Recent Publications

2021

• Identification and validation of a five-lncRNA signature for predicting survival with targeted drug candidates in ovarian cancer.Lin N, Lin JZ, Tanaka Y, Sun P, Zhou X. Bioengineered. 2021 Dec. PMID: 34224310.
• Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients.Hashem H, Bucciol G, Ozen S, Unal S, Bozkaya IO, Akarsu N, Taskinen M, Koskenvuo M, Saarela J, Dimitrova D, Hickstein DD, Hsu AP, Holland SM, Krance R, Sasa G, Kumar AR, Müller I, de Sousa MA, Delafontaine S, Moens L, Babor F, Barzaghi F, Cicalese MP, Bredius R, van Montfrans J, Baretta V, Cesaro S, Stepensky P, Benedicte N, Moshous D, Le Guenno G, Boutboul D, Dalal J, Brooks JP, Dokmeci E, Dara J, Lucas CL, Hambleton S, Wilson K, Jolles S, Koc Y, Güngör T, Schnider C, Candotti F, Steinmann S, Schulz A, Chambers C, Hershfield M, Ombrello A, Kanakry JA, Meyts I. J Clin Immunol. 2021 Oct; 2021 Jul 29. PMID: 34324127.
• Radial Glial Cells: New Views on Old Questions.Arellano JI, Morozov YM, Micali N, Rakic P. Neurochem Res. 2021 Oct; 2021 Mar 16. PMID: 33725233.
• tRNA-like leader-trailer interaction promotes 3'-end maturation of MALAT1.Torabi SF, DeGregorio SJ, Steitz JA. RNA. 2021 Oct; 2021 Jul 12. PMID: 34253686.
• CTCFL expression is associated with cerebral vascular abnormalities.Sati L, Soygur B, Goksu E, Bassorgun CI, McGrath J. Tissue Cell. 2021 Oct; 2021 Mar 16. PMID: 33756271.
• The roles of epigenetics in cancer progression and metastasis.Chen JF, Yan Q. Biochem J. 2021 Sep 17. PMID: 34520519.
• Emergence of an early SARS-CoV-2 epidemic in the United States.Zeller M, Gangavarapu K, Anderson C, Smither AR, Vanchiere JA, Rose R, Snyder DJ, Dudas G, Watts A, Matteson NL, Robles-Sikisaka R, Marshall M, Feehan AK, Sabino-Santos G Jr, Bell-Kareem AR, Hughes LD, Alkuzweny M, Snarski P, Garcia-Diaz J, Scott RS, Melnik LI, Klitting R, McGraw M, Belda-Ferre P, DeHoff P, Sathe S, Marotz C, Grubaugh ND, Nolan DJ, Drouin AC, Genemaras KJ, Chao K, Topol S, Spencer E, Nicholson L, Aigner S, Yeo GW, Farnaes L, Hobbs CA, Laurent LC, Knight R, Hodcroft EB, Khan K, Fusco DN, Cooper VS, Lemey P, Gardner L, Lamers SL, Kamil JP, Garry RF, Suchard MA, Andersen KG. Cell. 2021 Sep 16; 2021 Jul 27. PMID: 34508652.
• Personalized models of heterogeneous 3D epithelial tumor microenvironments: Ovarian cancer as a model.Horst EN, Bregenzer ME, Mehta P, Snyder CS, Repetto T, Yang-Hartwich Y, Mehta G. Acta Biomater. 2021 Sep 15; 2021 Apr 30. PMID: 33940195.
• Refusing blood transfusions from COVID-19-vaccinated donors: are we repeating history?Jacobs JW, Bibb LA, Savani BN, Booth GS. Br J Haematol. 2021 Sep 15; 2021 Sep 15. PMID: 34523736.
• Cystin genetic variants cause autosomal recessive polycystic kidney disease associated with altered Myc expression.Yang C, Harafuji N, O'Connor AK, Kesterson RA, Watts JA, Majmundar AJ, Braun DA, Lek M, Laricchia KM, Fathy HM, Mane S, Shril S, Hildebrandt F, Guay-Woodford LM. Sci Rep. 2021 Sep 14; 2021 Sep 14. PMID: 34521872.
• Integrin αEβ7⁺ T cells direct intestinal stem cell fate decisions via adhesion signaling.Chen S, Zheng Y, Ran X, Du H, Feng H, Yang L, Wen Y, Lin C, Wang S, Huang M, Yan Z, Wu D, Wang H, Ge G, Zeng A, Zeng YA, Chen J. Cell Res. 2021 Sep 13; 2021 Sep 13. PMID: 34518654.
• Characterization of Bone Marrow Progenitor Cell Uterine Engraftment and Transdifferentiation.Mamillapalli R, Mutlu L, Taylor HS. Reprod Sci. 2021 Sep 13; 2021 Sep 13. PMID: 34515983.
• Life Expectancy After Allogeneic Stem Cell Transplant-In It for the Long Haul?Gowda L, Seropian S. JAMA Oncol. 2021 Sep 9; 2021 Sep 9. PMID: 34499090.
