Recent Publications

2020

Differential Effects of Short-term Environmental Enrichment in Juvenile and Adult Mice.Chandler K, Dosso H, Simard S, Siddiqi S, Rudyk C, Salmaso N. Neuroscience. 2020 Mar 1; 2020 Jan 7. PMID: 31917341.
Higher-risk myelodysplastic syndromes with del(5q): does the del(5q) matter?Gorshein E, Weber UM, Gore S. Expert Rev Hematol. 2020 Feb 18; 2020 Feb 18. PMID: 32067540.
Patents targeting the Warburg effect for cancer therapy: an interview with William P Katt.Katt WP. Pharm Pat Anal. 2020 Feb 14; 2020 Feb 14. PMID: 32057283.
Mammalian ALKBH1 serves as an N⁶-mA demethylase of unpairing DNA.Zhang M, Yang S, Nelakanti R, Zhao W, Liu G, Li Z, Liu X, Wu T, Xiao A, Li H. Cell Res. 2020 Feb 12; 2020 Feb 12. PMID: 32051560.
Synthetic Analyses of Single-Cell Transcriptomes from Multiple Brain Organoids and Fetal Brain.Tanaka Y, Cakir B, Xiang Y, Sullivan GJ, Park IH. Cell Rep. 2020 Feb 11. PMID: 32049002.
Acute Kidney Injury and CKD Associated with Hematopoietic Stem Cell Transplantation.Renaghan AD, Jaimes EA, Malyszko J, Perazella MA, Sprangers B, Rosner MH. Clin J Am Soc Nephrol. 2020 Feb 7; 2019 Dec 13. PMID: 31836598.
Tissue-Engineered Vascular Grafts with Advanced Mechanical Strength from Human iPSCs.Luo J, Qin L, Zhao L, Gui L, Ellis MW, Huang Y, Kural MH, Clark JA, Ono S, Wang J, Yuan Y, Zhang SM, Cong X, Li G, Riaz M, Lopez C, Hotta A, Campbell S, Tellides G, Dardik A, Niklason LE, Qyang Y. Cell Stem Cell. 2020 Feb 6; 2020 Jan 16. PMID: 31956039.
CXCL12 Attracts Bone Marrow-Derived Cells to Uterine Leiomyomas.Moridi I, Mamillapalli R, Kodaman PH, Habata S, Dang T, Taylor HS. Reprod Sci. 2020 Feb 4; 2020 Feb 4. PMID: 32020550.
Incidence and outcomes of rare T cell lymphomas from the T Cell Project: hepatosplenic, enteropathy associated and peripheral gamma delta T cell lymphomas.Foss FM, Horwitz SM, Civallero M, Bellei M, Marcheselli L, Kim WS, Cabrera ME, Dlouhy I, Nagler A, Advani RH, Pesce EA, Ko YH, Montoto S, Chiattone C, Moskowitz A, Spina M, Cesaretti M, Biasoli I, Federico M. Am J Hematol. 2020 Feb; 2019 Nov 25. PMID: 31709579.
Acquired Resistance to HER2-Targeted Therapies Creates Vulnerability to ATP Synthase Inhibition.Gale M, Li Y, Cao J, Liu ZZ, Holmbeck MA, Zhang M, Lang SM, Wu L, Do Carmo M, Gupta S, Aoshima K, DiGiovanna MP, Stern DF, Rimm DL, Shadel GS, Chen X, Yan Q. Cancer Res. 2020 Feb 1; 2019 Nov 5. PMID: 31690671.
Blastula stage specification of avian neural crest.Prasad MS, Uribe-Querol E, Marquez J, Vadasz S, Yardley N, Shelar PB, Charney RM, García-Castro MI. Dev Biol. 2020 Feb 1; 2019 Oct 11. PMID: 31610145.
Parsing the pluripotency continuum in humans and non-human primates for interspecies chimera generation.De Los Angeles A. Exp Cell Res. 2020 Feb 1; 2019 Nov 26. PMID: 31778671.
CXCR4 or CXCR7 antagonists treat endometriosis by reducing bone marrow cell trafficking.Pluchino N, Mamillapalli R, Shaikh S, Habata S, Tal A, Gaye M, Taylor HS. J Cell Mol Med. 2020 Feb; 2020 Jan 6. PMID: 31904910.
Histone lysine demethylase KDM5B maintains chronic myeloid leukemia via multiple epigenetic actions.Xue S, Lam YM, He Z, Zheng Y, Li L, Zhang Y, Li C, Mbadhi MN, Zheng L, Cheng Z, Liu Y, Wang X, Chan LC, Ng RK, Zhang J. Exp Hematol. 2020 Jan 30; 2020 Jan 30. PMID: 32007477.
Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy.Hengel H, Bosso-Lefèvre C, Grady G, Szenker-Ravi E, Li H, Pierce S, Lebigot É, Tan TT, Eio MY, Narayanan G, Utami KH, Yau M, Handal N, Deigendesch W, Keimer R, Marzouqa HM, Gunay-Aygun M, Muriello MJ, Verhelst H, Weckhuysen S, Mahida S, Naidu S, Thomas TG, Lim JY, Tan ES, Haye D, Willemsen MAAP, Oegema R, Mitchell WG, Pierson TM, Andrews MV, Willing MC, Rodan LH, Barakat TS, van Slegtenhorst M, Gavrilova RH, Martinelli D, Gilboa T, Tamim AM, Hashem MO, AlSayed MD, Abdulrahim MM, Al-Owain M, Awaji A, Mahmoud AAH, Faqeih EA, Asmari AA, Algain SM, Jad LA, Aldhalaan HM, Helbig I, Koolen DA, Riess A, Kraegeloh-Mann I, Bauer P, Gulsuner S, Stamberger H, Ng AYJ, Tang S, Tohari S, Keren B, Schultz-Rogers LE, Klee EW, Barresi S, Tartaglia M, Mor-Shaked H, Maddirevula S, Begtrup A, Telegrafi A, Pfundt R, Schüle R, Ciruna B, Bonnard C, Pouladi MA, Stewart JC, Claridge-Chang A, Lefeber DJ, Alkuraya FS, Mathuru AS, Venkatesh B, Barycki JJ, Simpson MA, Jamuar SS, Schöls L, Reversade B. Nat Commun. 2020 Jan 30; 2020 Jan 30. PMID: 32001716.
Publisher Correction: MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors.Chen X, Burkhardt DB, Hartman AA, Hu X, Eastman AE, Sun C, Wang X, Zhong M, Krishnaswamy S, Guo S. Nat Commun. 2020 Jan 29; 2020 Jan 29. PMID: 31996673.
Multiplex CRISPR/Cas screen in regenerating haploid limbs of chimeric Axolotls.Sanor LD, Flowers GP, Crews CM. Elife. 2020 Jan 28; 2020 Jan 28. PMID: 31989926.
Reconstructed Single-Cell Fate Trajectories Define Lineage Plasticity Windows during Differentiation of Human PSC-Derived Distal Lung Progenitors.Hurley K, Ding J, Villacorta-Martin C, Herriges MJ, Jacob A, Vedaie M, Alysandratos KD, Sun YL, Lin C, Werder RB, Huang J, Wilson AA, Mithal A, Mostoslavsky G, Oglesby I, Caballero IS, Guttentag SH, Ahangari F, Kaminski N, Rodriguez-Fraticelli A, Camargo F, Bar-Joseph Z, Kotton DN. Cell Stem Cell. 2020 Jan 27; 2020 Jan 27. PMID: 32004478.
Association of SLC1A1 gene polymorphism with obsessive compulsive disorder in a sample from southern India.Shukla T, Nadella RK, Taj M J RJ, Ganesh S, Nestadt G, Purushottam M, Jain S, Reddy YCJ, Viswanath B. Exp Clin Psychopharmacol. 2020 Jan 27; 2020 Jan 27. PMID: 31985241.
Venetoclax as monotherapy and in combination with hypomethylating agents or low dose cytarabine in relapsed and treatment refractory acute myeloid leukemia: a systematic review and meta-analysis.Bewersdorf JP, Giri S, Wang R, Williams RT, Tallman MS, Zeidan AM, Stahl M. Haematologica. 2020 Jan 23; 2020 Jan 23. PMID: 31974201.
Emerging technologies to study glial cells.Hirbec H, Déglon N, Foo LC, Goshen I, Grutzendler J, Hangen E, Kreisel T, Linck N, Muffat J, Regio S, Rion S, Escartin C. Glia. 2020 Jan 20; 2020 Jan 20. PMID: 31958188.
Microvessel Network Formation and Interactions with Pancreatic Islets in Three-Dimensional Chip Cultures.Rambøl MH, Han E, Niklason LE. Tissue Eng Part A. 2020 Jan 20; 2020 Jan 20. PMID: 31724494.
Comparative Genomic Mapping Implicates LRRK2 for Intellectual Disability and Autism at 12q12, and HDHD1, as Well as PNPLA4, for X-Linked Intellectual Disability at Xp22.31.Labonne JDJ, Driessen TM, Harris ME, Kong IK, Brakta S, Theisen J, Sangare M, Layman LC, Kim CH, Lim J, Kim HG. J Clin Med. 2020 Jan 19; 2020 Jan 19. PMID: 31963867.
Cardiotoxicity in Hematopoietic Stem Cell Transplant: Keeping the Beat.Baker JK, Shank-Coviello J, Zhou B, Dixon J, McCorkle R, Sarpong D, Medoff E, Cooper D, Seropian S, Dai F. Clin Lymphoma Myeloma Leuk. 2020 Jan 18; 2020 Jan 18. PMID: 32067953.
Modular design of a tissue engineered pulsatile conduit using human induced pluripotent stem cell-derived cardiomyocytes.Park J, Anderson CW, Sewanan LR, Kural MH, Huang Y, Luo J, Gui L, Riaz M, Lopez CA, Ng R, Das SK, Wang J, Niklason L, Campbell SG, Qyang Y. Acta Biomater. 2020 Jan 15; 2019 Oct 19. PMID: 31634626.
Author Correction: Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone.Matta R, Lee S, Genet N, Hirschi KK, Thomas JL, Gonzalez AL. Sci Rep. 2020 Jan 14; 2020 Jan 14. PMID: 31932638.
Emerging microbiology diagnostics for transplant infections: On the cusp of a paradigm shift.Azar MM, Gaston DC, Kotton CN, Malinis MF. Transplantation. 2020 Jan 14; 2020 Jan 14. PMID: 31972701.
Humanized mice as preclinical models for myeloid malignancies.Gbyli R, Song Y, Halene S. Biochem Pharmacol. 2020 Jan 10; 2020 Jan 10. PMID: 31926939.
