2014
Towards coronary plaque imaging using simultaneous PET-MR: a simulation study
Petibon Y, Fakhri G, Nezafat R, Johnson N, Brady T, Ouyang J. Towards coronary plaque imaging using simultaneous PET-MR: a simulation study. Physics In Medicine And Biology 2014, 59: 1203-1222. PMID: 24556608, PMCID: PMC4061607, DOI: 10.1088/0031-9155/59/5/1203.Peer-Reviewed Original ResearchMeSH KeywordsComputer SimulationCoronary AngiographyCoronary StenosisHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalMagnetic Resonance AngiographyModels, CardiovascularMultimodal ImagingPhantoms, ImagingPositron-Emission TomographyReproducibility of ResultsSensitivity and SpecificityConceptsSimultaneous PET-MRChannelized Hotelling observerAttenuation mapMotion correctionPET-MRFluorodeoxyglucose-positron emission tomography imagingRespiratory motion fieldsMotion correction methodCho SNRMotion correction techniqueAnthropomorphic phantomUncorrected reconstructionsRespiratory motionXCAT phantomCoronary plaque imagingMonte Carlo simulationsPET reconstructionXCATActivity distributionCardiac gatingNon-rigid registrationHotelling observerCarlo simulationsPlaque imagingPhantom
2005
Quantitative dynamic cardiac 82Rb PET using generalized factor and compartment analyses.
El Fakhri G, Sitek A, Guérin B, Kijewski M, Di Carli M, Moore S. Quantitative dynamic cardiac 82Rb PET using generalized factor and compartment analyses. Journal Of Nuclear Medicine 2005, 46: 1264-71. PMID: 16085581.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overAlgorithmsComputer SimulationCoronary Artery DiseaseFeasibility StudiesFemaleHeartHumansImage Interpretation, Computer-AssistedMaleMiddle AgedModels, CardiovascularPositron-Emission TomographyRadiopharmaceuticalsReproducibility of ResultsRubidium RadioisotopesSensitivity and SpecificitySeverity of Illness IndexConceptsMyocardial perfusionAbsolute myocardial perfusionCatheterization resultsMyocardial tissue extractsDipyridamole stressCardiac PETClinical valueMyocardial factorsFactor analysis of dynamic sequencesPatient studiesLVNoninvasive estimationAccurate input functionPatientsCompartment analysisAverage errorPerfusionParametric mappingTissue extractsRV contributionRV
1999
Respective roles of scatter, attenuation, depth-dependent collimator response and finite spatial resolution in cardiac single-photon emission tomography quantitation: a Monte Carlo study
El Fakhri G, Buvat I, Pélégrini M, Benali H, Almeida P, Bendriem B, Todd-Pokropek A, Di Paola R. Respective roles of scatter, attenuation, depth-dependent collimator response and finite spatial resolution in cardiac single-photon emission tomography quantitation: a Monte Carlo study. European Journal Of Nuclear Medicine And Molecular Imaging 1999, 26: 437-446. PMID: 10382086, DOI: 10.1007/s002590050409.Peer-Reviewed Original ResearchConceptsDepth-dependent collimator responseCollimator responseMonte Carlo simulationsActivity underestimationSingle-photon emission tomographyCarlo simulationsSignal-to-noise ratioSpatial resolutionCardiac phantomFWHM spatial resolutionCardiac single-photon emission tomographyQuantitative accuracyAnthropomorphic cardiac phantomPhysical effectsInfluence of scatteringEffect of scatteringScatter countsFull-widthIncreased SNRPoor spatial resolutionScatteringMap homogeneityPhantomMonteImaging system