• An mRNA assay system demonstrates proteasomal-specific degradation contributes to cardiomyopathic phospholamban null mutation.Rohner E, Witman N, Sohlmer J, De Genst E, Louch WE, Sahara M, Chien KR. Mol Med. 2021 Sep 8; 2021 Sep 8. PMID: 34496741.
• Induction of dopaminergic neurons for neuronal subtype-specific modeling of psychiatric disease risk.Powell SK, O'Shea C, Townsley K, Prytkova I, Dobrindt K, Elahi R, Iskhakova M, Lambert T, Valada A, Liao W, Ho SM, Slesinger PA, Huckins LM, Akbarian S, Brennand KJ. Mol Psychiatry. 2021 Sep 7; 2021 Sep 7. PMID: 34493831.
• Loss of crossbridge inhibition drives pathological cardiac hypertrophy in patients harboring the TPM1 E192K mutation.Sewanan LR, Park J, Rynkiewicz MJ, Racca AW, Papoutsidakis N, Schwan J, Jacoby DL, Moore JR, Lehman W, Qyang Y, Campbell SG. J Gen Physiol. 2021 Sep 6; 2021 Jul 28. PMID: 34319370.
• Stop codon readthrough alters the activity of a POU/Oct transcription factor during Drosophila development.Zhao Y, Lindberg BG, Esfahani SS, Tang X, Piazza S, Engström Y. BMC Biol. 2021 Sep 3; 2021 Sep 3. PMID: 34479564.
• An MST4-pβ-Catenin^Thr40 Signaling Axis Controls Intestinal Stem Cell and Tumorigenesis.Zhang H, Lin M, Dong C, Tang Y, An L, Ju J, Wen F, Chen F, Wang M, Wang W, Chen M, Zhao Y, Li J, Hou SX, Lin X, Hu L, Bu W, Wu D, Li L, Jiao S, Zhou Z. Adv Sci (Weinh). 2021 Sep; 2021 Jul 8. PMID: 34240584.
• Comprehensive phenotyping of erythropoiesis in human bone marrow: Evaluation of normal and ineffective erythropoiesis.Yan H, Ali A, Blanc L, Narla A, Lane JM, Gao E, Papoin J, Hale J, Hillyer CD, Taylor N, Gallagher PG, Raza A, Kinet S, Mohandas N. Am J Hematol. 2021 Sep 1; 2021 Jun 3. PMID: 34021930.
• Correction to: Impact of depth of clinical response on outcomes of acute myeloid leukemia patients in first complete remission who undergo allogeneic hematopoietic cell transplantation.Percival ME, Wang HL, Zhang MJ, Saber W, de Lima M, Litzow M, Kebriaei P, Abdel-Azim H, Adekola K, Aljurf M, Bacher U, Badawy SM, Beitinjaneh A, Bejanyan N, Bhatt V, Byrne M, Cahn JY, Castillo P, Chao N, Chhabra S, Copelan E, Cutler C, DeFilipp Z, Dias A, Diaz MA, Estey E, Farhadfar N, Frangoul HA, Freytes CO, Gale RP, Ganguly S, Gowda L, Grunwald M, Hossain N, Kamble RT, Kanakry CG, Kansagra A, Kharfan-Dabaja MA, Krem M, Lazarus HM, Lee JW, Liesveld JL, Lin R, Liu H, McGuirk J, Munker R, Murthy HS, Nathan S, Nishihori T, Olsson RF, Palmisiano N, Passweg JR, Prestidge T, Ringdén O, Rizzieri DA, Rybka WB, Savoie ML, Schultz KR, Seo S, Sharma A, Solh M, Strair R, van der Poel M, Verdonck LF, Yared JA, Weisdorf D, Sandmaier BM. Bone Marrow Transplant. 2021 Sep. PMID: 34017072.
• Impact of depth of clinical response on outcomes of acute myeloid leukemia patients in first complete remission who undergo allogeneic hematopoietic cell transplantation.Percival ME, Wang HL, Zhang MJ, Saber W, de Lima M, Litzow M, Kebriaei P, Abdel-Azim H, Adekola K, Aljurf M, Bacher U, Badawy SM, Beitinjaneh A, Bejanyan N, Bhatt V, Byrne M, Cahn JY, Castillo P, Chao N, Chhabra S, Copelan E, Cutler C, DeFilipp Z, Dias A, Diaz MA, Estey E, Farhadfar N, Frangoul HA, Freytes CO, Gale RP, Ganguly S, Gowda L, Grunwald M, Hossain N, Kamble RT, Kanakry CG, Kansagra A, Kharfan-Dabaja MA, Krem M, Lazarus HM, Lee JW, Liesveld JL, Lin R, Liu H, McGuirk J, Munker R, Murthy HS, Nathan S, Nishihori T, Olsson RF, Palmisiano N, Passweg JR, Prestidge T, Ringdén O, Rizzieri DA, Rybka WB, Savoie ML, Schultz KR, Seo S, Sharma A, Solh M, Strair R, van der Poel M, Verdonck LF, Yared JA, Weisdorf D, Sandmaier BM. Bone Marrow Transplant. 2021 Sep; 2021 Apr 16. PMID: 33864019.
• Management of the Older Patient with Myelodysplastic Syndrome.Shallis RM, Zeidan AM. Drugs Aging. 2021 Sep; 2021 Aug 3. PMID: 34342860.
