2021
Deep learning-based GTV contouring modeling inter- and intra- observer variability in sarcomas
Marin T, Zhuo Y, Lahoud R, Tian F, Ma X, Xing F, Moteabbed M, Liu X, Grogg K, Shusharina N, Woo J, Lim R, Ma C, Chen Y, El Fakhri G. Deep learning-based GTV contouring modeling inter- and intra- observer variability in sarcomas. Radiotherapy And Oncology 2021, 167: 269-276. PMID: 34808228, PMCID: PMC8934266, DOI: 10.1016/j.radonc.2021.09.034.Peer-Reviewed Original ResearchMeSH KeywordsDeep LearningHumansObserver VariationRadiotherapy Planning, Computer-AssistedReproducibility of ResultsSarcomaSoft Tissue NeoplasmsConceptsGross tumor volumeRadiation therapy treatment planningGross tumor volume contoursGross tumor volume delineationTherapy treatment planningIntra-observer variabilityConsensus contoursGTV contoursPre-operative CT imagesSoft tissue sarcomasRadiation oncologistsTumor volumeBone sarcomasTreatment planningAccurate contoursCT imagesDelineation procedureSarcomaSoft tissueConfidence levelRadiationPatientsHausdorff distanceMultiple contoursX-rayValidation of the Radiographic Global Impression of Change (RGI-C) score to assess healing of rickets in pediatric X-linked hypophosphatemia (XLH)
Lim R, Shailam R, Hulett R, Skrinar A, Nixon A, Williams A, Nixon M, Thacher T. Validation of the Radiographic Global Impression of Change (RGI-C) score to assess healing of rickets in pediatric X-linked hypophosphatemia (XLH). Bone 2021, 148: 115964. PMID: 33878504, DOI: 10.1016/j.bone.2021.115964.Peer-Reviewed Original ResearchMeSH KeywordsAlkaline PhosphataseAntibodies, MonoclonalChildFamilial Hypophosphatemic RicketsHumansImmunoglobulin GReproducibility of ResultsConceptsRickets Severity ScaleInter-rater reliabilityGlobal Impression of ChangeX-linked hypophosphatemiaIntra-raterImpression of ChangeRadiographic Global Impression of ChangeGlobal scoreRGI-CModerate to almost perfect agreementStandardized response meanIntra-rater reliabilityAlmost perfect agreementWeighted kappa valuesResponse meanChange scoresStanding heightBaseline to weekLeg scoreHealing of ricketsSeverity ScalePerfect agreementRickets severityBurosumab treatmentKappa values
2014
Dose reduction in pediatric abdominal CT: use of iterative reconstruction techniques across different CT platforms
Khawaja R, Singh S, Otrakji A, Padole A, Lim R, Nimkin K, Westra S, Kalra M, Gee M. Dose reduction in pediatric abdominal CT: use of iterative reconstruction techniques across different CT platforms. Pediatric Radiology 2014, 45: 1046-1055. PMID: 25427434, DOI: 10.1007/s00247-014-3235-2.Peer-Reviewed Original ResearchConceptsIterative reconstruction techniqueSinogram-affirmed iterative reconstructionAdaptive statistical iterative reconstructionModel-based iterative reconstructionPediatric abdominal CTDose reductionIterative reconstructionAbdominal CTAdaptive iterative dose reductionMagnitude of dose reductionIncreased image noiseStatistical iterative reconstructionAIDR 3DReconstruction techniqueCT examinationsCT scanImage noiseReconstruction algorithmClinical settingDosing potentialClinical applicationImage qualityRadiology communityReconstruction principleImage interpretation