2020
Corticosteroids to prevent kidney scarring in children with a febrile urinary tract infection: a randomized trial
Shaikh N, Shope T, Hoberman A, Muniz G, Bhatnagar S, Nowalk A, Hickey R, Michaels M, Kearney D, Rockette H, Charron M, Lim R, Majd M, Shalaby-Rana E, Kurs-Lasky M, Cohen D, Wald E, Lockhart G, Pohl H, Martin J. Corticosteroids to prevent kidney scarring in children with a febrile urinary tract infection: a randomized trial. Pediatric Nephrology 2020, 35: 2113-2120. PMID: 32556960, PMCID: PMC7529851, DOI: 10.1007/s00467-020-04622-3.Peer-Reviewed Original ResearchConceptsFebrile urinary tract infectionUrinary tract infectionAdjuvant systemic corticosteroidsKidney scarringSystemic corticosteroidsTract infectionsInitiate urinary tract infectionReducing kidney scarringEfficacy of corticosteroidsMethodsChildren aged 2Absolute risk reductionRandomized to corticosteroidsMonths to 6Statistically significant differencePlacebo groupAdjuvant corticosteroidsCorticosteroidsKidney scansPlaceboSignificant differenceAged 2ScarsKidneyInfectionMonths
2010
Intranasal fentanyl versus placebo for pain in children during catheterization for voiding cystourethrography
Chung S, Lim R, Goldman R. Intranasal fentanyl versus placebo for pain in children during catheterization for voiding cystourethrography. Pediatric Radiology 2010, 40: 1236-1240. PMID: 20180109, DOI: 10.1007/s00247-009-1521-1.Peer-Reviewed Original ResearchConceptsStatistically significant differenceIN fentanylDecrease painFaces Pain Score-RevisedPediatric tertiary care centreDouble-blind randomized controlled trialPediatric tertiary centerSignificant differenceTertiary care centreYears of ageRandomized controlled trialsVoiding cystourethrographyIntranasal fentanylTertiary centerUrinary catheterVCUGCatheterizationCare centreFentanylPainControl groupChildren 4PlaceboSterile waterIntranasal