2007
Distribution volume as an alternative to the binding potential for sigma1 receptor imaging
Kimura Y, Naganawa M, Sakata M, Ishikawa M, Mishina M, Oda K, Ishii K, Ishiwata K. Distribution volume as an alternative to the binding potential for sigma1 receptor imaging. Annals Of Nuclear Medicine 2007, 21: 533-535. PMID: 18030587, DOI: 10.1007/s12149-007-0063-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAnatomy, RegionalBrainBrain MappingCarbon RadioisotopesData Interpretation, StatisticalFemaleHumansImage Processing, Computer-AssistedMaleMiddle AgedNonlinear DynamicsPiperazinesPositron-Emission TomographyRadioligand AssayRadiopharmaceuticalsReceptors, sigmaReference StandardsConceptsPositron emission tomographyDistribution volumeTotal distribution volumeReference regionReceptor densityClinical investigationReceptor imagingSigma1 receptorsEmission tomographyAppropriate reference regionReceptorsTarget receptorsPhysiological situationsNeuroreceptor mappingHigh affinityImagingDVTDiseaseRadioligandBrainPET kinetic analysis: wavelet denoising of dynamic PET data with application to parametric imaging
Shidahara M, Ikoma Y, Kershaw J, Kimura Y, Naganawa M, Watabe H. PET kinetic analysis: wavelet denoising of dynamic PET data with application to parametric imaging. Annals Of Nuclear Medicine 2007, 21: 379. PMID: 17876550, DOI: 10.1007/s12149-007-0044-9.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAlgorithmsAnimalsArtifactsBrain MappingCluster AnalysisComputer SimulationCoronary CirculationFourier AnalysisHumansImage EnhancementImage Interpretation, Computer-AssistedImage Processing, Computer-AssistedKineticsNonlinear DynamicsNuclear MedicinePositron-Emission TomographyRadiopharmaceuticalsSoftwareTime FactorsMapping of human cerebral sigma1 receptors using positron emission tomography and [11C]SA4503
Sakata M, Kimura Y, Naganawa M, Oda K, Ishii K, Chihara K, Ishiwata K. Mapping of human cerebral sigma1 receptors using positron emission tomography and [11C]SA4503. NeuroImage 2007, 35: 1-8. PMID: 17240168, DOI: 10.1016/j.neuroimage.2006.11.055.Peer-Reviewed Original ResearchMeSH KeywordsAdultBiotransformationBrainBrain ChemistryBrain MappingChromatography, High Pressure LiquidData Interpretation, StatisticalDopamine AntagonistsHaloperidolHumansImage Processing, Computer-AssistedMaleNonlinear DynamicsPiperazinesPositron-Emission TomographyRadioligand AssayRadiopharmaceuticalsReceptors, sigmaConceptsTotal distribution volumePositron emission tomographyEmission tomographyMetabolite correctionHealthy male subjectsSigma receptor antagonistLogan plotHuman brainPlasma input functionReceptor antagonistOral administrationClinical studiesPET scansThree-compartment modelPartial blockadePsychiatric diseasesMale subjectsSigma1RSigma1 receptorsBaseline measurementsDistribution volumeTwo-tissueHaloperidolBrainReceptors
2005
MAP-based kinetic analysis for voxel-by-voxel compartment model estimation: Detailed imaging of the cerebral glucose metabolism using FDG
Kimura Y, Naganawa M, Yamaguchi J, Takabayashi Y, Uchiyama A, Oda K, Ishii K, Ishiwata K. MAP-based kinetic analysis for voxel-by-voxel compartment model estimation: Detailed imaging of the cerebral glucose metabolism using FDG. NeuroImage 2005, 29: 1203-1211. PMID: 16216532, DOI: 10.1016/j.neuroimage.2005.08.046.Peer-Reviewed Original ResearchAlgorithmsBlood GlucoseBrainBrain MappingComputer GraphicsComputer SimulationEnergy MetabolismFluorodeoxyglucose F18HumansImage Processing, Computer-AssistedImaging, Three-DimensionalKineticsLeast-Squares AnalysisNonlinear DynamicsPhantoms, ImagingPositron-Emission TomographyReproducibility of ResultsOmission of serial arterial blood sampling in neuroreceptor imaging with independent component analysis
Naganawa M, Kimura Y, Nariai T, Ishii K, Oda K, Manabe Y, Chihara K, Ishiwata K. Omission of serial arterial blood sampling in neuroreceptor imaging with independent component analysis. NeuroImage 2005, 26: 885-890. PMID: 15955498, DOI: 10.1016/j.neuroimage.2005.02.025.Peer-Reviewed Original ResearchConceptsArterial blood samplingBlood samplingCerebral glucose metabolismAdenosine A1 receptorsTotal distribution volumeSerial arterial blood samplingLogan plotPET imagesPlasma time-activity curveA1 receptorsHealthy subjectsGlucose metabolismTime-activity curvesDistribution volumeBrain diseasesDVTReference regionSubjectsParametric imagesDynamic PET images