Recent Publications

2022

• Outcomes of TP53-mutated AML with evolving frontline therapies: Impact of allogeneic stem cell transplantation on survival.Badar T, Atallah E, Shallis RM, Goldberg AD, Patel A, Abaza Y, Bewersdorf JP, Saliba AN, Correia GSC, Murthy G, Duvall A, Burkart M, Stahl M, Liu Y, Dinner S, Palmisiano N, Litzow MR, Foran JM. Am J Hematol. 2022 Jul; 2022 Mar 30. PMID: 35338673.
• International guidelines regarding the role of IVIG in the management of Rh- and ABO-mediated haemolytic disease of the newborn.Lieberman L, Lopriore E, Baker JM, Bercovitz RS, Christensen RD, Crighton G, Delaney M, Goel R, Hendrickson JE, Keir A, Landry D, La Rocca U, Lemyre B, Maier RF, Muniz-Diaz E, Nahirniak S, New HV, Pavenski K, Dos Santos MCP, Ramsey G, Shehata N. Br J Haematol. 2022 Jul; 2022 Apr 12. PMID: 35415922.
• When should we tell patients there may be no blood? Evaluating the 'informed' consent process.Booth GS, Jacobs JW, Stephens LD, Chooljian DM, Savani BN, Gehrie EA. Br J Haematol. 2022 Jul; 2022 Mar 22. PMID: 35315509.
• Downregulation of SATB1 by miRNAs reduces megakaryocyte/erythroid progenitor expansion in preclinical models of Diamond-Blackfan anemia.Wilkes MC, Scanlon V, Shibuya A, Cepika AM, Eskin A, Chen Z, Narla A, Glader B, Roncarolo MG, Nelson SF, Sakamoto KM. Exp Hematol. 2022 Jul; 2022 Apr 20. PMID: 35460833.
• Live isolation of naïve ESCs via distinct glucose metabolism and stored glycogen.Kim KT, Oh JY, Park S, Kim SM, Benjamin P, Park IH, Chun KH, Chang YT, Cha HJ. Metab Eng. 2022 Jul; 2022 Mar 10. PMID: 35283260.
• A review of potential novel glaucoma therapeutic options independent of intraocular pressure.Shalaby WS, Ahmed OM, Waisbourd M, Katz LJ. Surv Ophthalmol. 2022 Jul-Aug; 2021 Dec 8. PMID: 34890600.
• Coupled fibromodulin and SOX2 signaling as a critical regulator of metastatic outgrowth in melanoma.Oria VO, Zhang H, Zito CR, Rane CK, Ma XY, Provance OK, Tran TT, Adeniran A, Kluger Y, Sznol M, Bosenberg MW, Kluger HM, Jilaveanu LB. Cell Mol Life Sci. 2022 Jun 23; 2022 Jun 23. PMID: 35737114.
• Toxic epidermal necrolysis-like acute graft-versus-host disease in pediatric bone marrow transplant patients: Case series and review of the literature.Sheu Song J, Huang JT, Fraile Alonso MDC, Antaya RJ, Price HN, Funk T, Francois RA, Shah SD. Pediatr Dermatol. 2022 Jun 21; 2022 Jun 21. PMID: 35730149.
• Unmixing for ultra-high-plex fluorescence imaging.Enninful A, Baysoy A, Fan R. Nat Commun. 2022 Jun 16; 2022 Jun 16. PMID: 35710800.
• A p300/GATA6 axis determines differentiation and Wnt dependency in pancreatic cancer models.Zhong Z, Harmston N, Wood KC, Madan B, Virshup DM. J Clin Invest. 2022 Jun 15. PMID: 35536676.
• Microglial amyloid beta clearance is driven by PIEZO1 channels.Jäntti H, Sitnikova V, Ishchenko Y, Shakirzyanova A, Giudice L, Ugidos IF, Gómez-Budia M, Korvenlaita N, Ohtonen S, Belaya I, Fazaludeen F, Mikhailov N, Gotkiewicz M, Ketola K, Lehtonen Š, Koistinaho J, Kanninen KM, Hernández D, Pébay A, Giugno R, Korhonen P, Giniatullin R, Malm T. J Neuroinflammation. 2022 Jun 15; 2022 Jun 15. PMID: 35706029.
• Chemokine C-X-C receptor 4 mediates recruitment of bone marrow-derived nonhematopoietic and immune cells to the pregnant uterus†.Fang YY, Lyu F, Abuwala N, Tal A, Chen AY, Taylor HS, Tal R. Biol Reprod. 2022 Jun 13. PMID: 35134114.
• Carnegie in 4D? Stem-cell-based models of human embryo development.Sozen B, Conkar D, Veenvliet JV. Semin Cell Dev Biol. 2022 Jun 11; 2022 Jun 11. PMID: 35701286.
• Bioinformatics identifies predictors of arteriovenous fistula maturation.Liu J, Zhang D, Brahmandam A, Matsubara Y, Gao M, Tian J, Liu B, Shu C, Dardik A. J Vasc Access. 2022 Jun 10; 2022 Jun 10. PMID: 35686495.
• Single-cell antigen-specific landscape of CAR T infusion product identifies determinants of CD19-positive relapse in patients with ALL.Bai Z, Woodhouse S, Zhao Z, Arya R, Govek K, Kim D, Lundh S, Baysoy A, Sun H, Deng Y, Xiao Y, Barrett DM, Myers RM, Grupp SA, June CH, Fan R, Camara PG, Melenhorst JJ. Sci Adv. 2022 Jun 10; 2022 Jun 8. PMID: 35675405.
• Extramedullary hematopoietic stem cells.Gallagher PG. Blood. 2022 Jun 9. PMID: 35679074.
