2020
Spectral editing in 1H magnetic resonance spectroscopy: Experts' consensus recommendations
Choi I, Andronesi O, Barker P, Bogner W, Edden R, Kaiser L, Lee P, Marjańska M, Terpstra M, de Graaf R. Spectral editing in 1H magnetic resonance spectroscopy: Experts' consensus recommendations. NMR In Biomedicine 2020, 34: e4411. PMID: 32946145, PMCID: PMC8557623, DOI: 10.1002/nbm.4411.Peer-Reviewed Original ResearchConceptsSpectral editingIn vivo<sup>1</sup>H MRS, paMulticenter clinical trialSpectral fittingExpert consensus recommendationsD-2-hydroxyglutarateJ-couplingG-aminobutyric acidH-MRSFrequency driftClinical trialsSignal overlapConsensus recommendationsMagnetic resonance spectroscopyMetabolite signalsResonance spectroscopyResonanceExpert recommendationsSequence parameters
2017
Measurement of lipid composition in human skeletal muscle and adipose tissue with 1H‐MRS homonuclear spectral editing
Lindeboom L, de Graaf R. Measurement of lipid composition in human skeletal muscle and adipose tissue with 1H‐MRS homonuclear spectral editing. Magnetic Resonance In Medicine 2017, 79: 619-627. PMID: 28474367, DOI: 10.1002/mrm.26740.Peer-Reviewed Original ResearchConceptsAdipose tissueProton magnetic resonance spectroscopySkeletal muscleH-MRSAccumulation of triglyceridesInvasive biopsyMetabolic derangementsEctopic fatInsulin resistanceCardiovascular diseaseMetabolic diseasesMEGA-sLASER sequenceIn vivoNonadipose tissuesLipid resonancesSpectral editingPolyunsaturated fatty acidsHuman skeletal muscleMagnetic resonance spectroscopyLipid storesLipid compositionAdiposeSpectral resolutionTissuePhantom experiments