayub M, Bae J, Ball G, Baron-Cohen S, Beare R, Bedford SA, Benegal V, Beyer F, Blangero J, Blesa Cábez M, Boardman JP, Borzage M, Bosch-Bayard JF, Bourke N, Calhoun VD, Chakravarty MM, Chen C, Chertavian C, Chetelat G, Chong YS, Cole JH, Corvin A, Costantino M, Courchesne E, Crivello F, Cropley VL, Crosbie J, Crossley N, Delarue M, Delorme R, Desrivieres S, Devenyi GA, Di Biase MA, Dolan R, Donald KA, Donohoe G, Dunlop K, Edwards AD, Elison JT, Ellis CT, Elman JA, Eyler L, Fair DA, Feczko E, Fletcher PC, Fonagy P, Franz CE, Galan-Garcia L, Gholipour A, Giedd J, Gilmore JH, Glahn DC, Goodyer IM, Grant PE, Groenewold NA, Gunning FM, Gur RE, Gur RC, Hammill CF, Hansson O, Hedden T, Heinz A, Henson RN, Heuer K, Hoare J, Holla B, Holmes AJ, Holt R, Huang H, Im K, Ipser J, Jack CR Jr, Jackowski AP, Jia T, Johnson KA, Jones PB, Jones DT, Kahn RS, Karlsson H, Karlsson L, Kawashima R, Kelley EA, Kern S, Kim KW, Kitzbichler MG, Kremen WS, Lalonde F, Landeau B, Lee S, Lerch J, Lewis JD, Li J, Liao W, Liston C, Lombardo MV, Lv J, Lynch C, Mallard TT, Marcelis M, Markello RD, Mathias SR, Mazoyer B, McGuire P, Meaney MJ, Mechelli A, Medic N, Misic B, Morgan SE, Mothersill D, Nigg J, Ong MQW, Ortinau C, Ossenkoppele R, Ouyang M, Palaniyappan L, Paly L, Pan PM, Pantelis C, Park MM, Paus T, Pausova Z, Paz-Linares D, Pichet Binette A, Pierce K, Qian X, Qiu J, Qiu A, Raznahan A, Rittman T, Rodrigue A, Rollins CK, Romero-Garcia R, Ronan L, Rosenberg MD, Rowitch DH, Salum GA, Satterthwaite TD, Schaare HL, Schachar RJ, Schultz AP, Schumann G, Schöll M, Sharp D, Shinohara RT, Skoog I, Smyser CD, Sperling RA, Stein DJ, Stolicyn A, Suckling J, Sullivan G, Taki Y, Thyreau B, Toro R, Traut N, Tsvetanov KA, Turk-Browne NB, Tuulari JJ, Tzourio C, Vachon-Presseau É, Valdes-Sosa MJ, Valdes-Sosa PA, Valk SL, van Amelsvoort T, Vandekar SN, Vasung L, Victoria LW, Villeneuve S, Villringer A, Vértes PE, Wagstyl K, Wang YS, Warfield SK, Warrier V, Westman E, Westwater ML, Whalley HC, Witte AV, Yang N, Yeo B, Yun H, Zalesky A, Zar HJ, Zettergren A, Zhou JH, Ziauddeen H, Zugman A, Zuo XN, Bullmore ET, Alexander-Bloch AF. Nature. 2022 Oct. PMID: 36151472.
Innovative Designs and Logistical Considerations for Expedited Clinical Development of Combination Disease-Modifying Treatments for Type 1 Diabetes.Anderson RL, DiMeglio LA, Mander AP, Dayan CM, Linsley PS, Herold KC, Marinac M, Ahmed ST. Diabetes Care. 2022 Oct 1. PMID: 36150059.
Bioenergy sorghum stem growth regulation: intercalary meristem localization, development, and gene regulatory network analysis.Yu KMJ, Oliver J, McKinley B, Weers B, Fabich HT, Evetts N, Conradi MS, Altobelli SA, Marshall-Colon A, Mullet J. Plant J. 2022 Oct; 2022 Sep 22. PMID: 36038985.
The transition phase: preparing to launch a laboratory.McKinley KL, Didychuk AL, Nicholas DA, Termini CM. Trends Biochem Sci. 2022 Oct; 2022 May 26. PMID: 35644775.
Correction to: Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients.Hashem H, Bucciol G, Ozen S, Unal S, Bozkaya IO, Akarsu N, Taskinen M, Koskenvuo M, Saarela J, Dimitrova D, Hickstein DD, Hsu AP, Holland SM, Krance R, Sasa G, Kumar AR, Müller I, de Sousa MA, Delafontaine S, Moens L, Babor F, Barzaghi F, Cicalese MP, Bredius R, van Montfrans J, Baretta V, Cesaro S, Stepensky P, Benedicte N, Moshous D, Le Guenno G, Boutboul D, Dalal J, Brooks JP, Dokmeci E, Dara J, Lucas CL, Hambleton S, Wilson K, Jolles S, Koc Y, Güngör T, Schnider C, Candotti F, Steinmann S, Schulz A, Chambers C, Hershfield M, Ombrello A, Kanakry JA, Meyts I. J Clin Immunol. 2022 Oct. PMID: 35499644.
Strategic use of organoids and organs-on-chip as biomimetic tools.Santos AK, Scalzo S, de Souza RTV, Santana PHG, Marques BL, Oliveira LF, Filho DM, Kihara AH, da Costa Santiago H, Parreira RC, Birbrair A, Ulrich H, Resende RR. Semin Cell Dev Biol. 2022 Sep 30; 2022 Sep 30. PMID: 36192310.