• Follow-up of patients with R/R FLT3-mutation-positive AML treated with gilteritinib in the phase 3 ADMIRAL trial.Perl AE, Larson RA, Podoltsev NA, Strickland S, Wang ES, Atallah E, Schiller GJ, Martinelli G, Neubauer A, Sierra J, Montesinos P, Récher C, Yoon SS, Hosono N, Onozawa M, Chiba S, Kim HJ, Hasabou N, Lu Q, Tiu R, Levis MJ. Blood. 2022 Jun 9. PMID: 35081255.
• Rare pathogenic variants in WNK3 cause X-linked intellectual disability.Küry S, Zhang J, Besnard T, Caro-Llopis A, Zeng X, Robert SM, Josiah SS, Kiziltug E, Denommé-Pichon AS, Cogné B, Kundishora AJ, Hao LT, Li H, Stevenson RE, Louie RJ, Deb W, Torti E, Vignard V, McWalter K, Raymond FL, Rajabi F, Ranza E, Grozeva D, Coury SA, Blanc X, Brischoux-Boucher E, Keren B, Õunap K, Reinson K, Ilves P, Wentzensen IM, Barr EE, Guihard SH, Charles P, Seaby EG, Monaghan KG, Rio M, van Bever Y, van Slegtenhorst M, Chung WK, Wilson A, Quinquis D, Bréhéret F, Retterer K, Lindenbaum P, Scalais E, Rhodes L, Stouffs K, Pereira EM, Berger SM, Milla SS, Jaykumar AB, Cobb MH, Panchagnula S, Duy PQ, Vincent M, Mercier S, Gilbert-Dussardier B, Le Guillou X, Audebert-Bellanger S, Odent S, Schmitt S, Boisseau P, Bonneau D, Toutain A, Colin E, Pasquier L, Redon R, Bouman A, Rosenfeld JA, Friez MJ, Pérez-Peña H, Akhtar Rizvi SR, Haider S, Antonarakis SE, Schwartz CE, Martínez F, Bézieau S, Kahle KT, Isidor B. Genet Med. 2022 Jun 9; 2022 Jun 9. PMID: 35678782.
• Regenerative Approaches for Chronic Wounds.Berthiaume F, Hsia HC. Annu Rev Biomed Eng. 2022 Jun 6; 2022 Feb 28. PMID: 35226819.
• A group approach to growing as a principal investigator.Greco V, Politi K, Eisenbarth S, Colón-Ramos D, Giraldez AJ, Bewersdorf J, Berg DN. Curr Biol. 2022 Jun 6. PMID: 35671717.
• Omicron-specific mRNA vaccination alone and as a heterologous booster against SARS-CoV-2.Fang Z, Peng L, Filler R, Suzuki K, McNamara A, Lin Q, Renauer PA, Yang L, Menasche B, Sanchez A, Ren P, Xiong Q, Strine M, Clark P, Lin C, Ko AI, Grubaugh ND, Wilen CB, Chen S. Nat Commun. 2022 Jun 6; 2022 Jun 6. PMID: 35668119.
• The seventh international RASopathies symposium: Pathways to a cure-expanding knowledge, enhancing research, and therapeutic discovery.Kontaridis MI, Roberts AE, Schill L, Schoyer L, Stronach B, Andelfinger G, Aoki Y, Axelrad ME, Bakker A, Bennett AM, Broniscer A, Castel P, Chang CA, Cyganek L, Das TK, den Hertog J, Galperin E, Garg S, Gelb BD, Gordon K, Green T, Gripp KW, Itkin M, Kiuru M, Korf BR, Livingstone JR, López-Juárez A, Magoulas PL, Mansour S, Milner T, Parker E, Pierpont EI, Plouffe K, Rauen KA, Shankar SP, Smith SB, Stevenson DA, Tartaglia M, Van R, Wagner ME, Ware SM, Zenker M. Am J Med Genet A. 2022 Jun; 2022 Mar 9. PMID: 35266292.
• Analysis of the genomic landscapes of Barbadian and Nigerian women with triple negative breast cancer.Hercules SM, Liu X, Bassey-Archibong BBI, Skeete DHA, Smith Connell S, Daramola A, Banjo AA, Ebughe G, Agan T, Ekanem IO, Udosen J, Obiorah C, Ojule AC, Misauno MA, Dauda AM, Egbujo EC, Hercules JC, Ansari A, Brain I, MacColl C, Xu Y, Jin Y, Chang S, Carpten JD, Bédard A, Pond GR, Blenman KRM, Manojlovic Z, Daniel JM. Cancer Causes Control. 2022 Jun; 2022 Apr 6. PMID: 35384527.
• Long-term neurocognitive and quality of life outcomes in survivors of pediatric hematopoietic cell transplant.Wu NL, Krull KR, Cushing-Haugen KL, Ullrich NJ, Kadan-Lottick NS, Lee SJ, Chow EJ. J Cancer Surviv. 2022 Jun; 2021 Jun 4. PMID: 34086185.
• Autologous hematopoietic stem cell product contaminated with Salmonella due to occult salmonellosis in an asymptomatic donor.Jacobs JW, Guarente J, Hendrickson JE, Tormey CA, Bar N. J Clin Apher. 2022 Jun; 2021 Dec 25. PMID: 34953078.
• Evaluation of central line salvage for mucosal barrier injury laboratory-confirmed bloodstream infection (MBI-LCBI) management practices in patients with hematologic malignancies.El Boghdadly Z, Zhao Q, Koutou J, Lustberg ME, Ludwig M, Liscynesky C, Choe H. Leuk Lymphoma. 2022 Jun; 2022 Jan 8. PMID: 35001802.
• Author Correction: Targeted tumour theranostics in mice via carbon quantum dots structurally mimicking large amino acids.Li S, Su W, Wu H, Yuan T, Yuan C, Liu J, Deng G, Gao X, Chen Z, Bao Y, Yuan F, Zhou S, Tan H, Li Y, Li X, Fan L, Zhu J, Chen AT, Liu F, Zhou Y, Li M, Zhai X, Zhou J. Nat Biomed Eng. 2022 Jun. PMID: 35064254.
