2022
Noninvasive Quantitative PET Imaging in Humans of the Pancreatic Beta-Cell Mass Biomarkers VMAT2 and Dopamine D2/D3 Receptors In Vivo
Bini J, Carson R, Cline G. Noninvasive Quantitative PET Imaging in Humans of the Pancreatic Beta-Cell Mass Biomarkers VMAT2 and Dopamine D2/D3 Receptors In Vivo. Methods In Molecular Biology 2022, 2592: 61-74. PMID: 36507985, DOI: 10.1007/978-1-0716-2807-2_4.Peer-Reviewed Original ResearchConceptsPositron emission tomographyBeta-cell massFunctional beta-cell massDopamine D2/D3 receptorsD2/D3 receptorsBeta-cell lossType 2 diabetesEfficacy of therapeuticsQuantitative positron emission tomographyInsulin secretionDopamine receptorsD3 receptorsGlucose regulationPET radioligandEmission tomographyType 1Clinical usePET imagingReceptorsQuantitative PET imagingVMAT2Cellular transportersImagingVivoQuantitative imaging
2012
Radial k-space Acquisition Improves Robustness of MR-based Attenuation Maps for MR/PET Quantification in an Animal Imaging Study of the Abdomen
Bini J, Robson P, Calcagno C, Millon A, Lobatto M, Fayad Z. Radial k-space Acquisition Improves Robustness of MR-based Attenuation Maps for MR/PET Quantification in an Animal Imaging Study of the Abdomen. 2012, 1-6. DOI: 10.1109/spmb.2012.6469451.Peer-Reviewed Original ResearchMR/PET systemAttenuation mapRadial k-space acquisitionCartesian k-space trajectoriesReconstructed PET imagesAnimal imaging studiesK-space trajectoriesK-space acquisitionInterest-based comparisonPhoton attenuationPET systemPreclinical imagingAccurate segmentationPositron emission tomographyAttenuation correctionStandard segmentation algorithmsCartesian acquisitionExhibit artifactsPET quantificationQuantitative measurementsQuantitative positron emission tomography