Recent Publications

2022

Dyrk1b promotes autophagy during skeletal muscle differentiation by upregulating 4e-bp1.Bhat N, Narayanan A, Fathzadeh M, Shah K, Dianatpour M, Abou Ziki MD, Mani A. Cell Signal. 2022 Feb; 2021 Nov 6. PMID: 34752933.
Single-route CNS prophylaxis for aggressive non-Hodgkin lymphomas: real-world outcomes from 21 US academic institutions.Orellana-Noia VM, Reed DR, McCook AA, Sen JM, Barlow CM, Malecek MK, Watkins M, Kahl BS, Spinner MA, Advani R, Voorhees TJ, Snow A, Grover NS, Ayers A, Romancik J, Liu Y, Huntington SF, Chavez JC, Saeed H, Lazaryan A, Raghunathan V, Spurgeon SE, Ollila TA, Del Prete C, Olszewski A, Ayers EC, Landsburg DJ, Echalier B, Lee J, Kamdar M, Caimi PF, Fu T, Liu J, David KA, Alharthy H, Law J, Karmali R, Shah H, Stephens DM, Major A, Rojek AE, Smith SM, Yellala A, Kallam A, Nakhoda S, Khan N, Sohail MA, Hill BT, Barrett-Campbell O, Lansigan F, Switchenko J, Cohen J, Portell CA. Blood. 2022 Jan 20. PMID: 34570876.
CALGB 40603 (Alliance): Long-Term Outcomes and Genomic Correlates of Response and Survival After Neoadjuvant Chemotherapy With or Without Carboplatin and Bevacizumab in Triple-Negative Breast Cancer.Shepherd JH, Ballman K, Polley MC, Campbell JD, Fan C, Selitsky S, Fernandez-Martinez A, Parker JS, Hoadley KA, Hu Z, Li Y, Soloway MG, Spears PA, Singh B, Tolaney SM, Somlo G, Port ER, Ma C, Kuzma C, Mamounas E, Golshan M, Bellon JR, Collyar D, Hahn OM, Hudis CA, Winer EP, Partridge A, Hyslop T, Carey LA, Perou CM, Sikov WM. J Clin Oncol. 2022 Jan 19; 2022 Jan 19. PMID: 35044810.
Dimethyl Fumarate Reduces Inflammation in Chronic Active Multiple Sclerosis Lesions.Zinger N, Ponath G, Sweeney E, Nguyen TD, Lo CH, Diaz I, Dimov A, Teng L, Zexter L, Comunale J, Wang Y, Pitt D, Gauthier SA. Neurol Neuroimmunol Neuroinflamm. 2022 Mar; 2022 Jan 19. PMID: 35046083.
Cardiomyocytes disrupt pyrimidine biosynthesis in nonmyocytes to regulate heart repair.Li S, Yokota T, Wang P, Ten Hoeve J, Ma F, Le TM, Abt ER, Zhou Y, Wu R, Nanthavongdouangsy M, Rodriguez A, Wang Y, Lin YJ, Muranaka H, Sharpley M, Braddock DT, MacRae VE, Banerjee U, Chiou PY, Seldin M, Huang D, Teitell M, Gertsman I, Jung M, Bensinger SJ, Damoiseaux R, Faull K, Pellegrini M, Lusis AJ, Graeber TG, Radu CG, Deb A. J Clin Invest. 2022 Jan 18. PMID: 34813507.
Installing oncofertility programs for breast cancer in limited versus optimum resource settings: Empirical data from 39 surveyed centers in Repro-Can-OPEN Study Part I & II.Salama M, Lambertini M, Christianson MS, Jayasinghe Y, Anazodo A, De Vos M, Amant F, Stern C, Appiah L, Woodard TL, Anderson RA, Westphal LM, Leach RE, Rodriguez-Wallberg KA, Patrizio P, Woodruff TK. J Assist Reprod Genet. 2022 Jan 15; 2022 Jan 15. PMID: 35032286.
Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing.Martinez NM, Su A, Burns MC, Nussbacher JK, Schaening C, Sathe S, Yeo GW, Gilbert WV. Mol Cell. 2022 Jan 14; 2022 Jan 14. PMID: 35051350.
T cell characteristics associated with toxicity to immune checkpoint blockade in patients with melanoma.Lozano AX, Chaudhuri AA, Nene A, Bacchiocchi A, Earland N, Vesely MD, Usmani A, Turner BE, Steen CB, Luca BA, Badri T, Gulati GS, Vahid MR, Khameneh F, Harris PK, Chen DY, Dhodapkar K, Sznol M, Halaban R, Newman AM. Nat Med. 2022 Jan 13; 2022 Jan 13. PMID: 35027754.
Haploidentical vs sibling, unrelated, or cord blood hematopoietic cell transplantation for acute lymphoblastic leukemia.Wieduwilt MJ, Metheny L, Zhang MJ, Wang HL, Estrada-Merly N, Marks DI, Al-Homsi AS, Muffly L, Chao N, Rizzieri D, Gale RP, Gadalla SM, Cairo M, Mussetti A, Gore S, Bhatt VR, Patel SS, Michelis FV, Inamoto Y, Badawy SM, Copelan E, Palmisiano N, Kharfan-Dabaja MA, Lazarus HM, Ganguly S, Bredeson C, Diaz Perez MA, Cassaday R, Savani BN, Ballen K, Martino R, Wirk B, Bacher U, Aljurf M, Bashey A, Murthy HS, Yared JA, Aldoss I, Farhadfar N, Liu H, Abdel-Azim H, Waller EK, Solh M, Seftel MD, van der Poel M, Grunwald MR, Liesveld JL, Kamble RT, McGuirk J, Munker R, Cahn JY, Lee JW, Freytes CO, Krem MM, Winestone LE, Gergis U, Nathan S, Olsson RF, Verdonck LF, Sharma A, Ringdén O, Friend BD, Cerny J, Choe H, Chhabra S, Nishihori T, Seo S, George B, Baxter-Lowe LA, Hildebrandt GC, de Lima M, Litzow M, Kebriaei P, Hourigan CS, Abid MB, Weisdorf DJ, Saber W. Blood Adv. 2022 Jan 11. PMID: 34547770.
Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern.Li W, Chen Y, Prévost J, Ullah I, Lu M, Gong SY, Tauzin A, Gasser R, Vézina D, Anand SP, Goyette G, Chaterjee D, Ding S, Tolbert WD, Grunst MW, Bo Y, Zhang S, Richard J, Zhou F, Huang RK, Esser L, Zeher A, Côté M, Kumar P, Sodroski J, Xia D, Uchil PD, Pazgier M, Finzi A, Mothes W. Cell Rep. 2022 Jan 11; 2021 Dec 15. PMID: 34971573.
Naive T-Cell Depletion to Prevent Chronic Graft-Versus-Host Disease.Bleakley M, Sehgal A, Seropian S, Biernacki MA, Krakow EF, Dahlberg A, Persinger H, Hilzinger B, Martin PJ, Carpenter PA, Flowers ME, Voutsinas J, Gooley TA, Loeb K, Wood BL, Heimfeld S, Riddell SR, Shlomchik WD. J Clin Oncol. 2022 Jan 10; 2022 Jan 10. PMID: 35007144.
Establishment of an induced pluripotent stem cell line DHMi005-A from a healthy male proband.Dreßen M, Luzius T, Lahm H, Neb I, Doppler SA, Schneider S, Dzilic E, Lange R, Krane M. Stem Cell Res. 2022 Jan 10; 2022 Jan 10. PMID: 35033855.
Evaluation of central line salvage for mucosal barrier injury laboratory-confirmed bloodstream infection (MBI-LCBI) management practices in patients with hematologic malignancies.El Boghdadly Z, Zhao Q, Koutou J, Lustberg ME, Ludwig M, Liscynesky C, Choe H. Leuk Lymphoma. 2022 Jan 8; 2022 Jan 8. PMID: 35001802.
JAGGED1/NOTCH3 activation promotes aortic hypermuscularization and stenosis in elastin deficiency.Dave JM, Chakraborty R, Ntokou A, Saito J, Saddouk FZ, Feng Z, Misra A, Tellides G, Riemer RK, Urban Z, Kinnear C, Ellis J, Mital S, Mecham R, Martin KA, Greif DM. J Clin Invest. 2022 Jan 6; 2022 Jan 6. PMID: 34990407.
Brain ventricles as windows into brain development and disease.Duy PQ, Rakic P, Alper SL, Butler WE, Walsh CA, Sestan N, Geschwind DH, Jin SC, Kahle KT. Neuron. 2022 Jan 5. PMID: 34990576.
Gilteritinib clinical activity in relapsed/refractory FLT3 mutated acute myeloid leukemia previously treated with FLT3 inhibitors.Numan Y, Abdel Rahman Z, Grenet J, Boisclair S, Bewersdorf JP, Collins C, Barth D, Fraga M, Bixby DL, Zeidan AM, Yilmaz M, Desai P, Mannis G, Deutsch YE, Abaza Y, Dinner S, Frankfurt O, Litzow M, Al-Kali A, Foran JM, Sproat LZ, Jovanovic B, Daver N, Perl AE, Altman JK. Am J Hematol. 2022 Jan 3; 2022 Jan 3. PMID: 34981560.
Msl3 promotes germline stem cell differentiation in female Drosophila.McCarthy A, Sarkar K, Martin ET, Upadhyay M, Jang S, Williams ND, Forni PE, Buszczak M, Rangan P. Development. 2022 Jan 1; 2022 Jan 4. PMID: 34878097.
Methods for Differentiating hiPSCs into Vascular Smooth Muscle Cells.Li ML, Luo J, Ellis MW, Riaz M, Ajaj Y, Qyang Y. Methods Mol Biol. 2022. PMID: 34591296.
Establishment of a patient-specific induced pluripotent stem cell line DHMi004-A from a male Holt-Oram syndrome patient with verified TBX5 mutation.Dreßen M, Lahm H, Neb I, Luzius T, Doppler SA, Schneider S, Dzilic E, Lange R, Krane M. Stem Cell Res. 2022 Jan; 2021 Dec 6. PMID: 34894535.

2021

Biallelic PI4KA variants cause neurological, intestinal and immunological disease.Salter CG, Cai Y, Lo B, Helman G, Taylor H, McCartney A, Leslie JS, Accogli A, Zara F, Traverso M, Fasham J, Lees JA, Ferla MP, Chioza BA, Wenger O, Scott E, Cross HE, Crawford J, Warshawsky I, Keisling M, Agamanolis D, Ward Melver C, Cox H, Elawad M, Marton T, Wakeling MN, Holzinger D, Tippelt S, Munteanu M, Valcheva D, Deal C, Van Meerbeke S, Walsh Vockley C, Butte MJ, Acar U, van der Knaap MS, Korenke GC, Kotzaeridou U, Balla T, Simons C, Uhlig HH, Crosby AH, De Camilli P, Wolf NI, Baple EL. Brain. 2021 Dec 31. PMID: 34415310.
