2009
Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy
Berg AT, Mathern GW, Bronen RA, Fulbright RK, DiMario F, Testa FM, Levy SR. Frequency, prognosis and surgical treatment of structural abnormalities seen with magnetic resonance imaging in childhood epilepsy. Brain 2009, 132: 2785-2797. PMID: 19638447, PMCID: PMC2759335, DOI: 10.1093/brain/awp187.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAge of OnsetAnticonvulsantsBrainChildChild, PreschoolCognitionCohort StudiesDrug ResistanceEpilepsyFemaleFunctional LateralityHumansImage Processing, Computer-AssistedInfantLogistic ModelsMagnetic Resonance ImagingMaleNeurologic ExaminationNeuropsychological TestsNeurosurgical ProceduresPrognosisSclerosisTomography, X-Ray ComputedConceptsMagnetic resonance imagingPositive MRI scansEpilepsy patientsMRI scansEpilepsy syndromesEpilepsy evaluationSurgical proceduresMultiple logistic regression analysisUse of MRIComprehensive epilepsy evaluationNon-idiopathic patientsPediatric epilepsy patientsComprehensive Epilepsy CenterPositive MRI findingsCommunity-based cohortNormal neurological examPre-surgical evaluationLogistic regression analysisIdiopathic epilepsy syndromesFrequency of lesionsClinical factorsMRI abnormalitiesMRI findingsNeurological examSurgical treatment
2006
Volumetry of amygdala and hippocampus and memory performance in Alzheimer's disease
Basso M, Yang J, Warren L, MacAvoy MG, Varma P, Bronen RA, van Dyck CH. Volumetry of amygdala and hippocampus and memory performance in Alzheimer's disease. Psychiatry Research 2006, 146: 251-261. PMID: 16524704, DOI: 10.1016/j.pscychresns.2006.01.007.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingAD patientsAmygdaloid volumesAlzheimer's diseaseHealthy controlsHippocampal volumeAlzheimer's Disease Assessment Scale-CognitionMedial temporal lobe atrophyTemporal lobe atrophyOlder healthy subjectsADAS-Cog subscaleHealthy control samplesLobe atrophyAD groupHealthy subjectsAnalysis of covarianceMRI studiesProdromal stagePatientsResonance imagingMildest symptomsNeuropsychological assessmentNeuropsychological performanceHippocampusDisease
2004
Long-term outcome after epilepsy surgery for focal cortical dysplasia.
Cohen-Gadol AA, Ozduman K, Bronen RA, Kim JH, Spencer DD. Long-term outcome after epilepsy surgery for focal cortical dysplasia. Journal Of Neurosurgery 2004, 101: 55-65. PMID: 15255252, DOI: 10.3171/jns.2004.101.1.0055.Peer-Reviewed Original ResearchConceptsFocal cortical dysplasiaImproved seizure outcomeLong-term outcomesCortical dysplasiaClear marginsEpileptogenic zoneSeizure outcomeMean ageMean durationRisk factorsCortical developmentIntracranial monitoringObvious risk factorsRare disabling seizuresTransient sensorimotor deficitsMultiple subpial transectionsSubgroup of patientsExtent of resectionVisual field defectsInclusion of patientsNormal functional anatomyReports of outcomesMagnetic resonance imagingFunctional MR imagingPartial lesionectomy
1998
Development and Reliability of a Method for Using Magnetic Resonance Imaging for the Definition of Regions of Interest for Positron Emission Tomography
Bremner JD, Bronen RA, De Erasquin G, Vermetten E, Staib LH, Ng CK, Soufer R, Charney DS, Innis RB. Development and Reliability of a Method for Using Magnetic Resonance Imaging for the Definition of Regions of Interest for Positron Emission Tomography. Molecular Imaging And Biology 1998, 1: 145-159. PMID: 14516589, DOI: 10.1016/s1095-0397(98)00015-6.Peer-Reviewed Original ResearchMagnetic resonance imagingPositron emission tomographyCoregistered magnetic resonance imagingResonance imagingBrain regionsEmission tomographyPoor anatomical resolutionAnatomical resolutionRegional metabolic rateBrain metabolic rateIntra-class correlation coefficientSuperior anatomical resolutionPET scansMRI scansMetabolic rateBrain scansPhysiologic informationAnatomical landmarksPET brain imagesReliable methodPets siteIndependent ratersScansImportant physiological informationStandard anatomical atlas
