Multiple-Shooting Adjoint Method for Whole-Brain Dynamic Causal Modeling
Zhuang J, Dvornek N, Tatikonda S, Papademetris X, Ventola P, Duncan J. Multiple-Shooting Adjoint Method for Whole-Brain Dynamic Causal Modeling. Lecture Notes In Computer Science 2021, 12729: 58-70. DOI: 10.1007/978-3-030-78191-0_5.Peer-Reviewed Original ResearchOrdinary differential equationsAdjoint methodNoisy observationsMultiple shooting methodNon-linear systemsLarge scale continuous systemsLarge-scale systemsParameter value estimationDifferential equationsAccurate gradient estimationExpectation-maximization algorithmNon-linear modelParameter estimationBayesian frameworkGradient estimationContinuous systemToy exampleLarge systemsReal fMRI dataEstimationValue estimationAlgorithmGood accuracyCausal modelingModel changes