Therapeutic endometrial regeneration: clinical application of bone marrow-derived stem cells.Taylor HS. BJOG. 2020 Jan 10; 2020 Jan 10. PMID: 31925867.
Reply to Cattoretti: Specificity of anti-MYC antibodies.Im I, Son YS, Jung KB, Kang I, Teh BE, Lee KB, Son MY, Kim J. J Biol Chem. 2020 Jan 10. PMID: 31924672.
Incidence, Risk Factors, and Outcomes of Patients Who Develop Mucosal Barrier Injury-Laboratory Confirmed Bloodstream Infections in the First 100 Days After Allogeneic Hematopoietic Stem Cell Transplant.Dandoy CE, Kim S, Chen M, Ahn KW, Ardura MI, Brown V, Chhabra S, Diaz MA, Dvorak C, Farhadfar N, Flagg A, Ganguly S, Hale GA, Hashmi SK, Hematti P, Martino R, Nishihori T, Nusrat R, Olsson RF, Rotz SJ, Sung AD, Perales MA, Lindemans CA, Komanduri KV, Riches ML. JAMA Netw Open. 2020 Jan 3; 2020 Jan 3. PMID: 31913492.
Gene therapy in sickle cell disease: Possible utility and impact.Curtis SA, Shah NC. Cleve Clin J Med. 2020 Jan; 2020 Jan 2. PMID: 31990652.
Author Correction: Visualizing structure and transitions in high-dimensional biological data.Moon KR, van Dijk D, Wang Z, Gigante S, Burkhardt DB, Chen WS, Yim K, van den Elzen A, Hirn MJ, Coifman RR, Ivanova NB, Wolf G, Krishnaswamy S. Nat Biotechnol. 2020 Jan. PMID: 31896828.
Fine-mapping of 150 breast cancer risk regions identifies 191 likely target genes.Fachal L, Aschard H, Beesley J, Barnes DR, Allen J, Kar S, Pooley KA, Dennis J, Michailidou K, Turman C, Soucy P, Lemaçon A, Lush M, Tyrer JP, Ghoussaini M, Moradi Marjaneh M, Jiang X, Agata S, Aittomäki K, Alonso MR, Andrulis IL, Anton-Culver H, Antonenkova NN, Arason A, Arndt V, Aronson KJ, Arun BK, Auber B, Auer PL, Azzollini J, Balmaña J, Barkardottir RB, Barrowdale D, Beeghly-Fadiel A, Benitez J, Bermisheva M, Białkowska K, Blanco AM, Blomqvist C, Blot W, Bogdanova NV, Bojesen SE, Bolla MK, Bonanni B, Borg A, Bosse K, Brauch H, Brenner H, Briceno I, Brock IW, Brooks-Wilson A, Brüning T, Burwinkel B, Buys SS, Cai Q, Caldés T, Caligo MA, Camp NJ, Campbell I, Canzian F, Carroll JS, Carter BD, Castelao JE, Chiquette J, Christiansen H, Chung WK, Claes KBM, Clarke CL, Collée JM, Cornelissen S, Couch FJ, Cox A, Cross SS, Cybulski C, Czene K, Daly MB, de la Hoya M, Devilee P, Diez O, Ding YC, Dite GS, Domchek SM, Dörk T, Dos-Santos-Silva I, Droit A, Dubois S, Dumont M, Duran M, Durcan L, Dwek M, Eccles DM, Engel C, Eriksson M, Evans DG, Fasching PA, Fletcher O, Floris G, Flyger H, Foretova L, Foulkes WD, Friedman E, Fritschi L, Frost D, Gabrielson M, Gago-Dominguez M, Gambino G, Ganz PA, Gapstur SM, Garber J, García-Sáenz JA, Gaudet MM, Georgoulias V, Giles GG, Glendon G, Godwin AK, Goldberg MS, Goldgar DE, González-Neira A, Tibiletti MG, Greene MH, Grip M, Gronwald J, Grundy A, Guénel P, Hahnen E, Haiman CA, Håkansson N, Hall P, Hamann U, Harrington PA, Hartikainen JM, Hartman M, He W, Healey CS, Heemskerk-Gerritsen BAM, Heyworth J, Hillemanns P, Hogervorst FBL, Hollestelle A, Hooning MJ, Hopper JL, Howell A, Huang G, Hulick PJ, Imyanitov EN, Isaacs C, Iwasaki M, Jager A, Jakimovska M, Jakubowska A, James PA, Janavicius R, Jankowitz RC, John EM, Johnson N, Jones ME, Jukkola-Vuorinen A, Jung A, Kaaks R, Kang D, Kapoor PM, Karlan BY, Keeman R, Kerin MJ, Khusnutdinova E, Kiiski JI, Kirk J, Kitahara CM, Ko YD, Konstantopoulou I, Kosma VM, Koutros S, Kubelka-Sabit K, Kwong A, Kyriacou K, Laitman Y, Lambrechts D, Lee E, Leslie G, Lester J, Lesueur F, Lindblom A, Lo WY, Long J, Lophatananon A, Loud JT, Lubiński J, MacInnis RJ, Maishman T, Makalic E, Mannermaa A, Manoochehri M, Manoukian S, Margolin S, Martinez ME, Matsuo K, Maurer T, Mavroudis D, Mayes R, McGuffog L, McLean C, Mebirouk N, Meindl A, Miller A, Miller N, Montagna M, Moreno F, Muir