2013
Physiologic load-bearing characteristics of autografts, allografts, and polymer-based scaffolds in a critical sized segmental defect of long bone: an experimental study
Amorosa L, Lee C, Aydemir, Nizami S, Hsu A, Patel N, Gardner T, Navalgund A, Kim DG, Park S, Mao J, Lee F. Physiologic load-bearing characteristics of autografts, allografts, and polymer-based scaffolds in a critical sized segmental defect of long bone: an experimental study. International Journal Of Nanomedicine 2013, Volume 8: 1637-1643. PMID: 23637532, PMCID: PMC3639117, DOI: 10.2147/ijn.s42855.Peer-Reviewed Original ResearchConceptsAddition of hMSCsPolymer-based scaffoldsLoad-bearing characteristicsPhysiologic cyclic loadingPhase angleCritical-sized segmental defectsScaffold alone groupViscous stiffnessCyclic loadingMechanical propertiesFemoral defect modelSized segmental defectsRat femoral defect modelHuman mesenchymal stem cellsMechanical simulationsScaffold groupDifferent biomechanical characteristicsEnhanced bone formationHigh phase anglesDefect modelBiomechanical characteristicsExperimental studyHost boneStiffnessDefect repair
1998
Micromechanical Properties of Epiphyseal Trabecular Bone and Primary Spongiosa Around the Physis: An In Situ Nanoindentation Study
Lee F, Rho J, Harten R, Parsons J, Behrens F. Micromechanical Properties of Epiphyseal Trabecular Bone and Primary Spongiosa Around the Physis: An In Situ Nanoindentation Study. Journal Of Pediatric Orthopaedics 1998, 18: 582-585. PMID: 9746404, DOI: 10.1097/00004694-199809000-00004.Peer-Reviewed Original Research