• New nonchemotherapy treatment options for cutaneous T-cell lymphomas.Xu S, Foss F. Expert Rev Anticancer Ther. 2021 Sep; 2021 Jul 27. PMID: 33554707.
• Small extracellular vesicles released by infused mesenchymal stromal cells target M2 macrophages and promote TGF-β upregulation, microvascular stabilization and functional recovery in a rodent model of severe spinal cord injury.Nakazaki M, Morita T, Lankford KL, Askenase PW, Kocsis JD. J Extracell Vesicles. 2021 Sep. PMID: 34478241.
• Evidence for synergy between sarcomeres and fibroblasts in an in vitro model of myocardial reverse remodeling.Shen S, Sewanan LR, Campbell SG. J Mol Cell Cardiol. 2021 Sep; 2021 May 14. PMID: 33992697.
• Association of Diet Quality With Prevalence of Clonal Hematopoiesis and Adverse Cardiovascular Events.Bhattacharya R, Zekavat SM, Uddin MM, Pirruccello J, Niroula A, Gibson C, Griffin GK, Libby P, Ebert BL, Bick A, Natarajan P. JAMA Cardiol. 2021 Sep 1. PMID: 34106216.
• Genomic and evolutionary classification of lung cancer in never smokers.Zhang T, Joubert P, Ansari-Pour N, Zhao W, Hoang PH, Lokanga R, Moye AL, Rosenbaum J, Gonzalez-Perez A, Martínez-Jiménez F, Castro A, Muscarella LA, Hofman P, Consonni D, Pesatori AC, Kebede M, Li M, Gould Rothberg BE, Peneva I, Schabath MB, Poeta ML, Costantini M, Hirsch D, Heselmeyer-Haddad K, Hutchinson A, Olanich M, Lawrence SM, Lenz P, Duggan M, Bhawsar PMS, Sang J, Kim J, Mendoza L, Saini N, Klimczak LJ, Islam SMA, Otlu B, Khandekar A, Cole N, Stewart DR, Choi J, Brown KM, Caporaso NE, Wilson SH, Pommier Y, Lan Q, Rothman N, Almeida JS, Carter H, Ried T, Kim CF, Lopez-Bigas N, Garcia-Closas M, Shi J, Bossé Y, Zhu B, Gordenin DA, Alexandrov LB, Chanock SJ, Wedge DC, Landi MT. Nat Genet. 2021 Sep; 2021 Sep 6. PMID: 34493867.
• Understanding neural stem cell regulation in vivo and applying the insights to cell therapy for strokes.Genet N, Hirschi KK. Regen Med. 2021 Sep; 2021 Sep 9. PMID: 34498495.
• Transfusion practices for pediatric oncology and hematopoietic stem cell transplantation patients: Data from the National Heart Lung and Blood Institute Recipient Epidemiology and Donor Evaluation Study-III (REDS-III).Goel R, Nellis ME, Karam O, Hanson SJ, Tormey CA, Patel RM, Birch R, Sachais BS, Sola-Visner MC, Hauser RG, Luban NLC, Gottschall J, Josephson CD, Hendrickson JE, Karafin MS. Transfusion. 2021 Sep; 2021 Aug 29. PMID: 34455598.
• The tight junction protein ZO-1 is dispensable for barrier function but critical for effective mucosal repair.Kuo WT, Zuo L, Odenwald MA, Madha S, Singh G, Gurniak CB, Abraham C, Turner JR. Gastroenterology. 2021 Aug 31; 2021 Aug 31. PMID: 34478742.
• Amnion signals are essential for mesoderm formation in primates.Yang R, Goedel A, Kang Y, Si C, Chu C, Zheng Y, Chen Z, Gruber PJ, Xiao Y, Zhou C, Witman N, Eroglu E, Leung CY, Chen Y, Fu J, Ji W, Lanner F, Niu Y, Chien KR. Nat Commun. 2021 Aug 26; 2021 Aug 26. PMID: 34446705.
• Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions.Girskis KM, Stergachis AB, DeGennaro EM, Doan RN, Qian X, Johnson MB, Wang PP, Sejourne GM, Nagy MA, Pollina EA, Sousa AMM, Shin T, Kenny CJ, Scotellaro JL, Debo BM, Gonzalez DM, Rento LM, Yeh RC, Song JHT, Beaudin M, Fan J, Kharchenko PV, Sestan N, Greenberg ME, Walsh CA. Neuron. 2021 Aug 25; 2021 Aug 25. PMID: 34478631.
• Biallelic PI4KA variants cause neurological, intestinal and immunological disease.Salter CG, Cai Y, Lo B, Helman G, Taylor H, McCartney A, Leslie JS, Accogoli A, Zara F, Traverso M, Fasham J, Lees JA, Ferla M, Chioza BA, Wenger O, Scott E, Cross HE, Crawford J, Warshawsky I, Keisling M, Agamanolis D, Melver CW, Cox H, Elawad M, Marton T, Wakeling M, Holzinger D, Tippelt S, Munteanu M, Valcheva D, Deal C, Van Meerbeke S, Vockley CW, Butte MJ, Acar U, van der Knaap MS, Korenke GC, Kotzaeridou U, Balla T, Simons C, Uhlig HH, Crosby AH, De Camilli P, Wolf NI, Baple EL. Brain. 2021 Aug 20; 2021 Aug 20. PMID: 34415310.