Clinical outcomes, Kadish-INSICA staging and therapeutic targeting of somatostatin receptor 2 in olfactory neuroblastoma.Lechner M, Takahashi Y, Turri-Zanoni M, Liu J, Counsell N, Hermsen M, Kaur RP, Zhao T, Ramanathan M Jr, Schartinger VH, Emanuel O, Helman S, Varghese J, Dudas J, Riechelmann H, Sprung S, Haybaeck J, Howard D, Engel NW, Stewart S, Brooks L, Pickles JC, Jacques TS, Fenton TR, Williams L, Vaz FM, O'Flynn P, Stimpson P, Wang S, Hannan SA, Unadkat S, Hughes J, Dwivedi R, Forde CT, Randhawa P, Gane S, Joseph J, Andrews PJ, Royle G, Franchi A, Maragliano R, Battocchio S, Bewicke-Copley H, Pipinikas C, Webster A, Thirlwell C, Ho D, Teschendorff A, Zhu T, Steele CD, Pillay N, Vanhaesebroeck B, Mohyeldin A, Fernandez-Miranda J, Park KW, Le QT, West RB, Saade R, Manes RP, Omay SB, Vining EM, Judson BL, Yarbrough WG, Sansovini M, Silvia N, Grassi I, Bongiovanni A, Capper D, Schüller U, Thavaraj S, Sandison A, Surda P, Hopkins C, Ferrari M, Mattavelli D, Rampinelli V, Facchetti F, Nicolai P, Bossi P, Henriquez OA, Magliocca K, Solares CA, Wise SK, Llorente JL, Patel ZM, Nayak JV, Hwang PH, Lacy PD, Woods R, O'Neill JP, Jay A, Carnell D, Forster MD, Ishii M, London NR Jr, Bell DM, Gallia GL, Castelnuovo P, Severi S, Lund VJ, Hanna EY. Eur J Cancer. 2021 Dec 31; 2021 Dec 31. PMID: 34980502.
Epigallocatechin gallate facilitates extracellular elastin fiber formation in induced pluripotent stem cell derived vascular smooth muscle cells for tissue engineering.Ellis MW, Riaz M, Huang Y, Anderson CW, Luo J, Park J, Lopez CA, Batty LD, Gibson KH, Qyang Y. J Mol Cell Cardiol. 2021 Dec 31; 2021 Dec 31. PMID: 34979103.
CRISPR-Mediated Genomic Addition to CPS1 Deficient iPSCs is Insufficient to Restore Nitrogen Homeostasis.Nitzahn M, Truong B, Khoja S, Vega-Crespo A, Le C, Eliav A, Makris G, Pyle AD, Häberle J, Lipshutz GS. Yale J Biol Med. 2021 Dec; 2021 Dec 29. PMID: 34970092.
Late Endocrine Effects after Stem Cell Transplant in a Young Girl with Griscelli Syndrome.Mencher SR, Tamborlane WV, Patel AD. Case Rep Pediatr. 2021; 2021 Dec 27. PMID: 34987878.
Autologous hematopoietic stem cell product contaminated with Salmonella due to occult salmonellosis in an asymptomatic donor.Jacobs JW, Guarente J, Hendrickson JE, Tormey CA, Bar N. J Clin Apher. 2021 Dec 25; 2021 Dec 25. PMID: 34953078.
Granulocyte Colony-Stimulating Factor is Safe and Well Tolerated following Allogeneic Transplantation in Patients with Sickle Cell Disease.Shah NC, Bhoopatiraju S, Abraham A, Anderson E, Andreansky M, Bhatia M, Chaudhury S, Cuvelier GDE, Godder K, Grimley M, Hale G, Kamani N, Jacobsohn D, Ngwube A, Gilman AL, Skiles J, Yu LC, Shenoy S. Transplant Cell Ther. 2021 Dec 24; 2021 Dec 24. PMID: 34958973.
Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia.Koskuvi M, Lehtonen Š, Trontti K, Keuters M, Wu YC, Koivisto H, Ludwig A, Plotnikova L, Virtanen PLJ, Räsänen N, Kaipainen S, Hyötyläinen I, Dhungana H, Giniatullina R, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Lähteenvuo M, Tohka J, Giniatullin R, Rivera C, Hovatta I, Tanila H, Tiihonen J, Koistinaho J. Glia. 2021 Dec 22; 2021 Dec 22. PMID: 34936134.
Contributions of Na_V1.8 and Na_V1.9 to excitability in human induced pluripotent stem-cell derived somatosensory neurons.Alsaloum M, Labau JIR, Liu S, Estacion M, Zhao P, Dib-Hajj F, Waxman SG. Sci Rep. 2021 Dec 20; 2021 Dec 20. PMID: 34930944.
Human iPSC-Derived Vascular Smooth Muscle Cells in a Fibronectin Functionalized Collagen Hydrogel Augment Endothelial Cell Morphogenesis.Duan K, Dash BC, Sasson DC, Islam S, Parker J, Hsia HC. Bioengineering (Basel). 2021 Dec 18; 2021 Dec 18. PMID: 34940376.
EpoR stimulates rapid cycling and larger red cells during mouse and human erythropoiesis.Hidalgo D, Bejder J, Pop R, Gellatly K, Hwang Y, Maxwell Scalf S, Eastman AE, Chen JJ, Zhu LJ, Heuberger JAAC, Guo S, Koury MJ, Nordsborg NB, Socolovsky M. Nat Commun. 2021 Dec 17; 2021 Dec 17. PMID: 34921133.
Tumor immunology CRISPR screening: present, past, and future.Dong MB, Tang K, Zhou X, Zhou JJ, Chen S. Trends Cancer. 2021 Dec 14; 2021 Dec 14. PMID: 34920978.
