Homeostatic Plasticity Hypothesis and Mechanisms of Neocortical Epilepsies
Kapur J, Trotter S. Homeostatic Plasticity Hypothesis and Mechanisms of Neocortical Epilepsies. Epilepsy Currents 2005, 5: 133-135. PMID: 16151520, PMCID: PMC1198733, DOI: 10.1111/j.1535-7511.2005.00042.x.Peer-Reviewed Original ResearchInhibitory postsynaptic currentsExcitatory postsynaptic currentsPostsynaptic currentsDevelopmental cortical malformationsHomeostatic synaptic plasticityBurst dischargesPosttraumatic epileptogenesisPyramidal cellsSpontaneous inhibitory postsynaptic current frequencyRat modelExcitatory synapsesInhibitory postsynaptic current frequencyModel of posttraumatic epileptogenesisEvoked inhibitory postsynaptic currentsMiniature excitatory postsynaptic currentsSynaptic plasticityControl cortexLayer V pyramidal neuronsEpileptiform burst dischargesPostsynaptic current frequencySpontaneous burst dischargesFunctional excitatory synapsesFour-layered microgyriaMechanisms of posttraumatic epileptogenesisEpileptiform-like activity