K, Mulligan AM, Muñoz-Garzon VM, Muranen TA, Narod SA, Nassir R, Nathanson KL, Neuhausen SL, Nevanlinna H, Neven P, Nielsen FC, Nikitina-Zake L, Norman A, Offit K, Olah E, Olopade OI, Olsson H, Orr N, Osorio A, Pankratz VS, Papp J, Park SK, Park-Simon TW, Parsons MT, Paul J, Pedersen IS, Peissel B, Peshkin B, Peterlongo P, Peto J, Plaseska-Karanfilska D, Prajzendanc K, Prentice R, Presneau N, Prokofyeva D, Pujana MA, Pylkäs K, Radice P, Ramus SJ, Rantala J, Rau-Murthy R, Rennert G, Risch HA, Robson M, Romero A, Rossing M, Saloustros E, Sánchez-Herrero E, Sandler DP, Santamariña M, Saunders C, Sawyer EJ, Scheuner MT, Schmidt DF, Schmutzler RK, Schneeweiss A, Schoemaker MJ, Schöttker B, Schürmann P, Scott C, Scott RJ, Senter L, Seynaeve CM, Shah M, Sharma P, Shen CY, Shu XO, Singer CF, Slavin TP, Smichkoska S, Southey MC, Spinelli JJ, Spurdle AB, Stone J, Stoppa-Lyonnet D, Sutter C, Swerdlow AJ, Tamimi RM, Tan YY, Tapper WJ, Taylor JA, Teixeira MR, Tengström M, Teo SH, Terry MB, Teulé A, Thomassen M, Thull DL, Tischkowitz M, Toland AE, Tollenaar RAEM, Tomlinson I, Torres D, Torres-Mejía G, Troester MA, Truong T, Tung N, Tzardi M, Ulmer HU, Vachon CM, van Asperen CJ, van der Kolk LE, van Rensburg EJ, Vega A, Viel A, Vijai J, Vogel MJ, Wang Q, Wappenschmidt B, Weinberg CR, Weitzel JN, Wendt C, Wildiers H, Winqvist R, Wolk A, Wu AH, Yannoukakos D, Zhang Y, Zheng W, Hunter D, Pharoah PDP, Chang-Claude J, García-Closas M, Schmidt MK, Milne RL, Kristensen VN, French JD, Edwards SL, Antoniou AC, Chenevix-Trench G, Simard J, Easton DF, Kraft P, Dunning AM. Nat Genet. 2020 Jan; 2020 Jan 7. PMID: 31911677.
MicroRNAs and Regeneration in Animal Models of CNS Disorders.Roitbak T. Neurochem Res. 2020 Jan; 2019 Mar 15. PMID: 30877519.
The critical role of persistent sodium current in hippocampal gamma oscillations.Kang YJ, Clement EM, Sumsky SL, Xiang Y, Park IH, Santaniello S, Greenfield LJ Jr, Garcia-Rill E, Smith BN, Lee SH. Neuropharmacology. 2020 Jan 1; 2019 Sep 21. PMID: 31550457.
Trisomy 21 is Associated with Caspase-2 Upregulation in Cytotrophoblasts at the Maternal-Fetal Interface.Leon-Martinez D, Robinson JF, Zdravkovic T, Genbacev O, Gormley M, Mcmaster M, Fisher SJ, Bianco K. Reprod Sci. 2020 Jan; 2020 Jan 1. PMID: 32046398.
Transfusion Medicine Equations Made Internet Accessible.Hauser RG, Kwon RJ, Ryder A, Cheng C, Charifa A, Tormey C. Transfus Med Rev. 2020 Jan; 2019 Nov 16. PMID: 31785949.
MastocytomaAhmed A, Jan A. 2020 Jan. PMID: 30855840.
Cancer, Lymphoblastic LymphomaKaseb H, Gupta G. 2020 Jan. PMID: 30725922.

2019

Clinical Features and Outcomes of Immunocompromised Children Hospitalized With Laboratory-Confirmed Influenza in the United States, 2011-2015.Collins JP, Campbell AP, Openo K, Farley MM, Cummings CN, Kirley PD, Herlihy R, Yousey-Hindes K, Monroe ML, Ladisky M, Lynfield R, Baumbach J, Spina N, Bennett N, Billing L, Thomas A, Schaffner W, Price A, Garg S, Anderson EJ. J Pediatric Infect Dis Soc. 2019 Dec 27. PMID: 30358877.
The minimal that kills: Why defining and targeting measurable residual disease is the "Sine Qua Non" for further progress in management of acute myeloid leukemia.Bewersdorf JP, Shallis RM, Boddu PC, Wood B, Radich J, Halene S, Zeidan AM. Blood Rev. 2019 Dec 20; 2019 Dec 20. PMID: 31883804.
MLL-AF9 initiates transformation from fast-proliferating myeloid progenitors.Chen X, Burkhardt DB, Hartman AA, Hu X, Eastman AE, Sun C, Wang X, Zhong M, Krishnaswamy S, Guo S. Nat Commun. 2019 Dec 18; 2019 Dec 18. PMID: 31852898.
Cardiac progenitors and paracrine mediators in cardiogenesis and heart regeneration.Witman N, Zhou C, Grote Beverborg N, Sahara M, Chien KR. Semin Cell Dev Biol. 2019 Dec 17; 2019 Dec 17. PMID: 31862220.
