2020
Imaging of Injectable Hydrogels Delivered into Myocardium with SPECT/CT
Uman S, Wang LL, Thorn SL, Liu Z, Duncan JS, Sinusas AJ, Burdick JA. Imaging of Injectable Hydrogels Delivered into Myocardium with SPECT/CT. Advanced Healthcare Materials 2020, 9: e2000294. PMID: 32543053, PMCID: PMC7482444, DOI: 10.1002/adhm.202000294.Peer-Reviewed Original ResearchConceptsInjectable hydrogelsMyocardial infarctionSelf-healing hydrogelsHydrogel mechanical propertiesHybrid single-photon emissionHybrid SPECT/CT imagingMechanical propertiesTomography perfusion imagingAcute porcine modelSPECT/CT imagingSPECT/CTSingle photon emissionInjection forceHyaluronic acid hydrogelsPattern of deliveryTomography/HydrogelsPerfusion defectsPerfusion imagingExcellent radiopacityPorcine modelAcid hydrogelsCT imagingHydrogel deliveryHydrogel injection
1997
Positron Emission Tomography Measurement of Cerebral Metabolic Correlates of Tryptophan Depletion—Induced Depressive Relapse
Bremner JD, Innis RB, Salomon RM, Staib LH, Ng CK, Miller HL, Bronen RA, Krystal JH, Duncan J, Rich D, Price LH, Malison R, Dey H, Soufer R, Charney DS. Positron Emission Tomography Measurement of Cerebral Metabolic Correlates of Tryptophan Depletion—Induced Depressive Relapse. JAMA Psychiatry 1997, 54: 364-374. PMID: 9107153, DOI: 10.1001/archpsyc.1997.01830160092012.Peer-Reviewed Original ResearchConceptsCerebral metabolic correlatesDepressive relapseBrain metabolismMajor depressionMiddle frontal gyrusOrbitofrontal cortexTryptophan depletionMetabolic correlatesPositron emission tomography scanningFrontal gyrusRelapse-prone patientsPathogenesis of depressionPositron emission tomography (PET) measurementsSerotonin reuptake inhibitorsSymptoms of patientsPositron emission tomographySingle photon emissionSpecific brain regionsDorsolateral prefrontal cortexReuptake inhibitorsPlasma tryptophanLimbic regionsCaudate nucleusDepressive symptomsPatients