• Metabolic decisions in development and disease-a Keystone Symposia report.Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, Teleman A, Tu WB, Garrett WS, Miguel-Aliaga I, Perrimon N, Hooper LV, Walhout AJM, Wei W, Alexandrov T, Erez A, Ralser M, Rabinowitz JD, Hemalatha A, Gutiérrez-Pérez P, Chandel NS, Rutter J, Locasale JW, Landoni JC, Christofk H. Ann N Y Acad Sci. 2021 Aug 19; 2021 Aug 19. PMID: 34414571.
• Fungal infections in hematopoietic stem-cell transplant patients: a review of epidemiology, diagnosis, and management.Rahi MS, Jindal V, Pednekar P, Parekh J, Gunasekaran K, Sharma S, Stender M, Jaiyesimi IA. Ther Adv Infect Dis. 2021 Jan-Dec; 2021 Aug 19. PMID: 34434551.
• Clinical and imaging outcomes after intrathecal injection of umbilical cord tissue mesenchymal stem cells in cerebral palsy: a randomized double-blind sham-controlled clinical trial.Amanat M, Majmaa A, Zarrabi M, Nouri M, Akbari MG, Moaiedi AR, Ghaemi O, Zamani F, Najafi S, Badv RS, Vosough M, Hamidieh AA, Salehi M, Montazerlotfelahi H, Tavasoli AR, Heidari M, Mohebi H, Fatemi A, Garakani A, Ashrafi MR. Stem Cell Res Ther. 2021 Aug 6; 2021 Aug 6. PMID: 34362453.
• The p53 transcriptional response across tumor types reveals core and senescence-specific signatures modulated by long noncoding RNAs.Tesfaye E, Martinez-Terroba E, Bendor J, Winkler L, Olivero C, Chen K, Feldser DM, Zamudio JR, Dimitrova N. Proc Natl Acad Sci U S A. 2021 Aug 3. PMID: 34326251.
• Clinicopathologic Features of Tissue Granulomas in Transplant Recipients: A Single Center Study in a Nontuberculosis Endemic Region.Nussbaum EZ, Patel KK, Assi R, Raad RA, Malinis M, Azar MM. Arch Pathol Lab Med. 2021 Aug 1. PMID: 33290524.
• Multi-institutional study evaluating clinical outcome with allogeneic hematopoietic stem cell transplantation after blinatumomab in patients with B-cell acute lymphoblastic leukemia: real-world data.Badar T, Szabo A, Litzow M, Burkart M, Yurkiewicz I, Dinner S, Hefazi M, Shallis RM, Podoltsev N, Patel AA, Curran E, Wadleigh M, Balasubramanian S, Yang J, Arslan S, Aldoss I, Mattison R, Cenin D, Siebenaller C, Advani A, Liedtke M, Atallah E. Bone Marrow Transplant. 2021 Aug; 2021 Apr 6. PMID: 33824440.
• A melanoma patient with macrophage-cancer cell hybrids in the primary tumor, a lymph node metastasis and a brain metastasis.LaBerge G, Duvall E, Grasmick Z, Haedicke K, Galan A, Pawelek J. Cancer Genet. 2021 Aug; 2021 May 28. PMID: 34166887.
• Optogenetic approaches for understanding homeostatic and degenerative processes in Drosophila.Lim WK, Kaur P, Huang H, Jo RS, Ramamoorthy A, Ng LF, Suresh J, Maisha FI, Mathuru AS, Tolwinski NS. Cell Mol Life Sci. 2021 Aug; 2021 Jul 7. PMID: 34232330.
• Applying stem cells and CRISPR engineering to uncover the etiology of schizophrenia.Michael Deans PJ, Brennand KJ. Curr Opin Neurobiol. 2021 Aug; 2021 May 16. PMID: 34010781.
• Vulnerability of cholecystokinin-expressing GABAergic interneurons in the unilateral intrahippocampal kainate mouse model of temporal lobe epilepsy.Kang YJ, Clement EM, Park IH, Greenfield LJ Jr, Smith BN, Lee SH. Exp Neurol. 2021 Aug; 2021 Apr 26. PMID: 33915166.
• Predictive value of cytoplasmic granulation patterns during in vitro fertilization in metaphase II oocytes: Part I, poor-prognosis patients.Hu J, Molinari E, Darmon S, Zhang L, Patrizio P, Barad DH, Gleicher N. Fertil Steril. 2021 Aug; 2021 Apr 15. PMID: 33865566.
• Regeneration of infarcted mouse hearts by cardiovascular tissue formed via the direct reprogramming of mouse fibroblasts.Cho J, Kim S, Lee H, Rah W, Cho HC, Kim NK, Bae S, Shin DH, Lee MG, Park IH, Tanaka Y, Shin E, Yi H, Han JW, Hwang PTJ, Jun HW, Park HJ, Cho K, Lee SW, Jung JK, Levit RD, Sussman MA, Harvey RP, Yoon YS. Nat Biomed Eng. 2021 Aug; 2021 Aug 23. PMID: 34426676.
