2022
The role of renal contour change in the diagnosis of cortical scarring after urinary tract infection.
Muniz G, Charron M, Lim R, Shammas A, Liu H, Shaikh N. The role of renal contour change in the diagnosis of cortical scarring after urinary tract infection. American Journal Of Nuclear Medicine And Molecular Imaging 2022, 12: 41-43. PMID: 35295886, PMCID: PMC8918400.Peer-Reviewed Original ResearchUrinary tract infectionRenal scarringTract infectionsRenal contourDiagnosis of renal scarringPermanent renal scarringProspective clinical trialFollow-up scansNuclear medicine physiciansTechnetium-99mPresence of abnormalitiesRIVUR studyContour abnormalitiesCortical scarringClinical trialsTechnetium-99Medicine physiciansGold standardEligibility criteriaScarsContour changesAbnormalitiesDiagnosisInfectionChildren
2020
Corticosteroids to prevent kidney scarring in children with a febrile urinary tract infection: a randomized trial
Shaikh N, Shope T, Hoberman A, Muniz G, Bhatnagar S, Nowalk A, Hickey R, Michaels M, Kearney D, Rockette H, Charron M, Lim R, Majd M, Shalaby-Rana E, Kurs-Lasky M, Cohen D, Wald E, Lockhart G, Pohl H, Martin J. Corticosteroids to prevent kidney scarring in children with a febrile urinary tract infection: a randomized trial. Pediatric Nephrology 2020, 35: 2113-2120. PMID: 32556960, PMCID: PMC7529851, DOI: 10.1007/s00467-020-04622-3.Peer-Reviewed Original ResearchConceptsFebrile urinary tract infectionUrinary tract infectionAdjuvant systemic corticosteroidsKidney scarringSystemic corticosteroidsTract infectionsInitiate urinary tract infectionReducing kidney scarringEfficacy of corticosteroidsMethodsChildren aged 2Absolute risk reductionRandomized to corticosteroidsMonths to 6Statistically significant differencePlacebo groupAdjuvant corticosteroidsCorticosteroidsKidney scansPlaceboSignificant differenceAged 2ScarsKidneyInfectionMonths