2024
Towards a neurodevelopmental model of bipolar disorder: a critical review of trait- and state-related functional neuroimaging in adolescents and young adults
Colic L, Sankar A, Goldman D, Kim J, Blumberg H. Towards a neurodevelopmental model of bipolar disorder: a critical review of trait- and state-related functional neuroimaging in adolescents and young adults. Molecular Psychiatry 2024, 1-13. PMID: 39333385, DOI: 10.1038/s41380-024-02758-4.Peer-Reviewed Original ResearchFunctional magnetic resonance imagingVentral prefrontal cortexBipolar disorderPrefrontal cortexNeurodevelopmental modelBrain systemsMood statesFunctional magnetic resonance imaging studyModel of bipolar disorderProcessing of rewardAcute mood statesRegulation of emotionVentral cortical regionsYoung adultsFunctional imaging findingsTrait vulnerabilityMood episodesSyndromal BDNeuroimaging evidenceFunctional neuroanatomyBrain differencesNeuroimaging studiesNeurodevelopmental mechanismsPrecentral gyrusBrain regions
2019
A preliminary study of association between adolescent estradiol level and dorsolateral prefrontal cortex activity during emotion regulation
Chung YS, Poppe A, Novotny S, Epperson CN, Kober H, Granger DA, Blumberg HP, Ochsner K, Gross JJ, Pearlson G, Stevens MC. A preliminary study of association between adolescent estradiol level and dorsolateral prefrontal cortex activity during emotion regulation. Psychoneuroendocrinology 2019, 109: 104398. PMID: 31394491, PMCID: PMC6842698, DOI: 10.1016/j.psyneuen.2019.104398.Peer-Reviewed Original ResearchConceptsDorsolateral prefrontal cortexNegative emotionsDLPFC activityDorsolateral prefrontal cortex activityHuman functional neuroimaging studiesFunctional magnetic resonance imagingPrefrontal cortex activityFunctional neuroimaging studiesCognitive reappraisalCognitive controlEmotion regulationCognitive processingCognitive processesCognitive strategiesEmotional experienceDLPFC functionNeuroimaging studiesDLPFC regionCortex activityEstradiol's rolePrefrontal cortexCortical systemsEmotionsAdolescent girlsActive attempts
2009
Functional and Structural Connectivity Between the Perigenual Anterior Cingulate and Amygdala in Bipolar Disorder
Wang F, Kalmar JH, He Y, Jackowski M, Chepenik LG, Edmiston E, Tie K, Gong G, Shah MP, Jones M, Uderman J, Constable RT, Blumberg HP. Functional and Structural Connectivity Between the Perigenual Anterior Cingulate and Amygdala in Bipolar Disorder. Biological Psychiatry 2009, 66: 516-521. PMID: 19427632, PMCID: PMC2830492, DOI: 10.1016/j.biopsych.2009.03.023.Peer-Reviewed Original ResearchConceptsPerigenual anterior cingulate cortexHealthy comparison subjectsBipolar disorderFunctional magnetic resonance imagingDiffusion tensor imagingFunctional connectivityWhite matterFractional anisotropyHC groupPerigenual anterior cingulateAnterior cingulate cortexMagnetic resonance imagingGray matter structuresRegional fractional anisotropyWhite matter connectivityEmotional processingFunctional connectivity measuresSignificant positive associationBD groupComparison subjectsAnterior cingulateCingulate cortexResonance imagingSignificant associationBrain regions