2018
Brain Biomarker Interpretation in ASD Using Deep Learning and fMRI
Li X, Dvornek NC, Zhuang J, Ventola P, Duncan JS. Brain Biomarker Interpretation in ASD Using Deep Learning and fMRI. Lecture Notes In Computer Science 2018, 11072: 206-214. PMID: 32984865, PMCID: PMC7519581, DOI: 10.1007/978-3-030-00931-1_24.Peer-Reviewed Original ResearchDeep neural networksFunctional magnetic resonance imagingBrain functional magnetic resonance imagingAutism spectrum disorderComputer visionDeep learningDNN classifierMagnetic resonance imagingCorrupt imagesNeural networkSaliency featuresClassification scenariosNeurological functionControl subjectsComplex neurodevelopmental disorderEarly diagnosisComputational decisionReliable biomarkersResonance imagingBiomarker interpretationBiomarkersDetected biomarkersNeurodevelopmental disordersBrain featuresClassifier
1997
Positron Emission Tomography Measurement of Cerebral Metabolic Correlates of Yohimbine Administration in Combat-Related Posttraumatic Stress Disorder
Bremner JD, Innis RB, Ng CK, Staib LH, Salomon RM, Bronen RA, Duncan J, Southwick SM, Krystal JH, Rich D, Zubal G, Dey H, Soufer R, Charney DS. Positron Emission Tomography Measurement of Cerebral Metabolic Correlates of Yohimbine Administration in Combat-Related Posttraumatic Stress Disorder. JAMA Psychiatry 1997, 54: 246-254. PMID: 9075465, DOI: 10.1001/archpsyc.1997.01830150070011.Peer-Reviewed Original ResearchConceptsPosttraumatic stress disorderAdministration of yohimbineNorepinephrine releaseHealthy subjectsHealthy age-matched control subjectsAge-matched control subjectsStress disorderDouble-blind fashionPositron emission tomography (PET) measurementsBrain metabolic responsesCerebral metabolic correlatesBrain norepinephrine releaseSymptoms of anxietyPositron emission tomographyBrain metabolismControl subjectsYohimbine administrationPreclinical studiesMetabolic correlatesCaudate nucleusPatientsYohimbineVietnam combat veteransEmission tomographyOrbitofrontal cortex