• The ASH-ASPHO Choosing Wisely Campaign: 5 hematologic tests and treatments to question.O'Brien SH, Badawy SM, Rotz SJ, Shah MD, Makarski J, Bercovitz RS, Hogan MS, Luchtman-Jones L, Panepinto JA, Priola GM, Witmer CM, Wolfson JA, Yee M, Hicks LK. Pediatr Blood Cancer. 2021 Aug; 2021 May 28. PMID: 34047047.
• Letermovir treatment of cytomegalovirus infection or disease in solid organ and hematopoietic cell transplant recipients.Linder KA, Kovacs C, Mullane KM, Wolfe C, Clark NM, La Hoz RM, Smith J, Kotton CN, Limaye AP, Malinis M, Hakki M, Mishkin A, Gonzalez AA, Prono MD, Ostrander D, Avery R, Kaul DR. Transpl Infect Dis. 2021 Aug; 2021 Jul 20. PMID: 34251742.
• Donor-Specific Antibodies and Primary Graft Failure in Allogeneic Hematopoietic Stem Cell Transplantation: A Systematic Review and Meta-Analysis.Xie Y, Parekh J, Tang Z, Wu D, Wu X. Transplant Cell Ther. 2021 Aug; 2021 May 12. PMID: 33989833.
• Preimplantation Genetic Testing for Aneuploidy - a Castle Built on Sand.Gleicher N, Patrizio P, Brivanlou A. Trends Mol Med. 2021 Aug; 2021 Jan 11. PMID: 33446425.
• PRL3 induces polypoid giant cancer cells eliminated by PRL3-zumab to reduce tumor relapse.Thura M, Ye Z, Al-Aidaroos AQ, Xiong Q, Ong JY, Gupta A, Li J, Guo K, Ang KH, Zeng Q. Commun Biol. 2021 Jul 29; 2021 Jul 29. PMID: 34326464.
• Nuclear accumulation of CHMP7 initiates nuclear pore complex injury and subsequent TDP-43 dysfunction in sporadic and familial ALS.Coyne AN, Baskerville V, Zaepfel BL, Dickson DW, Rigo F, Bennett F, Lusk CP, Rothstein JD. Sci Transl Med. 2021 Jul 28. PMID: 34321318.
• Integrin β3 targeting biomaterial preferentially promotes secretion of bFGF and viability of iPSC-derived vascular smooth muscle cells.Dash BC, Duan K, Kyriakides TR, Hsia HC. Biomater Sci. 2021 Jul 27. PMID: 34190227.
• Methylation of dual-specificity phosphatase 4 controls cell differentiation.Su H, Jiang M, Senevirathne C, Aluri S, Zhang T, Guo H, Xavier-Ferrucio J, Jin S, Tran NT, Liu SM, Sun CW, Zhu Y, Zhao Q, Chen Y, Cable L, Shen Y, Liu J, Qu CK, Han X, Klug CA, Bhatia R, Chen Y, Nimer SD, Zheng YG, Iancu-Rubin C, Jin J, Deng H, Krause DS, Xiang J, Verma A, Luo M, Zhao X. Cell Rep. 2021 Jul 27. PMID: 34320342.
• Unlocking the Potential of Induced Pluripotent Stem Cells for Wound Healing: The Next Frontier of Regenerative Medicine.Dash BC, Korutla L, Vallabhajosyula P, Hsia HC. Adv Wound Care (New Rochelle). 2021 Jul 26; 2021 Jul 26. PMID: 34155919.
• Fibroblasts: Origins, definitions, and functions in health and disease.Plikus MV, Wang X, Sinha S, Forte E, Thompson SM, Herzog EL, Driskell RR, Rosenthal N, Biernaskie J, Horsley V. Cell. 2021 Jul 22. PMID: 34297930.
• Predictive value of cytoplasmic granulation patterns during in vitro fertilization in metaphase II oocytes: part II, donor oocyte cycles.Hu J, Molinari E, Darmon SK, Zhang L, Patrizio P, Barad DH, Gleicher N. Fertil Steril. 2021 Jul 19; 2021 Jul 19. PMID: 34294452.
• Efficacy and safety of mogamulizumab by patient baseline blood tumour burden: a post hoc analysis of the MAVORIC trial.Cowan RA, Scarisbrick JJ, Zinzani PL, Nicolay JP, Sokol L, Pinter-Brown L, Quaglino P, Iversen L, Dummer R, Musiek A, Foss F, Ito T, Rosen JP, Medley MC. J Eur Acad Dermatol Venereol. 2021 Jul 17; 2021 Jul 17. PMID: 34273208.
• Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease.Salvi PS, Cowles RA. Cells. 2021 Jul 14; 2021 Jul 14. PMID: 34359944.
• Human multipotent adult progenitor cells effectively reduce graft-vs-host disease while preserving graft-vs-leukemia activity.Metheny L, Eid S, Wuttisarnwattana P, Auletta JJ, Liu C, Van Dervort A, Paez C, Lee Z, Wilson D, Lazarus HM, Deans R, Vant Hof W, Ktena Y, Cooke KR. Stem Cells. 2021 Jul 13; 2021 Jul 13. PMID: 34255899.
