2019
Risk of second primary malignancies in head and neck cancer patients treated with definitive radiotherapy
Ng S, Pollard C, Kamal M, Ayoub Z, Garden A, Bahig H, Gunn G, Frank S, Skinner H, Phan J, Berends J, Morrison W, Johnson J, Ferrarotto R, Sturgis E, Mohamed A, Lai S, Fuller C, Rosenthal D. Risk of second primary malignancies in head and neck cancer patients treated with definitive radiotherapy. Npj Precision Oncology 2019, 3: 22. PMID: 31583278, PMCID: PMC6764977, DOI: 10.1038/s41698-019-0097-y.Peer-Reviewed Original ResearchSecond primary malignanciesDefinitive radiotherapyFormer smokersCurrent smokersOverall survivalPrimary malignancyRisk of SPMCurative-intent therapyIndex oropharyngeal cancersCompletion of radiotherapySignificant smoking historyKaplan-Meier methodMajority of patientsNeck cancer patientsSame risk factorsNeck cancer treatmentEligible patientsSPM ratesPack yearsSmoking historyOropharyngeal cancerInvasive cancerCancer patientsRisk factorsClinical dataUsefulness of surveillance imaging in patients with head and neck cancer who are treated with definitive radiotherapy
Ng S, Pollard C, Berends J, Ayoub Z, Kamal M, Garden A, Bahig H, Cantor S, Schaefer A, Ajayi T, Gunn G, Frank S, Skinner H, Phan J, Morrison W, Ferrarotto R, Johnson J, Mohamed A, Lai S, Hessel A, Sturgis E, Weber R, Fuller C, Rosenthal D. Usefulness of surveillance imaging in patients with head and neck cancer who are treated with definitive radiotherapy. Cancer 2019, 125: 1823-1829. PMID: 30748005, PMCID: PMC7234834, DOI: 10.1002/cncr.31983.Peer-Reviewed Original ResearchConceptsDisease recurrenceAsymptomatic patientsOverall survivalClinical findingsNeck cancerAdverse clinical findingsLocoregional disease recurrenceMedian imaging followUsefulness of surveillanceDisease-free intervalMedian overall survivalDistant disease recurrenceGroup of patientsEfficacy of surveillanceTreatment of HNCEligible patientsSalvage therapySalvageable recurrenceDefinitive radiotherapyMedian timeSuspicious findingsPatientsRecurrenceRadiotherapyEarly detection
2017
Cost of surveillance imaging in head and neck cancer patients treated with definitive radiotherapy.
Ng S, Jomaa M, Pollard C, Ayoub Z, Mohamed A, Garden A, Berends J, Gunn G, Frank S, Skinner H, Phan J, Rosenthal D, Morrison W, Johnson J, Sturgis E, Lai S, Fuller C. Cost of surveillance imaging in head and neck cancer patients treated with definitive radiotherapy. Journal Of Clinical Oncology 2017, 35: 6610-6610. DOI: 10.1200/jco.2017.35.15_suppl.6610.Peer-Reviewed Original ResearchNeck cancer patientsSalvageable recurrenceAsymptomatic patientsDefinitive radiotherapyOverall survivalClinical findingsCancer patientsAdverse clinical findingsEarly salvage treatmentRecurrence-related deathsSuccessful salvage rateDisease-free intervalMedian overall survivalGroup of patientsChemotherapy useEligible patientsLR relapseSalvage therapyDistant relapseSalvage treatmentDisease recurrenceSalvage rateClinical outcomesMedian timeMean age