Stem cell-derived retinal pigment epithelium from patients with age-related macular degeneration exhibit reduced metabolism and matrix interactions.Gong J, Cai H, Noggle S, Paull D, Rizzolo LJ, Del Priore LV, Fields MA. Stem Cells Transl Med. 2019 Dec 16; 2019 Dec 16. PMID: 31840941.
Application of Human Induced Pluripotent Stem Cells in Generating Tissue-Engineered Blood Vessels as Vascular Grafts.Cong X, Zhang SM, Batty L, Luo J. Stem Cells Dev. 2019 Dec 15; 2019 Nov 26. PMID: 31663439.
Lymphoscintigraphy for Evaluation of Lymphedema Treatment: A Systematic Review.Forte AJ, Boczar D, Huayllani MT, Lu X, Ciudad P. Cureus. 2019 Dec 12; 2019 Dec 12. PMID: 31886094.
Loss of UGP2 in brain leads to a severe epileptic encephalopathy, emphasizing that bi-allelic isoform-specific start-loss mutations of essential genes can cause genetic diseases.Perenthaler E, Nikoncuk A, Yousefi S, Berdowski WM, Alsagob M, Capo I, van der Linde HC, van den Berg P, Jacobs EH, Putar D, Ghazvini M, Aronica E, van IJcken WFJ, de Valk WG, Medici-van den Herik E, van Slegtenhorst M, Brick L, Kozenko M, Kohler JN, Bernstein JA, Monaghan KG, Begtrup A, Torene R, Al Futaisi A, Al Murshedi F, Mani R, Al Azri F, Kamsteeg EJ, Mojarrad M, Eslahi A, Khazaei Z, Darmiyan FM, Doosti M, Karimiani EG, Vandrovcova J, Zafar F, Rana N, Kandaswamy KK, Hertecant J, Bauer P, AlMuhaizea MA, Salih MA, Aldosary M, Almass R, Al-Quait L, Qubbaj W, Coskun S, Alahmadi KO, Hamad MHA, Alwadaee S, Awartani K, Dababo AM, Almohanna F, Colak D, Dehghani M, Mehrjardi MYV, Gunel M, Ercan-Sencicek AG, Passi GR, Cheema HA, Efthymiou S, Houlden H, Bertoli-Avella AM, Brooks AS, Retterer K, Maroofian R, Kaya N, van Ham TJ, Barakat TS. Acta Neuropathol. 2019 Dec 9; 2019 Dec 9. PMID: 31820119.
Mass cytometry-based single-cell analysis of human stem cell reprogramming uncovers differential regulation of specific pluripotency markers.Im I, Son YS, Jung KB, Kang I, Teh BE, Lee KB, Son MY, Kim J. J Biol Chem. 2019 Dec 6; 2019 Sep 30. PMID: 31570522.
Comparative transcriptome analysis of hESC- and iPSC-derived lentoid bodies.Ali M, Kabir F, Thomson JJ, Ma Y, Qiu C, Delannoy M, Khan SY, Riazuddin SA. Sci Rep. 2019 Dec 6; 2019 Dec 6. PMID: 31811247.
Intratumoral delivery of RIG-I agonist SLR14 induces robust antitumor responses.Jiang X, Muthusamy V, Fedorova O, Kong Y, Kim DJ, Bosenberg M, Pyle AM, Iwasaki A. J Exp Med. 2019 Dec 2; 2019 Oct 10. PMID: 31601678.
Targeting Fibrotic Signaling: A Review of Current Literature and Identification of Future Therapeutic Targets to Improve Wound Healing.Hetzler PT 3rd, Dash BC, Guo S, Hsia HC. Ann Plast Surg. 2019 Dec. PMID: 31246672.
Emergent high fatality lung disease in systemic juvenile arthritis.Saper VE, Chen G, Deutsch GH, Guillerman RP, Birgmeier J, Jagadeesh K, Canna S, Schulert G, Deterding R, Xu J, Leung AN, Bouzoubaa L, Abulaban K, Baszis K, Behrens EM, Birmingham J, Casey A, Cidon M, Cron RQ, De A, De Benedetti F, Ferguson I, Fishman MP, Goodman SI, Graham TB, Grom AA, Haines K, Hazen M, Henderson LA, Ho A, Ibarra M, Inman CJ, Jerath R, Khawaja K, Kingsbury DJ, Klein-Gitelman M, Lai K, Lapidus S, Lin C, Lin J, Liptzin DR, Milojevic D, Mombourquette J, Onel K, Ozen S, Perez M, Phillippi K, Prahalad S, Radhakrishna S, Reinhardt A, Riskalla M, Rosenwasser N, Roth J, Schneider R, Schonenberg-Meinema D, Shenoi S, Smith JA, Sönmez HE, Stoll ML, Towe C, Vargas SO, Vehe RK, Young LR, Yang J, Desai T, Balise R, Lu Y, Tian L, Bejerano G, Davis MM, Khatri P, Mellins ED. Ann Rheum Dis. 2019 Dec; 2019 Sep 27. PMID: 31562126.
Suppression of PRPF4 regulates pluripotency, proliferation, and differentiation in mouse embryonic stem cells.Park S, Han SH, Kim HG, Jeong J, Choi M, Kim HY, Kim MG, Park JK, Han JE, Cho GJ, Kim MO, Ryoo ZY, Choi SK. Cell Biochem Funct. 2019 Dec; 2019 Sep 10. PMID: 31502671.
