2012
Functional connectivity studies of patients with auditory verbal hallucinations
Hoffman RE, Hampson M. Functional connectivity studies of patients with auditory verbal hallucinations. Frontiers In Human Neuroscience 2012, 6: 6. PMID: 22375109, PMCID: PMC3269039, DOI: 10.3389/fnhum.2012.00006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsAuditory verbal hallucinationsFunctional connectivity studiesFC studiesWernicke's areaVerbal hallucinationsConnectivity studiesLeft inferior frontal cortexInferior frontal cortexMagnetic resonance imaging dataFrontal cortexCorticostriatal loopsSeed regionPutamenFMRI dataAuditory stimuliRight homologueFunctional magnetic resonance imaging (fMRI) dataIntact FcHallucinationsPatientsBrain mechanismsNeural synchronizationFuture studiesHyperconnectivitySame subjects
2011
Time course of regional brain activity accompanying auditory verbal hallucinations in schizophrenia
Hoffman RE, Pittman B, Constable RT, Bhagwagar Z, Hampson M. Time course of regional brain activity accompanying auditory verbal hallucinations in schizophrenia. The British Journal Of Psychiatry 2011, 198: 277-283. PMID: 21972276, PMCID: PMC3065772, DOI: 10.1192/bjp.bp.110.086835.Peer-Reviewed Original ResearchConceptsInferior frontal gyrusAuditory verbal hallucinationsFrontal gyrusVerbal hallucinationsRegional brain activityTemporal regionsHallucination eventsBrain activityRight inferior frontal gyrusFunctional magnetic resonance imagingRight temporal activityRight posterior temporal regionPosterior temporal regionsEffects of motorNon-hallucinating patientsRight temporal regionHallucinations groupLeft temporal regionMagnetic resonance imagingTime courseCorollary dischargeGyrusVerbal imagesRegional activitySchizoaffective disorder
2010
Elevated Functional Connectivity Along a Corticostriatal Loop and the Mechanism of Auditory/Verbal Hallucinations in Patients with Schizophrenia
Hoffman RE, Fernandez T, Pittman B, Hampson M. Elevated Functional Connectivity Along a Corticostriatal Loop and the Mechanism of Auditory/Verbal Hallucinations in Patients with Schizophrenia. Biological Psychiatry 2010, 69: 407-414. PMID: 21145042, PMCID: PMC3039042, DOI: 10.1016/j.biopsych.2010.09.050.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsAntipsychotic AgentsCerebral CortexDiagnostic and Statistical Manual of Mental DisordersFemaleFrontal LobeHallucinationsHumansImage Processing, Computer-AssistedMagnetic Resonance ImagingMaleNeostriatumNeural PathwaysNeuropsychological TestsPutamenSchizophreniaSchizophrenic PsychologySocioeconomic FactorsTemporal LobeVerbal BehaviorConceptsHealthy control subjectsControl subjectsFunctional connectivityNonhallucinating patientsPatient groupInferior frontal gyrusAuditory/verbal hallucinationsCorticostriatal loopsElevated functional connectivityVerbal hallucinationsFalse discovery rate correctionFunctional magnetic resonancePatientsSubcortical regionsLeft inferior frontal gyrusSeed regionPutamenFrontal gyrusSpeech processing networkFunctional coordinationNeural activitySchizophreniaFC relativeHigh levelsHallucinations
2008
Time course of regional brain activation associated with onset of auditory/verbal hallucinations
Hoffman RE, Anderson AW, Varanko M, Gore JC, Hampson M. Time course of regional brain activation associated with onset of auditory/verbal hallucinations. The British Journal Of Psychiatry 2008, 193: 424-425. PMID: 18978327, PMCID: PMC2801815, DOI: 10.1192/bjp.bp.107.040501.Peer-Reviewed Original ResearchConceptsVerbal hallucinationsBrain activationRight middle temporal gyrusRegional brain activationLeft anterior insulaFunctional magnetic resonanceMiddle temporal gyrusPrevious case reportsAnterior insulaTemporal gyrusBrain eventsAnterior cingulateDextral patientsTime courseParahippocampal gyrusCase reportHallucinationsGyrusActivationMagnetic resonanceOnsetInsulaCingulate
2007
Probing the Pathophysiology of Auditory/Verbal Hallucinations by Combining Functional Magnetic Resonance Imaging and Transcranial Magnetic Stimulation
Hoffman RE, Hampson M, Wu K, Anderson AW, Gore JC, Buchanan RJ, Constable RT, Hawkins KA, Sahay N, Krystal JH. Probing the Pathophysiology of Auditory/Verbal Hallucinations by Combining Functional Magnetic Resonance Imaging and Transcranial Magnetic Stimulation. Cerebral Cortex 2007, 17: 2733-2743. PMID: 17298962, PMCID: PMC2634833, DOI: 10.1093/cercor/bhl183.Peer-Reviewed Original ResearchConceptsRepetitive transcranial magnetic stimulationTranscranial magnetic stimulationFunctional magnetic resonance imagingMagnetic resonance imagingMagnetic stimulationSham stimulationTemporoparietal repetitive transcranial magnetic stimulationAuditory/verbal hallucinationsResonance imagingWernicke's areaVerbal hallucinationsBOLD signal time coursesBroca's areaSchizophrenia spectrum disordersGreater rateInferior frontal regionsPatientsTemporoparietal areasSignal time courseCortical sitesPathophysiologySupramarginal gyrusHallucinationsRight homologueStimulation