• Genomics of human congenital hydrocephalus.Kundishora AJ, Singh AK, Allington G, Duy PQ, Ryou J, Alper SL, Jin SC, Kahle KT. Childs Nerv Syst. 2021 Jul 7; 2021 Jul 7. PMID: 34232380.
• COVID-19: Unmasking Emerging SARS-CoV-2 Variants, Vaccines and Therapeutic Strategies.Raman R, Patel KJ, Ranjan K. Biomolecules. 2021 Jul 6; 2021 Jul 6. PMID: 34356617.
• Constrained chromatin accessibility in PU.1-mutated agammaglobulinemia patients.Le Coz C, Nguyen DN, Su C, Nolan BE, Albrecht AV, Xhani S, Sun D, Demaree B, Pillarisetti P, Khanna C, Wright F, Chen PA, Yoon S, Stiegler AL, Maurer K, Garifallou JP, Rymaszewski A, Kroft SH, Olson TS, Seif AE, Wertheim G, Grant SFA, Vo LT, Puck JM, Sullivan KE, Routes JM, Zakharova V, Shcherbina A, Mukhina A, Rudy NL, Hurst ACE, Atkinson TP, Boggon TJ, Hakonarson H, Abate AR, Hajjar J, Nicholas SK, Lupski JR, Verbsky J, Chinn IK, Gonzalez MV, Wells AD, Marson A, Poon GMK, Romberg N. J Exp Med. 2021 Jul 5; 2021 May 5. PMID: 33951726.
• Bone marrow-derived progenitor cells contribute to remodeling of the postpartum uterus.Tal R, Kisa J, Abuwala N, Kliman HJ, Shaikh S, Chen AY, Lyu F, Taylor HS. Stem Cells. 2021 Jul 5; 2021 Jul 5. PMID: 34224633.
• Genetic Determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response In Vivo.Foggetti G, Li C, Cai H, Hellyer JA, Lin WY, Ayeni D, Hastings K, Choi J, Wurtz A, Andrejka L, Maghini DG, Rashleigh N, Levy S, Homer R, Gettinger SN, Diehn M, Wakelee HA, Petrov DA, Winslow MM, Politi K. Cancer Discov. 2021 Jul; 2021 Mar 11. PMID: 33707235.
• Apical CLC-2 in retinal pigment epithelium is crucial for survival of the outer retina.Hanke-Gogokhia C, Lehmann GL, Benedicto I, de la Fuente-Ortega E, Arshavsky VY, Schreiner R, Rodriguez-Boulan E. FASEB J. 2021 Jul. PMID: 34085737.
• Jazf1 acts as a regulator of insulin-producing β-cell differentiation in induced pluripotent stem cells and glucose homeostasis in mice.Park SJ, Kwon W, Park S, Jeong J, Kim D, Jang S, Kim SY, Sung Y, Kim MO, Choi SK, Ryoo ZY. FEBS J. 2021 Jul; 2021 Apr 23. PMID: 33555104.
• Comparative effects of fluconazole, posaconazole, and isavuconazole upon tacrolimus and cyclosporine serum concentrations.Gu TM, Lewis JS 2nd, Le H, Bubalo JS. J Oncol Pharm Pract. 2021 Jul 1; 2021 Jul 1. PMID: 34192963.
• Pathogenic SPTBN1 variants cause an autosomal dominant neurodevelopmental syndrome.Cousin MA, Creighton BA, Breau KA, Spillmann RC, Torti E, Dontu S, Tripathi S, Ajit D, Edwards RJ, Afriyie S, Bay JC, Harper KM, Beltran AA, Munoz LJ, Falcon Rodriguez L, Stankewich MC, Person RE, Si Y, Normand EA, Blevins A, May AS, Bier L, Aggarwal V, Mancini GMS, van Slegtenhorst MA, Cremer K, Becker J, Engels H, Aretz S, MacKenzie JJ, Brilstra E, van Gassen KLI, van Jaarsveld RH, Oegema R, Parsons GM, Mark P, Helbig I, McKeown SE, Stratton R, Cogne B, Isidor B, Cacheiro P, Smedley D, Firth HV, Bierhals T, Kloth K, Weiss D, Fairley C, Shieh JT, Kritzer A, Jayakar P, Kurtz-Nelson E, Bernier RA, Wang T, Eichler EE, van de Laar IMBH, McConkie-Rosell A, McDonald MT, Kemppainen J, Lanpher BC, Schultz-Rogers LE, Gunderson LB, Pichurin PN, Yoon G, Zech M, Jech R, Winkelmann J, Beltran AS, Zimmermann MT, Temple B, Moy SS, Klee EW, Tan QK, Lorenzo DN. Nat Genet. 2021 Jul; 2021 Jul 1. PMID: 34211179.
• Breaking the Age Barrier: Physicians' Perceptions of Candidacy for Allogeneic Hematopoietic Cell Transplantation in Older Adults.Mishra A, Preussler JM, Bhatt VR, Bredeson C, Chhabra S, D'Souza A, Dahi PB, Hacker ED, Gowda L, Hashmi SK, Howard DS, Jakubowski A, Jayani R, Koll T, Lin RJ, Olin RL, Popat UR, Rodriguez C, Rosko A, Sabloff M, Sorror ML, Sung AD, Ustun C, Wood WA, Burns L, Artz A. Transplant Cell Ther. 2021 Jul; 2021 Apr 6. PMID: 33836312.