• Pathogen-induced hydraulic decline limits photosynthesis and starch storage in grapevines (Vitis sp.).Fanton AC, Furze ME, Brodersen CR. Plant Cell Environ. 2022 Jun; 2022 Mar 28. PMID: 35297057.
• Hematopoietic Cell Transplantation for Congenital Dyserythropoietic Anemia: A Report from the Pediatric Transplant and Cellular Therapy Consortium.Rangarajan HG, Stanek JR, Abdel-Azim H, Modi A, Haight A, McKinney CM, McKeone DJ, Buchbinder DK, Katsanis E, Abusin GA, Ahmed I, Law J, Silva JG, Mallhi KK, Burroughs LM, Shah N, Shaw PJ, Greiner R, Shenoy S, Pulsipher MA, Abu-Arja R. Transplant Cell Ther. 2022 Jun; 2022 Mar 11. PMID: 35288346.
• Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation.Ding P, Tan Q, Wei Z, Chen Q, Wang C, Qi L, Wen L, Zhang C, Yao C. Bone Res. 2022 May 27; 2022 May 27. PMID: 35624094.
• The transition phase: preparing to launch a laboratory.McKinley KL, Didychuk AL, Nicholas DA, Termini CM. Trends Biochem Sci. 2022 May 26; 2022 May 26. PMID: 35644775.
• Enhanced network in corticospinal tracts after infused mesenchymal stem cells in spinal cord injury.Hirota R, Sasaki M, Kataoka-Sasaki Y, Oshigiri T, Kurihara K, Fukushi R, Oka S, Ukai R, Yoshimoto M, Kocsis JD Ph.D, Yamashita T, Honmou O. J Neurotrauma. 2022 May 25; 2022 May 25. PMID: 35611987.
• Molecular Oncology of Bladder Cancer from Inception to Modern Perspective.Lokeshwar SD, Lopez M, Sarcan S, Aguilar K, Morera DS, Shaheen DM, Lokeshwar BL, Lokeshwar VB. Cancers (Basel). 2022 May 24; 2022 May 24. PMID: 35681556.
• Donor T-cell DNMT3a regulates alloreactivity in murine models of hematopoietic stem cell transplantation.Ktena YP, Koldobskiy MA, Barbato MI, Fu HH, Luznik L, Llosa NJ, Haile A, Klein OR, Liu C, Gamper CJ, Cooke KR. J Clin Invest. 2022 May 24; 2022 May 24. PMID: 35608905.
• Transcriptome-wide mapping reveals a diverse dihydrouridine landscape including mRNA.Draycott AS, Schaening-Burgos C, Rojas-Duran MF, Wilson L, Schärfen L, Neugebauer KM, Nachtergaele S, Gilbert WV. PLoS Biol. 2022 May; 2022 May 24. PMID: 35609439.
• Melatonin in ventricular and subarachnoid cerebrospinal fluid: Its function in the neural glymphatic network and biological significance for neurocognitive health.Reiter RJ, Sharma R, Rosales-Corral S, de Mange J, Phillips WT, Tan DX, Bitar RD. Biochem Biophys Res Commun. 2022 May 21; 2022 Mar 17. PMID: 35316766.
• Single-Cell Transcriptomics Revealed Subtype-Specific Tumor Immune Microenvironments in Human Glioblastomas.Xiao Y, Wang Z, Zhao M, Deng Y, Yang M, Su G, Yang K, Qian C, Hu X, Liu Y, Geng L, Xiao Y, Zou Y, Tang X, Liu H, Xiao H, Fan R. Front Immunol. 2022; 2022 May 20. PMID: 35669791.
• Pyruvate kinase M1 suppresses development and progression of prostate adenocarcinoma.Davdison SM, Schmidt DR, Heyman JE, O'Brien JP, Liu AC, Israelsen WJ, Dayton TL, Sehgal R, Bronson RT, Freinkman E, Mak HH, Fanelli GN, Malstrom S, Bellinger G, Carracedo A, Pandolfi PP, Courtney KD, Jha A, DePinho RA, Horner JW, Thomas CJ, Cantley LC, Loda M, Vander Heiden MG. Cancer Res. 2022 May 18; 2022 May 18. PMID: 35584006.
• Variant-specific vaccination induces systems immune responses and potent in vivo protection against SARS-CoV-2.Peng L, Renauer PA, Ökten A, Fang Z, Park JJ, Zhou X, Lin Q, Dong MB, Filler R, Xiong Q, Clark P, Lin C, Wilen CB, Chen S. Cell Rep Med. 2022 May 17; 2022 Apr 26. PMID: 35561673.
• Relationship of Oropharyngeal Colonization Microorganisms to Clinical Outcomes within 100 Days after Allogeneic Hematopoietic Stem Cell Transplantation.Ge J, Wei X, Gu Y, Xie Y, Li H, Zhou S, Liu C, Li S, Wu W, Xu J, Ma X, Tang Z, He J, Wu D, Wu X, Liu J. Transplant Cell Ther. 2022 May 16; 2022 May 16. PMID: 35589057.
• Are We Moving the Needle for Patients with TP53-Mutated Acute Myeloid Leukemia?Shallis RM, Bewersdorf JP, Stahl MF, Halene S, Zeidan AM. Cancers (Basel). 2022 May 14; 2022 May 14. PMID: 35626039.
• Pan-Cancer Single-Cell Analysis Reveals the Core Factors and Pathway in Specific Cancer Stem Cells of Upper Gastrointestinal Cancer.Li L, Zhang Y, Ren Y, Cheng Z, Zhang Y, Wang X, Zhao H, Lu H. Front Bioeng Biotechnol. 2022; 2022 May 13. PMID: 35646860.