In search of the next super models.Goedel A, Grote Beverborg N, Sahara M, Chien KR. EMBO Mol Med. 2019 Dec; 2019 Nov 18. PMID: 31736275.
CTCF variants in 39 individuals with a variable neurodevelopmental disorder broaden the mutational and clinical spectrum.Konrad EDH, Nardini N, Caliebe A, Nagel I, Young D, Horvath G, Santoro SL, Shuss C, Ziegler A, Bonneau D, Kempers M, Pfundt R, Legius E, Bouman A, Stuurman KE, Õunap K, Pajusalu S, Wojcik MH, Vasileiou G, Le Guyader G, Schnelle HM, Berland S, Zonneveld-Huijssoon E, Kersten S, Gupta A, Blackburn PR, Ellingson MS, Ferber MJ, Dhamija R, Klee EW, McEntagart M, Lichtenbelt KD, Kenney A, Vergano SA, Abou Jamra R, Platzer K, Ella Pierpont M, Khattar D, Hopkin RJ, Martin RJ, Jongmans MCJ, Chang VY, Martinez-Agosto JA, Kuismin O, Kurki MI, Pietiläinen O, Palotie A, Maarup TJ, Johnson DS, Venborg Pedersen K, Laulund LW, Lynch SA, Blyth M, Prescott K, Canham N, Ibitoye R, Brilstra EH, Shinawi M, Fassi E, Sticht H, Gregor A, Van Esch H, Zweier C. Genet Med. 2019 Dec; 2019 Jun 26. PMID: 31239556.
GemC1 is a critical switch for neural stem cell generation in the postnatal brain.Lalioti ME, Kaplani K, Lokka G, Georgomanolis T, Kyrousi C, Dong W, Dunbar A, Parlapani E, Damianidou E, Spassky N, Kahle KT, Papantonis A, Lygerou Z, Taraviras S. Glia. 2019 Dec; 2019 Jul 22. PMID: 31328313.
In Vivo Synaptic Density Imaging with ¹¹C-UCB-J Detects Treatment Effects of Saracatinib in a Mouse Model of Alzheimer Disease.Toyonaga T, Smith LM, Finnema SJ, Gallezot JD, Naganawa M, Bini J, Mulnix T, Cai Z, Ropchan J, Huang Y, Strittmatter SM, Carson RE. J Nucl Med. 2019 Dec; 2019 May 17. PMID: 31101744.
The National MDS Natural History Study: design of an integrated data and sample biorepository to promote research studies in myelodysplastic syndromes.Sekeres MA, Gore SD, Stablein DM, DiFronzo N, Abel GA, DeZern AE, Troy JD, Rollison DE, Thomas JW, Waclawiw MA, Liu JJ, Al Baghdadi T, Walter MJ, Bejar R, Gorak EJ, Starczynowski DT, Foran JM, Cerhan JR, Moscinski LC, Komrokji RS, Deeg HJ, Epling-Burnette PK. Leuk Lymphoma. 2019 Dec; 2019 May 21. PMID: 31111762.
Visualizing structure and transitions in high-dimensional biological data.Moon KR, van Dijk D, Wang Z, Gigante S, Burkhardt DB, Chen WS, Yim K, Elzen AVD, Hirn MJ, Coifman RR, Ivanova NB, Wolf G, Krishnaswamy S. Nat Biotechnol. 2019 Dec; 2019 Dec 3. PMID: 31796933.
Human SNORA31 variations impair cortical neuron-intrinsic immunity to HSV-1 and underlie herpes simplex encephalitis.Lafaille FG, Harschnitz O, Lee YS, Zhang P, Hasek ML, Kerner G, Itan Y, Ewaleifoh O, Rapaport F, Carlile TM, Carter-Timofte ME, Paquet D, Dobbs K, Zimmer B, Gao D, Rojas-Duran MF, Kwart D, Rattina V, Ciancanelli MJ, McAlpine JL, Lorenzo L, Boucherit S, Rozenberg F, Halwani R, Henry B, Amenzoui N, Alsum Z, Marques L, Church JA, Al-Muhsen S, Tardieu M, Bousfiha AA, Paludan SR, Mogensen TH, Quintana-Murci L, Tessier-Lavigne M, Smith GA, Notarangelo LD, Studer L, Gilbert W, Abel L, Casanova JL, Zhang SY. Nat Med. 2019 Dec; 2019 Dec 5. PMID: 31806906.
Uterine Cells Improved Ovarian Function in a Murine Model of Ovarian Insufficiency.Reig A, Mamillapalli R, Coolidge A, Johnson J, Taylor HS. Reprod Sci. 2019 Dec; 2019 Sep 17. PMID: 31530098.
Broad regulation of gene isoform expression by Wnt signaling in cancer.Idris M, Harmston N, Petretto E, Madan B, Virshup DM. RNA. 2019 Dec; 2019 Sep 10. PMID: 31506381.
Optimizing biodegradable nanoparticle size for tissue-specific delivery.Mandl HK, Quijano E, Suh HW, Sparago E, Oeck S, Grun M, Glazer PM, Saltzman WM. J Control Release. 2019 Nov 28; 2019 Oct 22. PMID: 31654688.
Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone.Matta R, Lee S, Genet N, Hirschi KK, Thomas JL, Gonzalez AL. Sci Rep. 2019 Nov 28; 2019 Nov 28. PMID: 31780709.