1997
Topographic distribution of seizure onset and hippocampal atrophy: Relationship between MRI and depth EEG
King D, Bronen R, Spencer D, Spencer S. Topographic distribution of seizure onset and hippocampal atrophy: Relationship between MRI and depth EEG. Clinical Neurophysiology 1997, 103: 692-697. PMID: 9546496, DOI: 10.1016/s0013-4694(97)00090-4.Peer-Reviewed Original ResearchConceptsMedial temporal lobe epilepsyMagnetic resonance imagingSegmental atrophyHippocampal atrophyIctal onsetCell lossTopographic distributionDepth EEGHippocampal cell lossAnterior temporal lobectomyTemporal lobe epilepsyHippocampal depth electrodesMedial temporal structuresDistribution of onsetMost patientsTemporal lobectomyFocal onsetLobe epilepsyExcellent outcomesIctal recordingsDentate gyrusHippocampal segmentsSeizure onsetSubdural stripsDepth electrode contactsPostoperative changes in the brain: MR imaging findings in patients without neoplasms.
Sato N, Bronen R, Sze G, Kawamura Y, Coughlin W, Putman C, Spencer D. Postoperative changes in the brain: MR imaging findings in patients without neoplasms. Radiology 1997, 204: 839-46. PMID: 9280269, DOI: 10.1148/radiology.204.3.9280269.Peer-Reviewed Original ResearchConceptsPostoperative MR imagesPostoperative changesDural enhancementEnhancement patternThin linear enhancementContrast enhancement patternMagnetic resonance imagingMR imagesSurgical marginsTemporal lobectomyNeoplastic changesExtraaxial fluidIntracranial airContrast material-enhanced MR imagesDay 5Day 51Day 30Resonance imagingSurgeryBrainPatientsTime courseContrast enhancementLinear enhancementDaysPredicting Reading Performance From Neuroimaging Profiles: The Cerebral Basis of Phonological Effects in Printed Word Identification
Pugh K, Shaywitz B, Shaywitz S, Shankweiler D, Katz L, Fletcher J, Skudlarski P, Fulbright R, Constable R, Bronen R, Lacadie C, Gore J. Predicting Reading Performance From Neuroimaging Profiles: The Cerebral Basis of Phonological Effects in Printed Word Identification. Journal Of Experimental Psychology Human Perception & Performance 1997, 23: 299-318. PMID: 9103996, DOI: 10.1037/0096-1523.23.2.299.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingPhonological effectsLexical decision taskLexical decision latenciesLexical-semantic processesBrain activation patternsWord identificationWord recognitionDecision taskDecision latenciesRegularity effectIndividual differencesFMRI measuresHemispheric lateralizationCerebral basisExperimental paradigmActivation patternsCortical regionsLength effectYoung adultsTaskParticipantsReadingMeasuresMagnetic resonance imagingMagnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report
Bremner J, Randall P, Vermetten E, Staib L, Bronen R, Mazure C, Capelli S, McCarthy G, Innis R, Charney D. Magnetic resonance imaging-based measurement of hippocampal volume in posttraumatic stress disorder related to childhood physical and sexual abuse—a preliminary report. Biological Psychiatry 1997, 41: 23-32. PMID: 8988792, PMCID: PMC3229101, DOI: 10.1016/s0006-3223(96)00162-x.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderLeft hippocampal volumeHippocampal volumeChildhood abuseAdult survivorsSmaller left hippocampal volumeAbuse-related posttraumatic stress disorderStress disorderSmaller hippocampal volumesCombat-related posttraumatic stress disorderMagnetic resonance imagingShort-term memoryHealthy subjectsYears of educationAlcohol abuseMagnetic resonance imaging-based measurementsComparison subjectsPTSD patientsImaging-based measurementsResonance imagingPatientsSexual abusePreliminary reportSurvivorsComparison region