• Genome editing in animals with minimal PAM CRISPR-Cas9 enzymes.Vicencio J, Sánchez-Bolaños C, Moreno-Sánchez I, Brena D, Vejnar CE, Kukhtar D, Ruiz-López M, Cots-Ponjoan M, Rubio A, Melero NR, Crespo-Cuadrado J, Carolis C, Pérez-Pulido AJ, Giráldez AJ, Kleinstiver BP, Cerón J, Moreno-Mateos MA. Nat Commun. 2022 May 12; 2022 May 12. PMID: 35552388.
• Author Correction: Integrative molecular and clinical profiling of acral melanoma links focal amplification of 22q11.21 to metastasis.Farshidfar F, Rhrissorrakrai K, Levovitz C, Peng C, Knight J, Bacchiocchi A, Su J, Yin M, Sznol M, Ariyan S, Clune J, Olino K, Parida L, Nikolaus J, Zhang M, Zhao S, Wang Y, Huang G, Wan M, Li X, Cao J, Yan Q, Chen X, Newman AM, Halaban R. Nat Commun. 2022 May 10; 2022 May 10. PMID: 35538087.
• A non-canonical Raf function is required for dorsal-ventral patterning during Drosophila embryogenesis.Lusk JB, Chua EHZ, Kaur P, Sung ICH, Lim WK, Lam VYM, Harmston N, Tolwinski NS. Sci Rep. 2022 May 10; 2022 May 10. PMID: 35538124.
• Prepubertal androgen signaling is required to establish male fat distribution.Sebo ZL, Rodeheffer MS. Stem Cell Reports. 2022 May 10; 2022 Apr 28. PMID: 35487210.
• Pre-transplant infusion of donor leukocytes treated with extracorporeal photochemotherapy induces immune hypo-responsiveness and long-term allograft survival in murine models.Schneiderman J, Qiu L, Yeap XY, Kang X, Zheng F, Ye J, Xie Y, Wang JJ, Sambandam Y, Mathew J, Li L, Leventhal J, Edelson RL, Zhang ZJ. Sci Rep. 2022 May 4; 2022 May 4. PMID: 35508582.
• The steroid hormone estriol (E₃) regulates epigenetic programming of fetal mouse brain and reproductive tract.Zhou Y, Gu B, Brichant G, Singh JP, Yang H, Chang H, Zhao Y, Cheng C, Liu ZW, Alderman MH 3rd, Lu L, Yang X, Gao XB, Taylor HS. BMC Biol. 2022 May 2; 2022 May 2. PMID: 35491423.
• Integrative genome-wide analysis reveals EIF3A as a key downstream regulator of translational repressor protein Musashi 2 (MSI2).Karmakar S, Ramirez O, Paul KV, Gupta AK, Kumari V, Botti V, de Los Mozos IR, Neuenkirchen N, Ross RJ, Karanicolas J, Neugebauer KM, Pillai MM. NAR Cancer. 2022 Jun; 2022 May 2. PMID: 35528200.
• Development of patient derived organoids for cancer drug screening applications.Baskar G, Palaniyandi T, Viswanathan S, Rajendran BK, Ravi M, Sivaji A. Acta Histochem. 2022 May; 2022 Apr 26. PMID: 35486967.
• Using Stem Cell Models to Explore the Genetics Underlying Psychiatric Disorders: Linking Risk Variants, Genes, and Biology in Brain Disease.Brennand KJ. Am J Psychiatry. 2022 May. PMID: 35491564.
• Human Amniotic Membrane as a Novel Scaffold for Inducible Pluripotent Stem Cell-derived Kidney Organoids.Figetakis M, James KJ, Kosyakova N, Torres R, Chang WG. ASAIO J. 2022 May 1; 2021 May 6. PMID: 35503644.
• Recruitment of monocytes primed to express heme oxygenase-1 ameliorates pathological lung inflammation in cystic fibrosis.Di Pietro C, Öz HH, Zhang PX, Cheng EC, Martis V, Bonfield TL, Kelley TJ, Jubin R, Abuchowski A, Krause DS, Egan ME, Murray TS, Bruscia EM. Exp Mol Med. 2022 May; 2022 May 17. PMID: 35581352.
• Safety considerations with the current treatments for peripheral T-cell lymphoma.Sethi T, Montanari F, Foss F. Expert Opin Drug Saf. 2022 May; 2022 Feb 6. PMID: 35129014.
• The potential of platelet-rich plasma injections and stem cell therapy for penile rejuvenation.Israeli JM, Lokeshwar SD, Efimenko IV, Masterson TA, Ramasamy R. Int J Impot Res. 2022 May; 2021 Nov 6. PMID: 34743193.
• Baseline Differences in Long-term Survivors and Nonsurvivors of the Colorado/Columbia Fetal Implant Trial.McRae C, Dunk M, Russell D, Ellgring H, Stern Y, Greene P, Fahn S, Henchcliffe C. J Int Neuropsychol Soc. 2022 May; 2021 Jun 14. PMID: 34121635.
• In vivo anti-tumor effect of PARP inhibition in IDH1/2 mutant MDS/AML resistant to targeted inhibitors of mutant IDH1/2.Gbyli R, Song Y, Liu W, Gao Y, Biancon G, Chandhok NS, Wang X, Fu X, Patel A, Sundaram R, Tebaldi T, Mamillapalli P, Zeidan AM, Flavell RA, Prebet T, Bindra RS, Halene S. Leukemia. 2022 May; 2022 Mar 10. PMID: 35273342.