Management of hemolytic transfusion reactions.Hendrickson JE, Fasano RM. Hematology Am Soc Hematol Educ Program. 2021 Dec 10. PMID: 34889404.
Evidence-Based Minireview: In young children with severe sickle cell disease, do the benefits of HLA-identical sibling donor HCT outweigh the risks?Shah N, Krishnamurti L. Hematology Am Soc Hematol Educ Program. 2021 Dec 10. PMID: 34889371.
Distinct roles of KLF4 in mesenchymal cell subtypes during lung fibrogenesis.Chandran RR, Xie Y, Gallardo-Vara E, Adams T, Garcia-Milian R, Kabir I, Sheikh AQ, Kaminski N, Martin KA, Herzog EL, Greif DM. Nat Commun. 2021 Dec 10; 2021 Dec 10. PMID: 34893592.
A review of potential novel glaucoma therapeutic options independent of intraocular pressure.Shalaby WS, Ahmed OM, Waisbourd M, Katz LJ. Surv Ophthalmol. 2021 Dec 8; 2021 Dec 8. PMID: 34890600.
Repeated intravenous infusion of mesenchymal stem cells for enhanced functional recovery in a rat model of chronic cerebral ischemia.Takemura M, Sasaki M, Kataoka-Sasaki Y, Kiyose R, Nagahama H, Oka S, Ukai R, Yokoyama T, Kocsis JD, Ueba T, Honmou O. J Neurosurg. 2021 Dec 3; 2021 Dec 3. PMID: 34861644.
Chronic Administration of Thymoquinone Enhances Adult Hippocampal Neurogenesis and Improves Memory in Rats Via Regulating the BDNF Signaling Pathway.Al Mamun A, Matsuzaki K, Islam R, Hossain S, Hossain ME, Katakura M, Arai H, Shido O, Hashimoto M. Neurochem Res. 2021 Dec 2; 2021 Dec 2. PMID: 34855048.
Metabolic decisions in development and disease-a Keystone Symposia report.Cable J, Pourquié O, Wellen KE, Finley LWS, Aulehla A, Gould AP, Teleman A, Tu WB, Garrett WS, Miguel-Aliaga I, Perrimon N, Hooper LV, Walhout AJM, Wei W, Alexandrov T, Erez A, Ralser M, Rabinowitz JD, Hemalatha A, Gutiérrez-Pérez P, Chandel NS, Rutter J, Locasale JW, Landoni JC, Christofk H. Ann N Y Acad Sci. 2021 Dec; 2021 Aug 19. PMID: 34414571.
Clinical definition of acquired resistance to immunotherapy in patients with metastatic non-small-cell lung cancer.Schoenfeld AJ, Antonia SJ, Awad MM, Felip E, Gainor J, Gettinger SN, Hodi FS, Johnson ML, Leighl NB, Lovly CM, Mok T, Perol M, Reck M, Solomon B, Soria JC, Tan DSW, Peters S, Hellmann MD. Ann Oncol. 2021 Dec; 2021 Sep 3. PMID: 34487855.
Adipose-Derived Stem Cells Therapy for Radiation-Induced Skin Injury.Huayllani MT, Ruiz-Garcia H, Boczar D, Avila FR, Lu X, Rinker BD, Moran SL, Sarabia-Estrada R, Quiñones-Hinojosa A, Forte AJ. Ann Plast Surg. 2021 Dec 1. PMID: 34724441.
Identification and validation of a five-lncRNA signature for predicting survival with targeted drug candidates in ovarian cancer.Lin N, Lin JZ, Tanaka Y, Sun P, Zhou X. Bioengineered. 2021 Dec. PMID: 34224310.
Disparities in the long-term survival of adolescent and young adult diffuse large B cell lymphoma survivors.Berkman AM, Andersen CR, Puthenpura V, Livingston JA, Ahmed S, Cuglievan B, Hildebrandt MAT, Roth ME. Cancer Epidemiol. 2021 Dec; 2021 Sep 28. PMID: 34597882.
Integrin αEβ7⁺ T cells direct intestinal stem cell fate decisions via adhesion signaling.Chen S, Zheng Y, Ran X, Du H, Feng H, Yang L, Wen Y, Lin C, Wang S, Huang M, Yan Z, Wu D, Wang H, Ge G, Zeng A, Zeng YA, Chen J. Cell Res. 2021 Dec; 2021 Sep 13. PMID: 34518654.
The Tight Junction Protein ZO-1 Is Dispensable for Barrier Function but Critical for Effective Mucosal Repair.Kuo WT, Zuo L, Odenwald MA, Madha S, Singh G, Gurniak CB, Abraham C, Turner JR. Gastroenterology. 2021 Dec; 2021 Aug 31. PMID: 34478742.
It doesn't always pay to be fit: success landscapes.Phan TV, Wang G, Do TK, Kevrekidis IG, Amend S, Hammarlund E, Pienta K, Brown J, Liu L, Austin RH. J Biol Phys. 2021 Dec; 2021 Oct 28. PMID: 34709534.
Multiview confocal super-resolution microscopy.Wu Y, Han X, Su Y, Glidewell M, Daniels JS, Liu J, Sengupta T, Rey-Suarez I, Fischer R, Patel A, Combs C, Sun J, Wu X, Christensen R, Smith C, Bao L, Sun Y, Duncan LH, Chen J, Pommier Y, Shi YB, Murphy E, Roy S, Upadhyaya A, Colón-Ramos D, La Riviere P, Shroff H. Nature. 2021 Dec; 2021 Nov 26. PMID: 34837071.