• A Machine Learning Model to Successfully Predict Future Diagnosis of Chronic Myelogenous Leukemia With Retrospective Electronic Health Records Data.Hauser RG, Esserman D, Beste LA, Ong SY, Colomb DG, Bhargava A, Wadia R, Rose MG. Am J Clin Pathol. 2021 Jun 29; 2021 Jun 29. PMID: 34184028.
• Spatial transcriptome profiling by MERFISH reveals fetal liver hematopoietic stem cell niche architecture.Lu Y, Liu M, Yang J, Weissman SM, Pan X, Katz SG, Wang S. Cell Discov. 2021 Jun 29; 2021 Jun 29. PMID: 34183665.
• In silico analysis of the transcriptional regulatory logic of neuronal identity specification throughout the C. elegans nervous system.Glenwinkel L, Taylor SR, Langebeck-Jensen K, Pereira L, Reilly MB, Basavaraju M, Rafi I, Yemini E, Pocock R, Sestan N, Hammarlund M, Miller DM 3rd, Hobert O. Elife. 2021 Jun 24; 2021 Jun 24. PMID: 34165430.
• Bone Marrow-Derived VSELs Engraft as Lung Epithelial Progenitor Cells after Bleomycin-Induced Lung Injury.Ciechanowicz AK, Sielatycka K, Cymer M, Skoda M, Suszyńska M, Bujko K, Ratajczak MZ, Krause DS, Kucia M. Cells. 2021 Jun 22; 2021 Jun 22. PMID: 34206516.
• Understanding totipotency: A role for alternative splicing.De Los Angeles A, Liu P. Dev Cell. 2021 Jun 21. PMID: 34157304.
• Bartonellosis in transplant recipients: A retrospective single center experience.Pischel L, Radcliffe C, Vilchez GA, Charifa A, Zhang XC, Grant M. World J Transplant. 2021 Jun 18. PMID: 34164299.
• Maternal Piwi Regulates Primordial Germ Cell Development to Ensure the Fertility of Female Progeny in Drosophila.Gonzalez LE, Tang X, Lin H. Genetics. 2021 Jun 17; 2021 Jun 17. PMID: 34142134.
• Baseline Differences in Long-term Survivors and Nonsurvivors of the Colorado/Columbia Fetal Implant Trial.McRae C, Dunk M, Russell D, Ellgring H, Stern Y, Greene P, Fahn S, Henchcliffe C. J Int Neuropsychol Soc. 2021 Jun 14; 2021 Jun 14. PMID: 34121635.
• Diversity in responses to oncolytic Lassa-vesicular stomatitis virus in patient-derived glioblastoma cells.Kim TE, Puckett S, Zhang K, Herpai DM, Ornelles DA, Davis JN, van den Pol AN, Debinski W, Lyles DS. Mol Ther Oncolytics. 2021 Sep 24; 2021 Jun 12. PMID: 34514102.
• Targeted PI3K/AKT-hyperactivation induces cell death in chronic lymphocytic leukemia.Ecker V, Stumpf M, Brandmeier L, Neumayer T, Pfeuffer L, Engleitner T, Ringshausen I, Nelson N, Jücker M, Wanninger S, Zenz T, Wendtner C, Manske K, Steiger K, Rad R, Müschen M, Ruland J, Buchner M. Nat Commun. 2021 Jun 10; 2021 Jun 10. PMID: 34112805.
• AXL inhibition in macrophages stimulates host-versus-leukemia immunity and eradicates naive and treatment resistant leukemia.Tirado-Gonzalez I, Descot A, Soetopo D, Nevmerzhitskaya A, Schaffer A, Kur IM, Czlonka E, Wachtel C, Tsoukala I, Muller L, Schafer AL, Weitmann M, Dinse P, Alberto E, Buck MC, Landry JJM, Baying B, Slotta-Huspenina J, Roesler J, Harter PN, Kubasch AS, Meinel J, Elwakeel E, Strack E, Tran Quang C, Abdel-Wahab O, Schmitz M, Weigert A, Schmid T, Platzbecker U, Benes V, Ghysdael J, Bonig H, Gotze KS, Rothlin CV, Ghosh S, Medyouf H. Cancer Discov. 2021 Jun 8; 2021 Jun 8. PMID: 34103328.
• Systems genetics in diversity outbred mice inform BMD GWAS and identify determinants of bone strength.Al-Barghouthi BM, Mesner LD, Calabrese GM, Brooks D, Tommasini SM, Bouxsein ML, Horowitz MC, Rosen CJ, Nguyen K, Haddox S, Farber EA, Onengut-Gumuscu S, Pomp D, Farber CR. Nat Commun. 2021 Jun 7; 2021 Jun 7. PMID: 34099702.
• Long-term neurocognitive and quality of life outcomes in survivors of pediatric hematopoietic cell transplant.Wu NL, Krull KR, Cushing-Haugen KL, Ullrich NJ, Kadan-Lottick NS, Lee SJ, Chow EJ. J Cancer Surviv. 2021 Jun 4; 2021 Jun 4. PMID: 34086185.