• Author Correction: Expanded encyclopaedias of DNA elements in the human and mouse genomes.Moore JE, Purcaro MJ, Pratt HE, Epstein CB, Shoresh N, Adrian J, Kawli T, Davis CA, Dobin A, Kaul R, Halow J, Van Nostrand EL, Freese P, Gorkin DU, Shen Y, He Y, Mackiewicz M, Pauli-Behn F, Williams BA, Mortazavi A, Keller CA, Zhang XO, Elhajjajy SI, Huey J, Dickel DE, Snetkova V, Wei X, Wang X, Rivera-Mulia JC, Rozowsky J, Zhang J, Chhetri SB, Zhang J, Victorsen A, White KP, Visel A, Yeo GW, Burge CB, Lécuyer E, Gilbert DM, Dekker J, Rinn J, Mendenhall EM, Ecker JR, Kellis M, Klein RJ, Noble WS, Kundaje A, Guigó R, Farnham PJ, Cherry JM, Myers RM, Ren B, Graveley BR, Gerstein MB, Pennacchio LA, Snyder MP, Bernstein BE, Wold B, Hardison RC, Gingeras TR, Stamatoyannopoulos JA, Weng Z. Nature. 2022 May. PMID: 35474001.
• Design of protein-binding proteins from the target structure alone.Cao L, Coventry B, Goreshnik I, Huang B, Sheffler W, Park JS, Jude KM, Marković I, Kadam RU, Verschueren KHG, Verstraete K, Walsh STR, Bennett N, Phal A, Yang A, Kozodoy L, DeWitt M, Picton L, Miller L, Strauch EM, DeBouver ND, Pires A, Bera AK, Halabiya S, Hammerson B, Yang W, Bernard S, Stewart L, Wilson IA, Ruohola-Baker H, Schlessinger J, Lee S, Savvides SN, Garcia KC, Baker D. Nature. 2022 May; 2022 Mar 24. PMID: 35332283.
• Correction to: Hematopoietic Cell Transplantation Cures Adenosine Deaminase 2 Deficiency: Report on 30 Patients.Hashem H, Bucciol G, Ozen S, Unal S, Bozkaya IO, Akarsu N, Taskinen M, Koskenvuo M, Saarela J, Dimitrova D, Hickstein DD, Hsu AP, Holland SM, Krance R, Sasa G, Kumar AR, Müller I, de Sousa MA, Delafontaine S, Moens L, Babor F, Barzaghi F, Cicalese MP, Bredius R, van Montfrans J, Baretta V, Cesaro S, Stepensky P, Benedicte N, Moshous D, Le Guenno G, Boutboul D, Dalal J, Brooks JP, Dokmeci E, Dara J, Lucas CL, Hambleton S, Wilson K, Jolles S, Koc Y, Güngör T, Schnider C, Candotti F, Steinmann S, Schulz A, Chambers C, Hershfield M, Ombrello A, Kanakry JA, Meyts I. J Clin Immunol. 2022 Apr 30; 2022 Apr 30. PMID: 35499644.
• Decomposing a deterministic path to mesenchymal niche formation by two intersecting morphogen gradients.Qu R, Gupta K, Dong D, Jiang Y, Landa B, Saez C, Strickland G, Levinsohn J, Weng PL, Taketo MM, Kluger Y, Myung P. Dev Cell. 2022 Apr 25; 2022 Apr 13. PMID: 35421372.
• Chromatin profiling in human neurons reveals aberrant roles for histone acetylation and BET family proteins in schizophrenia.Farrelly LA, Zheng S, Schrode N, Topol A, Bhanu NV, Bastle RM, Ramakrishnan A, Chan JC, Cetin B, Flaherty E, Shen L, Gleason K, Tamminga CA, Garcia BA, Li H, Brennand KJ, Maze I. Nat Commun. 2022 Apr 22; 2022 Apr 22. PMID: 35459277.
• ZNF117 regulates glioblastoma stem cell differentiation towards oligodendroglial lineage.Liu J, Wang X, Chen AT, Gao X, Himes BT, Zhang H, Chen Z, Wang J, Sheu WC, Deng G, Xiao Y, Zou P, Zhang S, Liu F, Zhu Y, Fan R, Patel TR, Saltzman WM, Zhou J. Nat Commun. 2022 Apr 22; 2022 Apr 22. PMID: 35459228.
• Telomerase RNA TERC and the PI3K-AKT pathway form a positive feedback loop to regulate cell proliferation independent of telomerase activity.Wu S, Ge Y, Lin K, Liu Q, Zhou H, Hu Q, Zhao Y, He W, Ju Z. Nucleic Acids Res. 2022 Apr 22. PMID: 35323972.
• CALGB 40603 (Alliance): Long-Term Outcomes and Genomic Correlates of Response and Survival After Neoadjuvant Chemotherapy With or Without Carboplatin and Bevacizumab in Triple-Negative Breast Cancer.Shepherd JH, Ballman K, Polley MC, Campbell JD, Fan C, Selitsky S, Fernandez-Martinez A, Parker JS, Hoadley KA, Hu Z, Li Y, Soloway MG, Spears PA, Singh B, Tolaney SM, Somlo G, Port ER, Ma C, Kuzma C, Mamounas E, Golshan M, Bellon JR, Collyar D, Hahn OM, Hudis CA, Winer EP, Partridge A, Hyslop T, Carey LA, Perou CM, Sikov WM. J Clin Oncol. 2022 Apr 20; 2022 Jan 19. PMID: 35044810.
• Innovations in Stem Cell Therapy for Diabetic Wound Healing.Ho J, Yue D, Cheema U, Hsia HC, Dardik A. Adv Wound Care (New Rochelle). 2022 Apr 19; 2022 Apr 19. PMID: 35176896.
• Muscle LIM Protein Force-Sensing Mediates Sarcomeric Biomechanical Signaling in Human Familial Hypertrophic Cardiomyopathy.Riaz M, Park J, Sewanan LR, Ren Y, Schwan J, Das SK, Pomianowski PT, Huang Y, Ellis MW, Luo J, Liu J, Song L, Chen IP, Qiu C, Yazawa M, Tellides G, Hwa J, Young LH, Yang L, Marboe CC, Jacoby DL, Campbell SG, Qyang Y. Circulation. 2022 Apr 19; 2022 Apr 6. PMID: 35384713.
