2015
National Electrical Manufacturers Association and Clinical Evaluation of a Novel Brain PET/CT Scanner
Grogg K, Toole T, Ouyang J, Zhu X, Normandin M, Li Q, Johnson K, Alpert N, Fakhri G. National Electrical Manufacturers Association and Clinical Evaluation of a Novel Brain PET/CT Scanner. Journal Of Nuclear Medicine 2015, 57: 646-652. PMID: 26697961, PMCID: PMC4818715, DOI: 10.2967/jnumed.115.159723.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsBrainElectric Power SuppliesHumansNeuroimagingPhantoms, ImagingPositron-Emission TomographyReproducibility of ResultsSafetyScattering, RadiationConceptsNoise-equivalent count rateCount rateLoose cutsMaximum noise-equivalent counting rateSpatial resolutionDetector ringSilicon photomultipliersBrain phantomContrast recoveryAttenuation correctionPET/CT systemCrystal blockPET/CT scannerImage qualityRadial offsetNational Electrical Manufacturers AssociationActivity distributionUnique mobility capabilitiesAxial extentTransverse resolutionPhantomAxial resolutionActivity concentrationsHuman scansLayer 1 cm
2014
Towards coronary plaque imaging using simultaneous PET-MR: a simulation study
Petibon Y, Fakhri G, Nezafat R, Johnson N, Brady T, Ouyang J. Towards coronary plaque imaging using simultaneous PET-MR: a simulation study. Physics In Medicine And Biology 2014, 59: 1203-1222. PMID: 24556608, PMCID: PMC4061607, DOI: 10.1088/0031-9155/59/5/1203.Peer-Reviewed Original ResearchMeSH KeywordsComputer SimulationCoronary AngiographyCoronary StenosisHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance AngiographyModels, CardiovascularMultimodal ImagingPhantoms, ImagingPositron-Emission TomographyReproducibility of ResultsSensitivity and SpecificityConceptsSimultaneous PET-MRChannelized Hotelling observerAttenuation mapMotion correctionPET-MRFluorodeoxyglucose-positron emission tomography imagingRespiratory motion fieldsMotion correction methodCho SNRMotion correction techniqueAnthropomorphic phantomUncorrected reconstructionsRespiratory motionXCAT phantomCoronary plaque imagingMonte Carlo simulationsPET reconstructionXCATActivity distributionCardiac gatingNon-rigid registrationHotelling observerCarlo simulationsPlaque imagingPhantom
2008
Improved activity estimation with MC‐JOSEM versus TEW‐JOSEM in SPECT
Ouyang J, Fakhri G, Moore S. Improved activity estimation with MC‐JOSEM versus TEW‐JOSEM in SPECT. Medical Physics 2008, 35: 2029-2040. PMID: 18561679, PMCID: PMC2673642, DOI: 10.1118/1.2907561.Peer-Reviewed Original ResearchMeSH KeywordsAlgorithmsEquipment DesignImage Processing, Computer-AssistedIndium RadioisotopesLungModels, StatisticalMonte Carlo MethodPhantoms, ImagingRadiotherapy Planning, Computer-AssistedReproducibility of ResultsScattering, RadiationSoftwareTomography, Emission-Computed, Single-PhotonTomography, X-Ray ComputedConceptsMC-JOSEMWater-filled torso phantomMC scatter estimationTriple-energy-windowActivity estimationIterative reconstruction algorithmTorso phantomPhantom studyBackground compartmentScatter estimationActivity distributionAverage relative biasPhantomReconstruction algorithmActivity concentrationsSynthetic projectionsSphere locationScattering
2006
Generalized five‐dimensional dynamic and spectral factor analysis
Fakhri G, Sitek A, Zimmerman R, Ouyang J. Generalized five‐dimensional dynamic and spectral factor analysis. Medical Physics 2006, 33: 1016-1024. PMID: 16696478, DOI: 10.1118/1.2179168.Peer-Reviewed Original Research
2005
Performance of a novel collimator for high‐sensitivity brain SPECT
Fakhri G, Ouyang J, Zimmerman R, Fischman A, Kijewski M. Performance of a novel collimator for high‐sensitivity brain SPECT. Medical Physics 2005, 33: 209-215. PMID: 16485427, DOI: 10.1118/1.2143140.Peer-Reviewed Original ResearchConceptsSphere activity concentrationNPW-SNRStandard collimatorSphere-to-background activity ratiosAttenuation of countsPhantom centerActivity concentrationsPoint spread functionCentral regionCollimatorPhantom studyStriatal phantomCylindrical backgroundResolution recoveryPhantomSpherical lesionsRamp filterCrystal surfaceSpread functionSignal-to-noise ratioCentral brain structuresFitting imageHealthy volunteersBrain SPECTSphere activity