Hypomethylating Agents and FLT3 Inhibitors As Maintenance Treatment for Acute Myeloid Leukemia and Myelodysplastic Syndrome After Allogeneic Hematopoietic Stem Cell Transplantation-A Systematic Review and Meta-Analysis.Bewersdorf JP, Allen C, Mirza AS, Grimshaw AA, Giri S, Podoltsev NA, Gowda L, Cho C, Tallman MS, Zeidan AM, Stahl M. Transplant Cell Ther. 2021 Dec; 2021 Sep 20. PMID: 34551341.
Colon cancer cells acquire immune regulatory molecules from tumor-infiltrating lymphocytes by trogocytosis.Shin JH, Jeong J, Maher SE, Lee HW, Lim J, Bothwell ALM. Proc Natl Acad Sci U S A. 2021 Nov 30. PMID: 34819374.
Hexarelin attenuates abdominal aortic aneurysm formation by inhibiting SMC phenotype switch and inflammasome activation.Jiang B, Wang M, Li X, Ren P, Li G, Wang Y, Wang L, Li X, Yang D, Qin L, Xin S. Microvasc Res. 2021 Nov 29; 2021 Nov 29. PMID: 34856183.
Live Birth with or without Preimplantation Genetic Testing for Aneuploidy.Yan J, Qin Y, Zhao H, Sun Y, Gong F, Li R, Sun X, Ling X, Li H, Hao C, Tan J, Yang J, Zhu Y, Liu F, Chen D, Wei D, Lu J, Ni T, Zhou W, Wu K, Gao Y, Shi Y, Lu Y, Zhang T, Wu W, Ma X, Ma H, Fu J, Zhang J, Meng Q, Zhang H, Legro RS, Chen ZJ. N Engl J Med. 2021 Nov 25. PMID: 34818479.
Microglia regulate brain progranulin levels through the endocytosis/lysosomal pathway.Dong T, Tejwani L, Jung Y, Kokubu H, Luttik K, Driessen TM, Lim J. JCI Insight. 2021 Nov 22; 2021 Nov 22. PMID: 34618685.
A Pulmonary Vascular Model From Endothelialized Whole Organ Scaffolds.Yuan Y, Leiby KL, Greaney AM, Raredon MSB, Qian H, Schupp JC, Engler AJ, Baevova P, Adams TS, Kural MH, Wang J, Obata T, Yoder MC, Kaminski N, Niklason LE. Front Bioeng Biotechnol. 2021; 2021 Nov 19. PMID: 34869270.
Transcriptomic taxonomy and neurogenic trajectories of adult human, macaque, and pig hippocampal and entorhinal cells.Franjic D, Skarica M, Ma S, Arellano JI, Tebbenkamp ATN, Choi J, Xu C, Li Q, Morozov YM, Andrijevic D, Vrselja Z, Spajic A, Santpere G, Li M, Zhang S, Liu Y, Spurrier J, Zhang L, Gudelj I, Rapan L, Takahashi H, Huttner A, Fan R, Strittmatter SM, Sousa AMM, Rakic P, Sestan N. Neuron. 2021 Nov 18; 2021 Nov 18. PMID: 34798047.
Metaviromic identification of discriminative genomic features in SARS-CoV-2 using machine learning.Park JJ, Chen S. Patterns (N Y). 2021 Nov 18; 2021 Nov 18. PMID: 34812427.
CRISPR Generated SIX6 and POU4F2 Reporters Allow Identification of Brain and Optic Transcriptional Differences in Human PSC-Derived Organoids.Wahlin KJ, Cheng J, Jurlina SL, Jones MK, Dash NR, Ogata A, Kibria N, Ray S, Eldred KC, Kim C, Heng JS, Phillips J, Johnston RJ Jr, Gamm DM, Berlinicke C, Zack DJ. Front Cell Dev Biol. 2021; 2021 Nov 16. PMID: 34869356.
Possible role of intravenous administration of mesenchymal stem cells to alleviate interstitial cystitis/bladder pain syndrome in a Toll-like receptor-7 agonist-induced experimental animal model in rat.Tabata H, Sasaki M, Kataoka-Sasaki Y, Shinkai N, Ichihara K, Masumori N, Kocsis JD, Honmou O. BMC Urol. 2021 Nov 13; 2021 Nov 13. PMID: 34774029.
Deciphering intratumoral heterogeneity using integrated clonal tracking and single-cell transcriptome analyses.Contreras-Trujillo H, Eerdeng J, Akre S, Jiang D, Contreras J, Gala B, Vergel-Rodriguez MC, Lee Y, Jorapur A, Andreasian A, Harton L, Bramlett CS, Nogalska A, Xiao G, Lee JW, Chan LN, Müschen M, Merchant AA, Lu R. Nat Commun. 2021 Nov 11; 2021 Nov 11. PMID: 34764253.
Connecting copper and cancer: from transition metal signalling to metalloplasia.Ge EJ, Bush AI, Casini A, Cobine PA, Cross JR, DeNicola GM, Dou QP, Franz KJ, Gohil VM, Gupta S, Kaler SG, Lutsenko S, Mittal V, Petris MJ, Polishchuk R, Ralle M, Schilsky ML, Tonks NK, Vahdat LT, Van Aelst L, Xi D, Yuan P, Brady DC, Chang CJ. Nat Rev Cancer. 2021 Nov 11; 2021 Nov 11. PMID: 34764459.
A Machine Learning Model to Successfully Predict Future Diagnosis of Chronic Myelogenous Leukemia With Retrospective Electronic Health Records Data.Hauser RG, Esserman D, Beste LA, Ong SY, Colomb DG, Bhargava A, Wadia R, Rose MG. Am J Clin Pathol. 2021 Nov 8. PMID: 34184028.