• The importance of considering regulatory domains in genome-wide analyses - the nearest gene is often wrong!Chua EHZ, Yasar S, Harmston N. Biol Open. 2022 Apr 15; 2022 Apr 4. PMID: 35377406.
• Naive T-Cell Depletion to Prevent Chronic Graft-Versus-Host Disease.Bleakley M, Sehgal A, Seropian S, Biernacki MA, Krakow EF, Dahlberg A, Persinger H, Hilzinger B, Martin PJ, Carpenter PA, Flowers ME, Voutsinas J, Gooley TA, Loeb K, Wood BL, Heimfeld S, Riddell SR, Shlomchik WD. J Clin Oncol. 2022 Apr 10; 2022 Jan 10. PMID: 35007144.
• A genome-scale gain-of-function CRISPR screen in CD8 T cells identifies proline metabolism as a means to enhance CAR-T therapy.Ye L, Park JJ, Peng L, Yang Q, Chow RD, Dong MB, Lam SZ, Guo J, Tang E, Zhang Y, Wang G, Dai X, Du Y, Kim HR, Cao H, Errami Y, Clark P, Bersenev A, Montgomery RR, Chen S. Cell Metab. 2022 Apr 5; 2022 Mar 10. PMID: 35276062.
• Insights of the role of estrogen in obesity from two models of ERα deletion.Saavedra-Peña RDM, Taylor N, Rodeheffer MS. J Mol Endocrinol. 2022 Apr 5; 2022 Apr 5. PMID: 35244608.
• Contribution of astrocytes to familial risk and clinical manifestation of schizophrenia.Koskuvi M, Lehtonen Š, Trontti K, Keuters M, Wu YC, Koivisto H, Ludwig A, Plotnikova L, Virtanen PLJ, Räsänen N, Kaipainen S, Hyötyläinen I, Dhungana H, Giniatullina R, Ojansuu I, Vaurio O, Cannon TD, Lönnqvist J, Therman S, Suvisaari J, Kaprio J, Lähteenvuo M, Tohka J, Giniatullin R, Rivera C, Hovatta I, Tanila H, Tiihonen J, Koistinaho J. Glia. 2022 Apr; 2021 Dec 22. PMID: 34936134.
• Immunopathological changes, complications, sequelae and immunological memory in COVID-19 patients.Yao L, Lu L, Ma W. Heliyon. 2022 Apr; 2022 Apr 26. PMID: 35497026.
• Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus.Duy PQ, Weise SC, Marini C, Li XJ, Liang D, Dahl PJ, Ma S, Spajic A, Dong W, Juusola J, Kiziltug E, Kundishora AJ, Koundal S, Pedram MZ, Torres-Fernández LA, Händler K, De Domenico E, Becker M, Ulas T, Juranek SA, Cuevas E, Hao LT, Jux B, Sousa AMM, Liu F, Kim SK, Li M, Yang Y, Takeo Y, Duque A, Nelson-Williams C, Ha Y, Selvaganesan K, Robert SM, Singh AK, Allington G, Furey CG, Timberlake AT, Reeves BC, Smith H, Dunbar A, DeSpenza T Jr, Goto J, Marlier A, Moreno-De-Luca A, Yu X, Butler WE, Carter BS, Lake EMR, Constable RT, Rakic P, Lin H, Deniz E, Benveniste H, Malvankar NS, Estrada-Veras JI, Walsh CA, Alper SL, Schultze JL, Paeschke K, Doetzlhofer A, Wulczyn FG, Jin SC, Lifton RP, Sestan N, Kolanus W, Kahle KT. Nat Neurosci. 2022 Apr; 2022 Apr 4. PMID: 35379995.
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• Brain charts for the human lifespan.Bethlehem RAI, Seidlitz J, White SR, Vogel JW, Anderson KM, Adamson C, Adler S, Alexopoulos GS, Anagnostou E, Areces-Gonzalez A, Astle DE, Auyeung B, Ayub M, Bae J, Ball G, Baron-Cohen S, Beare R, Bedford SA, Benegal V, Beyer F, Blangero J, Blesa Cábez M, Boardman JP, Borzage M, Bosch-Bayard JF, Bourke N, Calhoun VD, Chakravarty MM, Chen C, Chertavian C, Chetelat G, Chong YS, Cole JH, Corvin A, Costantino M, Courchesne E, Crivello F, Cropley VL, Crosbie J, Crossley N, Delarue M, Delorme R, Desrivieres S, Devenyi GA, Di Biase MA, Dolan R, Donald KA, Donohoe G, Dunlop K, Edwards AD, Elison JT, Ellis CT, Elman JA, Eyler L, Fair DA, Feczko E, Fletcher PC, Fonagy P, Franz CE, Galan-Garcia L, Gholipour A, Giedd J, Gilmore JH, Glahn DC, Goodyer IM, Grant PE, Groenewold NA, Gunning FM, Gur RE, Gur RC, Hammill CF, Hansson O, Hedden T, Heinz A, Henson RN, Heuer K, Hoare J, Holla B, Holmes AJ, Holt R, Huang H, Im K, Ipser J, Jack CR Jr, Jackowski AP, Jia T, Johnson KA, Jones PB, Jones DT, Kahn RS, Karlsson H, Karlsson L, Kawashima R, Kelley EA, Kern S, Kim KW, Kitzbichler MG, Kremen WS, Lalonde F, Landeau B, Lee S, Lerch J, Lewis JD, Li J, Liao W, Liston C, Lombardo MV, Lv J, Lynch C, Mallard TT, Marcelis M, Markello RD, Mathias SR, Mazoyer B, McGuire P, Meaney MJ, Mechelli A, Medic N, Misic B, Morgan SE, Mothersill D, Nigg J, Ong MQW, Ortinau C, Ossenkoppele R, Ouyang M, Palaniyappan L, Paly L, Pan PM, Pantelis C, Park MM, Paus T, Pausova Z, Paz-Linares D, Pichet Binette A, Pierce K, Qian X, Qiu J, Qiu A, Raznahan A, Rittman T, Rodrigue A, Rollins CK, Romero-Garcia R, Ronan L, Rosenberg MD, Rowitch DH, Salum GA, Satterthwaite TD, Schaare HL, Schachar RJ, Schultz AP, Schumann G, Schöll M, Sharp D, Shinohara RT, Skoog I, Smyser CD, Sperling RA, Stein DJ, Stolicyn A, Suckling J, Sullivan G, Taki Y, Thyreau B, Toro R, Traut N, Tsvetanov KA, Turk-Browne NB, Tuulari JJ, Tzourio C, Vachon-Presseau É, Valdes-Sosa MJ, Valdes-Sosa PA, Valk SL, van Amelsvoort T, Vandekar SN, Vasung L, Victoria LW, Villeneuve S, Villringer A, Vértes PE, Wagstyl K, Wang YS, Warfield SK, Warrier V, Westman E, Westwater ML, Whalley HC, Witte AV, Yang N, Yeo B, Yun H, Zalesky A, Zar HJ, Zettergren A, Zhou JH, Ziauddeen H, Zugman A, Zuo XN, Bullmore ET, Alexander-Bloch AF. Nature. 2022 Apr; 2022 Apr 6. PMID: 35388223.
