2018
Quantitative analysis of focal adhesion dynamics using photonic resonator outcoupler microscopy (PROM)
Zhuo Y, Choi J, Marin T, Yu H, Harley B, Cunningham B. Quantitative analysis of focal adhesion dynamics using photonic resonator outcoupler microscopy (PROM). Light: Science & Applications 2018, 7: 9. PMID: 29963322, PMCID: PMC6020849, DOI: 10.1038/s41377-018-0001-5.Peer-Reviewed Original ResearchFocal adhesion dynamicsFocal adhesion areaFocal adhesion formationPhotonic crystal biosensorCell surface contactFocal adhesionsReflection peak intensityAdhesion dynamicsRegulate adhesionCell membrane componentsCell-surface interactionsLabel-free modalityEvanescent fieldMembrane componentsLabel-free approachMigration speedPeak intensityCluster dimensionCell interactionsQuantitative imagingBasement membraneAdhesion areaEpithelial stem cellsPhotonsCells
2013
Photonic crystal enhanced microscopy for imaging of live cell adhesion
Chen W, Long K, Lu M, Chaudhery V, Yu H, Choi J, Polans J, Zhuo Y, Harley B, Cunningham B. Photonic crystal enhanced microscopy for imaging of live cell adhesion. Analyst 2013, 138: 5886-5894. PMID: 23971078, DOI: 10.1039/c3an01541f.Peer-Reviewed Original ResearchConceptsTime-resolved imagingPhotonic crystalsRelevant time-scalesTime-scalesDrug-induced apoptosisSubmicron resolutionSpatial resolutionMorphological signaturesStem cell differentiationCell-surface interactionsFilopodial extensionsPhotonsCell adhesionCell differentiationDynamic informationCell attachmentLiving cell adhesionMonitor cell behaviorCell behaviorBiological phenomenaResolutionApoptosisEvolutionChemotaxisLabel-free