Modeling the Evolution of Human Brain Development Using Organoids.Muchnik SK, Lorente-Galdos B, Santpere G, Sestan N. Cell. 2019 Nov 27. PMID: 31778651.
LAM-003, a new drug for treatment of tyrosine kinase inhibitor-resistant FLT3-ITD-positive AML.Beeharry N, Landrette S, Gayle S, Hernandez M, Grotzke JE, Young PR, Beckett P, Zhang X, Carter BZ, Andreeff M, Halene S, Xu T, Rothberg J, Lichenstein H. Blood Adv. 2019 Nov 26. PMID: 31751472.
Hsp110 mitigates α-synuclein pathology in vivo.Taguchi YV, Gorenberg EL, Nagy M, Thrasher D, Fenton WA, Volpicelli-Daley L, Horwich AL, Chandra SS. Proc Natl Acad Sci U S A. 2019 Nov 26; 2019 Nov 4. PMID: 31685606.
The Emerging Roles of ATP-Dependent Chromatin Remodeling Complexes in Pancreatic Cancer.Hasan N, Ahuja N. Cancers (Basel). 2019 Nov 25; 2019 Nov 25. PMID: 31769422.
High-throughput continuous dielectrophoretic separation of neural stem cells.Jiang AYL, Yale AR, Aghaamoo M, Lee DH, Lee AP, Adams TNG, Flanagan LA. Biomicrofluidics. 2019 Nov; 2019 Nov 13. PMID: 31737160.
The Firre locus produces a trans-acting RNA molecule that functions in hematopoiesis.Lewandowski JP, Lee JC, Hwang T, Sunwoo H, Goldstein JM, Groff AF, Chang NP, Mallard W, Williams A, Henao-Meija J, Flavell RA, Lee JT, Gerhardinger C, Wagers AJ, Rinn JL. Nat Commun. 2019 Nov 13; 2019 Nov 13. PMID: 31723143.
The golden age for patients in their golden years: The progressive upheaval of age and the treatment of newly-diagnosed acute myeloid leukemia.Shallis RM, Boddu PC, Bewersdorf JP, Zeidan AM. Blood Rev. 2019 Nov 8; 2019 Nov 8. PMID: 31761380.
Interactions of the choroid, Bruch's membrane, retinal pigment epithelium, and neurosensory retina collaborate to form the outer blood-retinal-barrier.Fields MA, Del Priore LV, Adelman RA, Rizzolo LJ. Prog Retin Eye Res. 2019 Nov 5; 2019 Nov 5. PMID: 31704339.
Lifting Each Other Up: Epidermal Stem Cells in Tissue Homeostasis.Horsley V. Dev Cell. 2019 Nov 4. PMID: 31689385.
A novel mouse model demonstrates that oncogenic melanocyte stem cells engender melanoma resembling human disease.Sun Q, Lee W, Mohri Y, Takeo M, Lim CH, Xu X, Myung P, Atit RP, Taketo MM, Moubarak RS, Schober M, Osman I, Gay DL, Saur D, Nishimura EK, Ito M. Nat Commun. 2019 Nov 4; 2019 Nov 4. PMID: 31685822.
Contextualizing the pathology in the essential tremor cerebellar cortex: a patholog-omics approach.Louis ED, Kerridge CA, Chatterjee D, Martuscello RT, Diaz DT, Koeppen AH, Kuo SH, Vonsattel JG, Sims PA, Faust PL. Acta Neuropathol. 2019 Nov; 2019 Jul 17. PMID: 31317229.
A versatile flow-based assay for immunocyte-mediated cytotoxicity.Rabinovich PM, Zhang J, Kerr SR, Cheng BH, Komarovskaya M, Bersenev A, Hurwitz ME, Krause DS, Weissman SM, Katz SG. J Immunol Methods. 2019 Nov; 2019 Sep 13. PMID: 31525367.
In vivo CRISPR screening in CD8 T cells with AAV-Sleeping Beauty hybrid vectors identifies membrane targets for improving immunotherapy for glioblastoma.Ye L, Park JJ, Dong MB, Yang Q, Chow RD, Peng L, Du Y, Guo J, Dai X, Wang G, Errami Y, Chen S. Nat Biotechnol. 2019 Nov; 2019 Sep 23. PMID: 31548728.
Multiplexed activation of endogenous genes by CRISPRa elicits potent antitumor immunity.Wang G, Chow RD, Bai Z, Zhu L, Errami Y, Dai X, Dong MB, Ye L, Zhang X, Renauer PA, Park JJ, Shen L, Ye H, Fuchs CS, Chen S. Nat Immunol. 2019 Nov; 2019 Oct 14. PMID: 31611701.
Engineering of human brain organoids with a functional vascular-like system.Cakir B, Xiang Y, Tanaka Y, Kural MH, Parent M, Kang YJ, Chapeton K, Patterson B, Yuan Y, He CS, Raredon MSB, Dengelegi J, Kim KY, Sun P, Zhong M, Lee S, Patra P, Hyder F, Niklason LE, Lee SH, Yoon YS, Park IH. Nat Methods. 2019 Nov; 2019 Oct 7. PMID: 31591580.
