2006
Neuroimaging of emotional brain circuitry in bipolar disorder
Weder N, Chepenik L, Kalmar J, Blumberg H. Neuroimaging of emotional brain circuitry in bipolar disorder. Current Psychosis And Therapeutics Reports 2006, 4: 159-166. DOI: 10.1007/bf02629390.Peer-Reviewed Original ResearchNeural systemsVentral striatumRegulation of emotionEmotional brain circuitryVentral prefrontal cortexBipolar disorderMotivational behaviorPrefrontal cortexNeurodevelopmental trajectoriesCore featuresBrain circuitryMood-stabilizing medicationsBrain regionsBrain structuresPathophysiologic mechanismsResearch directionsNew research directionsRegional abnormalitiesBeneficial effectsAbnormalitiesEmotionsDisordersStriatumCircuitryAdolescents
2000
Increased anterior cingulate and caudate activity in bipolar mania
Blumberg H, Stern E, Martinez D, Ricketts S, de Asis J, White T, Epstein J, McBride P, Eidelberg D, Kocsis J, Silbersweig D. Increased anterior cingulate and caudate activity in bipolar mania. Biological Psychiatry 2000, 48: 1045-1052. PMID: 11094137, DOI: 10.1016/s0006-3223(00)00962-8.Peer-Reviewed Original ResearchConceptsManic stateAnterior cingulateBipolar disorderHead of caudateFunctional brain abnormalitiesPositron emission tomography techniquesDorsal anterior cingulateEmission tomography techniquesBipolar maniaBrain abnormalitiesSuch dysfunctionCingulateDisordersBrain activityCaudate activityCaudateManiaNeural systemsPrincipal findingsDysfunctionActivityAbnormalitiesEuthymiaExecutive controlFindings