2020
Prospective, longitudinal digital activity monitoring before and after treatment of low-risk oropharyngeal squamous cell carcinoma: A feasibility study.
Gunn G, Ferrarotto R, Johnson F, Bell D, Cardoso R, Johnson J, Rubin M, Yuan Y, Frank S, Fuller C, Rosenthal D, Kupferman M, Goepfert R, Hessel A, Hutcheson K, Gross N. Prospective, longitudinal digital activity monitoring before and after treatment of low-risk oropharyngeal squamous cell carcinoma: A feasibility study. Journal Of Clinical Oncology 2020, 38: 6578-6578. DOI: 10.1200/jco.2020.38.15_suppl.6578.Peer-Reviewed Original ResearchOropharyngeal squamous cell carcinomaTransoral robotic surgeryIntensity-modulated proton therapySquamous cell carcinomaKcal/dayOverall cohortCell carcinomaFunctional outcomeMedian age 59 yearsSubjective patient-reported outcome measuresPatient-reported outcome measuresActiGraph accelerometer dataParallel cohort studyAge 59 yearsDe-escalation trialsObjective functional outcomesSingle modality treatmentTime of presentationUntreated stage ISignificant decreaseVigorous physical activitySteps/minuteLong-term toxicityCohort studyExcellent prognosis
2018
Significance of Negative Posttreatment 18-FDG PET/CT Imaging in Patients With p16/HPV-Positive Oropharyngeal Cancer
Ng S, Johnson J, Gunn G, Rosenthal D, Skinner H, Phan J, Frank S, Morrison W, Sturgis E, Mott F, Williams M, Fuller C, Garden A. Significance of Negative Posttreatment 18-FDG PET/CT Imaging in Patients With p16/HPV-Positive Oropharyngeal Cancer. International Journal Of Radiation Oncology • Biology • Physics 2018, 102: 1029-1035. PMID: 29960060, PMCID: PMC9620951, DOI: 10.1016/j.ijrobp.2018.06.031.Peer-Reviewed Original ResearchConceptsOropharyngeal squamous cell carcinomaComplete metabolic responseDisease-free survivalOverall survival rateSquamous cell carcinomaCell carcinomaTomography scanSurvival rateHPV-positive oropharyngeal cancerCommon primary siteHPV/p16Posttreatment PET imagingPosttreatment PET scansKaplan-Meier methodSubgroup of patientsBase of tongueGroup of patientsHuman papilloma virusDevelopment of recurrencePET/CT imagingMetabolic responseOptimal surveillance strategyPositron emission tomographyLonger life expectancyEleven patients