Low iron promotes megakaryocytic commitment of megakaryocytic-erythroid progenitors in humans and mice.Xavier-Ferrucio J, Scanlon V, Li X, Zhang PX, Lozovatsky L, Ayala-Lopez N, Tebaldi T, Halene S, Cao C, Fleming MD, Finberg KE, Krause DS. Blood. 2019 Oct 31. PMID: 31439541.
Adult stem cells and regenerative medicine-a symposium report.Cable J, Fuchs E, Weissman I, Jasper H, Glass D, Rando TA, Blau H, Debnath S, Oliva A, Park S, Passegué E, Kim C, Krasnow MA. Ann N Y Acad Sci. 2019 Oct 26; 2019 Oct 26. PMID: 31655007.
Oxygen sensing and adaptability won the 2019 Nobel Prize in Physiology or medicine.Zhang Q, Yan Q, Yang H, Wei W. Genes Dis. 2019 Dec; 2019 Oct 19. PMID: 31832511.
Uterine stem cells: potential and pitfalls.Tal R, Kisa J. Maturitas. 2019 Oct 19; 2019 Oct 19. PMID: 31668789.
Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression.Merola J, Reschke M, Pierce RW, Qin L, Spindler S, Baltazar T, Manes TD, Lopez-Giraldez F, Li G, Bracaglia LG, Xie C, Kirkiles-Smith N, Saltzman WM, Tietjen GT, Tellides G, Pober JS. JCI Insight. 2019 Oct 17; 2019 Oct 17. PMID: 31527312.
Letter to the editor concerning "Single-institution experience of performing bloodless transplant in Jehovah's Witness patients" by Coltoff A, Aditya S, Solmaz A, and Steinberg A. (Hematol oncol stem cell ther 2019;12(1):44-9.).Zhao JC, Arnall JR, Martin AL, Usmani S, Atrash S. Hematol Oncol Stem Cell Ther. 2019 Oct 11; 2019 Oct 11. PMID: 31628925.
Hair follicle regeneration suppresses Ras-driven oncogenic growth.Pineda CM, Gonzalez DG, Matte-Martone C, Boucher J, Lathrop E, Gallini S, Fons NR, Xin T, Tai K, Marsh E, Nguyen DX, Suozzi KC, Beronja S, Greco V. J Cell Biol. 2019 Oct 7; 2019 Sep 5. PMID: 31488583.
Prevention of neointimal hyperplasia induced by an endovascular stent via intravenous infusion of mesenchymal stem cells.Nakazaki M, Oka S, Sasaki M, Kataoka-Sasaki Y, Onodera R, Komatsu K, Iihoshi S, Hiroura M, Kawaguchi A, Kocsis JD, Honmou O. J Neurosurg. 2019 Oct 4; 2019 Oct 4. PMID: 31585431.
Collisions on the Busy DNA Highway Set Up Barriers for Reprogramming.Hu X, Guo S. Cell Stem Cell. 2019 Oct 3. PMID: 31585090.
Myeloablation followed by autologous stem cell transplantation normalises systemic sclerosis molecular signatures.Assassi S, Wang X, Chen G, Goldmuntz E, Keyes-Elstein L, Ying J, Wallace PK, Turner J, Zheng WJ, Pascual V, Varga J, Hinchcliff ME, Bellocchi C, McSweeney P, Furst DE, Nash RA, Crofford LJ, Welch B, Pinckney A, Mayes MD, Sullivan KM. Ann Rheum Dis. 2019 Oct; 2019 Aug 7. PMID: 31391177.
A Review of Growth Factor Support in Bloodless Autologous Hematopoietic Stem Cell Transplant.Zhao JC, Arnall JR, Martin AL, Atrash S, Bhutani M, Voorhees P, Avalos B, Copelan E, Ghosh N, Hamadani M, Usmani S, Ford P. Biol Blood Marrow Transplant. 2019 Oct; 2019 Jul 8. PMID: 31295572.
Quantitative T2 MRI Mapping and 12-Month Follow-up in a Randomized, Blinded, Placebo Controlled Trial of Bone Marrow Aspiration and Concentration for Osteoarthritis of the Knees.Shapiro SA, Arthurs JR, Heckman MG, Bestic JM, Kazmerchak SE, Diehl NN, Zubair AC, O'Connor MI. Cartilage. 2019 Oct; 2018 Aug 30. PMID: 30160168.
Flexibility sustains epithelial tissue homeostasis.Tai K, Cockburn K, Greco V. Curr Opin Cell Biol. 2019 Oct; 2019 May 29. PMID: 31153058.
Lymph vessels find a hairy niche.Kam CY, Greco V. EMBO J. 2019 Oct 1; 2019 Sep 17. PMID: 31531872.
Cell cycle dynamics in the reprogramming of cellular identity.Hu X, Eastman AE, Guo S. FEBS Lett. 2019 Oct; 2019 Oct 9. PMID: 31562821.
Immunosuppressive therapy for pediatric aplastic anemia: a North American Pediatric Aplastic Anemia Consortium study.Rogers ZR, Nakano TA, Olson TS, Bertuch AA, Wang W, Gillio A, Coates TD, Chawla A, Castillo P, Kurre P, Gamper C, Bennett CM, Joshi S, Geddis AE, Boklan J, Nalepa G, Rothman JA, Huang JN, Kupfer GM, Cada M, Glader B, Walkovich KJ, Thompson AA, Hanna R, Vlachos A, Malsch M, Weller EA, Williams DA, Shimamura A. Haematologica. 2019 Oct; 2019 Apr 4. PMID: 30948484.