1995
MRI-based measurement of hippocampal volume in patients with combat- related posttraumatic stress disorder
Bremner J, Randall P, Scott T, Bronen R, Seibyl J, Southwick S, Delaney R, McCarthy G, Charney D, Innis R. MRI-based measurement of hippocampal volume in patients with combat- related posttraumatic stress disorder. American Journal Of Psychiatry 1995, 152: 973-981. PMID: 7793467, PMCID: PMC3233767, DOI: 10.1176/ajp.152.7.973.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderCombat-related posttraumatic stress disorderSmaller right hippocampal volumeRight hippocampal volumeVerbal memoryHippocampal volumeStress disorderPTSD patientsShort-term verbal memoryShort-term memoryWechsler Memory ScaleComparison subjectsVietnam combat veteransMemory ScaleCombat veteransYears of educationMagnetic resonance imagingBrain regionsMemoryBrain structuresFunctional deficitsNeurotoxic effectsPsychiatric disordersAlcohol abusePatients
1992
Efficacy of Gadoteridol for Magnetic Resonance Imaging of the Brain and Spine
RUNGE V, BRONEN R, DAVIS K. Efficacy of Gadoteridol for Magnetic Resonance Imaging of the Brain and Spine. Investigative Radiology 1992, 27: s33. PMID: 1506150, DOI: 10.1097/00004424-199208001-00006.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingEfficacy of gadoteridolResonance imagingCentral nervous system pathologyMulticenter clinical trialNervous system pathologyIntravenous contrast agentsMagnetic resonance scansVisualization of pathologyRadiologic evidencePostcontrast scansSpinal lesionsClinical trialsIntravenous administrationPathologic lesionsSpinal pathologySystem pathologyResonance scansPrecontrast imagesSpinal casesIntracranial casesPathologyGadoteridolLesion bordersPatients
1991
MRI of the temporal lobe: Normal variations, with special reference toward epilepsy
Bronen R, Cheung G. MRI of the temporal lobe: Normal variations, with special reference toward epilepsy. Magnetic Resonance Imaging 1991, 9: 501-507. PMID: 1779721, DOI: 10.1016/0730-725x(91)90036-l.Peer-Reviewed Original ResearchConceptsMagnetic resonance imagingTemporal hornTemporal lobeCollateral sulcusCoronal magnetic resonance imagingTemporal horn dilatationMild asymmetryRight temporal lobeTemporal lobe structuresHippocampal sclerosisChoroidal fissureNormal variationMild enlargementFrequent findingHippocampal headNormal volunteersWhite matterAlzheimer's diseaseResonance imagingLobe structuresOccipitotemporal sulcusAdjacent vesselsHead rotationSclerosisSulcusRelationship of hippocampus and amygdala to coronal MRI landmarks
Bronen R, Cheung G. Relationship of hippocampus and amygdala to coronal MRI landmarks. Magnetic Resonance Imaging 1991, 9: 449-457. PMID: 1881265, DOI: 10.1016/0730-725x(91)90434-n.Peer-Reviewed Original Research
1990
Magnetic resonance imaging contrast agents: theory and application to the central nervous system.
Bronen R, Sze G. Magnetic resonance imaging contrast agents: theory and application to the central nervous system. Journal Of Neurosurgery 1990, 73: 820-39. PMID: 2230966, DOI: 10.3171/jns.1990.73.6.0820.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCentral nervous systemComputerized tomographyMR imagingNervous systemContrast-enhanced computerized tomographyActive multiple sclerosisIntradural spinal neoplasmsSecondary brain tumorsCerebral blood flowContrast-enhanced MR imagingContrast agentsIntrathecal contrast mediumStudy of choiceMagnetic resonanceMagnetic resonance imagingSignal intensity changesCNS lesionsMultiple sclerosisPituitary lesionsPostoperative stateAcoustic neurinomaSpinal neoplasmsMore abnormalitiesBlood flowSpinal disease