• Epidemiology, Risk Factors, and Outcomes of Diffuse Alveolar Hemorrhage After Hematopoietic Stem Cell Transplantation.Zhang Z, Wang C, Peters SG, Hogan WJ, Hashmi SK, Litzow MR, Patnaik MS, Niven AS, Yadav H. Chest. 2021 Jun; 2021 Jan 9. PMID: 33434501.
• Emerging follicular activation strategies to treat women with poor ovarian response and primary ovarian insufficiency.Reig A, Herraiz S, Pellicer A, Seli E. Curr Opin Obstet Gynecol. 2021 Jun 1. PMID: 33896920.
• Endometrial stem cells: origin, biological function, and therapeutic applications for reproductive disorders.Abuwala N, Tal R. Curr Opin Obstet Gynecol. 2021 Jun 1. PMID: 33896919.
• The dynamics of morphogenesis in stem cell-based embryology: Novel insights for symmetry breaking.Sozen B, Cornwall-Scoones J, Zernicka-Goetz M. Dev Biol. 2021 Jun; 2020 Dec 15. PMID: 33333067.
• Altered transcriptome and disease-related phenotype emerge only after fibroblasts harvested from patients with age-related macular degeneration are differentiated into retinal pigment epithelium.Cai H, Gong J, Noggle S, Paull D, Rizzolo LJ, Del Priore LV, Fields MA. Exp Eye Res. 2021 Jun; 2021 Apr 22. PMID: 33895162.
• Defibrotide: potential for treating endothelial dysfunction related to viral and post-infectious syndromes.Richardson E, García-Bernal D, Calabretta E, Jara R, Palomo M, Baron RM, Yanik G, Fareed J, Vlodavsky I, Iacobelli M, Díaz-Ricart M, Richardson PG, Carlo-Stella C, Moraleda JM. Expert Opin Ther Targets. 2021 Jun; 2021 Jun 25. PMID: 34167431.
• Quantification of SV2A Binding in Rodent Brain Using [¹⁸F]SynVesT-1 and PET Imaging.Sadasivam P, Fang XT, Toyonaga T, Lee S, Xu Y, Zheng MQ, Spurrier J, Huang Y, Strittmatter SM, Carson RE, Cai Z. Mol Imaging Biol. 2021 Jun; 2020 Nov 30. PMID: 33258040.
• Bone marrow transplant using fludarabine-based reduced intensity conditioning regimen with in vivo T cell depletion in patients with Fanconi anemia.Gorfinkel L, Demsky C, Pashankar F, Kupfer G, Shah NC. Pediatr Transplant. 2021 Jun; 2021 Mar 23. PMID: 33755277.
• Functional cell death, corneoptosis, requires temporally controlled intracellular acidification.Moore JL, Greco V. Proc Natl Acad Sci U S A. 2021 Jun 1. PMID: 33986147.
• Molecular signaling pathways underlying schizophrenia.Tiihonen J, Koskuvi M, Lähteenvuo M, Trontti K, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Cheng L, Tanskanen A, Taipale H, Lehtonen Š, Koistinaho J. Schizophr Res. 2021 Jun; 2021 May 16. PMID: 34010744.
• Human iPS Cell-derived Tissue Engineered Vascular Graft: Recent Advances and Future Directions.Shi X, He L, Zhang SM, Luo J. Stem Cell Rev Rep. 2021 Jun; 2020 Nov 23. PMID: 33230612.
• Optimization of repeat plerixafor dosing for autologous peripheral blood stem-cell collection.Gupta GK, Perreault S, Seropian SE, Tormey CA, Hendrickson JE. Transfus Apher Sci. 2021 Jun; 2021 Jan 27. PMID: 33546988.
• Infections in activated PI3K delta syndrome (APDS).Brodsky NN, Lucas CL. Curr Opin Immunol. 2021 May 27; 2021 May 27. PMID: 34052541.
• CENTRORADIALIS maintains shoot meristem indeterminacy by antagonizing THORN IDENTITY1 in Citrus.Zhang F, Wang Y, Irish VF. Curr Biol. 2021 May 24; 2021 Mar 23. PMID: 33761317.
• PECUU-ECM Patches: The Future of Ischemic Heart Disease Repair.Ajaj Y, Akingbesote ND, Qyang Y. JACC Basic Transl Sci. 2021 May; 2021 May 24. PMID: 34101774.
• Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras.Samarasinghe KTG, Jaime-Figueroa S, Burgess M, Nalawansha DA, Dai K, Hu Z, Bebenek A, Holley SA, Crews CM. Cell Chem Biol. 2021 May 20; 2021 Apr 8. PMID: 33836141.
• Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons.Gowrishankar S, Lyons L, Rafiq NM, Roczniak-Ferguson A, De Camilli P, Ferguson SM. Mol Biol Cell. 2021 May 15; 2021 Mar 31. PMID: 33788575.
• Single-cell Analysis Technologies for Immuno-oncology Research: from Mechanistic Delineation to Biomarker Discovery.Bai Z, Su G, Fan R. Genomics Proteomics Bioinformatics. 2021 May 14; 2021 May 14. PMID: 34000441.