Diverse epigenetic mechanisms maintain parental imprints within the embryonic and extraembryonic lineages.Andergassen D, Smith ZD, Kretzmer H, Rinn JL, Meissner A. Dev Cell. 2021 Nov 8. PMID: 34752748.
Giving translation a hand.Strayer EC, Tornini VA, Giraldez AJ. Dev Cell. 2021 Nov 8. PMID: 34752744.
Variants in STXBP3 are Associated with Very Early Onset Inflammatory Bowel Disease, Bilateral Sensorineural Hearing Loss and Immune Dysregulation.Ouahed J, Kelsen JR, Spessott WA, Kooshesh K, Sanmillan ML, Dawany N, Sullivan KE, Hamilton KE, Slowik V, Nejentsev S, Neves JF, Flores H, Chung WK, Wilson A, Anyane-Yeboa K, Wou K, Jain P, Field M, Tollefson S, Dent MH, Li D, Naito T, McGovern DPB, Kwong AC, Taliaferro F, Ordovas-Montanes J, Horwitz BH, Kotlarz D, Klein C, Evans J, Dorsey J, Warner N, Elkadri A, Muise AM, Goldsmith J, Thompson B, Engelhardt KR, Cant AJ, Hambleton S, Barclay A, Toth-Petroczy A, Vuzman D, Carmichael N, Bodea C, Cassa CA, Devoto M, Maas RL, Behrens EM, Giraudo CG, Snapper SB. J Crohns Colitis. 2021 Nov 8. PMID: 33891011.
The potential of platelet-rich plasma injections and stem cell therapy for penile rejuvenation.Israeli JM, Lokeshwar SD, Efimenko IV, Masterson TA, Ramasamy R. Int J Impot Res. 2021 Nov 6; 2021 Nov 6. PMID: 34743193.
How we treat advanced stage cutaneous T-cell lymphoma - mycosis fungoides and Sézary syndrome.Sethi TK, Montanari F, Foss F, Reddy N. Br J Haematol. 2021 Nov; 2021 May 14. PMID: 33987825.
Genomics of human congenital hydrocephalus.Kundishora AJ, Singh AK, Allington G, Duy PQ, Ryou J, Alper SL, Jin SC, Kahle KT. Childs Nerv Syst. 2021 Nov; 2021 Jul 7. PMID: 34232380.
Maintenance therapies in acute myeloid leukemia: the renaissance of an old therapeutic concept.Bewersdorf JP, Tallman MS, Stahl M. Curr Opin Oncol. 2021 Nov 1. PMID: 34341323.
Predictive value of cytoplasmic granulation patterns during in vitro fertilization in metaphase II oocytes: part II, donor oocyte cycles.Hu J, Molinari E, Darmon SK, Zhang L, Patrizio P, Barad DH, Gleicher N. Fertil Steril. 2021 Nov; 2021 Jul 20. PMID: 34294452.
Efficacy and safety of mogamulizumab by patient baseline blood tumour burden: a post hoc analysis of the MAVORIC trial.Cowan RA, Scarisbrick JJ, Zinzani PL, Nicolay JP, Sokol L, Pinter-Brown L, Quaglino P, Iversen L, Dummer R, Musiek A, Foss F, Ito T, Rosen JP, Medley MC. J Eur Acad Dermatol Venereol. 2021 Nov; 2021 Aug 20. PMID: 34273208.
Life Expectancy After Allogeneic Stem Cell Transplant-In It for the Long Haul?Gowda L, Seropian S. JAMA Oncol. 2021 Nov 1. PMID: 34499090.
Lenalidomide, bortezomib and dexamethasone followed by tandem- autologous stem cell transplantation is an effective treatment modality for multi-hit multiple myeloma.Tang S, Lu Y, Zhang P, Chen D, Liu X, Du X, Cao J, Ye P, Chen L, Li S, Sha K, Zhuang XX, Xie Y, Wu X, Pei R. Leuk Res. 2021 Nov; 2021 Sep 21. PMID: 34619433.
Distinction of lymphoid and myeloid clonal hematopoiesis.Niroula A, Sekar A, Murakami MA, Trinder M, Agrawal M, Wong WJ, Bick AG, Uddin MM, Gibson CJ, Griffin GK, Honigberg MC, Zekavat SM, Paruchuri K, Natarajan P, Ebert BL. Nat Med. 2021 Nov; 2021 Oct 18. PMID: 34663986.
Human multipotent adult progenitor cells effectively reduce graft-vs-host disease while preserving graft-vs-leukemia activity.Metheny L, Eid S, Wuttisarnwattana P, Auletta JJ, Liu C, Van Dervort A, Paez C, Lee Z, Wilson D, Lazarus HM, Deans R, Vant Hof W, Ktena Y, Cooke KR. Stem Cells. 2021 Nov; 2021 Jul 28. PMID: 34255899.
Bone marrow-derived progenitor cells contribute to remodeling of the postpartum uterus.Tal R, Kisa J, Abuwala N, Kliman HJ, Shaikh S, Chen AY, Lyu F, Taylor HS. Stem Cells. 2021 Nov; 2021 Aug 6. PMID: 34224633.
Genetic Landscape of Myeloproliferative Neoplasms with an Emphasis on Molecular Diagnostic Laboratory Testing.Easwar A, Siddon AJ. Life (Basel). 2021 Oct 30; 2021 Oct 30. PMID: 34833034.
