2023
Neurofeedback for obsessive compulsive disorder: A randomized, double-blind trial
Rance M, Zhao Z, Zaboski B, Kichuk S, Romaker E, Koller W, Walsh C, Harris-Starling C, Wasylink S, Adams T, Gruner P, Pittenger C, Hampson M. Neurofeedback for obsessive compulsive disorder: A randomized, double-blind trial. Psychiatry Research 2023, 328: 115458. PMID: 37722238, PMCID: PMC10695074, DOI: 10.1016/j.psychres.2023.115458.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderAnterior prefrontal cortexControl groupDouble-blind clinical trialDouble-blind trialPrimary outcome measureCompulsive disorderHarm/checkingMechanism of actionYale-Brown ObsessiveSecondary outcomesSessions of neurofeedbackActive groupClinical trialsOutcome measuresPrimary symptomsSymptom ScaleObsessive-compulsive symptomsPrefrontal cortexSymptomsTraining protocolGreater reductionSignificant differencesPatientsSham feedback
2022
Obsessive compulsive symptom dimensions are linked to altered white-matter microstructure in a community sample of youth
Grazioplene RG, DeYoung CG, Hampson M, Anticevic A, Pittenger C. Obsessive compulsive symptom dimensions are linked to altered white-matter microstructure in a community sample of youth. Translational Psychiatry 2022, 12: 328. PMID: 35948535, PMCID: PMC9365814, DOI: 10.1038/s41398-022-02013-w.Peer-Reviewed Original ResearchConceptsWhite matter abnormalitiesObsessive-compulsive disorderObsessive-compulsive symptomsGeneral psychopathologyCorpus callosumWhite matterFractional anisotropyDistinct white matter abnormalitiesAnterior corpus callosumPosterior corpus callosumWhite matter correlatesAge-dependent mannerWhite matter measuresGeneral psychopathology factorWhite matter microstructure