• Chronic Administration of Thymoquinone Enhances Adult Hippocampal Neurogenesis and Improves Memory in Rats Via Regulating the BDNF Signaling Pathway.Al Mamun A, Matsuzaki K, Islam R, Hossain S, Hossain ME, Katakura M, Arai H, Shido O, Hashimoto M. Neurochem Res. 2022 Apr; 2021 Dec 2. PMID: 34855048.
• New concepts for generating interspecies chimeras using human pluripotent stem cells.De Los Angeles A, Wu J. Protein Cell. 2022 Apr; 2021 Oct 11. PMID: 34633640.
• Perioperative Outcomes in Pregnant Women Who Underwent Surgery for Adnexal Torsion.Ekici H, Okmen F, Imamoglu M, Hortu I, Akdemir A. Rev Bras Ginecol Obstet. 2022 Apr; 2022 Feb 9. PMID: 35139568.
• Generation of a CRISPR/Cas edited human induced pluripotent stem cell line DHMi005-A-1 carrying a patient-specific disease-causing point mutation in the TBX5 gene.Lahm H, Heinrich P, Zierler E, Dzilic E, Neb I, Luzius T, Doppler SA, Schneider S, Lange R, Krane M, Dreßen M. Stem Cell Res. 2022 Apr; 2022 Jan 27. PMID: 35121196.
• Outcomes of Allogeneic Hematopoietic Cell Transplantation in T Cell Prolymphocytic Leukemia: A Contemporary Analysis from the Center for International Blood and Marrow Transplant Research.Murthy HS, Ahn KW, Estrada-Merly N, Alkhateeb HB, Bal S, Kharfan-Dabaja MA, Dholaria B, Foss F, Gowda L, Jagadeesh D, Sauter C, Abid MB, Aljurf M, Awan FT, Bacher U, Badawy SM, Battiwalla M, Bredeson C, Cerny J, Chhabra S, Deol A, Diaz MA, Farhadfar N, Freytes C, Gajewski J, Gandhi MJ, Ganguly S, Grunwald MR, Halter J, Hashmi S, Hildebrandt GC, Inamoto Y, Jimenez-Jimenez AM, Kalaycio M, Kamble R, Krem MM, Lazarus HM, Lazaryan A, Maakaron J, Munshi PN, Munker R, Nazha A, Nishihori T, Oluwole OO, Ortí G, Pan DC, Patel SS, Pawarode A, Rizzieri D, Saba NS, Savani B, Seo S, Ustun C, van der Poel M, Verdonck LF, Wagner JL, Wirk B, Oran B, Nakamura R, Scott B, Saber W. Transplant Cell Ther. 2022 Apr; 2022 Jan 23. PMID: 35081472.
• Mucus sialylation determines intestinal host-commensal homeostasis.Yao Y, Kim G, Shafer S, Chen Z, Kubo S, Ji Y, Luo J, Yang W, Perner SP, Kanellopoulou C, Park AY, Jiang P, Li J, Baris S, Aydiner EK, Ertem D, Mulder DJ, Warner N, Griffiths AM, Topf-Olivestone C, Kori M, Werner L, Ouahed J, Field M, Liu C, Schwarz B, Bosio CM, Ganesan S, Song J, Urlaub H, Oellerich T, Malaker SA, Zheng L, Bertozzi CR, Zhang Y, Matthews H, Montgomery W, Shih HY, Jiang J, Jones M, Baras A, Shuldiner A, Gonzaga-Jauregui C, Snapper SB, Muise AM, Shouval DS, Ozen A, Pan KT, Wu C, Lenardo MJ. Cell. 2022 Mar 31; 2022 Mar 17. PMID: 35303419.
• Retinal Cell Transplantation, Biomaterials, and In Vitro Models for Developing Next-generation Therapies of Age-related Macular Degeneration.Rizzolo LJ, Nasonkin IO, Adelman RA. Stem Cells Transl Med. 2022 Mar 31. PMID: 35356975.
• Mesenchymal Stem/Stromal Cells and Their Role in Oxidative Stress Associated with Preeclampsia.Kusuma GD, Georgiou HM, Perkins AV, Abumaree MH, Brennecke SP, Kalionis B. Yale J Biol Med. 2022 Mar; 2022 Mar 31. PMID: 35370491.
• Rap1A, Rap1B, and β-Adrenergic Signaling in Autologous HCT: A Randomized Controlled Trial of Propranolol.Johnson AK, Lorimer EL, Szabo A, Wu R, Shah NN, D'Souza A, Chhabra S, Hamadani M, Dhakal B, Hari P, Rao S, Carlson K, Williams CL, Knight JM. Yale J Biol Med. 2022 Mar; 2022 Mar 31. PMID: 35370486.