Sequential Defects in Cardiac Lineage Commitment and Maturation Cause Hypoplastic Left Heart Syndrome.Krane M, Dreßen M, Santamaria G, My I, Schneider CM, Dorn T, Laue S, Mastantuono E, Berutti R, Rawat H, Gilsbach R, Schneider P, Lahm H, Schwarz S, Doppler SA, Paige S, Puluca N, Doll S, Neb I, Brade T, Zhang Z, Abou-Ajram C, Northoff B, Holdt LM, Sudhop S, Sahara M, Goedel A, Dendorfer A, Tjong FVY, Rijlaarsdam ME, Cleuziou J, Lang N, Kupatt C, Bezzina C, Lange R, Bowles NE, Mann M, Gelb BD, Crotti L, Hein L, Meitinger T, Wu S, Sinnecker D, Gruber PJ, Laugwitz KL, Moretti A. Circulation. 2021 Oct 26; 2021 Oct 25. PMID: 34694888.
Retinoic Acid Signaling Modulates Recipient Gut Barrier Integrity and Microbiota After Allogeneic Hematopoietic Stem Cell Transplantation in Mice.Pan P, Atkinson SN, Taylor B, Zhu H, Zhou D, Flejsierowicz P, Wang LS, Morse M, Liu C, Gunsolus IL, Chen X. Front Immunol. 2021; 2021 Oct 25. PMID: 34759928.
Rewiring of human neurodevelopmental gene regulatory programs by human accelerated regions.Girskis KM, Stergachis AB, DeGennaro EM, Doan RN, Qian X, Johnson MB, Wang PP, Sejourne GM, Nagy MA, Pollina EA, Sousa AMM, Shin T, Kenny CJ, Scotellaro JL, Debo BM, Gonzalez DM, Rento LM, Yeh RC, Song JHT, Beaudin M, Fan J, Kharchenko PV, Sestan N, Greenberg ME, Walsh CA. Neuron. 2021 Oct 20; 2021 Sep 2. PMID: 34478631.
A triple-network organization for the mouse brain.Mandino F, Vrooman RM, Foo HE, Yeow LY, Bolton TAW, Salvan P, Teoh CL, Lee CY, Beauchamp A, Luo S, Bi R, Zhang J, Lim GHT, Low N, Sallet J, Gigg J, Lerch JP, Mars RB, Olivo M, Fu Y, Grandjean J. Mol Psychiatry. 2021 Oct 14; 2021 Oct 14. PMID: 34650202.
Choreoathetosis in the Setting of Human Herpesvirus-6 Infection in a Transplant Recipient.Mancone S, Selvadurai C, Baehring J, Patel A. Tremor Other Hyperkinet Mov (N Y). 2021; 2021 Oct 13. PMID: 34721942.
Mastocytosis-A Review of Disease Spectrum with Imaging Correlation.Elsaiey A, Mahmoud HS, Jensen CT, Klimkowski S, Taher A, Chaudhry H, Morani AC, Wong VK, Salem UI, Palmquist SM, Elsayes KM. Cancers (Basel). 2021 Oct 12; 2021 Oct 12. PMID: 34680251.
New concepts for generating interspecies chimeras using human pluripotent stem cells.De Los Angeles A, Wu J. Protein Cell. 2021 Oct 11; 2021 Oct 11. PMID: 34633640.
Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells.Qiu Z, Zhao L, Shen JZ, Liang Z, Wu Q, Yang K, Min L, Gimple RC, Yang Q, Bhargava S, Jin C, Kim C, Hinz D, Dixit D, Bernatchez JA, Prager BC, Zhang G, Dong Z, Lv D, Wang X, Kim LJY, Zhu Z, Jones KA, Zheng Y, Wang X, Siqueira-Neto JL, Chavez L, Fu XD, Spruck C, Rich JN. Cancer Discov. 2021 Oct 6; 2021 Oct 6. PMID: 34615656.
PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation.Li D, Taylor DH, van Wolfswinkel JC. Cell Rep. 2021 Oct 5. PMID: 34610311.
Exploration of alcohol use disorder-associated brain miRNA-mRNA regulatory networks.Lim Y, Beane-Ebel JE, Tanaka Y, Ning B, Husted CR, Henderson DC, Xiang Y, Park IH, Farrer LA, Zhang H. Transl Psychiatry. 2021 Oct 2; 2021 Oct 2. PMID: 34601489.
IRF8 is a Reliable Monoblast Marker for Acute Monocytic Leukemias.Katz SG, Edappallath S, Xu ML. Am J Surg Pathol. 2021 Oct 1. PMID: 34172624.
Infections in activated PI3K delta syndrome (APDS).Brodsky NN, Lucas CL. Curr Opin Immunol. 2021 Oct; 2021 May 27. PMID: 34052541.
Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients.Hashem H, Bucciol G, Ozen S, Unal S, Bozkaya IO, Akarsu N, Taskinen M, Koskenvuo M, Saarela J, Dimitrova D, Hickstein DD, Hsu AP, Holland SM, Krance R, Sasa G, Kumar AR, Müller I, de Sousa MA, Delafontaine S, Moens L, Babor F, Barzaghi F, Cicalese MP, Bredius R, van Montfrans J, Baretta V, Cesaro S, Stepensky P, Benedicte N, Moshous D, Le Guenno G, Boutboul D, Dalal J, Brooks JP, Dokmeci E, Dara J, Lucas CL, Hambleton S, Wilson K, Jolles S, Koc Y, Güngör T, Schnider C, Candotti F, Steinmann S, Schulz A, Chambers C, Hershfield M, Ombrello A, Kanakry JA, Meyts I. J Clin Immunol. 2021 Oct; 2021 Jul 29. PMID: 34324127.
