2015
The Research Domain Criteria (RDoC) Project and Studies of Risk and Resilience in Maltreated Children
Kaufman J, Gelernter J, Hudziak JJ, Tyrka AR, Coplan JD. The Research Domain Criteria (RDoC) Project and Studies of Risk and Resilience in Maltreated Children. Journal Of The American Academy Of Child & Adolescent Psychiatry 2015, 54: 617-625. PMID: 26210330, PMCID: PMC4515569, DOI: 10.1016/j.jaac.2015.06.001.Peer-Reviewed Original ResearchConceptsResearch Domain Criteria projectNeural circuitsSubset of patientsRelevant animal modelsOnset of psychopathologyStress-related mechanismsClinical studiesStandard interventionAnimal modelsClinical implicationsMental disordersMaltreated childrenNeural circuitryTranslational researchPrecision medicinePsychiatric nomenclaturePatientsChildrenRDoC projectRDoC frameworkNeurobiological measuresRDoC initiativeRiskUltimate long-term goalStudy of risk
2011
The association of genetic variation in CACNA1C with structure and function of a frontotemporal system
Wang F, McIntosh AM, He Y, Gelernter J, Blumberg HP. The association of genetic variation in CACNA1C with structure and function of a frontotemporal system. Bipolar Disorders 2011, 13: 696-700. PMID: 22085483, PMCID: PMC3233238, DOI: 10.1111/j.1399-5618.2011.00963.x.Peer-Reviewed Original ResearchConceptsBipolar disorderFrontotemporal neural systemFunctional connectivityGG groupHigh-resolution structural magnetic resonance imaging scanMagnetic resonance imaging (MRI) scansNeural system effectsStructural magnetic resonance imaging (MRI) scansResonance imaging scansFunctional MRI scansGray matter volumeFunctional connectivity analysisNeural systemsGray matter morphologyCorticolimbic structuresImaging scansHigh riskMatter volumeMRI scansCACNA1C variationNeural circuitryCACNA1C geneSingle nucleotide polymorphismsConnectivity analysisAssociation