• Awakening KDM5B to defeat leukemia.Chan LH, Yan Q. Proc Natl Acad Sci U S A. 2022 Mar 29; 2022 Mar 21. PMID: 35312367.
• The role of FYCO1-dependent autophagy in lens fiber cell differentiation.Khan SY, Ali M, Kabir F, Na CH, Delannoy M, Ma Y, Qiu C, Costello MJ, Hejtmancik JF, Riazuddin SA. Autophagy. 2022 Mar 28; 2022 Mar 28. PMID: 35343376.
• Monospecific and bispecific monoclonal SARS-CoV-2 neutralizing antibodies that maintain potency against B.1.617.Peng L, Hu Y, Mankowski MC, Ren P, Chen RE, Wei J, Zhao M, Li T, Tripler T, Ye L, Chow RD, Fang Z, Wu C, Dong MB, Cook M, Wang G, Clark P, Nelson B, Klein D, Sutton R, Diamond MS, Wilen CB, Xiong Y, Chen S. Nat Commun. 2022 Mar 28; 2022 Mar 28. PMID: 35347138.
• PUMILIO proteins promote colorectal cancer growth via suppressing p21.Gong Y, Liu Z, Yuan Y, Yang Z, Zhang J, Lu Q, Wang W, Fang C, Lin H, Liu S. Nat Commun. 2022 Mar 25; 2022 Mar 25. PMID: 35338151.
• m⁶A mRNA modification maintains colonic epithelial cell homeostasis via NF-κB-mediated antiapoptotic pathway.Zhang T, Ding C, Chen H, Zhao J, Chen Z, Chen B, Mao K, Hao Y, Roulis M, Xu H, Kluger Y, Zou Q, Ye Y, Zhan M, Flavell RA, Li HB. Sci Adv. 2022 Mar 25; 2022 Mar 25. PMID: 35333576.
• An infection-induced oxidation site regulates legumain processing and tumor growth.Kovalyova Y, Bak DW, Gordon EM, Fung C, Shuman JHB, Cover TL, Amieva MR, Weerapana E, Hatzios SK. Nat Chem Biol. 2022 Mar 24; 2022 Mar 24. PMID: 35332331.
• Progress in Bioengineering Strategies for Heart Regenerative Medicine.Häneke T, Sahara M. Int J Mol Sci. 2022 Mar 23; 2022 Mar 23. PMID: 35408844.
• Integrating mechanical signals into cellular identity.Carley E, King MC, Guo S. Trends Cell Biol. 2022 Mar 22; 2022 Mar 22. PMID: 35337714.
• Readily Available Tissue-Engineered Vascular Grafts Derived From Human Induced Pluripotent Stem Cells.Luo J, Qin L, Park J, Kural MH, Huang Y, Shi X, Riaz M, Wang J, Ellis MW, Anderson CW, Yuan Y, Ren Y, Yoder MC, Tellides G, Niklason LE, Qyang Y. Circ Res. 2022 Mar 18; 2022 Feb 22. PMID: 35189711.
• Coagulation factor V is a T-cell inhibitor expressed by leukocytes in COVID-19.Wang J, Kotagiri P, Lyons PA, Al-Lamki RS, Mescia F, Bergamaschi L, Turner L, Morgan MD, Calero-Nieto FJ, Bach K, Mende N, Wilson NK, Watts ER, Maxwell PH, Chinnery PF, Kingston N, Papadia S, Stirrups KE, Walker N, Gupta RK, Menon DK, Allinson K, Aitken SJ, Toshner M, Weekes MP, Nathan JA, Walmsley SR, Ouwehand WH, Kasanicki M, Göttgens B, Marioni JC, Smith KGC, Pober JS, Bradley JR. iScience. 2022 Mar 18; 2022 Feb 22. PMID: 35224470.
• Precision analysis of mutant U2AF1 activity reveals deployment of stress granules in myeloid malignancies.Biancon G, Joshi P, Zimmer JT, Hunck T, Gao Y, Lessard MD, Courchaine E, Barentine AES, Machyna M, Botti V, Qin A, Gbyli R, Patel A, Song Y, Kiefer L, Viero G, Neuenkirchen N, Lin H, Bewersdorf J, Simon MD, Neugebauer KM, Tebaldi T, Halene S. Mol Cell. 2022 Mar 17. PMID: 35303483.
• Evitar: designing anti-viral RNA therapies against future RNA viruses.Zhang D, Tian J, Wang Y, Lu J. Bioinformatics. 2022 Mar 16; 2022 Mar 16. PMID: 35294970.
• Insights into Binding of Single-Stranded Viral RNA Template to the Replication-Transcription Complex of SARS-CoV-2 for the Priming Reaction from Molecular Dynamics Simulations.Wang J, Shi Y, Reiss K, Allen B, Maschietto F, Lolis E, Konigsberg WH, Lisi GP, Batista VS. Biochemistry. 2022 Mar 15; 2022 Feb 24. PMID: 35199520.
• Therapeutic role of uterine-derived stem cells in acute kidney injury.Mamillapalli R, Cho S, Mutlu L, Taylor HS. Stem Cell Res Ther. 2022 Mar 12; 2022 Mar 12. PMID: 35279204.
• Pulmonary microbiome and gene expression signatures differentiate lung function in pediatric hematopoietic cell transplant candidates.Zinter MS, Versluys AB, Lindemans CA, Mayday MY, Reyes G, Sunshine S, Chan M, Fiorino EK, Cancio M, Prevaes S, Sirota M, Matthay MA, Kharbanda S, Dvorak CC, Boelens JJ, DeRisi JL. Sci Transl Med. 2022 Mar 9; 2022 Mar 9. PMID: 35263147.