Cost-effectiveness of gilteritinib for relapsed/refractory FLT3^mut+ acute myeloid leukemia.Pandya BJ, Qi CZ, Garnham A, Yang H, Shah MV, Zeidan AM. J Manag Care Spec Pharm. 2021 Oct. PMID: 34595955.
KDM5B promotes immune evasion by recruiting SETDB1 to silence retroelements.Zhang SM, Cai WL, Liu X, Thakral D, Luo J, Chan LH, McGeary MK, Song E, Blenman KRM, Micevic G, Jessel S, Zhang Y, Yin M, Booth CJ, Jilaveanu LB, Damsky W, Sznol M, Kluger HM, Iwasaki A, Bosenberg MW, Yan Q. Nature. 2021 Oct; 2021 Oct 20. PMID: 34671158.
Radial Glial Cells: New Views on Old Questions.Arellano JI, Morozov YM, Micali N, Rakic P. Neurochem Res. 2021 Oct; 2021 Mar 16. PMID: 33725233.
Intravenous Infusion of Mesenchymal Stem Cells Promotes the Survival of Random Pattern Flaps in Rats.Nakagawa T, Sasaki M, Kataoka-Sasaki Y, Yotsuyanagi T, Radtke C, Kocsis JD, Honmou O. Plast Reconstr Surg. 2021 Oct 1. PMID: 34550936.
tRNA-like leader-trailer interaction promotes 3'-end maturation of MALAT1.Torabi SF, DeGregorio SJ, Steitz JA. RNA. 2021 Oct; 2021 Jul 12. PMID: 34253686.
A reservoir of stem-like CD8⁺ T cells in the tumor-draining lymph node preserves the ongoing antitumor immune response.Connolly KA, Kuchroo M, Venkat A, Khatun A, Wang J, William I, Hornick NI, Fitzgerald BL, Damo M, Kasmani MY, Cui C, Fagerberg E, Monroy I, Hutchins A, Cheung JF, Foster GG, Mariuzza DL, Nader M, Zhao H, Cui W, Krishnaswamy S, Joshi NS. Sci Immunol. 2021 Oct; 2021 Sep 2. PMID: 34597124.
CTCFL expression is associated with cerebral vascular abnormalities.Sati L, Soygur B, Goksu E, Bassorgun CI, McGrath J. Tissue Cell. 2021 Oct; 2021 Mar 16. PMID: 33756271.
Outcomes of Allogeneic Hematopoietic Cell Transplantation in Patients With Myelofibrosis-A Systematic Review and Meta-Analysis.Bewersdorf JP, Sheth AH, Vetsa S, Grimshaw A, Giri S, Podoltsev NA, Gowda L, Tamari R, Tallman MS, Rampal RK, Zeidan AM, Stahl M. Transplant Cell Ther. 2021 Oct; 2021 May 28. PMID: 34052505.
A Human Pleiotropic Multiorgan Condition Caused by Deficient Wnt Secretion.Chai G, Szenker-Ravi E, Chung C, Li Z, Wang L, Khatoo M, Marshall T, Jiang N, Yang X, McEvoy-Venneri J, Stanley V, Anzenberg P, Lang N, Wazny V, Yu J, Virshup DM, Nygaard R, Mancia F, Merdzanic R, Toralles MBP, Pitanga PML, Puri RD, Hernan R, Chung WK, Bertoli-Avella AM, Al-Sannaa N, Zaki MS, Willert K, Reversade B, Gleeson JG. N Engl J Med. 2021 Sep 30. PMID: 34587386.
Human embryo polarization requires PLC signaling to mediate trophectoderm specification.Zhu M, Shahbazi M, Martin A, Zhang C, Sozen B, Borsos M, Mandelbaum RS, Paulson RJ, Mole MA, Esbert M, Titus S, Scott RT, Campbell A, Fishel S, Gradinaru V, Zhao H, Wu K, Chen ZJ, Seli E, de Los Santos MJ, Zernicka Goetz M. Elife. 2021 Sep 27; 2021 Sep 27. PMID: 34569938.
Reconstructing aspects of human embryogenesis with pluripotent stem cells.Sozen B, Jorgensen V, Weatherbee BAT, Chen S, Zhu M, Zernicka-Goetz M. Nat Commun. 2021 Sep 21; 2021 Sep 21. PMID: 34548496.
The roles of epigenetics in cancer progression and metastasis.Chen JF, Yan Q. Biochem J. 2021 Sep 17. PMID: 34520519.
Emergence of an early SARS-CoV-2 epidemic in the United States.Zeller M, Gangavarapu K, Anderson C, Smither AR, Vanchiere JA, Rose R, Snyder DJ, Dudas G, Watts A, Matteson NL, Robles-Sikisaka R, Marshall M, Feehan AK, Sabino-Santos G Jr, Bell-Kareem AR, Hughes LD, Alkuzweny M, Snarski P, Garcia-Diaz J, Scott RS, Melnik LI, Klitting R, McGraw M, Belda-Ferre P, DeHoff P, Sathe S, Marotz C, Grubaugh ND, Nolan DJ, Drouin AC, Genemaras KJ, Chao K, Topol S, Spencer E, Nicholson L, Aigner S, Yeo GW, Farnaes L, Hobbs CA, Laurent LC, Knight R, Hodcroft EB, Khan K, Fusco DN, Cooper VS, Lemey P, Gardner L, Lamers SL, Kamil JP, Garry RF, Suchard MA, Andersen KG. Cell. 2021 Sep 16; 2021 Jul 27. PMID: 34508652.