2024
Label-free Imaging with Photonic Crystal Surface for Hematopoietic Stem Cell Differentiation
Zhuo Y, Choi J, Marin T, Yu H, Harley B, Cunningham B. Label-free Imaging with Photonic Crystal Surface for Hematopoietic Stem Cell Differentiation. 2024, jm4a.19. DOI: 10.1364/translational.2024.jm4a.19.Peer-Reviewed Original Research
2018
Quantitative analysis of focal adhesion dynamics using photonic resonator outcoupler microscopy (PROM)
Zhuo Y, Choi J, Marin T, Yu H, Harley B, Cunningham B. Quantitative analysis of focal adhesion dynamics using photonic resonator outcoupler microscopy (PROM). Light: Science & Applications 2018, 7: 9. PMID: 29963322, PMCID: PMC6020849, DOI: 10.1038/s41377-018-0001-5.Peer-Reviewed Original ResearchFocal adhesion dynamicsFocal adhesion areaFocal adhesion formationPhotonic crystal biosensorCell surface contactFocal adhesionsReflection peak intensityAdhesion dynamicsRegulate adhesionCell membrane componentsCell-surface interactionsLabel-free modalityEvanescent fieldMembrane componentsLabel-free approachMigration speedPeak intensityCluster dimensionCell interactionsQuantitative imagingBasement membraneAdhesion areaEpithelial stem cellsPhotonsCellsPhotonic Resonator Outcoupler Microscopy (PROM) for Quantitative Monitoring of Stem Cell Focal Adhesion Area
Zhuo Y, Choi J, Marin T, Yu H, Harley B, Cunningham B. Photonic Resonator Outcoupler Microscopy (PROM) for Quantitative Monitoring of Stem Cell Focal Adhesion Area. 2018, jtu3a.119. DOI: 10.1364/fio.2018.jtu3a.119.Peer-Reviewed Original Research
2017
Label-free Imaging of Stem Cell Adhesion and Dynamic Tracking of Boundary Evolution Using Photonic Crystal Enhanced Microscopy (PCEM)
Zhuo Y, Choi J, Marin T, Yu H, Harley B, Cunningham B. Label-free Imaging of Stem Cell Adhesion and Dynamic Tracking of Boundary Evolution Using Photonic Crystal Enhanced Microscopy (PCEM). Microscopy And Microanalysis 2017, 23: 1142-1143. DOI: 10.1017/s1431927617006377.Peer-Reviewed Original ResearchQuantitative Label-free Imaging of Live-cell Adhesion Using Photonic Crystal Enhanced Microscopy (PCEM)
Zhuo Y, Choi J, Marin T, Yu H, Harley B, Cunningham B. Quantitative Label-free Imaging of Live-cell Adhesion Using Photonic Crystal Enhanced Microscopy (PCEM). 2017, sm1c.2. DOI: 10.1364/cleo_si.2017.sm1c.2.Peer-Reviewed Original Research
2015
Label-Free Biosensor Imaging on Photonic Crystal Surfaces
Zhuo Y, Cunningham B. Label-Free Biosensor Imaging on Photonic Crystal Surfaces. Sensors 2015, 15: 21613-21635. PMID: 26343684, PMCID: PMC4610529, DOI: 10.3390/s150921613.Peer-Reviewed Original ResearchConceptsPhotonic crystal surfaceCrystal surfaceImaging detection instrumentMetal plasmonic nanoparticlesDielectric nanoparticlesPhotobleachable fluorescent dyesOptical scatteringDielectric permittivityNanostructure designSensing resolutionOperating principleSubstrate surfaceCytotoxic stainsOptical microscopyPlasmonic nanoparticlesBiomaterial interactionsMatrix surfaceBiomolecular layerDetection instrumentKinetic monitoringPhotonsLabel-freeNanoparticlesSurfaceNanoparticle contrast agents
2013
Photonic crystal enhanced microscopy for imaging of live cell adhesion
Chen W, Long K, Lu M, Chaudhery V, Yu H, Choi J, Polans J, Zhuo Y, Harley B, Cunningham B. Photonic crystal enhanced microscopy for imaging of live cell adhesion. Analyst 2013, 138: 5886-5894. PMID: 23971078, DOI: 10.1039/c3an01541f.Peer-Reviewed Original ResearchConceptsTime-resolved imagingPhotonic crystalsRelevant time-scalesTime-scalesDrug-induced apoptosisSubmicron resolutionSpatial resolutionMorphological signaturesStem cell differentiationCell-surface interactionsFilopodial extensionsPhotonsCell adhesionCell differentiationDynamic informationCell attachmentLiving cell adhesionMonitor cell behaviorCell behaviorBiological phenomenaResolutionApoptosisEvolutionChemotaxisLabel-free